Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Vertex Pharmaceuticals Incorporated(VRTX) | 681,120 | 681,908 | +788 | $308.79M | $304.50M | 7.25% | -$4.29M |
| argenx SEADR(ARGX) | 461,854 | 313,000 | -148,854 | $388.40M | $228.57M | 5.44% | -$159.83M |
| Regeneron Pharmaceuticals, Inc.(REGN) | 13,928 | 278,674 | +264,746 | $10.75M | $215.31M | 5.12% | +$204.56M |
| Scholar Rock Holding Corporation(SRRK) | 4,056,592 | 3,584,573 | -472,019 | $178.69M | $176.22M | 4.19% | -$2.48M |
| Gilead Sciences, Inc.(GILD) | 52,752 | 1,169,879 | +1,117,127 | $6.47M | $163.05M | 3.88% | +$156.57M |
| Revolution Medicines, Inc.(RVMD) | 5,005,719 | 1,544,456 | -3,461,263 | $398.71M | $150.20M | 3.57% | -$248.51M |
| Ionis Pharmaceuticals, Inc.(IONS) | 4,802,199 | 1,818,665 | -2,983,534 | $379.90M | $136.56M | 3.25% | -$243.34M |
| Intuitive Surgical, Inc.(ISRG) | 322,028 | 286,654 | -35,374 | $182.38M | $132.14M | 3.14% | -$50.24M |
| Viridian Therapeutics, Inc.(VRDN) | 4,358,527 | 6,726,144 | +2,367,617 | $135.64M | $131.56M | 3.13% | -$4.07M |
| Krystal Biotech, Inc.(KRYS) | 410,323 | 481,785 | +71,462 | $101.16M | $124.45M | 2.96% | +$23.29M |
| Crinetics Pharmaceuticals In | 4,040 | 3,280,000 | +3,275,960 | $188.1K | $119.13M | 2.84% | +$118.94M |
| Abbott Laboratories | 1,316,915 | 1,151,635 | -165,280 | $165.00M | $118.24M | 2.81% | -$46.76M |
| Nuvalent Inc | 1,037,468 | 1,053,268 | +15,800 | $104.36M | $107.91M | 2.57% | +$3.55M |
| Amgen Inc.(AMGN) | 18,489 | 295,358 | +276,869 | $6.05M | $103.92M | 2.47% | +$97.87M |
| Boston Scientific Corporation(BSX) | 1,559,606 | 1,466,894 | -92,712 | $148.71M | $92.05M | 2.19% | -$56.66M |
| Enliven Therapeutics Inc | 0 | 2,320,867 | +2,320,867 | $0 | $90.98M | 2.17% | +$90.98M |
| Immunocore Holdings plcADS(IMCR) | 2,796,803 | 2,796,803 | 0 | $97.08M | $84.32M | 2.01% | -$12.75M |
| Medtronic plcSHS(MDT) | 766,592 | 957,329 | +190,737 | $73.64M | $82.95M | 1.97% | +$9.31M |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 445,903 | 234,543 | -211,360 | $177.31M | $77.60M | 1.85% | -$99.71M |
| Relay Therapeutics, Inc.(RLAY) | 8,345,364 | 7,795,242 | -550,122 | $70.60M | $77.56M | 1.85% | +$6.96M |
| Stryker Corporation(SYK) | 360,577 | 217,237 | -143,340 | $126.73M | $71.38M | 1.70% | -$55.35M |
| Vaxcyte, Inc.(PCVX) | 0 | 1,190,697 | +1,190,697 | $0 | $69.19M | 1.65% | +$69.19M |
| Vera Therapeutics, Inc.CL A(VERA) | 1,698,152 | 1,710,771 | +12,619 | $85.99M | $68.82M | 1.64% | -$17.17M |
