Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| PTC Therapeutics, Inc.(PTCT) | 3,277,272 | 2,801,869 | -475,403 | $201.13M | $212.83M | 5.21% | +$11.70M |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 119,982 | 265,705 | +145,723 | $55.03M | $154.73M | 3.79% | +$99.70M |
| Immunovant, Inc.(IMVT) | 5,836,000 | 5,747,155 | -88,845 | $94.08M | $146.09M | 3.58% | +$52.02M |
| Travere Therapeutics, Inc.(TVTX) | 6,724,000 | 3,763,891 | -2,960,109 | $160.70M | $143.82M | 3.52% | -$16.89M |
| Supernus Pharmaceuticals, Inc.(SUPN) | 2,836,000 | 2,764,000 | -72,000 | $135.53M | $137.37M | 3.36% | +$1.84M |
| Neurocrine Biosciences, Inc.(NBIX) | 697,022 | 820,240 | +123,218 | $97.85M | $116.33M | 2.85% | +$18.49M |
| Incyte Corporation(INCY) | 1,167,431 | 1,098,102 | -69,329 | $99.01M | $108.46M | 2.66% | +$9.45M |
| Amazon.com, Inc.(AMZN) | 309,400 | 367,633 | +58,233 | $67.93M | $84.86M | 2.08% | +$16.92M |
| DENTSPLY SIRONA Inc.(XRAY) | 5,736,000 | 7,298,000 | +1,562,000 | $72.79M | $83.42M | 2.04% | +$10.63M |
| Agios Pharmaceuticals, Inc.(AGIO) | 764,000 | 3,036,000 | +2,272,000 | $30.67M | $82.64M | 2.02% | +$51.97M |
| Freshpet, Inc.(FRPT) | 1,234,802 | 1,296,000 | +61,198 | $68.05M | $78.97M | 1.93% | +$10.92M |
| Kenvue Inc.(KVUE) | 0 | 3,992,196 | +3,992,196 | $0 | $68.87M | 1.69% | +$68.87M |
| GE HealthCare Technologies Inc.(GEHC) | 795,053 | 792,000 | -3,053 | $59.71M | $64.96M | 1.59% | +$5.25M |
| Regeneron Pharmaceuticals, Inc.(REGN) | 125,206 | 84,000 | -41,206 | $70.40M | $64.84M | 1.59% | -$5.56M |
| Dyne Therapeutics, Inc.(DYN) | 3,064,000 | 3,249,708 | +185,708 | $38.76M | $63.56M | 1.56% | +$24.80M |
| Cytokinetics, Incorporated(CYTK) | 1,196,868 | 992,766 | -204,102 | $65.78M | $63.08M | 1.54% | -$2.70M |
| Alphabet Inc.CL A(GOOG) | 230,681 | 196,420 | -34,261 | $56.08M | $61.48M | 1.51% | +$5.40M |
| Microsoft Corporation(MSFT) | 87,245 | 118,337 | +31,092 | $45.19M | $57.23M | 1.40% | +$12.04M |
| Ironwood Pharmaceuticals, Inc.CL A(IRWD) | 16,150,000 | 16,025,000 | -125,000 | $21.16M | $54.00M | 1.32% | +$32.85M |
| Kura Oncology, Inc.(KURA) | 4,672,000 | 4,936,000 | +264,000 | $41.35M | $51.29M | 1.26% | +$9.94M |
| e.l.f. Beauty, Inc.(ELF) | 132,965 | 657,983 | +525,018 | $17.62M | $50.03M | 1.22% | +$32.42M |
| GSK plcADR(GSK) | 0 | 1,000,000 | +1,000,000 | $0 | $49.04M | 1.20% | +$49.04M |
| argenx SEADR(ARGX) | 58,000 | 58,000 | 0 | $42.78M | $48.78M | 1.19% | +$6.00M |
| Alibaba Group Holding LimitedADS(BABA) | 156,000 | 319,100 | +163,100 | $27.88M | $46.77M | 1.15% | +$18.89M |
