Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2024 ▲▼ | Q4 2024 ▲▼ | Change ▲▼ | Q3 2024 ▲▼ | Q4 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Apogee Therapeutics Inc | 8,493,321 | 8,493,321 | 0 | $498.90M | $384.75M | 26.40% | -$114.15M |
| Ocular Therapeutix, Inc.(OCUL) | 12,762,462 | 12,762,462 | 0 | $111.03M | $108.99M | 7.48% | -$2.04M |
| Enliven Therapeutics Inc | 4,026,331 | 4,026,331 | 0 | $102.83M | $90.59M | 6.22% | -$12.24M |
| Praxis Precision Medicines, Inc.(PRAX) | 706,131 | 989,985 | +283,854 | $40.63M | $76.19M | 5.23% | +$35.56M |
| Viridian Therapeutics, Inc.(VRDN) | 3,882,709 | 3,882,709 | 0 | $88.33M | $74.43M | 5.11% | -$13.90M |
| Oruka Therapeutics, Inc.(ORKA) | 3,085,620 | 3,285,620 | +200,000 | $75.63M | $63.71M | 4.37% | -$11.92M |
| Spyre Therapeutics, Inc.(SYRE) | 2,685,448 | 2,685,448 | 0 | $78.98M | $62.52M | 4.29% | -$16.46M |
| Pharvaris N V COM | 3,395,606 | 3,220,130 | -175,476 | $62.89M | $61.73M | 4.24% | -$1.16M |
| Kalvista Pharmaceuticals Inc | 6,249,731 | 6,249,731 | 0 | $72.37M | $52.94M | 3.63% | -$19.44M |
| Dyne Therapeutics, Inc.(DYN) | 2,173,913 | 2,173,913 | 0 | $78.09M | $51.22M | 3.51% | -$26.87M |
| Cogent Biosciences, Inc.(COGT) | 5,684,167 | 5,684,411 | +244 | $61.39M | $44.34M | 3.04% | -$17.05M |
| Erasca, Inc.(ERAS) | 16,216,216 | 16,216,216 | 0 | $44.27M | $40.70M | 2.79% | -$3.57M |
| Dianthus Therapeutics, Inc.(DNTH) | 1,744,373 | 1,744,373 | 0 | $47.76M | $38.03M | 2.61% | -$9.73M |
| Upstream Bio, Inc.(UPB) | 0 | 2,295,319 | +2,295,319 | $0 | $37.74M | 2.59% | +$37.74M |
| ORIC Pharmaceuticals, Inc.(ORIC) | 4,394,527 | 4,394,527 | 0 | $45.04M | $35.46M | 2.43% | -$9.58M |
| Engene Holdings Inc COM | 3,565,841 | 5,046,414 | +1,480,573 | $23.53M | $33.56M | 2.30% | +$10.02M |
| Merus N V | 907,963 | 592,411 | -315,552 | $45.36M | $24.91M | 1.71% | -$20.45M |
| Astria Therapeutics Inc | 3,458,645 | 2,457,348 | -1,001,297 | $38.08M | $21.97M | 1.51% | -$16.11M |
| Cidara Therapeutics Inc | 0 | 765,723 | +765,723 | $0 | $20.58M | 1.41% | +$20.58M |
| Cullinan Therapeutics, Inc.(CGEM) | 1,379,965 | 1,379,965 | 0 | $23.10M | $16.81M | 1.15% | -$6.29M |
| 4d Molecular Therapeutics In | 4,400,000 | 2,952,371 | -1,447,629 | $47.56M | $16.44M | 1.13% | -$31.12M |
| Artiva Biotherapeutics, Inc.(ARTV) | 1,609,569 | 1,609,569 | 0 | $24.87M | $16.22M | 1.11% | -$8.64M |
| Mersana Therapeutics Inc | 11,328,000 | 10,257,790 | -1,070,210 | $21.41M | $14.67M | 1.01% | -$6.74M |
| ABIVAX Société AnonymeADS(ABVX) | 1,345,780 | 1,345,780 | 0 | $15.50M | $9.85M | 0.68% | -$5.65M |
| Aquestive Therapeutics Inc | 5,555,555 | 2,629,786 | -2,925,769 | $27.67M | $9.36M | 0.64% | -$18.30M |
| Applied Therapeutics Inc | 9,825,000 | 9,990,591 | +165,591 | $83.51M | $8.55M | 0.59% | -$74.96M |
| Perceptive Cap Solutions CorCL A CL A ORD SHS | 750,000 | 750,000 | 0 | $7.51M | $7.63M | 0.52% | +$120.0K |
| Terns Pharmaceuticals Inc | 3,410,058 | 1,077,090 | -2,332,968 | $28.44M | $5.97M | 0.41% | -$22.47M |
| Taysha Gene Therapies, Inc.(TSHA) | 9,000,000 | 3,225,180 | -5,774,820 | $18.09M | $5.58M | 0.38% | -$12.51M |
| Trevi Therapeutics, Inc.(TRVI) | 3,422,656 | 1,266,457 | -2,156,199 | $11.43M | $5.22M | 0.36% | -$6.21M |
| Zura Bio LimitedCL A(ZURA) | 2,023,166 | 2,023,166 | 0 | $8.21M | $5.06M | 0.35% | -$3.16M |
| Century Therapeutics, Inc.(IPSC) | 5,389,259 | 3,957,186 | -1,432,073 | $9.22M | $4.00M | 0.27% | -$5.22M |
| CASI Pharmaceuticals, Inc.(CASIF) | 987,259 | 987,259 | 0 | $6.08M | $2.79M | 0.19% | -$3.29M |
| Tenaya Therapeutics, Inc.(TNYA) | 1,555,556 | 1,555,556 | 0 | $3.00M | $2.22M | 0.15% | -$777.8K |
| Tenax Therapeutics, Inc.(TENX) | 208,333 | 208,333 | 0 | $720.8K | $1.29M | 0.09% | +$568.7K |
| Glycomimetics Inc | 0 | 3,000,000 | +3,000,000 | $0 | $747.0K | 0.05% | +$747.0K |
| Instil Bio, Inc.(TIL) | 33,177 | 33,177 | 0 | $2.23M | $633.3K | 0.04% | -$1.60M |
| Adverum Biotechnologies Inc | 1,467,048 | 0 | -1,467,048 | $10.30M | $0 | — | -$10.30M |
| Arvinas, Inc.(ARVN) | 454,450 | 0 | -454,450 | $11.19M | $0 | — | -$11.19M |
| Cabaletta Bio, Inc.(CABA) | 1,563,952 | 0 | -1,563,952 | $7.38M | $0 | — | -$7.38M |
| Edgewise Therapeutics, Inc.(EWTX) | 1,000,000 | 0 | -1,000,000 | $26.69M | $0 | — | -$26.69M |