Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q3 2024 ▲▼ | Q4 2024 ▲▼ | Change ▲▼ | Q3 2024 ▲▼ | Q4 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Gilead Sciences Inc(GILD) | 0 | 774,227 | +774,227 | 0 | 71,515 | 5.24% | +71,515 |
| AbbVie Inc(ABBV) | 0 | 359,393 | +359,393 | 0 | 63,864 | 4.68% | +63,864 |
| Sarepta Therapeutics Inc(SRPT) | 0 | 428,771 | +428,771 | 0 | 52,134 | 3.82% | +52,134 |
| Natera Inc(NTRA) | 1,550,280 | 1,550,280 | 0 | 196,808 | 245,409 | 17.99% | +48,601 |
| Stryker Corporation(SYK) | 0 | 116,005 | +116,005 | 0 | 41,768 | 3.06% | +41,768 |
| Jazz Pharmaceuticals PLC(JAZZ) | 188,562 | 504,193 | +315,631 | 21,008 | 62,091 | 4.55% | +41,084 |
| Replimune Group Inc(REPL) | 48,138 | 3,149,522 | +3,101,384 | 528 | 38,141 | 2.80% | +37,613 |
| Alnylam Pharmaceuticals Inc(ALNY) | 0 | 110,157 | +110,157 | 0 | 25,921 | 1.90% | +25,921 |
| Alkermes Plc(ALKS) | 0 | 894,266 | +894,266 | 0 | 25,719 | 1.89% | +25,719 |
| Dexcom Inc(DXCM) | 0 | 290,210 | +290,210 | 0 | 22,570 | 1.65% | +22,570 |
| Globus Med Inc(GMED) | 0 | 244,700 | +244,700 | 0 | 20,239 | 1.48% | +20,239 |
| Intuitive Surgical Inc | 0 | 37,896 | +37,896 | 0 | 19,780 | 1.45% | +19,780 |
| Boston Scientific Corp(BSX) | 135,819 | 346,571 | +210,752 | 11,382 | 30,956 | 2.27% | +19,574 |
| Eli Lilly & Co(LLY) | 0 | 14,364 | +14,364 | 0 | 11,089 | 0.81% | +11,089 |
| Rhythm Pharmaceuticals Inc(RYTM) | 276,678 | 397,428 | +120,750 | 14,495 | 22,248 | 1.63% | +7,753 |
| Axsome Therapeutics Inc(AXSM) | 379,527 | 491,726 | +112,199 | 34,108 | 41,605 | 3.05% | +7,497 |
| Janux Therapeutics Inc(JANX) | 164,770 | 253,262 | +88,492 | 7,486 | 13,560 | 0.99% | +6,074 |
| Inari Med Inc | 90,327 | 180,456 | +90,129 | 3,725 | 9,212 | 0.68% | +5,487 |
| Arrivent BioPharma Inc(AVBP) | 1,696,752 | 1,696,752 | 0 | 39,874 | 45,201 | 3.31% | +5,328 |
| Soleno Therapeutics Inc | 586,344 | 757,248 | +170,904 | 29,605 | 34,038 | 2.49% | +4,434 |
| Avantor Inc(AVTR) | 0 | 200,000 | +200,000 | 0 | 4,214 | 0.31% | +4,214 |
| Danaher Corporation(DHR) | 0 | 10,000 | +10,000 | 0 | 2,296 | 0.17% | +2,296 |
| Aerovate Therapeutics Inc | 3,758,686 | 3,758,686 | 0 | 7,856 | 9,961 | 0.73% | +2,105 |
| AnaptysBio Inc | 0 | 132,927 | +132,927 | 0 | 1,760 | 0.13% | +1,760 |
| Keros Therapeutics Inc(KROS) | 0 | 95,375 | +95,375 | 0 | 1,510 | 0.11% | +1,510 |
| ICU Med Inc(ICUI) | 0 | 5,000 | +5,000 | 0 | 776 | 0.06% | +776 |
| Enliven Therapeutics Inc | 0 | 34,025 | +34,025 | 0 | 766 | 0.06% | +766 |
| Travere Therapeutics Inc(TVTX) | 0 | 32,616 | +32,616 | 0 | 568 | 0.04% | +568 |
| Edgewise Therapeutics Inc(EWTX) | 384,767 | 402,773 | +18,006 | 10,269 | 10,754 | 0.79% | +485 |
| Exact Sciences Corp(EXK) | 37,637 | 52,042 | +14,405 | 2,564 | 2,924 | 0.21% | +360 |
| Ikena Oncology Inc | 382,616 | 382,616 | 0 | 662 | 627 | 0.05% | -34 |
| Pulmonx Corp(LUNG) | 62,313 | 61,326 | -987 | 517 | 416 | 0.03% | -100 |
| Vir Biotechnology Inc(VIR) | 129,246 | 114,131 | -15,115 | 968 | 838 | 0.06% | -130 |
| Inhibrx Biosciences Inc(INBX) | 536,068 | 527,190 | -8,878 | 8,395 | 8,119 | 0.60% | -276 |
| Bolt Biotherapeutics Inc | 2,754,437 | 2,754,437 | 0 | 1,785 | 1,474 | 0.11% | -311 |
| Pharvaris N V COM | 600,302 | 560,723 | -39,579 | 11,118 | 10,749 | 0.79% | -369 |
