Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q2 2025 ▲▼ | Q3 2025 ▲▼ | Change ▲▼ | Q2 2025 ▲▼ | Q3 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Natera, Inc.(NTRA) | 1,550,280 | 1,550,280 | 0 | $261.90M | $249.55M | 15.31% | -$12.36M |
| Gilead Sciences, Inc.(GILD) | 1,050,308 | 1,252,312 | +202,004 | $116.45M | $139.01M | 8.53% | +$22.56M |
| Vera Therapeutics, Inc.CL A(VERA) | 2,793,987 | 2,793,987 | 0 | $65.83M | $81.19M | 4.98% | +$15.37M |
| United Therapeutics Corporation(UTHR) | 118,513 | 190,626 | +72,113 | $34.05M | $79.91M | 4.90% | +$45.86M |
| Jazz Pharmaceuticals plcSHS USD(JAZZ) | 694,096 | 588,828 | -105,268 | $73.66M | $77.61M | 4.76% | +$3.95M |
| AstraZeneca PLCADR(AZN) | 293,661 | 823,933 | +530,272 | $20.52M | $63.21M | 3.88% | +$42.69M |
| Rapport Therapeutics, Inc.(RAPP) | 1,995,594 | 1,947,579 | -48,015 | $22.69M | $57.84M | 3.55% | +$35.15M |
| Boston Scientific Corporation(BSX) | 431,200 | 569,427 | +138,227 | $46.32M | $55.59M | 3.41% | +$9.28M |
| DexCom, Inc.(DXCM) | 523,694 | 779,616 | +255,922 | $45.71M | $52.46M | 3.22% | +$6.75M |
| Intuitive Surgical, Inc.(ISRG) | 70,642 | 110,896 | +40,254 | $38.39M | $49.60M | 3.04% | +$11.21M |
| Axsome Therapeutics, Inc.(AXSM) | 93,610 | 393,499 | +299,889 | $9.77M | $47.79M | 2.93% | +$38.02M |
| Roivant Sciences Ltd.SHS(ROIV) | 3,088,814 | 3,149,270 | +60,456 | $34.81M | $47.65M | 2.92% | +$12.84M |
| Vertex Pharmaceuticals Incorporated(VRTX) | 0 | 117,875 | +117,875 | $0 | $46.16M | 2.83% | +$46.16M |
| BridgeBio Pharma, Inc.(BBIO) | 993,093 | 831,847 | -161,246 | $42.88M | $43.21M | 2.65% | +$324.4K |
| Avidity Biosciences Inc | 584,801 | 875,925 | +291,124 | $16.61M | $38.16M | 2.34% | +$21.56M |
| AbbVie Inc.(ABBV) | 265,850 | 150,966 | -114,884 | $49.35M | $34.95M | 2.14% | -$14.39M |
| ArriVent BioPharma, Inc.(AVBP) | 1,696,752 | 1,696,752 | 0 | $36.94M | $31.31M | 1.92% | -$5.63M |
| Cogent Biosciences, Inc.(COGT) | 2,355,505 | 2,127,941 | -227,564 | $16.91M | $30.56M | 1.87% | +$13.64M |
| Glaukos Corporation(GKOS) | 0 | 312,994 | +312,994 | $0 | $25.52M | 1.57% | +$25.52M |
| IDEAYA Biosciences, Inc.(IDYA) | 2,147,795 | 922,695 | -1,225,100 | $45.15M | $25.11M | 1.54% | -$20.04M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 586,010 | 246,966 | -339,044 | $37.03M | $24.94M | 1.53% | -$12.09M |
| Akero Therapeutics Inc | 548,788 | 473,625 | -75,163 | $29.28M | $22.49M | 1.38% | -$6.80M |
| Apogee Therapeutics Inc | 76,180 | 565,417 | +489,237 | $3.31M | $22.46M | 1.38% | +$19.16M |
| Endeavour Silver Corp.(EXK) | 208,300 | 365,000 | +156,700 | $11.07M | $19.97M | 1.22% | +$8.90M |
| Immatics N.V.SHS(IMTX) | 2,240,528 | 2,227,837 | -12,691 | $12.05M | $18.98M | 1.16% | +$6.93M |
| Pharvaris N V COM | 585,532 | 739,876 | +154,344 | $10.31M | $18.46M | 1.13% | +$8.15M |
| Supernus Pharmaceuticals, Inc.(SUPN) | 799,253 | 377,066 | -422,187 | $25.19M | $18.02M | 1.11% | -$7.17M |
| Arcus Biosciences, Inc.(RCUS) | 1,216,016 | 1,222,263 | +6,247 | $9.90M | $16.62M | 1.02% | +$6.72M |
| Merus N V | 404,562 | 166,729 | -237,833 | $21.28M | $15.70M | 0.96% | -$5.58M |
| Insmed Incorporated(INSM) | 313,923 | 104,339 | -209,584 | $31.59M | $15.03M | 0.92% | -$16.57M |