| Starbucks Corporation(SBUX) | 356,107 | 549,805 | +193,698 | $30.13M | $46.30M | 1.13% | +$16.17M |
| PENN Entertainment, Inc.(PENN) | 2,103,666 | 3,096,000 | +992,334 | $40.52M | $45.67M | 1.12% | +$5.15M |
| Orthofix Medical Inc.(OFIX) | 2,236,000 | 2,648,000 | +412,000 | $32.74M | $40.14M | 0.98% | +$7.41M |
| Five9, Inc.(FIVN) | 2,000,000 | 2,000,000 | 0 | $48.40M | $40.10M | 0.98% | -$8.30M |
| Disc Medicine, Inc.(IRON) | 436,000 | 499,391 | +63,391 | $28.81M | $39.66M | 0.97% | +$10.85M |
| Immunocore Holdings plcADS(IMCR) | 824,000 | 1,098,000 | +274,000 | $29.94M | $38.11M | 0.93% | +$8.18M |
| Thermo Fisher Scientific Inc.(TMO) | 55,016 | 62,838 | +7,822 | $26.68M | $36.41M | 0.89% | +$9.73M |
| SentinelOne, Inc.CL A(S) | 1,111,200 | 2,422,219 | +1,311,019 | $19.57M | $36.33M | 0.89% | +$16.77M |
| Avanos Med Inc | 2,500,000 | 3,200,000 | +700,000 | $28.90M | $35.94M | 0.88% | +$7.04M |
| Rigel Pharmaceuticals, Inc.(RIGL) | 724,000 | 836,000 | +112,000 | $20.51M | $35.81M | 0.88% | +$15.29M |
| Autolus Therapeutics plcADS(AUTL) | 15,600,000 | 17,500,000 | +1,900,000 | $25.43M | $34.83M | 0.85% | +$9.40M |
| Intuitive Surgical, Inc.(ISRG) | 41,000 | 61,073 | +20,073 | $18.34M | $34.59M | 0.85% | +$16.25M |
| Datadog, Inc.CL A(DDOG) | 202,061 | 244,537 | +42,476 | $28.77M | $33.25M | 0.81% | +$4.48M |
| Vera Therapeutics, Inc.CL A(VERA) | 536,000 | 653,796 | +117,796 | $15.58M | $33.11M | 0.81% | +$17.53M |
| SanofiADR(SNY) | 612,000 | 676,000 | +64,000 | $28.89M | $32.76M | 0.80% | +$3.87M |
| GitLab Inc.CL A(GTLB) | 376,858 | 858,925 | +482,067 | $16.99M | $32.24M | 0.79% | +$15.25M |
| Axogen, Inc.(AXGN) | 1,200,000 | 936,000 | -264,000 | $21.41M | $30.64M | 0.75% | +$9.23M |
| Alto Neuroscience, Inc.(ANRO) | 1,636,000 | 1,536,000 | -100,000 | $6.58M | $27.34M | 0.67% | +$20.76M |
| Verastem, Inc.(VSTM) | 2,096,000 | 3,536,000 | +1,440,000 | $18.51M | $27.30M | 0.67% | +$8.79M |
| HubSpot, Inc.(HUBS) | 45,018 | 68,000 | +22,982 | $21.06M | $27.29M | 0.67% | +$6.23M |
| Medtronic plcSHS(MDT) | 265,257 | 271,241 | +5,984 | $25.26M | $26.06M | 0.64% | +$792.3K |
| Grifols, S.A.ADR(GRFS) | 2,236,000 | 2,768,000 | +532,000 | $22.27M | $25.88M | 0.63% | +$3.61M |
| Nektar Therapeutics(NKTR) | 268,000 | 596,000 | +328,000 | $15.25M | $25.20M | 0.62% | +$9.95M |
| NIKE, Inc.CL B(NKE) | 79,093 | 394,709 | +315,616 | $5.52M | $25.15M | 0.62% | +$19.63M |
| UiPath, Inc.CL A(PATH) | 1,344,284 | 1,524,617 | +180,333 | $17.99M | $24.99M | 0.61% | +$7.00M |
