Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q1 2025 ▲▼ | Q2 2025 ▲▼ | Change ▲▼ | Q1 2025 ▲▼ | Q2 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Gilead Sciences Inc(GILD) | 418,900 | 1,050,308 | +631,408 | 46,938 | 116,448 | 7.92% | +69,510 |
| AbbVie Inc(ABBV) | 0 | 265,850 | +265,850 | 0 | 49,347 | 3.36% | +49,347 |
| Boston Scientific Corp(BSX) | 0 | 431,200 | +431,200 | 0 | 46,315 | 3.15% | +46,315 |
| Natera Inc(NTRA) | 1,550,280 | 1,550,280 | 0 | 219,225 | 261,904 | 17.82% | +42,679 |
| United Therapeutics Corp(UTHR) | 0 | 118,513 | +118,513 | 0 | 34,055 | 2.32% | +34,055 |
| Intuitive Surgical Inc | 11,984 | 70,642 | +58,658 | 5,935 | 38,388 | 2.61% | +32,452 |
| Eli Lilly and Co(LLY) | 52,800 | 97,018 | +44,218 | 43,608 | 75,628 | 5.15% | +32,020 |
| Roivant Sciences Ltd(ROIV) | 1,279,510 | 3,088,814 | +1,809,304 | 12,910 | 34,811 | 2.37% | +21,901 |
| Merus N V | 0 | 404,562 | +404,562 | 0 | 21,280 | 1.45% | +21,280 |
| AstraZeneca PLC(AZN) | 0 | 293,661 | +293,661 | 0 | 20,521 | 1.40% | +20,521 |
| Dexcom Inc(DXCM) | 395,975 | 523,694 | +127,719 | 27,041 | 45,713 | 3.11% | +18,672 |
| BridgeBio Pharma Inc(BBIO) | 734,227 | 993,093 | +258,866 | 25,382 | 42,882 | 2.92% | +17,500 |
| Uniqure NV(QURE) | 545,771 | 1,558,356 | +1,012,585 | 5,785 | 21,723 | 1.48% | +15,938 |
| Rhythm Pharmaceuticals Inc(RYTM) | 446,839 | 586,010 | +139,171 | 23,669 | 37,030 | 2.52% | +13,361 |
| Inozyme Pharma Inc | 4,280,308 | 4,280,308 | 0 | 3,895 | 17,121 | 1.16% | +13,226 |
| Cidara Therapeutics Inc | 0 | 251,031 | +251,031 | 0 | 12,228 | 0.83% | +12,228 |
| Exact Sciences Corp(EXK) | 0 | 208,300 | +208,300 | 0 | 11,069 | 0.75% | +11,069 |
| Jazz Pharmaceuticals PLC(JAZZ) | 510,050 | 694,096 | +184,046 | 63,323 | 73,657 | 5.01% | +10,335 |
| Akero Therapeutics Inc | 510,020 | 548,788 | +38,768 | 20,646 | 29,283 | 1.99% | +8,638 |
| Insmed Inc(INSM) | 304,254 | 313,923 | +9,669 | 23,212 | 31,593 | 2.15% | +8,382 |
| Supernus Pharmaceuticals Inc(SUPN) | 520,678 | 799,253 | +278,575 | 17,052 | 25,192 | 1.71% | +8,140 |
| Arrivent BioPharma Inc(AVBP) | 1,696,752 | 1,696,752 | 0 | 31,373 | 36,938 | 2.51% | +5,565 |
| Avidity Biosciences Inc | 379,931 | 584,801 | +204,870 | 11,216 | 16,608 | 1.13% | +5,393 |
| Immatics N.V(IMTX) | 1,554,304 | 2,240,528 | +686,224 | 7,010 | 12,054 | 0.82% | +5,044 |
| Cogent Biosciences Inc(COGT) | 2,182,121 | 2,355,505 | +173,384 | 13,071 | 16,913 | 1.15% | +3,842 |
| Apogee Therapeutics Inc(APGE) | 0 | 76,180 | +76,180 | 0 | 3,308 | 0.23% | +3,308 |
| Rapport Therapeutics Inc(RAPP) | 1,995,594 | 1,995,594 | 0 | 20,016 | 22,690 | 1.54% | +2,674 |
| IDEAYA Biosciences Inc(IDYA) | 2,622,192 | 2,147,795 | -474,397 | 42,952 | 45,147 | 3.07% | +2,195 |
| Immunome Inc(IMNM) | 788,666 | 778,476 | -10,190 | 5,308 | 7,240 | 0.49% | +1,932 |
| Edgewise Therapeutics Inc(EWTX) | 342,218 | 716,873 | +374,655 | 7,529 | 9,398 | 0.64% | +1,869 |
| Arcus Biosciences Inc(RCUS) | 1,037,776 | 1,216,016 | +178,240 | 8,147 | 9,898 | 0.67% | +1,752 |
| AnaptysBio Inc | 1,160,033 | 1,032,362 | -127,671 | 21,565 | 22,918 | 1.56% | +1,353 |
| Jade Biosciences Inc | 0 | 107,391 | +107,391 | 0 | 1,073 | 0.07% | +1,073 |
