Fund HoldingsSofinnova Investments, Inc.

Total Portfolio Value
$1.64B
Total Bought
$587.22M
Total Sold
$560.84M
Net Transaction
+$26.39M
Filing Period:
Securities
SharesValue ($K)
Q1 2025
Q2 2025
Change
Q1 2025
Q2 2025
Weight (%)
Change
Gilead Sciences Inc(GILD)418,9001,050,308+631,40846,938116,4487.12%+69,510
AbbVie Inc(ABBV)0265,850+265,850049,3473.02%+49,347
iShares TR(Put)0375,000+375,000047,441+47,441
Boston Scientific Corp(BSX)0431,200+431,200046,3152.83%+46,315
Natera Inc(NTRA)1,550,2801,550,2800219,225261,90416.02%+42,679
United Therapeutics Corp(UTHR)0118,513+118,513034,0552.08%+34,055
Intuitive Surgical Inc11,98470,642+58,6585,93538,3882.35%+32,452
Eli Lilly and Co(LLY)52,80097,018+44,21843,60875,6284.63%+32,020
Roivant Sciences Ltd(ROIV)1,279,5103,088,814+1,809,30412,91034,8112.13%+21,901
Merus N V0404,562+404,562021,2801.30%+21,280
AstraZeneca PLC(AZN)0293,661+293,661020,5211.26%+20,521
Dexcom Inc(DXCM)395,975523,694+127,71927,04145,7132.80%+18,672
BridgeBio Pharma Inc(BBIO)734,227993,093+258,86625,38242,8822.62%+17,500
Uniqure NV(QURE)545,7711,558,356+1,012,5855,78521,7231.33%+15,938
Summit Therapeutics Inc(SMMT)(Call)0700,000+700,000014,896+14,896
Rhythm Pharmaceuticals Inc(RYTM)(Put)0225,000+225,000014,218+14,218
Replimune Group Inc(REPL)(Put)01,500,000+1,500,000013,935+13,935
Rhythm Pharmaceuticals Inc(RYTM)446,839586,010+139,17123,66937,0302.26%+13,361
Inozyme Pharma Inc4,280,3084,280,30803,89517,1211.05%+13,226
Cidara Therapeutics Inc0251,031+251,031012,2280.75%+12,228
Roivant Sciences Ltd(ROIV)(Call)01,000,000+1,000,000011,270+11,270
Exact Sciences Corp(EXK)0208,300+208,300011,0690.68%+11,069
Jazz Pharmaceuticals PLC(JAZZ)510,050694,096+184,04663,32373,6574.50%+10,335
Akero Therapeutics Inc510,020548,788+38,76820,64629,2831.79%+8,638
Insmed Inc(INSM)304,254313,923+9,66923,21231,5931.93%+8,382
Supernus Pharmaceuticals Inc(SUPN)520,678799,253+278,57517,05225,1921.54%+8,140
Arrivent BioPharma Inc(AVBP)1,696,7521,696,752031,37336,9382.26%+5,565
Avidity Biosciences Inc379,931584,801+204,87011,21616,6081.02%+5,393
Immatics N.V(IMTX)1,554,3042,240,528+686,2247,01012,0540.74%+5,044
Cidara Therapeutics Inc(Call)0100,000+100,00004,871+4,871
Cogent Biosciences Inc(COGT)(Call)0660,000+660,00004,739+4,739
Cogent Biosciences Inc(COGT)2,182,1212,355,505+173,38413,07116,9131.03%+3,842
Apogee Therapeutics Inc(APGE)076,180+76,18003,3080.20%+3,308
Rapport Therapeutics Inc(RAPP)1,995,5941,995,594020,01622,6901.39%+2,674
IDEAYA Biosciences Inc(IDYA)2,622,1922,147,795-474,39742,95245,1472.76%+2,195
Immunome Inc(IMNM)788,666778,476-10,1905,3087,2400.44%+1,932
Edgewise Therapeutics Inc(EWTX)342,218716,873+374,6557,5299,3980.57%+1,869