| Mineralys Therapeutics, Inc.(MLYS) | 507,650 | 676,035 | +168,385 | $19.25M | $24.53M | 0.60% | +$5.28M |
| Danaher Corporation(DHR) | 31,558 | 107,035 | +75,477 | $6.26M | $24.50M | 0.60% | +$18.25M |
| Edwards Lifesciences Corp | 146,571 | 277,478 | +130,907 | $11.40M | $23.66M | 0.58% | +$12.26M |
| CVS Health Corporation(CVS) | 291,819 | 295,589 | +3,770 | $22.00M | $23.46M | 0.57% | +$1.46M |
| Uber Technologies, Inc.(UBER) | 120,581 | 282,734 | +162,153 | $11.81M | $23.10M | 0.57% | +$11.29M |
| Bicycle Therapeutics PlcADS | 2,978,000 | 3,236,000 | +258,000 | $23.05M | $22.91M | 0.56% | -$138.8K |
| Nebius Group N.V.CL A(NBIS) | 213,280 | 267,421 | +54,141 | $23.94M | $22.38M | 0.55% | -$1.56M |
| AngioDynamics, Inc.(ANGO) | 1,636,000 | 1,700,000 | +64,000 | $18.27M | $21.83M | 0.53% | +$3.55M |
| DexCom, Inc.(DXCM) | 0 | 323,052 | +323,052 | $0 | $21.44M | 0.52% | +$21.44M |
| Arvinas, Inc.(ARVN) | 1,200,000 | 1,800,000 | +600,000 | $10.22M | $21.35M | 0.52% | +$11.12M |
| Wynn Resorts, Limited(WYNN) | 116,944 | 176,190 | +59,246 | $15.00M | $21.20M | 0.52% | +$6.20M |
| MongoDB, Inc.CL A(MDB) | 112,399 | 49,144 | -63,255 | $34.89M | $20.63M | 0.50% | -$14.26M |
| Energizer Holdings, Inc.(ENR) | 0 | 1,036,000 | +1,036,000 | $0 | $20.61M | 0.50% | +$20.61M |
| RH(RH) | 90,685 | 115,000 | +24,315 | $18.42M | $20.60M | 0.50% | +$2.18M |
| Workday, Inc.CL A(WDAY) | 60,892 | 93,893 | +33,001 | $14.66M | $20.17M | 0.49% | +$5.51M |
| Bristol-Myers Squibb Company(BMY) | 649,733 | 372,466 | -277,267 | $29.30M | $20.09M | 0.49% | -$9.21M |
| Ross Stores, Inc.(ROST) | 111,138 | 111,034 | -104 | $16.94M | $20.00M | 0.49% | +$3.07M |
| Harmony Biosciences Holdings, Inc.(HRMY) | 0 | 500,000 | +500,000 | $0 | $18.71M | 0.46% | +$18.71M |
| Humana Inc.(HUM) | 51,359 | 71,697 | +20,338 | $13.36M | $18.36M | 0.45% | +$5.00M |
| Reddit, Inc.CL A(RDDT) | 49,100 | 76,600 | +27,500 | $11.29M | $17.61M | 0.43% | +$6.32M |
| Live Nation Entertainment, Inc.(LYV) | 0 | 120,938 | +120,938 | $0 | $17.23M | 0.42% | +$17.23M |
| Novo Nordisk A/SADR(NVO) | 736,000 | 336,000 | -400,000 | $40.84M | $17.10M | 0.42% | -$23.74M |
| Crocs, Inc.(CROX) | 33,480 | 190,350 | +156,870 | $2.80M | $16.28M | 0.40% | +$13.48M |
| Klarna Group plcSHS(KLAR) | 0 | 549,680 | +549,680 | $0 | $15.89M | 0.39% | +$15.89M |
| Voyager Therapeutics, Inc.(VYGR) | 4,200,000 | 4,000,000 | -200,000 | $19.61M | $15.72M | 0.38% | -$3.89M |
| Treace Medical Concepts, Inc.(TMCI) | 6,316,000 | 6,364,000 | +48,000 | $42.38M | $15.59M | 0.38% | -$26.79M |