| Edwards Lifesciences Corp | 1,043,096 | 839,451 | -203,645 | $88.92M | $67.22M | 1.60% | -$21.70M |
| Damora Therapeutics, Inc.(DMRA) | 0 | 2,298,000 | +2,298,000 | $0 | $59.52M | 1.42% | +$59.52M |
| Tango Therapeutics, Inc.(TNGX) | 3,927,670 | 2,400,000 | -1,527,670 | $34.80M | $50.21M | 1.19% | +$15.41M |
| IDEXX Laboratories, Inc.(IDXX) | 94,539 | 89,131 | -5,408 | $63.96M | $50.08M | 1.19% | -$13.88M |
| Ultragenyx Pharmaceutical Inc.(RARE) | 2,580 | 2,380,000 | +2,377,420 | $59.3K | $49.86M | 1.19% | +$49.80M |
| DexCom, Inc.(DXCM) | 847,405 | 788,766 | -58,639 | $56.24M | $49.53M | 1.18% | -$6.71M |
| Jade Biosciences Inc | 3,341,103 | 3,501,502 | +160,399 | $51.55M | $49.20M | 1.17% | -$2.36M |
| Edgewise Therapeutics, Inc.(EWTX) | 1,528,518 | 1,528,518 | 0 | $37.93M | $48.15M | 1.15% | +$10.22M |
| UnitedHealth Group Incorporated(UNH) | 175,169 | 148,203 | -26,966 | $57.83M | $40.10M | 0.95% | -$17.72M |
| Danaher Corporation(DHR) | 194,633 | 202,164 | +7,531 | $44.56M | $38.33M | 0.91% | -$6.23M |
| Celldex Therapeutics, Inc.(CLDX) | 3,617,669 | 1,200,000 | -2,417,669 | $98.26M | $38.06M | 0.91% | -$60.19M |
| ResMed Inc.(RMD) | 161,214 | 159,346 | -1,868 | $38.83M | $35.77M | 0.85% | -$3.06M |
| Insulet Corporation(PODD) | 186,699 | 163,656 | -23,043 | $53.07M | $34.34M | 0.82% | -$18.73M |
| Thermo Fisher Scientific Inc.(TMO) | 65,077 | 64,412 | -665 | $37.71M | $31.66M | 0.75% | -$6.05M |
| Eli Lilly and Company(LLY) | 34,003 | 33,932 | -71 | $36.54M | $31.21M | 0.74% | -$5.33M |
| GE HealthCare Technologies Inc.(GEHC) | 424,514 | 416,887 | -7,627 | $34.82M | $29.67M | 0.71% | -$5.14M |
| Disc Medicine, Inc.(IRON) | 0 | 459,314 | +459,314 | $0 | $29.37M | 0.70% | +$29.37M |
| Johnson & Johnson(JNJ) | 126,800 | 119,102 | -7,698 | $26.24M | $29.11M | 0.69% | +$2.87M |
| Annexon, Inc.(ANNX) | 5,157,290 | 5,157,290 | 0 | $25.89M | $28.57M | 0.68% | +$2.68M |
| The Cigna Group(CI) | 110,013 | 98,263 | -11,750 | $30.28M | $26.21M | 0.62% | -$4.07M |
| Oruka Therapeutics, Inc.(ORKA) | 0 | 507,008 | +507,008 | $0 | $24.87M | 0.59% | +$24.87M |
| Merck & Co., Inc.(MRK) | 92,117 | 206,591 | +114,474 | $9.70M | $24.85M | 0.59% | +$15.15M |
| Align Technology Inc | 141,474 | 139,680 | -1,794 | $22.09M | $23.95M | 0.57% | +$1.85M |
| STERIS plcSHS USD(STE) | 101,705 | 99,878 | -1,827 | $25.78M | $22.09M | 0.53% | -$3.70M |
| Globus Medical, Inc.CL A(GMED) | 262,683 | 247,261 | -15,422 | $22.93M | $21.30M | 0.51% | -$1.63M |
