Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q1 2026 ▲▼ | Q2 2026 ▲▼ | Change ▲▼ | Q1 2026 ▲▼ | Q2 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Natera Inc(NTRA) | 1,550,280 | 1,550,280 | 0 | 310,040 | 420,824 | 21.76% | +110,783 |
| Genmab A/S(GMAB) | 752,261 | 4,045,215 | +3,292,954 | 20,183 | 111,122 | 5.74% | +90,939 |
| Seaport Therapeutics Inc | 0 | 3,564,871 | +3,564,871 | 0 | 77,429 | 4.00% | +77,429 |
| Gilead Sciences Inc(GILD) | 0 | 343,100 | +343,100 | 0 | 43,347 | 2.24% | +43,347 |
| Nektar Therapeutics(NKTR) | 0 | 471,763 | +471,763 | 0 | 32,934 | 1.70% | +32,934 |
| Arrivent BioPharma Inc(AVBP) | 1,696,752 | 1,696,752 | 0 | 39,144 | 58,945 | 3.05% | +19,801 |
| Rapport Therapeutics Inc(RAPP) | 1,904,408 | 1,904,408 | 0 | 59,589 | 79,357 | 4.10% | +19,768 |
| Anaptysbio Inc | 248,253 | 493,536 | +245,283 | 13,768 | 33,314 | 1.72% | +19,546 |
| BioAge Labs Inc | 2,293,788 | 2,293,788 | 0 | 40,118 | 56,221 | 2.91% | +16,102 |
| Intuitive Surgical Inc(Call) | 0 | 40,000 | +40,000 | 0 | 15,907 | — | +15,907 |
| Globus Med Inc(GMED)(Call) | 0 | 200,000 | +200,000 | 0 | 15,802 | — | +15,802 |
| Veradermics Inc(MANE) | 73,315 | 148,993 | +75,678 | 4,630 | 18,317 | 0.95% | +13,687 |
| Nurix Therapeutics Inc(NRIX) | 0 | 524,098 | +524,098 | 0 | 12,715 | 0.66% | +12,715 |
| Design Therapeutics Inc(DSGN) | 0 | 865,135 | +865,135 | 0 | 12,519 | 0.65% | +12,519 |
| First Tracks Biotherapeutics | 0 | 565,199 | +565,199 | 0 | 11,372 | 0.59% | +11,372 |
| Abbott Laboratories | 0 | 122,998 | +122,998 | 0 | 11,161 | 0.58% | +11,161 |
| Ultragenyx Pharmaceutical In(RARE)(Call) | 350,000 | 500,000 | +150,000 | 7,333 | 16,695 | — | +9,363 |
| Arcus Biosciences Inc(RCUS) | 923,086 | 945,690 | +22,604 | 19,939 | 29,156 | 1.51% | +9,217 |
| Vera Therapeutics Inc(VERA) | 2,793,987 | 2,793,987 | 0 | 112,402 | 119,890 | 6.20% | +7,488 |
| Pharvaris N V COM | 818,328 | 881,299 | +62,971 | 23,118 | 30,475 | 1.58% | +7,358 |
| Tenax Therapeutics Inc | 0 | 500,039 | +500,039 | 0 | 7,276 | 0.38% | +7,276 |
| Dyne Therapeutics Inc(DYN) | 1,633,897 | 1,658,384 | +24,487 | 29,623 | 36,833 | 1.90% | +7,210 |
| Sionna Therapeutics Inc | 0 | 144,432 | +144,432 | 0 | 6,354 | 0.33% | +6,354 |
| Rhythm Pharmaceuticals Inc(RYTM) | 450,096 | 408,027 | -42,069 | 39,145 | 45,303 | 2.34% | +6,158 |
| Disc Medicine Inc(IRON) | 78,320 | 146,239 | +67,919 | 5,008 | 10,696 | 0.55% | +5,688 |
| Definium Therapeutics Inc(DFTX) | 344,166 | 255,903 | -88,263 | 6,505 | 12,038 | 0.62% | +5,533 |
| Absci Corporation | 0 | 337,400 | +337,400 | 0 | 3,910 | 0.20% | +3,910 |
| Axsome Therapeutics Inc.(AXSM) | 212,747 | 160,429 | -52,318 | 35,958 | 39,268 | 2.03% | +3,310 |