Arcus Biosciences Inc(RCUS)1,037,7761,216,016+178,2408,1479,8980.61%+1,752
AnaptysBio Inc1,160,0331,032,362-127,67121,56522,9181.40%+1,353
Jade Biosciences Inc0107,391+107,39101,0730.07%+1,073
Pharvaris N V
COM
593,403585,532-7,8719,31610,3050.63%+989
BioAge Labs Inc2,304,9012,304,90108,6669,5190.58%+853
Bolt Biotherapeutics Inc0137,721+137,72107950.05%+795
Wave Life Sciences Ltd(WVE)0117,903+117,90307660.05%+766
Inhibrx Biosciences Inc(INBX)697,916708,678+10,7629,76410,1130.62%+349
Y-mAbs Therapeutics Inc2,194,2782,194,27809,7219,8960.61%+176
Soleno Therapeutics Inc484,471415,219-69,25234,61534,7872.13%+172
Structure Therapeutics Inc34,95234,353-5996057120.04%+107
Establishment Labs Hldgs Inc(ESTA)28,67528,120-5551,1701,2010.07%+31
Metsera Inc36,80036,191-6091,0021,0300.06%+28
Ikena Oncology Inc382,616382,61604905130.03%+23
Disc Medicine Inc(IRON)7,4857,312-1733723870.02%+16
Nextcure Inc2,671,8562,671,85601,2831,2290.08%-54
Vir Biotechnology Inc(VIR)83,0100-83,0105380-538
Enliven Therapeutics Inc33,5470-33,5476600-660
Bolt Biotherapeutics Inc2,754,4370-2,754,4371,1020-1,102
Vera Therapeutics Inc(VERA)2,793,9872,793,987067,11265,8264.03%-1,285
Dyne Therapeutics Inc(DYN)716,896614,865-102,0317,4995,8540.36%-1,645
Erasca Inc(ERAS)1,877,0850-1,877,0852,5720-2,572
Scholar Rock Hldg Corp(SRRK)116,11726,440-89,6773,7339370.06%-2,797
Kura Oncology Inc(KURA)791,6670-791,6675,2250-5,225
Praxis Precision Medicines Inc(PRAX)157,64015,717-141,9235,9706610.04%-5,309
Edgewise Therapeutics Inc(EWTX)(Put)320,4000-320,4007,0490-7,049
Replimune Group Inc(REPL)2,479,9391,806,529-673,41024,17916,7831.03%-7,397
ACADIA Pharmaceuticals Inc(Call)500,0000-500,0008,3050-8,305
Aerovate Therapeutics Inc3,758,6860-3,758,6869,4340-9,434
Savara Inc(SVRA)5,481,6662,457,352-3,024,31415,1845,6030.34%-9,581
Axsome Therapeutics Inc(AXSM)175,31793,610-81,70720,4479,7720.60%-10,675
PTC Therapeutics Inc(PTCT)579,339375,939-203,40029,52318,3611.12%-11,162
Penumbra Inc(PEN)42,9360-42,93611,4820-11,482
Danaher Corporation(DHR)58,6060-58,60612,0140-12,014
Syndax Pharmaceuticals Inc(SNDX)2,275,2231,524,440-750,78327,95114,2760.87%-13,675
iShares TR(Put)350,000250,000-100,00069,82253,948-15,874
Sarepta Therapeutics Inc(SRPT)327,6180-327,61820,9090-20,909
Incyte Corp(INCY)357,8000-357,80021,6650-21,665
Bristol-Myers Squibb Co(BMY)371,4970-371,49722,6580-22,658
Blueprint Medicines Corp261,0390-261,03923,1050-23,105
Soleno Therapeutics Inc(Put)529,3000-529,30037,8180-37,818
Alnylam Pharmaceuticals Inc(ALNY)176,1810-176,18147,5720-47,572
Medtronic PLC(MDT)562,9920-562,99250,5900-50,590
Invesco QQQ TR(Put)175,0000-175,00082,0610-82,061
Stryker Corporation(SYK)298,5670-298,567111,1420-111,142
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