| Pharvaris N V COM | 593,403 | 585,532 | -7,871 | 9,316 | 10,305 | 0.70% | +989 |
| BioAge Labs Inc(BIOA) | 2,304,901 | 2,304,901 | 0 | 8,666 | 9,519 | 0.65% | +853 |
| Bolt Biotherapeutics Inc | 0 | 137,721 | +137,721 | 0 | 795 | 0.05% | +795 |
| Wave Life Sciences Ltd(WVE) | 0 | 117,903 | +117,903 | 0 | 766 | 0.05% | +766 |
| Inhibrx Biosciences Inc(INBX) | 697,916 | 708,678 | +10,762 | 9,764 | 10,113 | 0.69% | +349 |
| Y-mAbs Therapeutics Inc | 2,194,278 | 2,194,278 | 0 | 9,721 | 9,896 | 0.67% | +176 |
| Soleno Therapeutics Inc | 484,471 | 415,219 | -69,252 | 34,615 | 34,787 | 2.37% | +172 |
| Structure Therapeutics Inc | 34,952 | 34,353 | -599 | 605 | 712 | 0.05% | +107 |
| Establishment Labs Hldgs Inc(ESTA) | 28,675 | 28,120 | -555 | 1,170 | 1,201 | 0.08% | +31 |
| Metsera Inc | 36,800 | 36,191 | -609 | 1,002 | 1,030 | 0.07% | +28 |
| Ikena Oncology Inc | 382,616 | 382,616 | 0 | 490 | 513 | 0.03% | +23 |
| Disc Medicine Inc(IRON) | 7,485 | 7,312 | -173 | 372 | 387 | 0.03% | +16 |
| Nextcure Inc | 2,671,856 | 2,671,856 | 0 | 1,283 | 1,229 | 0.08% | -54 |
| Vir Biotechnology Inc(VIR) | 83,010 | 0 | -83,010 | 538 | 0 | — | -538 |
| Enliven Therapeutics Inc | 33,547 | 0 | -33,547 | 660 | 0 | — | -660 |
| Bolt Biotherapeutics Inc | 2,754,437 | 0 | -2,754,437 | 1,102 | 0 | — | -1,102 |
| Vera Therapeutics Inc(VERA) | 2,793,987 | 2,793,987 | 0 | 67,112 | 65,826 | 4.48% | -1,285 |
| Dyne Therapeutics Inc(DYN) | 716,896 | 614,865 | -102,031 | 7,499 | 5,854 | 0.40% | -1,645 |
| Erasca Inc(ERAS) | 1,877,085 | 0 | -1,877,085 | 2,572 | 0 | — | -2,572 |
| Scholar Rock Hldg Corp(SRRK) | 116,117 | 26,440 | -89,677 | 3,733 | 937 | 0.06% | -2,797 |
| Kura Oncology Inc(KURA) | 791,667 | 0 | -791,667 | 5,225 | 0 | — | -5,225 |
| Praxis Precision Medicines Inc(PRAX) | 157,640 | 15,717 | -141,923 | 5,970 | 661 | 0.04% | -5,309 |
| Replimune Group Inc(REPL) | 2,479,939 | 1,806,529 | -673,410 | 24,179 | 16,783 | 1.14% | -7,397 |
| Aerovate Therapeutics Inc | 3,758,686 | 0 | -3,758,686 | 9,434 | 0 | — | -9,434 |
| Savara Inc(SVRA) | 5,481,666 | 2,457,352 | -3,024,314 | 15,184 | 5,603 | 0.38% | -9,581 |
| Axsome Therapeutics Inc(AXSM) | 175,317 | 93,610 | -81,707 | 20,447 | 9,772 | 0.66% | -10,675 |
| PTC Therapeutics Inc(PTCT) | 579,339 | 375,939 | -203,400 | 29,523 | 18,361 | 1.25% | -11,162 |
| Penumbra Inc(PEN) | 42,936 | 0 | -42,936 | 11,482 | 0 | — | -11,482 |
| Danaher Corporation(DHR) | 58,606 | 0 | -58,606 | 12,014 | 0 | — | -12,014 |
| Syndax Pharmaceuticals Inc(SNDX) | 2,275,223 | 1,524,440 | -750,783 | 27,951 | 14,276 | 0.97% | -13,675 |
| Sarepta Therapeutics Inc(SRPT) | 327,618 | 0 | -327,618 | 20,909 | 0 | — | -20,909 |
| Incyte Corp(INCY) | 357,800 | 0 | -357,800 | 21,665 | 0 | — | -21,665 |
| Bristol-Myers Squibb Co(BMY) | 371,497 | 0 | -371,497 | 22,658 | 0 | — | -22,658 |
| Blueprint Medicines Corp | 261,039 | 0 | -261,039 | 23,105 | 0 | — | -23,105 |
| Alnylam Pharmaceuticals Inc(ALNY) | 176,181 | 0 | -176,181 | 47,572 | 0 | — | -47,572 |
| Medtronic PLC(MDT) | 562,992 | 0 | -562,992 | 50,590 | 0 | — | -50,590 |
| Stryker Corporation(SYK) | 298,567 | 0 | -298,567 | 111,142 | 0 | — | -111,142 |