| Monte Rosa Therapeutics, Inc.(GLUE) | 0 | 1,250,000 | +1,250,000 | $0 | $20.56M | 0.49% | +$20.56M |
| AbbVie Inc.(ABBV) | 134,859 | 93,567 | -41,292 | $30.81M | $20.35M | 0.48% | -$10.46M |
| The Cooper Companies, Inc.(COO) | 291,959 | 272,184 | -19,775 | $23.93M | $19.46M | 0.46% | -$4.47M |
| McKesson Corporation(MCK) | 25,098 | 22,352 | -2,746 | $20.59M | $19.34M | 0.46% | -$1.25M |
| Becton, Dickinson and Company(BDX) | 265,662 | 121,887 | -143,775 | $51.56M | $19.16M | 0.46% | -$32.39M |
| HCA Healthcare, Inc.(HCA) | 43,906 | 37,765 | -6,141 | $20.50M | $17.87M | 0.43% | -$2.63M |
| Glaukos Corporation(GKOS) | 261,935 | 145,703 | -116,232 | $29.58M | $15.69M | 0.37% | -$13.89M |
| Elevance Health, Inc.(ELV) | 69,645 | 52,518 | -17,127 | $24.41M | $15.37M | 0.37% | -$9.04M |
| Zimmer Biomet Holdings, Inc.(ZBH) | 238,680 | 155,571 | -83,109 | $21.46M | $14.07M | 0.33% | -$7.40M |
| PROCEPT BioRobotics Corporation(PRCT) | 515,430 | 502,286 | -13,144 | $16.22M | $12.56M | 0.30% | -$3.65M |
| LivaNova PLCSHS(LIVN) | 0 | 186,185 | +186,185 | $0 | $11.83M | 0.28% | +$11.83M |
| Humana Inc.(HUM) | 73,081 | 64,498 | -8,583 | $18.72M | $11.18M | 0.27% | -$7.53M |
| TransMedics Group, Inc.(TMDX) | 97,885 | 101,139 | +3,254 | $11.91M | $10.05M | 0.24% | -$1.85M |
| Veeva Systems Inc.CL A(VEEV) | 80,529 | 56,517 | -24,012 | $17.98M | $9.93M | 0.24% | -$8.05M |
| Centene Corporation(CNC) | 273,674 | 261,066 | -12,608 | $11.26M | $8.55M | 0.20% | -$2.71M |
| Teva Pharmaceutical Industries LimitedADS(TEVA) | 327,863 | 250,082 | -77,781 | $10.23M | $7.53M | 0.18% | -$2.70M |
| Tenet Healthcare Corporation(THC) | 40,239 | 38,269 | -1,970 | $8.00M | $7.22M | 0.17% | -$774.6K |
| 10x Genomics, Inc.CL A(TXG) | 322,060 | 329,492 | +7,432 | $5.25M | $7.00M | 0.17% | +$1.74M |
| CVS Health Corporation(CVS) | 109,058 | 89,363 | -19,695 | $8.65M | $6.42M | 0.15% | -$2.24M |
| Natera, Inc.(NTRA) | 56,036 | 31,694 | -24,342 | $12.84M | $6.34M | 0.15% | -$6.50M |
| Waystar Holding Corp.(WAY) | 241,734 | 256,139 | +14,405 | $7.92M | $6.18M | 0.15% | -$1.74M |
| Medline Inc.CL A(MDLN) | 117,720 | 136,635 | +18,915 | $4.94M | $6.08M | 0.14% | +$1.14M |
| Inspire Medical Systems, Inc.(INSP) | 100,761 | 99,735 | -1,026 | $9.29M | $5.14M | 0.12% | -$4.15M |
| Privia Health Group, Inc.(PRVA) | 448,163 | 226,703 | -221,460 | $10.63M | $4.66M | 0.11% | -$5.96M |
| Penumbra, Inc.(PEN) | 135,395 | 12,267 | -123,128 | $42.10M | $4.03M | 0.10% | -$38.07M |
| Atrium Therapeutics, Inc.(RNA) | 0 | 263,096 | +263,096 | $0 | $3.52M | 0.08% | +$3.52M |
