Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q1 2025 ▲▼ | Q2 2025 ▲▼ | Change ▲▼ | Q1 2025 ▲▼ | Q2 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Natera, Inc.(NTRA) | 1,550,280 | 1,550,280 | 0 | $219.23M | $261.90M | 17.82% | +$42.68M |
| Gilead Sciences, Inc.(GILD) | 418,900 | 1,050,308 | +631,408 | $46.94M | $116.45M | 7.92% | +$69.51M |
| Eli Lilly and Company(LLY) | 52,800 | 97,018 | +44,218 | $43.61M | $75.63M | 5.15% | +$32.02M |
| Jazz Pharmaceuticals plcSHS USD(JAZZ) | 510,050 | 694,096 | +184,046 | $63.32M | $73.66M | 5.01% | +$10.33M |
| Vera Therapeutics, Inc.CL A(VERA) | 2,793,987 | 2,793,987 | 0 | $67.11M | $65.83M | 4.48% | -$1.29M |
| AbbVie Inc.(ABBV) | 0 | 265,850 | +265,850 | $0 | $49.35M | 3.36% | +$49.35M |
| Boston Scientific Corporation(BSX) | 0 | 431,200 | +431,200 | $0 | $46.32M | 3.15% | +$46.32M |
| DexCom, Inc.(DXCM) | 395,975 | 523,694 | +127,719 | $27.04M | $45.71M | 3.11% | +$18.67M |
| IDEAYA Biosciences, Inc.(IDYA) | 2,622,192 | 2,147,795 | -474,397 | $42.95M | $45.15M | 3.07% | +$2.20M |
| BridgeBio Pharma, Inc.(BBIO) | 734,227 | 993,093 | +258,866 | $25.38M | $42.88M | 2.92% | +$17.50M |
| Intuitive Surgical, Inc.(ISRG) | 11,984 | 70,642 | +58,658 | $5.94M | $38.39M | 2.61% | +$32.45M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 446,839 | 586,010 | +139,171 | $23.67M | $37.03M | 2.52% | +$13.36M |
| ArriVent BioPharma, Inc.(AVBP) | 1,696,752 | 1,696,752 | 0 | $31.37M | $36.94M | 2.51% | +$5.57M |
| Roivant Sciences Ltd.SHS(ROIV) | 1,279,510 | 3,088,814 | +1,809,304 | $12.91M | $34.81M | 2.37% | +$21.90M |
| Soleno Therapeutics Inc | 484,471 | 415,219 | -69,252 | $34.62M | $34.79M | 2.37% | +$171.6K |
| United Therapeutics Corporation(UTHR) | 0 | 118,513 | +118,513 | $0 | $34.05M | 2.32% | +$34.05M |
| Insmed Incorporated(INSM) | 304,254 | 313,923 | +9,669 | $23.21M | $31.59M | 2.15% | +$8.38M |
| Akero Therapeutics Inc | 510,020 | 548,788 | +38,768 | $20.65M | $29.28M | 1.99% | +$8.64M |
| Supernus Pharmaceuticals, Inc.(SUPN) | 520,678 | 799,253 | +278,575 | $17.05M | $25.19M | 1.71% | +$8.14M |
| AnaptysBio Inc | 1,160,033 | 1,032,362 | -127,671 | $21.57M | $22.92M | 1.56% | +$1.35M |
| Rapport Therapeutics, Inc.(RAPP) | 1,995,594 | 1,995,594 | 0 | $20.02M | $22.69M | 1.54% | +$2.67M |
| uniQure N.V.SHS(QURE) | 545,771 | 1,558,356 | +1,012,585 | $5.79M | $21.72M | 1.48% | +$15.94M |
| Merus N V | 0 | 404,562 | +404,562 | $0 | $21.28M | 1.45% | +$21.28M |
| AstraZeneca PLCADR(AZN) | 0 | 293,661 | +293,661 | $0 | $20.52M | 1.40% | +$20.52M |
| PTC Therapeutics, Inc.(PTCT) | 579,339 | 375,939 | -203,400 | $29.52M | $18.36M | 1.25% | -$11.16M |
| Inozyme Pharma Inc | 4,280,308 | 4,280,308 | 0 | $3.90M | $17.12M | 1.16% | +$13.23M |
| Cogent Biosciences, Inc.(COGT) | 2,182,121 | 2,355,505 | +173,384 | $13.07M | $16.91M | 1.15% | +$3.84M |
| Replimune Group, Inc.(REPL) | 2,479,939 | 1,806,529 | -673,410 | $24.18M | $16.78M | 1.14% | -$7.40M |
| Avidity Biosciences Inc | 379,931 | 584,801 | +204,870 | $11.22M | $16.61M | 1.13% | +$5.39M |
| Syndax Pharmaceuticals, Inc.(SNDX) | 2,275,223 | 1,524,440 | -750,783 | $27.95M | $14.28M | 0.97% | -$13.67M |
| Cidara Therapeutics Inc | 0 | 251,031 | +251,031 | $0 | $12.23M | 0.83% | +$12.23M |
| Immatics N.V.SHS(IMTX) | 1,554,304 | 2,240,528 | +686,224 | $7.01M | $12.05M | 0.82% | +$5.04M |
| Endeavour Silver Corp.(EXK) | 0 | 208,300 | +208,300 | $0 | $11.07M | 0.75% | +$11.07M |
