Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q1 2025 ▲▼ | Q2 2025 ▲▼ | Change ▲▼ | Q1 2025 ▲▼ | Q2 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| IONIS PHARMACEUTICALS INC(IONS) | 7,853,198 | 7,853,198 | 0 | 236,931 | 310,280 | 6.84% | +73,349 |
| AKERO THERAPEUTICS INC | 1,250,666 | 1,985,272 | +734,606 | 50,627 | 105,934 | 2.33% | +55,307 |
| IMMUNOCORE HLDGS PLC(IMCR) | 1,221,794 | 2,441,830 | +1,220,036 | 36,251 | 76,625 | 1.69% | +40,374 |
| BLUEPRINT MEDICINES CORP | 0 | 284,900 | +284,900 | 0 | 36,518 | 0.80% | +36,518 |
| NEUROCRINE BIOSCIENCES INC(NBIX) | 1,820,000 | 1,820,000 | 0 | 201,292 | 228,756 | 5.04% | +27,464 |
| SCHOLAR ROCK HLDG CORP(SRRK) | 2,506,890 | 2,947,295 | +440,405 | 80,597 | 104,393 | 2.30% | +23,797 |
| HCA HEALTHCARE INC(HCA) | 61,807 | 99,122 | +37,315 | 21,357 | 37,974 | 0.84% | +16,616 |
| AGIOS PHARMACEUTICALS INC(AGIO) | 3,515,150 | 3,590,150 | +75,000 | 102,994 | 119,408 | 2.63% | +16,414 |
| ELEVANCE HEALTH INC(ELV) | 40,058 | 82,053 | +41,995 | 17,424 | 31,915 | 0.70% | +14,492 |
| THERMO FISHER SCIENTIFIC INC(TMO) | 64,232 | 113,544 | +49,312 | 31,962 | 46,038 | 1.01% | +14,076 |
| REVOLUTION MEDICINES INC(RVMD) | 4,374,300 | 4,579,300 | +205,000 | 154,675 | 168,472 | 3.71% | +13,797 |
| ALNYLAM PHARMACEUTICALS INC(ALNY) | 768,147 | 676,367 | -91,780 | 207,415 | 220,557 | 4.86% | +13,141 |
| CELLDEX THERAPEUTICS INC NEW(CLDX) | 3,071,615 | 3,307,569 | +235,954 | 55,750 | 67,309 | 1.48% | +11,559 |
| RELAY THERAPEUTICS INC(RLAY) | 7,377,292 | 8,230,870 | +853,578 | 19,329 | 28,479 | 0.63% | +9,150 |
| MCKESSON CORP(MCK) | 30,580 | 40,466 | +9,886 | 20,580 | 29,653 | 0.65% | +9,073 |
| NATERA INC(NTRA) | 113,219 | 147,491 | +34,272 | 16,010 | 24,917 | 0.55% | +8,907 |
| IDEXX LABS INC(IDXX) | 76,897 | 76,548 | -349 | 32,293 | 41,056 | 0.90% | +8,763 |
| QUEST DIAGNOSTICS INC(DGX) | 0 | 48,567 | +48,567 | 0 | 8,724 | 0.19% | +8,724 |
| TEVA PHARMACEUTICAL INDS LTD(TEVA) | 28,930 | 421,501 | +392,571 | 445 | 7,064 | 0.16% | +6,620 |
| VEEVA SYS INC(VEEV) | 113,250 | 113,333 | +83 | 26,232 | 32,638 | 0.72% | +6,406 |
| ABBOTT LABS | 1,556,129 | 1,564,022 | +7,893 | 206,421 | 212,723 | 4.69% | +6,302 |
| TRANSMEDICS GROUP INC(TMDX) | 173,710 | 130,517 | -43,193 | 11,687 | 17,491 | 0.39% | +5,803 |
| RESMED INC(RMD) | 165,802 | 165,802 | 0 | 37,115 | 42,777 | 0.94% | +5,662 |
| EDGEWISE THERAPEUTICS INC(EWTX) | 1,428,929 | 2,775,997 | +1,347,068 | 31,436 | 36,393 | 0.80% | +4,957 |
| ASCENDIS PHARMA A/S(ASND) | 1,900 | 28,655 | +26,755 | 296 | 4,946 | 0.11% | +4,650 |
| OMADA HEALTH INC(OMDA) | 0 | 250,000 | +250,000 | 0 | 4,575 | 0.10% | +4,575 |
| ALIGN TECHNOLOGY INC | 150,993 | 150,787 | -206 | 23,987 | 28,549 | 0.63% | +4,562 |
| HUMANA INC(HUM) | 28,298 | 49,124 | +20,826 | 7,488 | 12,010 | 0.26% | +4,522 |