| Pfizer Inc.(PFE) | 56,847 | 107,635 | +50,788 | $1.42M | $3.02M | 0.07% | +$1.61M |
| Illumina, Inc.(ILMN) | 22,940 | 20,223 | -2,717 | $3.01M | $2.49M | 0.06% | -$516.1K |
| Kestra Med Technologies LtdSHS SHS | 115,755 | 115,590 | -165 | $3.07M | $2.30M | 0.05% | -$766.1K |
| Omada Health, Inc.(OMDA) | 177,897 | 157,938 | -19,959 | $2.81M | $1.99M | 0.05% | -$821.9K |
| BridgeBio Pharma, Inc.(BBIO) | 24,111 | 25,377 | +1,266 | $1.84M | $1.88M | 0.04% | +$40.2K |
| BioNTech SEADS(BNTX) | 43,755 | 20,851 | -22,904 | $4.17M | $1.85M | 0.04% | -$2.31M |
| Royalty Pharma plcCL A(RPRX) | 13,201 | 38,296 | +25,095 | $510.1K | $1.84M | 0.04% | +$1.33M |
| State Street SPDR S&P 500 ETF TrustTR UNIT(SPY) | 3,100 | 2,700 | -400 | $2.11M | $1.76M | 0.04% | -$358.0K |
| Insmed Incorporated(INSM) | 13,915 | 10,034 | -3,881 | $2.42M | $1.64M | 0.04% | -$781.0K |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 2,884 | 3,040 | +156 | $1.68M | $1.59M | 0.04% | -$88.1K |
| Masimo Corp | 97,285 | 8,753 | -88,532 | $12.65M | $1.56M | 0.04% | -$11.10M |
| Protagonist Therapeutics Inc | 16,543 | 14,447 | -2,096 | $1.44M | $1.52M | 0.04% | +$77.8K |
| United Therapeutics Corporation(UTHR) | 3,895 | 2,077 | -1,818 | $1.90M | $1.23M | 0.03% | -$666.2K |
| BeOne Medicines AGADS(ONC) | 1,890 | 3,812 | +1,922 | $574.2K | $1.13M | 0.03% | +$557.8K |
| Phreesia, Inc.(PHR) | 183,213 | 130,992 | -52,221 | $3.10M | $1.10M | 0.03% | -$2.00M |
| Adaptive Biotechnologies Corporation(ADPT) | 298,090 | 76,181 | -221,909 | $4.84M | $1.06M | 0.03% | -$3.78M |
| Bristol-Myers Squibb Company(BMY) | 67,082 | 17,038 | -50,044 | $3.62M | $1.03M | 0.02% | -$2.59M |
| Encompass Health Corporation(EHC) | 19,089 | 9,829 | -9,260 | $2.03M | $950.8K | 0.02% | -$1.08M |
| Newamsterdam Pharma Company ORDINARY SHARES | 36,336 | 27,661 | -8,675 | $1.27M | $885.4K | 0.02% | -$389.2K |
| Apple Inc.(AAPL) | 3,320 | 3,320 | 0 | $902.6K | $842.6K | 0.02% | -$60.0K |
| Billiontoone IncCL A | 10,589 | 10,554 | -35 | $866.6K | $833.1K | 0.02% | -$33.5K |
| Mineralys Therapeutics, Inc.(MLYS) | 19,826 | 29,374 | +9,548 | $719.5K | $795.7K | 0.02% | +$76.3K |
| Equinor ASAADR(EQNR) | 0 | 17,573 | +17,573 | $0 | $741.6K | 0.02% | +$741.6K |
| Exxon Mobil Corp | 0 | 4,370 | +4,370 | $0 | $741.4K | 0.02% | +$741.4K |
| BP p.l.c.ADR(BP) | 0 | 15,644 | +15,644 | $0 | $735.3K | 0.02% | +$735.3K |
| Shell plcADS(SHEL) | 0 | 7,844 | +7,844 | $0 | $729.5K | 0.02% | +$729.5K |