| Pharvaris N V COM | 593,403 | 585,532 | -7,871 | $9.32M | $10.31M | 0.70% | +$988.9K |
| Inhibrx Biosciences, Inc.(INBX) | 697,916 | 708,678 | +10,762 | $9.76M | $10.11M | 0.69% | +$349.0K |
| Arcus Biosciences, Inc.(RCUS) | 1,037,776 | 1,216,016 | +178,240 | $8.15M | $9.90M | 0.67% | +$1.75M |
| Y-mAbs Therapeutics Inc | 2,194,278 | 2,194,278 | 0 | $9.72M | $9.90M | 0.67% | +$175.5K |
| Axsome Therapeutics, Inc.(AXSM) | 175,317 | 93,610 | -81,707 | $20.45M | $9.77M | 0.66% | -$10.68M |
| BioAge Labs, Inc.(BIOA) | 2,304,901 | 2,304,901 | 0 | $8.67M | $9.52M | 0.65% | +$852.8K |
| Edgewise Therapeutics, Inc.(EWTX) | 342,218 | 716,873 | +374,655 | $7.53M | $9.40M | 0.64% | +$1.87M |
| Immunome, Inc.(IMNM) | 788,666 | 778,476 | -10,190 | $5.31M | $7.24M | 0.49% | +$1.93M |
| Dyne Therapeutics, Inc.(DYN) | 716,896 | 614,865 | -102,031 | $7.50M | $5.85M | 0.40% | -$1.65M |
| Savara Inc.(SVRA) | 5,481,666 | 2,457,352 | -3,024,314 | $15.18M | $5.60M | 0.38% | -$9.58M |
| Apogee Therapeutics Inc | 0 | 76,180 | +76,180 | $0 | $3.31M | 0.23% | +$3.31M |
| Nextcure Inc | 2,671,856 | 2,671,856 | 0 | $1.28M | $1.23M | 0.08% | -$54.2K |
| Establishment Labs Holdings Inc.(ESTA) | 28,675 | 28,120 | -555 | $1.17M | $1.20M | 0.08% | +$30.9K |
| Jade Biosciences Inc | 0 | 107,391 | +107,391 | $0 | $1.07M | 0.07% | +$1.07M |
| Metsera Inc | 36,800 | 36,191 | -609 | $1.00M | $1.03M | 0.07% | +$27.9K |
| Scholar Rock Holding Corporation(SRRK) | 116,117 | 26,440 | -89,677 | $3.73M | $936.5K | 0.06% | -$2.80M |
| Bolt Biotherapeutics Inc | 0 | 137,721 | +137,721 | $0 | $794.6K | 0.05% | +$794.6K |
| Wave Life Sciences, Inc.SHS(WVE) | 0 | 117,903 | +117,903 | $0 | $766.4K | 0.05% | +$766.4K |
| Structure Therapeutics IncADS | 34,952 | 34,353 | -599 | $605.0K | $712.5K | 0.05% | +$107.5K |
| Praxis Precision Medicines, Inc.(PRAX) | 157,640 | 15,717 | -141,923 | $5.97M | $660.9K | 0.04% | -$5.31M |
| Ikena Oncology Inc | 382,616 | 382,616 | 0 | $489.7K | $512.7K | 0.03% | +$23.0K |
| Disc Medicine, Inc.(IRON) | 7,485 | 7,312 | -173 | $371.6K | $387.2K | 0.03% | +$15.7K |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 176,181 | 0 | -176,181 | $47.57M | $0 | — | -$47.57M |
| Blueprint Medicines Corp | 261,039 | 0 | -261,039 | $23.10M | $0 | — | -$23.10M |
| Bristol-Myers Squibb Company(BMY) | 371,497 | 0 | -371,497 | $22.66M | $0 | — | -$22.66M |
| Danaher Corporation(DHR) | 58,606 | 0 | -58,606 | $12.01M | $0 | — | -$12.01M |
| Enliven Therapeutics Inc | 33,547 | 0 | -33,547 | $660.2K | $0 | — | -$660.2K |
| Erasca, Inc.(ERAS) | 1,877,085 | 0 | -1,877,085 | $2.57M | $0 | — | -$2.57M |
| Incyte Corporation(INCY) | 357,800 | 0 | -357,800 | $21.66M | $0 | — | -$21.66M |
| Kura Oncology, Inc.(KURA) | 791,667 | 0 | -791,667 | $5.23M | $0 | — | -$5.23M |
| Medtronic plcSHS(MDT) | 562,992 | 0 | -562,992 | $50.59M | $0 | — | -$50.59M |
| Penumbra, Inc.(PEN) | 42,936 | 0 | -42,936 | $11.48M | $0 | — | -$11.48M |
| Sarepta Therapeutics, Inc.(SRPT) | 327,618 | 0 | -327,618 | $20.91M | $0 | — | -$20.91M |
| Stryker Corporation(SYK) | 298,567 | 0 | -298,567 | $111.14M | $0 | — | -$111.14M |
| Vir Biotechnology, Inc.(VIR) | 83,010 | 0 | -83,010 | $537.9K | $0 | — | -$537.9K |
| Aerovate Therapeutics Inc | 3,758,686 | 0 | -3,758,686 | $9.43M | $0 | — | -$9.43M |
| Bolt Biotherapeutics Inc | 2,754,437 | 0 | -2,754,437 | $1.10M | $0 | — | -$1.10M |