Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| ERASCA INC(ERAS) | 17,857,083 | 16,382,812 | -1,474,271 | 66,428 | 265,074 | 9.89% | +198,646 |
| DAMORA THERAPEUTICS INC(DMRA) | 0 | 3,603,595 | +3,603,595 | 0 | 93,333 | 3.48% | +93,333 |
| ORUKA THERAPEUTICS INC(ORKA) | 4,148,428 | 4,148,428 | 0 | 125,739 | 203,480 | 7.60% | +77,742 |
| APOGEE THERAPEUTICS INC(APGE) | 8,493,321 | 8,493,321 | 0 | 641,076 | 714,883 | 26.68% | +73,807 |
| SPYRE THERAPEUTICS INC(SYRE) | 3,685,448 | 3,685,448 | 0 | 120,735 | 185,894 | 6.94% | +65,159 |
| DIANTHUS THERAPEUTICS INC(DNTH) | 1,000,000 | 1,180,000 | +180,000 | 41,210 | 99,026 | 3.70% | +57,816 |
| RELMADA THERAPEUTICS INC(RLMD) | 0 | 4,843,380 | +4,843,380 | 0 | 33,710 | 1.26% | +33,710 |
| VOR BIOPHARMA INC(VOR) | 1,943,766 | 3,041,719 | +1,097,953 | 25,424 | 54,264 | 2.03% | +28,840 |
| TENAX THERAPEUTICS INC(TENX) | 0 | 1,675,262 | +1,675,262 | 0 | 26,787 | 1.00% | +26,787 |
| ADLAI NORTYE LTD(ANL) | 0 | 3,212,731 | +3,212,731 | 0 | 22,232 | 0.83% | +22,232 |
| KALVISTA PHARMACEUTICALS INC | 6,728,985 | 6,474,485 | -254,500 | 108,673 | 130,331 | 4.86% | +21,658 |
| CENTURY THERAPEUTICS INC(IPSC) | 0 | 8,695,652 | +8,695,652 | 0 | 19,652 | 0.73% | +19,652 |
| ENLIVEN THERAPEUTICS INC | 3,226,331 | 1,726,331 | -1,500,000 | 49,685 | 67,672 | 2.53% | +17,987 |
| CRESCENT BIOPHARMA INC.(CBIO) | 2,133,576 | 2,133,576 | 0 | 25,304 | 39,194 | 1.46% | +13,890 |
| KORRO BIO INC(KRRO) | 0 | 1,009,500 | +1,009,500 | 0 | 11,428 | 0.43% | +11,428 |
| ALTO NEUROSCIENCE INC(ANRO) | 0 | 500,000 | +500,000 | 0 | 11,240 | 0.42% | +11,240 |
| ZURA BIO LTD(ZURA) | 5,345,115 | 6,434,990 | +1,089,875 | 28,008 | 38,288 | 1.43% | +10,280 |
| ORIC PHARMACEUTICALS INC(ORIC) | 5,676,230 | 4,319,765 | -1,356,465 | 46,432 | 54,731 | 2.04% | +8,300 |
| COGENT BIOSCIENCES INC(COGT) | 2,000,000 | 2,000,000 | 0 | 71,040 | 76,980 | 2.87% | +5,940 |
| CULLINAN THERAPEUTICS INC(CGEM) | 1,379,965 | 1,379,965 | 0 | 14,283 | 19,609 | 0.73% | +5,327 |
| SURROZEN INC(SRZN) | 632,931 | 632,931 | 0 | 14,304 | 18,437 | 0.69% | +4,133 |
| ARTIVA BIOTHERAPEUTICS INC(ARTV) | 1,609,569 | 1,609,569 | 0 | 6,905 | 10,366 | 0.39% | +3,461 |
| X4 PHARMACEUTICALS INC(XFOR) | 0 | 330,525 | +330,525 | 0 | 1,365 | 0.05% | +1,365 |
| CASI PHARMACEUTICALS INC(CASIF) | 987,259 | 0 | -987,259 | 839 | 0 | — | -839 |
| OCULAR THERAPEUTIX INC(OCUL) | 7,315,547 | 10,346,926 | +3,031,379 | 88,811 | 87,638 | 3.27% | -1,172 |
| DYNE THERAPEUTICS INC(DYN) | 2,173,913 | 2,173,913 | 0 | 42,522 | 39,413 | 1.47% | -3,109 |
| JADE BIOSCIENCES INC | 3,220,364 | 3,220,364 | 0 | 49,690 | 45,246 | 1.69% | -4,444 |
| SEPTERNA INC(SEPN) | 610,808 | 506,056 | -104,752 | 17,029 | 12,161 | 0.45% | -4,869 |
| SAVARA INC(SVRA) | 13,740,375 | 13,740,375 | 0 | 82,854 | 75,022 | 2.80% | -7,832 |
| ENGENE HOLDINGS INC COM | 4,771,414 | 4,771,414 | 0 | 43,086 | 32,493 | 1.21% | -10,593 |
| CYBIN INC(HELP) | 3,840,250 | 3,851,654 | +11,404 | 31,413 | 18,488 | 0.69% | -12,925 |
| MAZE THERAPEUTICS INC(MAZE) | 1,548,569 | 1,602,034 | +53,465 | 64,157 | 47,821 | 1.78% | -16,336 |
| CYTOMX THERAPEUTICS INC(CTMX) | 15,561,500 | 9,982,124 | -5,579,376 | 66,292 | 46,916 | 1.75% | -19,376 |
| UPSTREAM BIO INC(UPB) | 1,169,298 | 0 | -1,169,298 | 31,746 | 0 | — | -31,746 |
| VIRIDIAN THERAPEUTICS INC(VRDN) | 3,882,709 | 3,882,709 | 0 | 120,830 | 75,946 | 2.83% | -44,884 |