Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Apogee Therapeutics Inc | 8,493,321 | 8,493,321 | 0 | $337.44M | $641.08M | 31.67% | +$303.64M |
| Oruka Therapeutics, Inc.(ORKA) | 4,148,428 | 4,148,428 | 0 | $79.77M | $125.74M | 6.21% | +$45.96M |
| Viridian Therapeutics, Inc.(VRDN) | 3,882,709 | 3,882,709 | 0 | $83.79M | $120.83M | 5.97% | +$37.04M |
| Spyre Therapeutics, Inc.(SYRE) | 2,685,448 | 3,685,448 | +1,000,000 | $45.01M | $120.74M | 5.96% | +$75.73M |
| Kalvista Pharmaceuticals Inc | 6,728,985 | 6,728,985 | 0 | $81.96M | $108.67M | 5.37% | +$26.71M |
| Ocular Therapeutix, Inc.(OCUL) | 13,161,462 | 7,315,547 | -5,845,915 | $153.86M | $88.81M | 4.39% | -$65.05M |
| Savara Inc.(SVRA) | 12,681,043 | 13,740,375 | +1,059,332 | $45.27M | $82.85M | 4.09% | +$37.58M |
| Cogent Biosciences, Inc.(COGT) | 4,000,000 | 2,000,000 | -2,000,000 | $57.44M | $71.04M | 3.51% | +$13.60M |
| Erasca, Inc.(ERAS) | 17,857,083 | 17,857,083 | 0 | $38.93M | $66.43M | 3.28% | +$27.50M |
| CytomX Therapeutics, Inc.(CTMX) | 15,561,500 | 15,561,500 | 0 | $49.64M | $66.29M | 3.27% | +$16.65M |
| Maze Therapeutics, Inc.(MAZE) | 1,230,769 | 1,548,569 | +317,800 | $31.91M | $64.16M | 3.17% | +$32.24M |
| Jade Biosciences Inc | 3,220,364 | 3,220,364 | 0 | $27.79M | $49.69M | 2.45% | +$21.90M |
| Enliven Therapeutics Inc | 3,226,331 | 3,226,331 | 0 | $66.04M | $49.69M | 2.45% | -$16.36M |
| ORIC Pharmaceuticals, Inc.(ORIC) | 6,596,885 | 5,676,230 | -920,655 | $79.16M | $46.43M | 2.29% | -$32.73M |
| Engene Holdings Inc COM | 5,046,414 | 4,771,414 | -275,000 | $34.47M | $43.09M | 2.13% | +$8.62M |
| Dyne Therapeutics, Inc.(DYN) | 2,173,913 | 2,173,913 | 0 | $27.50M | $42.52M | 2.10% | +$15.02M |
| Dianthus Therapeutics, Inc.(DNTH) | 960,803 | 1,000,000 | +39,197 | $37.81M | $41.21M | 2.04% | +$3.40M |
| Upstream Bio, Inc.(UPB) | 1,169,298 | 1,169,298 | 0 | $21.99M | $31.75M | 1.57% | +$9.75M |
| Cybin D/B/A Helus Pharma(HELP) | 0 | 3,840,250 | +3,840,250 | $0 | $31.41M | 1.55% | +$31.41M |
| Zura Bio LimitedCL A(ZURA) | 4,631,216 | 5,345,115 | +713,899 | $20.05M | $28.01M | 1.38% | +$7.96M |
| Vor Biopharma Inc.(VOR) | 499,966 | 1,943,766 | +1,443,800 | $24.36M | $25.42M | 1.26% | +$1.07M |
| Crescent Biopharma, Inc.(CBIO) | 1,387,864 | 2,133,576 | +745,712 | $16.50M | $25.30M | 1.25% | +$8.80M |
| Septerna, Inc.(SEPN) | 610,808 | 610,808 | 0 | $11.49M | $17.03M | 0.84% | +$5.54M |
| Surrozen, Inc.(SRZN) | 632,931 | 632,931 | 0 | $8.16M | $14.30M | 0.71% | +$6.15M |
| Cullinan Therapeutics, Inc.(CGEM) | 1,379,965 | 1,379,965 | 0 | $8.18M | $14.28M | 0.71% | +$6.10M |
| Artiva Biotherapeutics, Inc.(ARTV) | 1,609,569 | 1,609,569 | 0 | $4.62M | $6.91M | 0.34% | +$2.29M |
| CASI Pharmaceuticals, Inc.(CASIF) | 987,259 | 987,259 | 0 | $1.64M | $839.2K | 0.04% | -$799.7K |
| ABIVAX Société AnonymeADS(ABVX) | 576,729 | 0 | -576,729 | $48.96M | $0 | — | -$48.96M |
| Astria Therapeutics Inc | 2,457,348 | 0 | -2,457,348 | $17.89M | $0 | — | -$17.89M |
| Cidara Therapeutics Inc | 946,788 | 0 | -946,788 | $90.66M | $0 | — | -$90.66M |
| Metsera Inc | 3,750,662 | 0 | -3,750,662 | $196.27M | $0 | — | -$196.27M |
| Perceptive Cap Solutions CorCL A CL A ORD SHS | 750,000 | 0 | -750,000 | $7.95M | $0 | — | -$7.95M |
| Pharvaris N V COM | 674,599 | 0 | -674,599 | $16.83M | $0 | — | -$16.83M |
| Tenax Therapeutics, Inc.(TENX) | 437,708 | 0 | -437,708 | $3.33M | $0 | — | -$3.33M |