Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Travere Therapeutics, Inc.(TVTX) | 3,763,891 | 4,897,417 | +1,133,526 | $143.82M | $145.50M | 4.80% | +$1.68M |
| PTC Therapeutics, Inc.(PTCT) | 2,801,869 | 2,074,449 | -727,420 | $212.83M | $141.33M | 4.67% | -$71.50M |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 265,705 | 264,583 | -1,122 | $154.73M | $138.50M | 4.57% | -$16.23M |
| Supernus Pharmaceuticals, Inc.(SUPN) | 2,764,000 | 1,895,347 | -868,653 | $137.37M | $97.97M | 3.23% | -$39.40M |
| Neurocrine Biosciences, Inc.(NBIX) | 820,240 | 724,000 | -96,240 | $116.33M | $95.38M | 3.15% | -$20.95M |
| Agios Pharmaceuticals, Inc.(AGIO) | 3,036,000 | 2,716,000 | -320,000 | $82.64M | $91.88M | 3.03% | +$9.24M |
| Immunovant, Inc.(IMVT) | 5,747,155 | 3,564,916 | -2,182,239 | $146.09M | $88.55M | 2.92% | -$57.54M |
| Freshpet, Inc.(FRPT) | 1,296,000 | 1,093,307 | -202,693 | $78.97M | $64.46M | 2.13% | -$14.50M |
| Incyte Corporation(INCY) | 1,098,102 | 656,817 | -441,285 | $108.46M | $61.82M | 2.04% | -$46.64M |
| Dyne Therapeutics, Inc.(DYN) | 3,249,708 | 3,175,110 | -74,598 | $63.56M | $57.56M | 1.90% | -$6.00M |
| Amazon.com, Inc.(AMZN) | 367,633 | 262,137 | -105,496 | $84.86M | $54.60M | 1.80% | -$30.26M |
| Ironwood Pharmaceuticals, Inc.CL A(IRWD) | 16,025,000 | 15,028,000 | -997,000 | $54.00M | $52.75M | 1.74% | -$1.26M |
| Cytokinetics, Incorporated(CYTK) | 992,766 | 764,538 | -228,228 | $63.08M | $50.39M | 1.66% | -$12.69M |
| Harmony Biosciences Holdings, Inc.(HRMY) | 500,000 | 1,624,000 | +1,124,000 | $18.71M | $45.49M | 1.50% | +$26.78M |
| Thermo Fisher Scientific Inc.(TMO) | 62,838 | 91,491 | +28,653 | $36.41M | $44.97M | 1.48% | +$8.56M |
| Nektar Therapeutics(NKTR) | 596,000 | 578,000 | -18,000 | $25.20M | $41.59M | 1.37% | +$16.39M |
| UnitedHealth Group Incorporated(UNH) | 0 | 148,000 | +148,000 | $0 | $40.05M | 1.32% | +$40.05M |
| Uber Technologies, Inc.(UBER) | 282,734 | 518,760 | +236,026 | $23.10M | $37.31M | 1.23% | +$14.21M |
| Immunocore Holdings plcADS(IMCR) | 1,098,000 | 1,188,000 | +90,000 | $38.11M | $35.82M | 1.18% | -$2.29M |
| DENTSPLY SIRONA Inc.(XRAY) | 7,298,000 | 3,000,000 | -4,298,000 | $83.42M | $34.80M | 1.15% | -$48.62M |
| Rigel Pharmaceuticals, Inc.(RIGL) | 836,000 | 1,280,000 | +444,000 | $35.81M | $34.61M | 1.14% | -$1.19M |
| Disc Medicine, Inc.(IRON) | 499,391 | 536,000 | +36,609 | $39.66M | $34.27M | 1.13% | -$5.38M |
| Alphabet Inc.CL A(GOOG) | 196,420 | 118,514 | -77,906 | $61.48M | $34.08M | 1.13% | -$27.40M |