| PROCEPT BIOROBOTICS CORP(PRCT) | 414,923 | 489,278 | +74,355 | 24,173 | 28,182 | 0.62% | +4,009 |
| MASIMO CORP | 69,808 | 89,673 | +19,865 | 11,630 | 15,085 | 0.33% | +3,455 |
| STRUCTURE THERAPEUTICS INC | 221,715 | 348,527 | +126,812 | 3,838 | 7,228 | 0.16% | +3,391 |
| LABCORP HOLDINGS INC(LH) | 28,141 | 36,692 | +8,551 | 6,550 | 9,632 | 0.21% | +3,082 |
| BIONTECH SE(BNTX) | 7,964 | 35,039 | +27,075 | 725 | 3,731 | 0.08% | +3,005 |
| BLACK DIAMOND THERAPEUTICS I | 2,733,547 | 2,733,547 | 0 | 4,237 | 6,779 | 0.15% | +2,542 |
| DEXCOM INC(DXCM) | 1,064,108 | 860,828 | -203,280 | 72,668 | 75,142 | 1.66% | +2,474 |
| ANNEXON INC(ANNX) | 5,157,290 | 5,157,290 | 0 | 9,954 | 12,377 | 0.27% | +2,424 |
| BEAM THERAPEUTICS INC(BEAM) | 2,395,930 | 2,889,288 | +493,358 | 46,793 | 49,147 | 1.08% | +2,354 |
| CENTENE CORP DEL(CNC) | 86,218 | 139,310 | +53,092 | 5,234 | 7,562 | 0.17% | +2,327 |
| 10X GENOMICS INC(TXG) | 230,997 | 326,751 | +95,754 | 2,017 | 3,784 | 0.08% | +1,767 |
| DANAHER CORPORATION(DHR) | 124,321 | 136,811 | +12,490 | 25,486 | 27,026 | 0.60% | +1,540 |
| STERIS PLC(STE) | 109,887 | 109,887 | 0 | 24,906 | 26,397 | 0.58% | +1,491 |
| ABBVIE INC(ABBV) | 135,240 | 159,661 | +24,421 | 28,335 | 29,636 | 0.65% | +1,301 |
| HOLOGIC INC | 247,886 | 247,886 | 0 | 15,312 | 16,152 | 0.36% | +840 |
| STRYKER CORPORATION(SYK) | 566,597 | 535,089 | -31,508 | 210,916 | 211,697 | 4.67% | +782 |
| WAYSTAR HLDG CORP(WAY) | 144,426 | 150,610 | +6,184 | 5,396 | 6,155 | 0.14% | +760 |
| CARDINAL HEALTH INC(CAH) | 20,776 | 20,012 | -764 | 2,862 | 3,362 | 0.07% | +500 |
| RHYTHM PHARMACEUTICALS INC(RYTM) | 15,550 | 20,906 | +5,356 | 824 | 1,321 | 0.03% | +497 |
| NOVO-NORDISK A S(NVO) | 0 | 6,500 | +6,500 | 0 | 449 | 0.01% | +449 |
| ILLUMINA INC(ILMN) | 27,624 | 27,624 | 0 | 2,192 | 2,636 | 0.06% | +444 |
| PLANET FITNESS INC(PLNT) | 0 | 2,700 | +2,700 | 0 | 294 | 0.01% | +294 |
| GLAUKOS CORP(GKOS) | 55,926 | 55,926 | 0 | 5,504 | 5,777 | 0.13% | +272 |
| CARIS LIFE SCIENCES INC(CAI) | 0 | 10,000 | +10,000 | 0 | 267 | 0.01% | +267 |
| PROTAGONIST THERAPEUTICS INC | 17,622 | 19,472 | +1,850 | 852 | 1,076 | 0.02% | +224 |
| METSERA INC | 0 | 7,800 | +7,800 | 0 | 222 | 0.00% | +222 |
| BRISTOL-MYERS SQUIBB CO(BMY) | 25,566 | 37,177 | +11,611 | 1,559 | 1,721 | 0.04% | +162 |
| VANECK ETF TRUST GOLD MINERS ETF | 26,200 | 26,200 | 0 | 1,204 | 1,364 | 0.03% | +160 |
| BETA BIONICS INC(BBNX) | 66,825 | 66,825 | 0 | 818 | 973 | 0.02% | +155 |
| BRIGHTSPRING HEALTH SVCS INC(BTSG) | 241,749 | 191,706 | -50,043 | 4,373 | 4,522 | 0.10% | +149 |
| CERTARA INC(CERT) | 81,740 | 81,740 | 0 | 809 | 956 | 0.02% | +147 |
| BELLRING BRANDS INC(BRBR) | 1,400 | 3,500 | +2,100 | 104 | 203 | 0.00% | +99 |
| BRIDGEBIO PHARMA INC(BBIO) | 10,400 | 10,400 | 0 | 360 | 449 | 0.01% | +90 |
| ALPHABET INC(GOOG) | 1,100 | 1,450 | +350 | 170 | 256 | 0.01% | +85 |