| Lennar CorporationCL A(LEN) | 78,549 | 151,295 | +72,746 | $9.90M | $15.55M | 0.38% | +$5.65M |
| Taiwan Semiconductor Manufacturing Company LimitedADS(TSM) | 56,700 | 50,000 | -6,700 | $15.84M | $15.19M | 0.37% | -$641.2K |
| AppLovin CorporationCL A(APP) | 19,520 | 22,262 | +2,742 | $14.03M | $15.00M | 0.37% | +$974.7K |
| Bill Holdings Inc | 119,198 | 271,389 | +152,191 | $6.31M | $14.80M | 0.36% | +$8.49M |
| Solid Biosciences Inc | 936,000 | 2,612,000 | +1,676,000 | $5.78M | $14.73M | 0.36% | +$8.96M |
| Dynatrace, Inc.(DT) | 400,000 | 336,000 | -64,000 | $19.38M | $14.56M | 0.36% | -$4.82M |
| 4d Molecular Therapeutics In | 1,096,000 | 1,936,000 | +840,000 | $9.52M | $14.52M | 0.36% | +$5.00M |
| Prothena Corp PlcSHS SHS | 1,824,000 | 1,500,000 | -324,000 | $17.80M | $14.32M | 0.35% | -$3.48M |
| Kalvista Pharmaceuticals Inc | 0 | 800,000 | +800,000 | $0 | $12.92M | 0.32% | +$12.92M |
| BridgeBio Oncology Therapeutics, Inc.(BBOT) | 412,000 | 1,000,000 | +588,000 | $4.77M | $12.52M | 0.31% | +$7.75M |
| Centessa Pharmaceuticals PlcADS | 378,000 | 500,000 | +122,000 | $9.17M | $12.51M | 0.31% | +$3.34M |
| NeuroPace, Inc.(NPCE) | 1,298,000 | 792,000 | -506,000 | $13.38M | $12.23M | 0.30% | -$1.15M |
| NVIDIA Corporation(NVDA) | 76,944 | 63,955 | -12,989 | $14.36M | $11.93M | 0.29% | -$2.43M |
| Align Technology Inc | 0 | 76,104 | +76,104 | $0 | $11.88M | 0.29% | +$11.88M |
| Nuvation Bio Inc.CL A(NUVB) | 2,296,000 | 1,263,737 | -1,032,263 | $8.50M | $11.32M | 0.28% | +$2.83M |
| Boston Scientific Corporation(BSX) | 80,223 | 114,025 | +33,802 | $7.83M | $10.87M | 0.27% | +$3.04M |
| The Simply Good Foods Company(SMPL) | 0 | 536,000 | +536,000 | $0 | $10.76M | 0.26% | +$10.76M |
| Intellia Therapeutics, Inc.(NTLA) | 672,000 | 1,156,000 | +484,000 | $11.61M | $10.39M | 0.25% | -$1.21M |
| MacroGenics, Inc.(MGNX) | 5,960,000 | 6,324,000 | +364,000 | $10.01M | $10.18M | 0.25% | +$168.8K |
| Advanced Micro Devices, Inc.(AMD) | 0 | 46,703 | +46,703 | $0 | $10.00M | 0.24% | +$10.00M |
| Cencora Inc | 7,033 | 28,000 | +20,967 | $2.20M | $9.46M | 0.23% | +$7.26M |
| McKesson Corporation(MCK) | 5,853 | 11,363 | +5,510 | $4.52M | $9.32M | 0.23% | +$4.80M |
| Verrica Pharmaceuticals Inc.(VRCA) | 639,193 | 1,118,925 | +479,732 | $2.75M | $9.30M | 0.23% | +$6.54M |
| Scholar Rock Holding Corporation(SRRK) | 0 | 200,000 | +200,000 | $0 | $8.81M | 0.22% | +$8.81M |
| Zeta Global Holdings Corp.CL A(ZETA) | 312,089 | 428,229 | +116,140 | $6.20M | $8.71M | 0.21% | +$2.51M |