| Mineralys Therapeutics, Inc.(MLYS) | 676,035 | 1,176,000 | +499,965 | $24.53M | $31.86M | 1.05% | +$7.32M |
| HubSpot, Inc.(HUBS) | 68,000 | 128,583 | +60,583 | $27.29M | $31.39M | 1.04% | +$4.10M |
| Axogen, Inc.(AXGN) | 936,000 | 936,000 | 0 | $30.64M | $31.01M | 1.02% | +$374.4K |
| Orthofix Medical Inc.(OFIX) | 2,648,000 | 2,700,000 | +52,000 | $40.14M | $30.97M | 1.02% | -$9.17M |
| Kura Oncology, Inc.(KURA) | 4,936,000 | 3,736,000 | -1,200,000 | $51.29M | $30.37M | 1.00% | -$20.91M |
| Avanos Med Inc | 3,200,000 | 2,000,000 | -1,200,000 | $35.94M | $28.02M | 0.93% | -$7.92M |
| Regeneron Pharmaceuticals, Inc.(REGN) | 84,000 | 36,126 | -47,874 | $64.84M | $27.91M | 0.92% | -$36.92M |
| Align Technology Inc | 76,104 | 157,959 | +81,855 | $11.88M | $27.08M | 0.89% | +$15.20M |
| MongoDB, Inc.CL A(MDB) | 49,144 | 107,296 | +58,152 | $20.63M | $26.26M | 0.87% | +$5.64M |
| Alibaba Group Holding LimitedADS(BABA) | 319,100 | 204,000 | -115,100 | $46.77M | $25.59M | 0.84% | -$21.18M |
| Medline Inc.CL A(MDLN) | 58,016 | 564,857 | +506,841 | $2.44M | $25.14M | 0.83% | +$22.70M |
| Kalvista Pharmaceuticals Inc | 800,000 | 1,236,000 | +436,000 | $12.92M | $24.88M | 0.82% | +$11.96M |
| Datadog, Inc.CL A(DDOG) | 244,537 | 208,564 | -35,973 | $33.25M | $24.62M | 0.81% | -$8.63M |
| Humana Inc.(HUM) | 71,697 | 141,279 | +69,582 | $18.36M | $24.50M | 0.81% | +$6.13M |
| SentinelOne, Inc.CL A(S) | 2,422,219 | 1,897,849 | -524,370 | $36.33M | $24.44M | 0.81% | -$11.89M |
| Verastem, Inc.(VSTM) | 3,536,000 | 4,592,000 | +1,056,000 | $27.30M | $24.34M | 0.80% | -$2.96M |
| Five9, Inc.(FIVN) | 2,000,000 | 1,592,000 | -408,000 | $40.10M | $24.15M | 0.80% | -$15.95M |
| Intuitive Surgical, Inc.(ISRG) | 61,073 | 52,043 | -9,030 | $34.59M | $23.99M | 0.79% | -$10.60M |
| Grifols, S.A.ADR(GRFS) | 2,768,000 | 2,988,000 | +220,000 | $25.88M | $23.96M | 0.79% | -$1.92M |
| PENN Entertainment, Inc.(PENN) | 3,096,000 | 1,578,000 | -1,518,000 | $45.67M | $23.72M | 0.78% | -$21.95M |
| Solid Biosciences Inc | 2,612,000 | 3,200,000 | +588,000 | $14.73M | $23.04M | 0.76% | +$8.31M |
| GitLab Inc.CL A(GTLB) | 858,925 | 1,028,664 | +169,739 | $32.24M | $22.26M | 0.73% | -$9.98M |
| Autolus Therapeutics plcADS(AUTL) | 17,500,000 | 15,800,000 | -1,700,000 | $34.83M | $21.80M | 0.72% | -$13.02M |
| AngioDynamics, Inc.(ANGO) | 1,700,000 | 1,869,000 | +169,000 | $21.83M | $21.25M | 0.70% | -$577.5K |
| Arvinas, Inc.(ARVN) | 1,800,000 | 1,978,000 | +178,000 | $21.35M | $20.97M | 0.69% | -$381.2K |