| Edgewise Therapeutics Inc(EWTX) | 386,498 | 380,923 | -5,575 | 12,175 | 15,477 | 0.80% | +3,302 |
| Exelixis Inc(EXEL)(Put) | 251,500 | 254,200 | +2,700 | 10,787 | 13,831 | — | +3,044 |
| Praxis Precision Medicines I(PRAX) | 0 | 6,440 | +6,440 | 0 | 2,156 | 0.11% | +2,156 |
| Immatics N.V(IMTX) | 3,630,454 | 3,669,346 | +38,892 | 35,724 | 37,170 | 1.92% | +1,447 |
| Inhibrx Biosciences Inc(INBX) | 406,029 | 303,103 | -102,926 | 27,297 | 28,719 | 1.48% | +1,422 |
| Sagimet Biosciences Inc | 0 | 166,667 | +166,667 | 0 | 1,288 | 0.07% | +1,288 |
| Aktis Oncology Inc(AKTS) | 0 | 32,436 | +32,436 | 0 | 1,045 | 0.05% | +1,045 |
| Onkure Therapeutics Inc | 141,700 | 321,692 | +179,992 | 587 | 1,467 | 0.08% | +880 |
| Jade Biosciences Inc | 107,391 | 107,391 | 0 | 1,509 | 2,386 | 0.12% | +877 |
| Mirum Pharmaceuticals Inc(MIRM) | 27,591 | 27,591 | 0 | 2,549 | 3,230 | 0.17% | +681 |
| Septerna Inc(SEPN) | 47,506 | 47,506 | 0 | 1,142 | 1,591 | 0.08% | +449 |
| Savara Inc(SVRA) | 364,763 | 364,763 | 0 | 1,992 | 2,247 | 0.12% | +255 |
| Heartflow Inc(HTFL) | 0 | 5,079 | +5,079 | 0 | 149 | 0.01% | +149 |
| ImageneBio Inc | 31,884 | 31,884 | 0 | 159 | 188 | 0.01% | +29 |
| Bolt Biotherapeutics Inc | 137,721 | 137,721 | 0 | 556 | 530 | 0.03% | -26 |
| Zymeworks Inc(ZYME) | 1,610 | 0 | -1,610 | 40 | 0 | — | -40 |
| Wave Life Sciences Ltd(WVE) | 189,253 | 189,253 | 0 | 1,372 | 1,100 | 0.06% | -273 |
| Soleno Therapeutics Inc | 14,689 | 0 | -14,689 | 492 | 0 | — | -492 |
| Immunome Inc(IMNM) | 1,701,904 | 1,720,316 | +18,412 | 37,221 | 36,453 | 1.88% | -767 |
| Supernus Pharmaceuticals(SUPN) | 954,309 | 1,036,328 | +82,019 | 49,328 | 48,200 | 2.49% | -1,129 |
| Tenax Therapeutics Inc | 104,400 | 0 | -104,400 | 1,669 | 0 | — | -1,669 |
| Acadia Pharmaceuticals Inc | 78,551 | 0 | -78,551 | 1,749 | 0 | — | -1,749 |
| Establishment Labs Hldgs Inc(ESTA) | 33,930 | 0 | -33,930 | 1,927 | 0 | — | -1,927 |
| Nextcure Inc | 222,654 | 222,654 | 0 | 2,378 | 356 | 0.02% | -2,022 |
| Compass Therapeutics Inc(Call) | 500,000 | 0 | -500,000 | 2,645 | 0 | — | -2,645 |
| Vaxcyte Inc(PCVX) | 50,600 | 0 | -50,600 | 2,940 | 0 | — | -2,940 |
| IDEAYA Biosciences Inc(IDYA) | 1,131,786 | 925,119 | -206,667 | 37,711 | 34,479 | 1.78% | -3,232 |
| Harmony Biosciences Hldgs Inc(HRMY) | 152,695 | 0 | -152,695 | 4,277 | 0 | — | -4,277 |
| Cytokinetics Inc(CYTK) | 91,791 | 0 | -91,791 | 6,050 | 0 | — | -6,050 |
| Tyra Biosciences Inc(TYRA) | 204,015 | 32,267 | -171,748 | 7,814 | 1,031 | 0.05% | -6,783 |
| AxoGen Inc(AXGN) | 210,665 | 0 | -210,665 | 6,979 | 0 | — | -6,979 |
| Replimune Group Inc(REPL)(Call) | 1,015,400 | 0 | -1,015,400 | 7,768 | 0 | — | -7,768 |
