Fund HoldingsSofinnova Investments, Inc.

Total Portfolio Value
$1.53B
Total Bought
$680.02M
Total Sold
$379.34M
Net Transaction
+$300.68M
Filing Period:
Securities
SharesValue ($K)
Q4 2024
Q1 2025
Change
Q4 2024
Q1 2025
Weight (%)
Change
Invesco QQQ TR(Put)0175,000+175,000082,061+82,061
iShares TR(Put)0350,000+350,000069,822+69,822
Stryker Corporation(SYK)116,005298,567+182,56241,768111,1427.26%+69,374
Medtronic PLC(MDT)0562,992+562,992050,5903.30%+50,590
Soleno Therapeutics Inc(Put)0529,300+529,300037,818+37,818
Eli Lilly & Co(LLY)14,36452,800+38,43611,08943,6082.85%+32,519
PTC Therapeutics Inc(PTCT)0579,339+579,339029,5231.93%+29,523
BridgeBio Pharma Inc(BBIO)0734,227+734,227025,3821.66%+25,382
Blueprint Medicines Corp0261,039+261,039023,1051.51%+23,105
Bristol-Myers Squibb Co(BMY)0371,497+371,497022,6581.48%+22,658
Alnylam Pharmaceuticals Inc(ALNY)110,157176,181+66,02425,92147,5723.11%+21,651
Akero Therapeutics Inc0510,020+510,020020,6461.35%+20,646
AnaptysBio Inc132,9271,160,033+1,027,1061,76021,5651.41%+19,805
Syndax Pharmaceuticals Inc(SNDX)658,6272,275,223+1,616,5968,70727,9511.83%+19,244
Supernus Pharmaceuticals Inc(SUPN)0520,678+520,678017,0521.11%+17,052
IDEAYA Biosciences Inc(IDYA)1,069,0902,622,192+1,553,10227,47642,9522.81%+15,476
Roivant Sciences Ltd(ROIV)01,279,510+1,279,510012,9100.84%+12,910
Penumbra Inc(PEN)042,936+42,936011,4820.75%+11,482
Avidity Biosciences Inc13,789379,931+366,14240111,2160.73%+10,815
Danaher Corporation(DHR)10,00058,606+48,6062,29612,0140.78%+9,719
ACADIA Pharmaceuticals Inc(Call)0500,000+500,00008,305+8,305
Arcus Biosciences Inc(RCUS)01,037,776+1,037,77608,1470.53%+8,147
Edgewise Therapeutics Inc(EWTX)(Put)0320,400+320,40007,049+7,049
Cogent Biosciences Inc(COGT)823,1602,182,121+1,358,9616,42113,0710.85%+6,650
Praxis Precision Medicines I(PRAX)0157,640+157,64005,9700.39%+5,970
Uniqure NV(QURE)0545,771+545,77105,7850.38%+5,785
Insmed Inc(INSM)256,281304,254+47,97317,69423,2121.52%+5,518
Kura Oncology Inc(KURA)0791,667+791,66705,2250.34%+5,225
Immatics N.V(IMTX)343,2061,554,304+1,211,0982,4407,0100.46%+4,570
Dexcom Inc(DXCM)290,210395,975+105,76522,57027,0411.77%+4,472
Scholar Rock Hldg Corp(SRRK)0116,117+116,11703,7330.24%+3,733
Inhibrx Biosciences Inc(INBX)527,190697,916+170,7268,1199,7640.64%+1,645
Rhythm Pharmaceuticals(RYTM)397,428446,839+49,41122,24823,6691.55%+1,421
Jazz Pharmaceuticals PLC(JAZZ)504,193510,050+5,85762,09163,3234.14%+1,231
Metsera Inc036,800+36,80001,0020.07%+1,002
Soleno Therapeutics Inc757,248484,471-272,77734,03834,6152.26%+577
Structure Therapeutics Inc20,89234,952+14,0605676050.04%+38
Enliven Therapeutics Inc34,02533,547-4787666600.04%-105