| Inhibrx Biosciences, Inc.(INBX) | 708,678 | 440,092 | -268,586 | $10.11M | $14.82M | 0.91% | +$4.71M |
| BioAge Labs, Inc.(BIOA) | 2,304,901 | 2,293,788 | -11,113 | $9.52M | $13.49M | 0.83% | +$3.97M |
| Celcuity Inc.(CELC) | 0 | 253,375 | +253,375 | $0 | $12.52M | 0.77% | +$12.52M |
| Dyne Therapeutics, Inc.(DYN) | 614,865 | 985,828 | +370,963 | $5.85M | $12.47M | 0.77% | +$6.62M |
| PTC Therapeutics, Inc.(PTCT) | 375,939 | 186,932 | -189,007 | $18.36M | $11.47M | 0.70% | -$6.89M |
| GE HealthCare Technologies Inc.(GEHC) | 0 | 151,085 | +151,085 | $0 | $11.35M | 0.70% | +$11.35M |
| Soleno Therapeutics Inc | 415,219 | 166,281 | -248,938 | $34.79M | $11.24M | 0.69% | -$23.55M |
| Praxis Precision Medicines, Inc.(PRAX) | 15,717 | 172,833 | +157,116 | $660.9K | $9.16M | 0.56% | +$8.50M |
| Savara Inc.(SVRA) | 2,457,352 | 2,427,724 | -29,628 | $5.60M | $8.67M | 0.53% | +$3.06M |
| Edgewise Therapeutics, Inc.(EWTX) | 716,873 | 520,240 | -196,633 | $9.40M | $8.44M | 0.52% | -$959.9K |
| uniQure N.V.SHS(QURE) | 1,558,356 | 136,862 | -1,421,494 | $21.72M | $7.99M | 0.49% | -$13.73M |
| AnaptysBio Inc | 1,032,362 | 254,268 | -778,094 | $22.92M | $7.79M | 0.48% | -$15.13M |
| Compass Therapeutics, Inc.(CMPX) | 0 | 2,028,886 | +2,028,886 | $0 | $7.10M | 0.44% | +$7.10M |
| Nektar Therapeutics(NKTR) | 0 | 118,419 | +118,419 | $0 | $6.74M | 0.41% | +$6.74M |
| Cidara Therapeutics Inc | 251,031 | 54,197 | -196,834 | $12.23M | $5.19M | 0.32% | -$7.04M |
| Immunome, Inc.(IMNM) | 778,476 | 436,051 | -342,425 | $7.24M | $5.11M | 0.31% | -$2.13M |
| Nextcure Inc | 0 | 222,654 | +222,654 | $0 | $1.30M | 0.08% | +$1.30M |
| Wave Life Sciences, Inc.SHS(WVE) | 117,903 | 170,943 | +53,040 | $766.4K | $1.25M | 0.08% | +$484.9K |
| Scholar Rock Holding Corporation(SRRK) | 26,440 | 31,410 | +4,970 | $936.5K | $1.17M | 0.07% | +$233.2K |
| Jade Biosciences Inc | 107,391 | 107,391 | 0 | $1.07M | $926.8K | 0.06% | -$146.1K |
| Disc Medicine, Inc.(IRON) | 7,312 | 13,553 | +6,241 | $387.2K | $895.6K | 0.05% | +$508.3K |
| Bolt Biotherapeutics Inc | 137,721 | 137,721 | 0 | $794.6K | $732.7K | 0.04% | -$62.0K |
| Acadia Pharmaceuticals Inc | 0 | 26,800 | +26,800 | $0 | $571.9K | 0.04% | +$571.9K |
| Establishment Labs Holdings Inc.(ESTA) | 28,120 | 10,787 | -17,333 | $1.20M | $442.2K | 0.03% | -$758.8K |
| ImageneBio, Inc.(IMA) | 0 | 31,884 | +31,884 | $0 | $259.9K | 0.02% | +$259.9K |
| Eli Lilly and Company(LLY) | 97,018 | 0 | -97,018 | $75.63M | $0 | — | -$75.63M |
| Metsera Inc | 36,191 | 0 | -36,191 | $1.03M | $0 | — | -$1.03M |
| Replimune Group, Inc.(REPL) | 1,806,529 | 0 | -1,806,529 | $16.78M | $0 | — | -$16.78M |
| Structure Therapeutics IncADS | 34,353 | 0 | -34,353 | $712.5K | $0 | — | -$712.5K |
| Syndax Pharmaceuticals, Inc.(SNDX) | 1,524,440 | 0 | -1,524,440 | $14.28M | $0 | — | -$14.28M |
| Ikena Oncology Inc | 382,616 | 0 | -382,616 | $512.7K | $0 | — | -$512.7K |
| Inozyme Pharma Inc | 4,280,308 | 0 | -4,280,308 | $17.12M | $0 | — | -$17.12M |
| Nextcure Inc | 2,671,856 | 0 | -2,671,856 | $1.23M | $0 | — | -$1.23M |
| Y-mAbs Therapeutics Inc | 2,194,278 | 0 | -2,194,278 | $9.90M | $0 | — | -$9.90M |