| Taiwan Semiconductor Manufacturing Company LimitedADS(TSM) | 50,000 | 61,254 | +11,254 | $15.19M | $20.70M | 0.68% | +$5.51M |
| Alto Neuroscience, Inc.(ANRO) | 1,536,000 | 912,000 | -624,000 | $27.34M | $20.50M | 0.68% | -$6.84M |
| Energizer Holdings, Inc.(ENR) | 1,036,000 | 1,200,000 | +164,000 | $20.61M | $19.70M | 0.65% | -$902.0K |
| Meta Platforms, Inc.CL A(META) | 0 | 32,594 | +32,594 | $0 | $18.65M | 0.62% | +$18.65M |
| 4d Molecular Therapeutics In | 1,936,000 | 2,000,000 | +64,000 | $14.52M | $18.62M | 0.61% | +$4.10M |
| Microsoft Corporation(MSFT) | 118,337 | 48,860 | -69,477 | $57.23M | $18.09M | 0.60% | -$39.14M |
| Edwards Lifesciences Corp | 277,478 | 224,835 | -52,643 | $23.66M | $18.00M | 0.59% | -$5.65M |
| Wynn Resorts, Limited(WYNN) | 176,190 | 173,545 | -2,645 | $21.20M | $17.62M | 0.58% | -$3.58M |
| MacroGenics, Inc.(MGNX) | 6,324,000 | 6,012,000 | -312,000 | $10.18M | $17.37M | 0.57% | +$7.19M |
| Scholar Rock Holding Corporation(SRRK) | 200,000 | 336,959 | +136,959 | $8.81M | $16.56M | 0.55% | +$7.75M |
| Bicycle Therapeutics PlcADS | 3,236,000 | 3,398,000 | +162,000 | $22.91M | $15.77M | 0.52% | -$7.14M |
| Central Garden & Pet CompanyCL A(CENT) | 0 | 478,000 | +478,000 | $0 | $15.50M | 0.51% | +$15.50M |
| Lennar CorporationCL A(LEN) | 151,295 | 177,013 | +25,718 | $15.55M | $15.37M | 0.51% | -$181.3K |
| Toast, Inc.CL A(TOST) | 227,753 | 577,471 | +349,718 | $8.09M | $15.31M | 0.51% | +$7.22M |
| SanofiADR(SNY) | 676,000 | 300,000 | -376,000 | $32.76M | $14.45M | 0.48% | -$18.30M |
| Bill Holdings Inc | 271,389 | 374,908 | +103,519 | $14.80M | $14.36M | 0.47% | -$442.6K |
| UiPath, Inc.CL A(PATH) | 1,524,617 | 1,284,720 | -239,897 | $24.99M | $14.26M | 0.47% | -$10.73M |
| Voyager Therapeutics, Inc.(VYGR) | 4,000,000 | 3,500,000 | -500,000 | $15.72M | $13.51M | 0.45% | -$2.21M |
| GSK plcADR(GSK) | 1,000,000 | 236,000 | -764,000 | $49.04M | $13.02M | 0.43% | -$36.02M |
| Teradyne, Inc.(TER) | 28,302 | 43,932 | +15,630 | $5.48M | $13.02M | 0.43% | +$7.55M |
| Crocs, Inc.(CROX) | 190,350 | 154,593 | -35,757 | $16.28M | $12.83M | 0.42% | -$3.44M |
| NIKE, Inc.CL B(NKE) | 394,709 | 236,540 | -158,169 | $25.15M | $12.49M | 0.41% | -$12.65M |
| Bristol-Myers Squibb Company(BMY) | 372,466 | 205,024 | -167,442 | $20.09M | $12.43M | 0.41% | -$7.66M |
| Vera Therapeutics, Inc.CL A(VERA) | 653,796 | 298,164 | -355,632 | $33.11M | $12.00M | 0.40% | -$21.11M |
| BridgeBio Oncology Therapeutics, Inc.(BBOT) | 1,000,000 | 1,328,000 | +328,000 | $12.52M | $11.89M | 0.39% | -$634.4K |