| Erasca Inc(ERAS) | 1,842,668 | 1,795,880 | -46,788 | 5,030 | 4,508 | 0.33% | -523 |
| Disc Medicine Inc(IRON) | 41,352 | 22,752 | -18,600 | 2,032 | 1,442 | 0.11% | -590 |
| Immatics N.V | 366,568 | 0 | -366,568 | 852 | 0 | — | -852 |
| Astria Therapeutics Inc | 85,640 | 0 | -85,640 | 943 | 0 | — | -943 |
| Avidity Biosciences Inc | 30,472 | 13,789 | -16,683 | 1,400 | 401 | 0.03% | -999 |
| Structure Therapeutics Inc | 38,792 | 20,892 | -17,900 | 1,703 | 567 | 0.04% | -1,136 |
| Nextcure Inc | 2,671,856 | 2,671,856 | 0 | 3,660 | 2,060 | 0.15% | -1,600 |
| Perspective Therapeutics Inc(CATX) | 120,632 | 0 | -120,632 | 1,610 | 0 | — | -1,610 |
| Immunome Inc(IMNM) | 676,766 | 746,824 | +70,058 | 9,894 | 7,931 | 0.58% | -1,963 |
| Immatics N.V(IMTX) | 386,100 | 343,206 | -42,894 | 4,405 | 2,440 | 0.18% | -1,965 |
| Dyne Therapeutics Inc(DYN) | 772,070 | 1,071,498 | +299,428 | 27,733 | 25,244 | 1.85% | -2,488 |
| Becton Dickinson & Co(BDX) | 15,191 | 4,951 | -10,240 | 3,663 | 1,123 | 0.08% | -2,539 |
| Achieve Life Sciences Inc | 1,514,032 | 1,306,482 | -207,550 | 7,177 | 4,599 | 0.34% | -2,578 |
| Insmed Inc(INSM) | 286,307 | 256,281 | -30,026 | 20,900 | 17,694 | 1.30% | -3,207 |
| Establishment Labs Hldgs Inc(ESTA) | 181,476 | 95,305 | -86,171 | 7,852 | 4,391 | 0.32% | -3,462 |
| Thermo Fisher Scientific Inc(TMO) | 5,770 | 0 | -5,770 | 3,569 | 0 | — | -3,569 |
| Illumina Inc(ILMN) | 40,611 | 0 | -40,611 | 5,296 | 0 | — | -5,296 |
| Vera Therapeutics Inc(VERA) | 2,793,987 | 2,793,987 | 0 | 123,494 | 118,158 | 8.66% | -5,337 |
| Phibro Animal Health Corp(PAHC) | 238,184 | 0 | -238,184 | 5,364 | 0 | — | -5,364 |
| Rapport Therapeutics Inc(RAPP) | 1,995,594 | 1,995,594 | 0 | 40,870 | 35,402 | 2.59% | -5,468 |
| Kura Oncology Inc(KURA) | 296,884 | 0 | -296,884 | 5,801 | 0 | — | -5,801 |
| Syndax Pharmaceuticals Inc(SNDX) | 786,999 | 658,627 | -128,372 | 15,150 | 8,707 | 0.64% | -6,443 |
| Savara Inc(SVRA) | 5,662,550 | 5,471,299 | -191,251 | 24,009 | 16,797 | 1.23% | -7,212 |
| Cabaletta Bio Inc(CABA) | 1,533,883 | 0 | -1,533,883 | 7,240 | 0 | — | -7,240 |
| Marinus Pharmaceuticals Inc | 4,386,177 | 0 | -4,386,177 | 7,720 | 0 | — | -7,720 |
| TG Therapeutics Inc(TGTX) | 358,644 | 0 | -358,644 | 8,389 | 0 | — | -8,389 |
| Revolution Medicines Inc(RVMD) | 203,271 | 0 | -203,271 | 9,218 | 0 | — | -9,218 |
| Guardant Health Inc(GH) | 406,645 | 0 | -406,645 | 9,328 | 0 | — | -9,328 |
| Edwards Lifesciences Corp | 202,898 | 40,000 | -162,898 | 13,389 | 2,961 | 0.22% | -10,428 |
| Inozyme Pharma Inc | 4,280,308 | 4,280,308 | 0 | 22,386 | 11,856 | 0.87% | -10,530 |
| Incyte Corp(INCY) | 714,176 | 524,267 | -189,909 | 47,207 | 36,211 | 2.65% | -10,996 |
| Y-mAbs Therapeutics Inc | 2,194,278 | 2,194,278 | 0 | 28,855 | 17,181 | 1.26% | -11,674 |
| Cogent Biosciences Inc(COGT) | 2,265,230 | 823,160 | -1,442,070 | 24,464 | 6,421 | 0.47% | -18,044 |
| AstraZeneca PLC(AZN) | 809,406 | 651,344 | -158,062 | 63,061 | 42,676 | 3.13% | -20,385 |
| IDEAYA Biosciences Inc(IDYA) | 1,749,455 | 1,069,090 | -680,365 | 55,423 | 27,476 | 2.01% | -27,947 |
| BioAge Labs Inc(BIOA) | 2,304,901 | 2,304,901 | 0 | 47,942 | 13,345 | 0.98% | -34,597 |
| Elanco Animal Health Inc(ELAN) | 3,518,684 | 0 | -3,518,684 | 51,689 | 0 | — | -51,689 |
| Novo-Nordisk A S(NVO) | 726,329 | 0 | -726,329 | 86,484 | 0 | — | -86,484 |