Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2024 ▲▼ | Q4 2024 ▲▼ | Change ▲▼ | Q3 2024 ▲▼ | Q4 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Natera, Inc.(NTRA) | 1,550,280 | 1,550,280 | 0 | $196.81M | $245.41M | 17.99% | +$48.60M |
| Vera Therapeutics, Inc.CL A(VERA) | 2,793,987 | 2,793,987 | 0 | $123.49M | $118.16M | 8.66% | -$5.34M |
| Gilead Sciences, Inc.(GILD) | 0 | 774,227 | +774,227 | $0 | $71.52M | 5.24% | +$71.52M |
| AbbVie Inc.(ABBV) | 0 | 359,393 | +359,393 | $0 | $63.86M | 4.68% | +$63.86M |
| Jazz Pharmaceuticals plcSHS USD(JAZZ) | 188,562 | 504,193 | +315,631 | $21.01M | $62.09M | 4.55% | +$41.08M |
| Sarepta Therapeutics, Inc.(SRPT) | 0 | 428,771 | +428,771 | $0 | $52.13M | 3.82% | +$52.13M |
| ArriVent BioPharma, Inc.(AVBP) | 1,696,752 | 1,696,752 | 0 | $39.87M | $45.20M | 3.31% | +$5.33M |
| AstraZeneca PLCADR(AZN) | 809,406 | 651,344 | -158,062 | $63.06M | $42.68M | 3.13% | -$20.38M |
| Stryker Corporation(SYK) | 0 | 116,005 | +116,005 | $0 | $41.77M | 3.06% | +$41.77M |
| Axsome Therapeutics, Inc.(AXSM) | 379,527 | 491,726 | +112,199 | $34.11M | $41.60M | 3.05% | +$7.50M |
| Replimune Group, Inc.(REPL) | 48,138 | 3,149,522 | +3,101,384 | $527.6K | $38.14M | 2.80% | +$37.61M |
| Incyte Corporation(INCY) | 714,176 | 524,267 | -189,909 | $47.21M | $36.21M | 2.65% | -$11.00M |
| Rapport Therapeutics, Inc.(RAPP) | 1,995,594 | 1,995,594 | 0 | $40.87M | $35.40M | 2.59% | -$5.47M |
| Soleno Therapeutics Inc | 586,344 | 757,248 | +170,904 | $29.60M | $34.04M | 2.49% | +$4.43M |
| Boston Scientific Corporation(BSX) | 135,819 | 346,571 | +210,752 | $11.38M | $30.96M | 2.27% | +$19.57M |
| IDEAYA Biosciences, Inc.(IDYA) | 1,749,455 | 1,069,090 | -680,365 | $55.42M | $27.48M | 2.01% | -$27.95M |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 0 | 110,157 | +110,157 | $0 | $25.92M | 1.90% | +$25.92M |
| Alkermes plcSHS(ALKS) | 0 | 894,266 | +894,266 | $0 | $25.72M | 1.89% | +$25.72M |
| Dyne Therapeutics, Inc.(DYN) | 772,070 | 1,071,498 | +299,428 | $27.73M | $25.24M | 1.85% | -$2.49M |
| DexCom, Inc.(DXCM) | 0 | 290,210 | +290,210 | $0 | $22.57M | 1.65% | +$22.57M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 276,678 | 397,428 | +120,750 | $14.50M | $22.25M | 1.63% | +$7.75M |
| Globus Medical, Inc.CL A(GMED) | 0 | 244,700 | +244,700 | $0 | $20.24M | 1.48% | +$20.24M |
| Intuitive Surgical, Inc.(ISRG) | 0 | 37,896 | +37,896 | $0 | $19.78M | 1.45% | +$19.78M |
| Insmed Incorporated(INSM) | 286,307 | 256,281 | -30,026 | $20.90M | $17.69M | 1.30% | -$3.21M |
| Y-mAbs Therapeutics Inc | 2,194,278 | 2,194,278 | 0 | $28.85M | $17.18M | 1.26% | -$11.67M |
| Savara Inc.(SVRA) | 5,662,550 | 5,471,299 | -191,251 | $24.01M | $16.80M | 1.23% | -$7.21M |
| Janux Therapeutics, Inc.(JANX) | 164,770 | 253,262 | +88,492 | $7.49M | $13.56M | 0.99% | +$6.07M |
| BioAge Labs, Inc.(BIOA) | 2,304,901 | 2,304,901 | 0 | $47.94M | $13.35M | 0.98% | -$34.60M |
| Inozyme Pharma Inc | 4,280,308 | 4,280,308 | 0 | $22.39M | $11.86M | 0.87% | -$10.53M |
| Eli Lilly and Company(LLY) | 0 | 14,364 | +14,364 | $0 | $11.09M | 0.81% | +$11.09M |
| Edgewise Therapeutics, Inc.(EWTX) | 384,767 | 402,773 | +18,006 | $10.27M | $10.75M | 0.79% | +$484.6K |
| Pharvaris N V COM | 600,302 | 560,723 | -39,579 | $11.12M | $10.75M | 0.79% | -$368.5K |
| Aerovate Therapeutics Inc | 3,758,686 | 3,758,686 | 0 | $7.86M | $9.96M | 0.73% | +$2.10M |
| Inari Med Inc | 90,327 | 180,456 | +90,129 | $3.73M | $9.21M | 0.68% | +$5.49M |
| Syndax Pharmaceuticals, Inc.(SNDX) | 786,999 | 658,627 | -128,372 | $15.15M | $8.71M | 0.64% | -$6.44M |
