Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q1 2026 ▲▼ | Q2 2026 ▲▼ | Change ▲▼ | Q1 2026 ▲▼ | Q2 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| United Therapeutics Corporation(UTHR) | 2,630,000 | 2,777,777 | +147,777 | $1.56B | $1.51B | 13.52% | -$54.45M |
| Ascendis Pharma A/S(ASND) | 0 | 5,111,111 | +5,111,111 | $0 | $1.36B | 12.24% | +$1.36B |
| Krystal Biotech, Inc.(KRYS) | 2,888,888 | 2,888,888 | 0 | $746.26M | $1.07B | 9.64% | +$327.46M |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 1,818,181 | 1,833,333 | +15,152 | $951.76M | $984.41M | 8.84% | +$32.64M |
| argenx SEADR(ARGX) | 1,000,000 | 1,000,000 | 0 | $730.25M | $927.77M | 8.33% | +$197.52M |
| Arrowhead Pharmaceuticals, Inc.(ARWR) | 10,699,999 | 11,355,555 | +655,556 | $670.89M | $925.59M | 8.31% | +$254.70M |
| Kymera Therapeutics, Inc.(KYMR) | 7,474,747 | 7,474,747 | 0 | $622.57M | $857.13M | 7.70% | +$234.56M |
| Revolution Medicines, Inc.(RVMD) | 2,344,444 | 2,297,000 | -47,444 | $228.00M | $430.18M | 3.86% | +$202.18M |
| Cytokinetics, Incorporated(CYTK) | 3,333,333 | 4,999,999 | +1,666,666 | $219.70M | $425.95M | 3.82% | +$206.25M |
| Celcuity Inc.(CELC) | 3,375,000 | 3,400,000 | +25,000 | $385.22M | $355.71M | 3.19% | -$29.51M |
| Structure Therapeutics IncADS | 6,555,555 | 6,555,555 | 0 | $315.98M | $351.84M | 3.16% | +$35.86M |
| Xenon Pharmaceuticals Inc.(XENE) | 5,777,777 | 5,777,777 | 0 | $335.98M | $348.75M | 3.13% | +$12.77M |
| Definium Therapeutics, Inc.(DFTX) | 5,000,000 | 7,188,888 | +2,188,888 | $94.50M | $338.17M | 3.04% | +$243.67M |
| uniQure N.V.(QURE) | 5,959,595 | 6,727,777 | +768,182 | $97.44M | $309.88M | 2.78% | +$212.44M |
| Vera Therapeutics, Inc.(VERA) | 5,888,888 | 5,723,888 | -165,000 | $236.91M | $245.61M | 2.21% | +$8.70M |
| Taysha Gene Therapies, Inc.(TSHA) | 21,700,000 | 23,888,888 | +2,188,888 | $97.00M | $162.68M | 1.46% | +$65.68M |
| Ocular Therapeutix, Inc.(OCUL) | 12,315,000 | 12,540,000 | +225,000 | $104.31M | $123.14M | 1.11% | +$18.83M |
| Damora Therapeutics, Inc.(DMRA) | 3,783,000 | 3,783,000 | 0 | $97.98M | $98.40M | 0.88% | +$416.1K |
| Hemab Therapeutics Hldgs Inc | 0 | 1,925,150 | +1,925,150 | $0 | $70.71M | 0.63% | +$70.71M |
| GH Research PLC(GHRS) | 1,800,000 | 1,800,000 | 0 | $25.31M | $48.38M | 0.43% | +$23.08M |
| Viridian Therapeutics, Inc.(VRDN) | 1,500,000 | 2,500,000 | +1,000,000 | $29.34M | $45.92M | 0.41% | +$16.59M |
| Septerna, Inc.(SEPN) | 1,337,500 | 1,337,500 | 0 | $32.14M | $44.79M | 0.40% | +$12.65M |
| Avalo Therapeutics, Inc.(AVTX) | 1,410,000 | 2,333,333 | +923,333 | $21.05M | $43.12M | 0.39% | +$22.07M |
| Faeth Therapeutics, Inc.(FTH) | 0 | 1,444,039 | +1,444,039 | $0 | $36.10M | 0.32% | +$36.10M |
| Whitehawk Therapeutics, Inc.(WHWK) | 2,849,402 | 2,849,402 | 0 | $9.83M | $13.05M | 0.12% | +$3.22M |
| Lexeo Therapeutics, Inc.(LXEO) | 1,875,000 | 1,489,189 | -385,811 | $10.76M | $6.93M | 0.06% | -$3.83M |
| Alkermes plc(ALKS) | 1,200,000 | 0 | -1,200,000 | $42.43M | $0 | — | -$42.43M |
| Apellis Pharmaceuticals Inc COM | 12,222,222 | 0 | -12,222,222 | $491.70M | $0 | — | -$491.70M |
| Ascendis Pharma A/SADR(ASND) | 5,062,500 | 0 | -5,062,500 | $1.16B | $0 | — | -$1.16B |
| Centessa Pharmaceuticals PlcADS | 11,430,455 | 0 | -11,430,455 | $454.02M | $0 | — | -$454.02M |
| MannKind Corporation(MNKD) | 2,200,000 | 0 | -2,200,000 | $5.39M | $0 | — | -$5.39M |
| Soleno Therapeutics Inc | 2,300,000 | 0 | -2,300,000 | $77.00M | $0 | — | -$77.00M |
| Terns Pharmaceuticals Inc | 5,695,000 | 0 | -5,695,000 | $300.24M | $0 | — | -$300.24M |