Ikena Oncology Inc382,616382,61606274900.03%-138
Vir Biotechnology Inc(VIR)114,13183,010-31,1218385380.04%-300
Bolt Biotherapeutics Inc2,754,4372,754,43701,4741,1020.07%-372
Pulmonx Corp61,3260-61,3264160-416
Aerovate Therapeutics Inc3,758,6863,758,68609,9619,4340.62%-526
Travere Therapeutics Inc(TVTX)32,6160-32,6165680-568
ICU Med Inc(ICUI)5,0000-5,0007760-776
Nextcure Inc2,671,8562,671,85602,0601,2830.08%-777
Disc Medicine Inc(IRON)22,7527,485-15,2671,4423720.02%-1,071
Becton Dickinson & Co(BDX)4,9510-4,9511,1230-1,123
Pharvaris N V
COM
560,723593,403+32,68010,7499,3160.61%-1,433
Keros Therapeutics Inc95,3750-95,3751,5100-1,510
Savara Inc(SVRA)5,471,2995,481,666+10,36716,79715,1840.99%-1,613
Erasca Inc(ERAS)1,795,8801,877,085+81,2054,5082,5720.17%-1,936
Immunome Inc(IMNM)746,824788,666+41,8427,9315,3080.35%-2,624
Exact Sciences Corp(EXK)52,0420-52,0422,9240-2,924
Edwards Lifesciences Corp40,0000-40,0002,9610-2,961
Establishment Labs Hldgs Inc(ESTA)95,30528,675-66,6304,3911,1700.08%-3,221
Edgewise Therapeutics Inc(EWTX)402,773342,218-60,55510,7547,5290.49%-3,225
Avantor Inc(AVTR)200,0000-200,0004,2140-4,214
Achieve Life Sciences Inc1,306,4820-1,306,4824,5990-4,599
BioAge Labs Inc2,304,9012,304,901013,3458,6660.57%-4,679
Y-mAbs Therapeutics Inc2,194,2782,194,278017,1819,7210.63%-7,461
Inozyme Pharma Inc4,280,3084,280,308011,8563,8950.25%-7,961
Axsome Therapeutics Inc(AXSM)(Call)100,0000-100,0008,4610-8,461
Inari Med Inc180,4560-180,4569,2120-9,212
Janux Therapeutics Inc(JANX)253,2620-253,26213,5600-13,560
Arrivent BioPharma Inc(AVBP)1,696,7521,696,752045,20131,3732.05%-13,829
Intuitive Surgical Inc37,89611,984-25,91219,7805,9350.39%-13,845
Replimune Group Inc(REPL)3,149,5222,479,939-669,58338,14124,1791.58%-13,961
Incyte Corp(INCY)524,267357,800-166,46736,21121,6651.41%-14,546
Rapport Therapeutics Inc(RAPP)1,995,5941,995,594035,40220,0161.31%-15,386
Dyne Therapeutics Inc(DYN)1,071,498716,896-354,60225,2447,4990.49%-17,746
Globus Med Inc(GMED)244,7000-244,70020,2390-20,239
Axsome Therapeutics Inc(AXSM)491,726175,317-316,40941,60520,4471.34%-21,158
Gilead Sciences Inc(GILD)774,227418,900-355,32771,51546,9383.07%-24,578
Alkermes Plc(ALKS)894,2660-894,26625,7190-25,719
Natera Inc(NTRA)1,550,2801,550,2800245,409219,22514.32%-26,184
Boston Scientific Corp(BSX)346,5710-346,57130,9560-30,956
Sarepta Therapeutics Inc(SRPT)428,771327,618-101,15352,13420,9091.37%-31,226
AstraZeneca PLC(AZN)651,3440-651,34442,6760-42,676
Vera Therapeutics Inc(VERA)2,793,9872,793,9870118,15867,1124.38%-51,046
AbbVie Inc(ABBV)359,3930-359,39363,8640-63,864
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