| Inhibrx Biosciences, Inc.(INBX) | 536,068 | 527,190 | -8,878 | $8.39M | $8.12M | 0.60% | -$276.1K |
| Immunome, Inc.(IMNM) | 676,766 | 746,824 | +70,058 | $9.89M | $7.93M | 0.58% | -$1.96M |
| Cogent Biosciences, Inc.(COGT) | 2,265,230 | 823,160 | -1,442,070 | $24.46M | $6.42M | 0.47% | -$18.04M |
| Achieve Life Sciences Inc | 1,514,032 | 1,306,482 | -207,550 | $7.18M | $4.60M | 0.34% | -$2.58M |
| Erasca, Inc.(ERAS) | 1,842,668 | 1,795,880 | -46,788 | $5.03M | $4.51M | 0.33% | -$522.8K |
| Establishment Labs Holdings Inc.(ESTA) | 181,476 | 95,305 | -86,171 | $7.85M | $4.39M | 0.32% | -$3.46M |
| Avantor, Inc.(AVTR) | 0 | 200,000 | +200,000 | $0 | $4.21M | 0.31% | +$4.21M |
| Edwards Lifesciences Corp | 202,898 | 40,000 | -162,898 | $13.39M | $2.96M | 0.22% | -$10.43M |
| Endeavour Silver Corp.(EXK) | 37,637 | 52,042 | +14,405 | $2.56M | $2.92M | 0.21% | +$360.4K |
| Immatics N.V.SHS(IMTX) | 386,100 | 343,206 | -42,894 | $4.41M | $2.44M | 0.18% | -$1.97M |
| Danaher Corporation(DHR) | 0 | 10,000 | +10,000 | $0 | $2.30M | 0.17% | +$2.30M |
| Nextcure Inc | 2,671,856 | 2,671,856 | 0 | $3.66M | $2.06M | 0.15% | -$1.60M |
| AnaptysBio Inc | 0 | 132,927 | +132,927 | $0 | $1.76M | 0.13% | +$1.76M |
| Keros Therapeutics, Inc.(KROS) | 0 | 95,375 | +95,375 | $0 | $1.51M | 0.11% | +$1.51M |
| Bolt Biotherapeutics Inc | 2,754,437 | 2,754,437 | 0 | $1.78M | $1.47M | 0.11% | -$311.3K |
| Disc Medicine, Inc.(IRON) | 41,352 | 22,752 | -18,600 | $2.03M | $1.44M | 0.11% | -$589.6K |
| Becton, Dickinson and Company(BDX) | 15,191 | 4,951 | -10,240 | $3.66M | $1.12M | 0.08% | -$2.54M |
| Vir Biotechnology, Inc.(VIR) | 129,246 | 114,131 | -15,115 | $968.1K | $837.7K | 0.06% | -$130.3K |
| ICU Medical, Inc.(ICUI) | 0 | 5,000 | +5,000 | $0 | $775.9K | 0.06% | +$775.9K |
| Enliven Therapeutics Inc | 0 | 34,025 | +34,025 | $0 | $765.6K | 0.06% | +$765.6K |
| Ikena Oncology Inc | 382,616 | 382,616 | 0 | $661.9K | $627.5K | 0.05% | -$34.4K |
| Travere Therapeutics, Inc.(TVTX) | 0 | 32,616 | +32,616 | $0 | $568.2K | 0.04% | +$568.2K |
| Structure Therapeutics IncADS | 38,792 | 20,892 | -17,900 | $1.70M | $566.6K | 0.04% | -$1.14M |
| Pulmonx Corporation(LUNG) | 62,313 | 61,326 | -987 | $516.6K | $416.4K | 0.03% | -$100.2K |
| Avidity Biosciences Inc | 30,472 | 13,789 | -16,683 | $1.40M | $401.0K | 0.03% | -$998.6K |
| Astria Therapeutics Inc | 85,640 | 0 | -85,640 | $942.9K | $0 | — | -$942.9K |
| Cabaletta Bio, Inc.(CABA) | 1,533,883 | 0 | -1,533,883 | $7.24M | $0 | — | -$7.24M |
| Elanco Animal Health Incorporated(ELAN) | 3,518,684 | 0 | -3,518,684 | $51.69M | $0 | — | -$51.69M |
| Guardant Health, Inc.(GH) | 406,645 | 0 | -406,645 | $9.33M | $0 | — | -$9.33M |
| Illumina, Inc.(ILMN) | 40,611 | 0 | -40,611 | $5.30M | $0 | — | -$5.30M |
| Immatics N.VW EXP 07 01 2025 | 366,568 | 0 | -366,568 | $852.3K | $0 | — | -$852.3K |
| Kura Oncology, Inc.(KURA) | 296,884 | 0 | -296,884 | $5.80M | $0 | — | -$5.80M |
| Marinus Pharmaceuticals Inc | 4,386,177 | 0 | -4,386,177 | $7.72M | $0 | — | -$7.72M |
| Novo Nordisk A/SADR(NVO) | 726,329 | 0 | -726,329 | $86.48M | $0 | — | -$86.48M |
| Perspective Therapeutics, Inc.(CATX) | 120,632 | 0 | -120,632 | $1.61M | $0 | — | -$1.61M |
| Phibro Animal Health CorporationCL A(PAHC) | 238,184 | 0 | -238,184 | $5.36M | $0 | — | -$5.36M |
| Revolution Medicines, Inc.(RVMD) | 203,271 | 0 | -203,271 | $9.22M | $0 | — | -$9.22M |
| TG Therapeutics, Inc.(TGTX) | 358,644 | 0 | -358,644 | $8.39M | $0 | — | -$8.39M |
| Thermo Fisher Scientific Inc.(TMO) | 5,770 | 0 | -5,770 | $3.57M | $0 | — | -$3.57M |