Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q2 2024 ▲▼ | Q3 2024 ▲▼ | Change ▲▼ | Q2 2024 ▲▼ | Q3 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| United Therapeutics Corporation(UTHR) | 2,858,888 | 2,858,888 | 0 | $910.70M | $1.02B | 14.94% | +$113.78M |
| Ascendis Pharma A/SADR(ASND) | 4,196,661 | 4,988,888 | +792,227 | $572.34M | $744.89M | 10.86% | +$172.55M |
| argenx SEADR(ARGX) | 1,238,467 | 1,238,467 | 0 | $532.59M | $671.35M | 9.79% | +$138.76M |
| Krystal Biotech, Inc.(KRYS) | 2,433,000 | 2,622,222 | +189,222 | $446.80M | $477.32M | 6.96% | +$30.53M |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 2,055,555 | 2,029,000 | -26,555 | $575.88M | $430.59M | 6.28% | -$145.29M |
| Apellis Pharmaceuticals Inc. COM | 11,111,111 | 11,111,111 | 0 | $426.22M | $320.44M | 4.67% | -$105.78M |
| Sarepta Therapeutics, Inc.(SRPT) | 3,000,000 | 2,555,555 | -444,445 | $474.00M | $319.16M | 4.65% | -$154.84M |
| Avidity Biosciences Inc | 6,505,000 | 6,875,000 | +370,000 | $265.73M | $315.77M | 4.60% | +$50.04M |
| Amicus Therapeutics Inc. COM | 27,400,000 | 23,175,000 | -4,225,000 | $271.81M | $247.51M | 3.61% | -$24.30M |
| Intra-Cellular Therapies Inc | 3,000,000 | 3,050,000 | +50,000 | $205.47M | $223.17M | 3.25% | +$17.70M |
| Xenon Pharmaceuticals Inc.(XENE) | 5,666,666 | 5,666,666 | 0 | $220.94M | $223.10M | 3.25% | +$2.15M |
| Kymera Therapeutics, Inc.(KYMR) | 3,888,888 | 4,500,000 | +611,112 | $116.08M | $212.99M | 3.11% | +$96.90M |
| Vera Therapeutics, Inc.(VERA) | 4,309,590 | 4,309,590 | 0 | $155.92M | $190.48M | 2.78% | +$34.56M |
| Arrowhead Pharmaceuticals, Inc.(ARWR) | 8,888,888 | 8,888,888 | 0 | $231.02M | $172.18M | 2.51% | -$58.84M |
| BioMarin Pharmaceutical Inc.(BMRN) | 4,557,416 | 2,038,015 | -2,519,401 | $375.21M | $143.25M | 2.09% | -$231.96M |
| MoonLake ImmunotherapeuticsCL A(MLTX) | 2,770,000 | 2,770,100 | +100 | $121.80M | $139.67M | 2.04% | +$17.87M |
| Vaxcyte, Inc.(PCVX) | 575,000 | 1,175,000 | +600,000 | $43.42M | $134.27M | 1.96% | +$90.85M |
| Soleno Therapeutics Inc | 2,091,666 | 2,181,000 | +89,334 | $85.34M | $110.12M | 1.61% | +$24.78M |
| BioCryst Pharmaceuticals, Inc.(BCRX) | 12,570,000 | 11,865,000 | -705,000 | $77.68M | $90.17M | 1.31% | +$12.49M |
| Syndax Pharmaceuticals, Inc.(SNDX) | 3,888,437 | 3,888,437 | 0 | $79.83M | $74.85M | 1.09% | -$4.98M |
| Ocular Therapeutix, Inc.(OCUL) | 8,060,000 | 8,060,000 | 0 | $55.13M | $70.12M | 1.02% | +$14.99M |
| Kura Oncology, Inc.(KURA) | 3,541,505 | 3,541,505 | 0 | $72.92M | $69.20M | 1.01% | -$3.72M |
| Merus N V | 1,355,000 | 1,355,000 | 0 | $80.18M | $67.70M | 0.99% | -$12.48M |
| Tourmaline Bio Inc | 2,222,222 | 2,222,222 | 0 | $28.58M | $57.13M | 0.83% | +$28.56M |
| MannKind Corporation(MNKD) | 8,759,524 | 8,750,000 | -9,524 | $45.72M | $55.04M | 0.80% | +$9.31M |
| Ultragenyx Pharmaceutical Inc.(RARE) | 830,000 | 830,000 | 0 | $34.11M | $46.11M | 0.67% | +$11.99M |
| Autolus Therapeutics plcADR(AUTL) | 12,345,678 | 12,345,678 | 0 | $42.96M | $44.81M | 0.65% | +$1.85M |
| Iovance Biotherapeutics, Inc.(IOVA) | 11,700,000 | 4,240,000 | -7,460,000 | $93.83M | $39.81M | 0.58% | -$54.02M |
| Taysha Gene Therapies, Inc.(TSHA) | 18,650,000 | 18,650,000 | 0 | $41.78M | $37.49M | 0.55% | -$4.29M |
| Monte Rosa Therapeutics, Inc.(GLUE) | 4,535,000 | 5,790,236 | +1,255,236 | $16.96M | $30.69M | 0.45% | +$13.73M |
| CG Oncology, Inc.(CGON) | 700,000 | 700,000 | 0 | $22.10M | $26.41M | 0.39% | +$4.31M |
| Dyne Therapeutics, Inc.(DYN) | 115,751 | 650,000 | +534,249 | $4.08M | $23.35M | 0.34% | +$19.26M |
| Spyre Therapeutics, Inc.(SYRE) | 1,839,138 | 598,600 | -1,240,538 | $43.24M | $17.60M | 0.26% | -$25.63M |
| Whitehawk Therapeutics, Inc.(WHWK) | 2,849,402 | 2,849,402 | 0 | $4.16M | $5.87M | 0.09% | +$1.71M |
| Neurogene Inc.(NGNE) | 22,029 | 22,029 | 0 | $801.6K | $924.3K | 0.01% | +$122.7K |
| Adverum Biotechnologies Inc | 416,666 | 0 | -416,666 | $2.86M | $0 | — | -$2.86M |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 400,000 | 0 | -400,000 | $97.20M | $0 | — | -$97.20M |
| Bicycle Therapeutics PlcADR | 700,000 | 0 | -700,000 | $14.17M | $0 | — | -$14.17M |
| Cerevel Therapeutics Hldng | 7,539,547 | 0 | -7,539,547 | $308.29M | $0 | — | -$308.29M |
| Spdr Series Trust - S&p BiotechETF ST STR SP BIOT | 3,035,000 | 0 | -3,035,000 | $281.37M | $0 | — | -$281.37M |
| Verrica Pharmaceuticals Inc.(VRCA) | 3,999,999 | 0 | -3,999,999 | $29.16M | $0 | — | -$29.16M |