| AMAZON COM INC(AMZN) | 900 | 1,150 | +250 | 171 | 252 | 0.01% | +81 |
| DOXIMITY INC(DOCS) | 23,816 | 23,816 | 0 | 1,382 | 1,461 | 0.03% | +79 |
| MERUS N V | 8,000 | 7,765 | -235 | 337 | 408 | 0.01% | +72 |
| EXELIXIS INC(EXEL) | 8,500 | 8,500 | 0 | 314 | 375 | 0.01% | +61 |
| ORACLE CORP(ORCL) | 654 | 654 | 0 | 91 | 143 | 0.00% | +52 |
| ISHARES TR | 2,300 | 2,300 | 0 | 459 | 496 | 0.01% | +37 |
| NVIDIA CORPORATION(NVDA) | 751 | 751 | 0 | 81 | 119 | 0.00% | +37 |
| UNIQURE NV(QURE) | 22,500 | 19,610 | -2,890 | 239 | 273 | 0.01% | +35 |
| MICROSOFT CORP(MSFT) | 203 | 203 | 0 | 76 | 101 | 0.00% | +25 |
| MOONLAKE IMMUNOTHERAPEUTICS(MLTX) | 3,000 | 3,000 | 0 | 117 | 142 | 0.00% | +24 |
| TEMPUS AI INC(TEM) | 237 | 237 | 0 | 11 | 15 | 0.00% | +4 |
| QUALCOMM INC(QCOM) | 447 | 447 | 0 | 69 | 71 | 0.00% | +3 |
| AGILENT TECHNOLOGIES INC(A) | 806 | 806 | 0 | 94 | 95 | 0.00% | +1 |
| ARCELLX INC COMMON STOCK | 3,000 | 3,000 | 0 | 197 | 198 | 0.00% | +1 |
| METTLER TOLEDO INTERNATIONAL(MTD) | 42 | 42 | 0 | 50 | 49 | 0.00% | -0 |
| BIOGEN INC(BIIB) | 402 | 402 | 0 | 55 | 50 | 0.00% | -5 |
| GARMIN LTD(GRMN) | 850 | 850 | 0 | 185 | 177 | 0.00% | -7 |
| PTC THERAPEUTICS INC(PTCT) | 3,800 | 3,800 | 0 | 194 | 186 | 0.00% | -8 |
| BAIDU INC | 2,000 | 2,000 | 0 | 184 | 172 | 0.00% | -13 |
| CYTOKINETICS INC(CYTK) | 3,741 | 3,741 | 0 | 150 | 124 | 0.00% | -27 |
| ADMA BIOLOGICS INC | 16,900 | 16,900 | 0 | 335 | 308 | 0.01% | -28 |
| MADRIGAL PHARMACEUTICALS INC(MDGL) | 1,100 | 1,100 | 0 | 364 | 333 | 0.01% | -31 |
| MINERALYS THERAPEUTICS INC(MLYS) | 16,499 | 15,556 | -943 | 262 | 210 | 0.00% | -52 |
| LEGEND BIOTECH CORP(LEGN) | 91,191 | 85,438 | -5,753 | 3,094 | 3,032 | 0.07% | -62 |
| NEWAMSTERDAM PHARMA COMPANY ORDINARY SHARES | 21,800 | 20,555 | -1,245 | 446 | 372 | 0.01% | -74 |
| CVS HEALTH CORP(CVS) | 31,755 | 30,096 | -1,659 | 2,151 | 2,076 | 0.05% | -75 |
| OCULIS HOLDING AG(OCS) | 14,100 | 9,700 | -4,400 | 268 | 188 | 0.00% | -80 |
| TRAVERE THERAPEUTICS INC(TVTX) | 23,100 | 18,303 | -4,797 | 414 | 271 | 0.01% | -143 |
| PHREESIA INC(PHR) | 376,163 | 332,016 | -44,147 | 9,615 | 9,449 | 0.21% | -166 |
| ARCUTIS BIOTHERAPEUTICS INC(ARQT) | 35,700 | 24,008 | -11,692 | 558 | 337 | 0.01% | -222 |
| BEONE MEDICINES LTD(ONC) | 35,329 | 38,698 | +3,369 | 9,615 | 9,368 | 0.21% | -248 |
| ASTRAZENECA PLC(AZN) | 40,000 | 38,400 | -1,600 | 2,940 | 2,683 | 0.06% | -257 |
| KRYSTAL BIOTECH INC(KRYS) | 2,650 | 1,250 | -1,400 | 478 | 172 | 0.00% | -306 |
| ZOETIS INC(ZTS) | 3,114 | 657 | -2,457 | 513 | 102 | 0.00% | -410 |
| SUMMIT THERAPEUTICS INC(SMMT) | 67,685 | 41,738 | -25,947 | 1,306 | 888 | 0.02% | -417 |
| VAXCYTE INC(PCVX) | 11,290 | 0 | -11,290 | 426 | 0 | — | -426 |
| GILEAD SCIENCES INC(GILD) | 55,022 | 51,416 | -3,606 | 6,165 | 5,700 | 0.13% | -465 |
| MACROGENICS INC(MGNX) | 9,929,963 | 9,919,992 | -9,971 | 12,611 | 12,003 | 0.26% | -608 |