| Capri Holdings LimitedSHS SHS | 0 | 658,000 | +658,000 | $0 | $11.59M | 0.38% | +$11.59M |
| Nebius Group N.V.CL A(NBIS) | 267,421 | 108,000 | -159,421 | $22.38M | $11.21M | 0.37% | -$11.18M |
| Xeris Biopharma Holdings Inc | 0 | 1,909,838 | +1,909,838 | $0 | $11.08M | 0.37% | +$11.08M |
| Esperion Therapeutics Inc Ne | 0 | 3,930,125 | +3,930,125 | $0 | $10.77M | 0.36% | +$10.77M |
| IQVIA Holdings Inc.(IQV) | 0 | 60,884 | +60,884 | $0 | $10.38M | 0.34% | +$10.38M |
| Ross Stores, Inc.(ROST) | 111,034 | 47,908 | -63,126 | $20.00M | $10.38M | 0.34% | -$9.62M |
| NVIDIA Corporation(NVDA) | 63,955 | 59,269 | -4,686 | $11.93M | $10.34M | 0.34% | -$1.59M |
| Sangamo Therapeutics, Inc.(SGMOQ) | 0 | 40,400,067 | +40,400,067 | $0 | $9.97M | 0.33% | +$9.97M |
| Intel Corporation(INTC) | 122,936 | 223,995 | +101,059 | $4.54M | $9.88M | 0.33% | +$5.35M |
| AppLovin CorporationCL A(APP) | 22,262 | 24,422 | +2,160 | $15.00M | $9.72M | 0.32% | -$5.28M |
| Workday, Inc.CL A(WDAY) | 93,893 | 73,995 | -19,898 | $20.17M | $9.61M | 0.32% | -$10.55M |
| Reddit, Inc.CL A(RDDT) | 76,600 | 70,000 | -6,600 | $17.61M | $9.43M | 0.31% | -$8.18M |
| NeuroPace, Inc.(NPCE) | 792,000 | 692,000 | -100,000 | $12.23M | $9.10M | 0.30% | -$3.13M |
| Zura Bio LimitedCL A(ZURA) | 1,560,000 | 1,507,000 | -53,000 | $8.17M | $8.97M | 0.30% | +$792.3K |
| Pegasystems Inc.(PEGA) | 131,994 | 210,429 | +78,435 | $7.88M | $8.96M | 0.30% | +$1.07M |
| Generac Holdings Inc.(GNRC) | 0 | 44,902 | +44,902 | $0 | $8.77M | 0.29% | +$8.77M |
| Treace Medical Concepts, Inc.(TMCI) | 6,364,000 | 6,364,000 | 0 | $15.59M | $8.53M | 0.28% | -$7.06M |
| GE HealthCare Technologies Inc.(GEHC) | 792,000 | 118,289 | -673,711 | $64.96M | $8.42M | 0.28% | -$56.54M |
| Micron Technology, Inc.(MU) | 0 | 23,293 | +23,293 | $0 | $7.87M | 0.26% | +$7.87M |
| Tenax Therapeutics, Inc.(TENX) | 0 | 478,827 | +478,827 | $0 | $7.66M | 0.25% | +$7.66M |
| Nuvation Bio Inc.CL A(NUVB) | 1,263,737 | 1,736,000 | +472,263 | $11.32M | $7.45M | 0.25% | -$3.88M |
| Inogen, Inc.(INGN) | 1,264,000 | 1,200,000 | -64,000 | $8.49M | $7.42M | 0.24% | -$1.08M |
| O'Reilly Automotive, Inc.(ORLY) | 91,111 | 78,103 | -13,008 | $8.31M | $7.21M | 0.24% | -$1.10M |
| Kymera Therapeutics, Inc.(KYMR) | 81,165 | 83,876 | +2,711 | $6.32M | $6.99M | 0.23% | +$670.6K |
| Dogwood Therapeutics, Inc.(DWTX) | 0 | 3,280,000 | +3,280,000 | $0 | $6.92M | 0.23% | +$6.92M |
| RH(RH) | 115,000 | 48,000 | -67,000 | $20.60M | $6.71M | 0.22% | -$13.89M |
| Envista Holdings Corporation(NVST) | 0 | 264,008 | +264,008 | $0 | $6.70M | 0.22% | +$6.70M |