| Tango Therapeutics Inc(TNGX) | 395,081 | 0 | -395,081 | 8,265 | 0 | — | -8,265 |
| Ultragenyx Pharmaceutical In(RARE) | 3,145,888 | 1,717,505 | -1,428,383 | 65,906 | 57,347 | 2.96% | -8,559 |
| Oric Pharmaceuticals Inc(ORIC) | 679,578 | 0 | -679,578 | 8,610 | 0 | — | -8,610 |
| Compass Therapeutics Inc | 2,056,161 | 0 | -2,056,161 | 10,877 | 0 | — | -10,877 |
| Roivant Sciences Ltd(ROIV) | 477,995 | 0 | -477,995 | 13,240 | 0 | — | -13,240 |
| Stryker Corporation(SYK) | 44,480 | 0 | -44,480 | 14,616 | 0 | — | -14,616 |
| Xenon Pharmaceuticals Inc(XENE) | 305,216 | 0 | -305,216 | 17,748 | 0 | — | -17,748 |
| Liquidia Corporation(LQDA)(Put) | 500,000 | 0 | -500,000 | 18,870 | 0 | — | -18,870 |
| Praxis Precision Medicines Inc(PRAX) | 63,680 | 0 | -63,680 | 20,517 | 0 | — | -20,517 |
| Pfizer Inc(PFE)(Call) | 800,000 | 0 | -800,000 | 22,464 | 0 | — | -22,464 |
| BioMarin Pharmaceutical Inc(BMRN) | 781,982 | 358,568 | -423,414 | 44,174 | 20,517 | 1.06% | -23,657 |
| Dexcom Inc(DXCM) | 393,576 | 0 | -393,576 | 24,717 | 0 | — | -24,717 |
| Jazz Pharmaceuticals PLC(JAZZ) | 598,327 | 365,341 | -232,986 | 113,114 | 88,036 | 4.55% | -25,077 |
| BridgeBio Pharma Inc(BBIO) | 409,183 | 0 | -409,183 | 30,386 | 0 | — | -30,386 |
| Axsome Therapeutics Inc.(AXSM)(Put) | 200,000 | 0 | -200,000 | 33,804 | 0 | — | -33,804 |
| Celcuity Inc(CELC)(Put) | 300,000 | 0 | -300,000 | 34,242 | 0 | — | -34,242 |
| Nektar Therapeutics(NKTR) | 509,546 | 0 | -509,546 | 36,662 | 0 | — | -36,662 |
| Alcon AG(ALC) | 729,972 | 255,824 | -474,148 | 55,003 | 17,166 | 0.89% | -37,838 |
| Insmed Inc(INSM) | 346,075 | 158,398 | -187,677 | 56,590 | 16,888 | 0.87% | -39,702 |
| Cogent Biosciences Inc(COGT) | 2,113,551 | 1,035,148 | -1,078,403 | 81,351 | 40,060 | 2.07% | -41,290 |
| Celcuity Inc(CELC) | 366,175 | 0 | -366,175 | 41,795 | 0 | — | -41,795 |
| Biogen Inc(BIIB) | 229,521 | 0 | -229,521 | 42,078 | 0 | — | -42,078 |
| United Therapeutics Corp(UTHR)(Put) | 80,300 | 0 | -80,300 | 47,616 | 0 | — | -47,616 |
| United Therapeutics Corp Del(UTHR) | 160,070 | 76,489 | -83,581 | 94,918 | 41,444 | 2.14% | -53,474 |
| Bristol-Myers Squibb Co(BMY) | 1,988,721 | 876,970 | -1,111,751 | 120,616 | 50,531 | 2.61% | -70,085 |
| iShares TR(Put) | 475,000 | 0 | -475,000 | 80,204 | 0 | — | -80,204 |
| Invesco QQQ TR(Put) | 150,000 | 0 | -150,000 | 86,577 | 0 | — | -86,577 |
| AstraZeneca PLC(AZN) | 456,031 | 0 | -456,031 | 89,938 | 0 | — | -89,938 |
| SPDR Series Trust(Put) ST STR SP BIOT | 1,050,000 | 0 | -1,050,000 | 134,117 | 0 | — | -134,116 |
| iShares TR(Put) | 600,000 | 0 | -600,000 | 148,800 | 0 | — | -148,800 |