Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q3 2023 ▲▼ | Q4 2023 ▲▼ | Change ▲▼ | Q3 2023 ▲▼ | Q4 2023 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| IMMUNOCORE HLDGS PLC(IMCR) | 19,850 | 976,054 | +956,204 | 1,030 | 66,684 | 1.02% | +65,654 |
| ARVINAS INC(ARVN) | 2,125,200 | 2,507,731 | +382,531 | 41,739 | 103,218 | 1.58% | +61,479 |
| INTRA-CELLULAR THERAPIES INC | 3,170,250 | 3,066,400 | -103,850 | 165,138 | 219,616 | 3.36% | +54,477 |
| MACROGENICS INC(MGNX) | 9,803,313 | 9,953,313 | +150,000 | 45,683 | 95,751 | 1.46% | +50,067 |
| DEXCOM INC(DXCM) | 685,733 | 914,593 | +228,860 | 63,979 | 113,492 | 1.74% | +49,513 |
| BIOHAVEN LTD(BHVN) | 0 | 1,075,000 | +1,075,000 | 0 | 46,010 | 0.70% | +46,010 |
| BOSTON SCIENTIFIC CORP(BSX) | 2,646,295 | 3,170,603 | +524,308 | 139,724 | 183,293 | 2.80% | +43,568 |
| CELLDEX THERAPEUTICS INC NEW(CLDX) | 1,900,000 | 2,416,296 | +516,296 | 52,288 | 95,830 | 1.47% | +43,542 |
| GE HEALTHCARE TECHNOLOGIES I(GEHC) | 12,500 | 535,184 | +522,684 | 851 | 41,380 | 0.63% | +40,530 |
| INTUITIVE SURGICAL INC | 828,999 | 832,041 | +3,042 | 242,308 | 280,697 | 4.29% | +38,389 |
| MODERNA INC(MRNA) | 1,495,325 | 1,908,420 | +413,095 | 154,452 | 189,792 | 2.90% | +35,340 |
| INSPIRE MED SYS INC(INSP) | 70,368 | 215,600 | +145,232 | 13,964 | 43,860 | 0.67% | +29,896 |
| MEDTRONIC PLC(MDT) | 641,492 | 970,772 | +329,280 | 50,267 | 79,972 | 1.22% | +29,705 |
| NEUROCRINE BIOSCIENCES INC(NBIX) | 2,583,550 | 2,430,500 | -153,050 | 290,649 | 320,243 | 4.90% | +29,593 |
| ESSA PHARMA INC | 7,898,583 | 7,898,583 | 0 | 24,407 | 52,131 | 0.80% | +27,724 |
| SCHOLAR ROCK HLDG CORP(SRRK) | 2,137,925 | 2,168,925 | +31,000 | 15,179 | 40,776 | 0.62% | +25,597 |
| RELAY THERAPEUTICS INC(RLAY) | 4,885,000 | 5,936,082 | +1,051,082 | 41,083 | 65,356 | 1.00% | +24,273 |
| CENCORA INC | 17,087 | 126,126 | +109,039 | 3,075 | 25,904 | 0.40% | +22,829 |
| IONIS PHARMACEUTICALS INC(IONS) | 9,233,700 | 8,713,987 | -519,713 | 418,841 | 440,841 | 6.74% | +22,000 |
| INSULET CORP(PODD) | 264,359 | 289,900 | +25,541 | 42,163 | 62,903 | 0.96% | +20,740 |
| CAREDX INC(CDNA) | 3,940,798 | 3,954,792 | +13,994 | 27,586 | 47,458 | 0.73% | +19,872 |
| APELLIS PHARMACEUTICALS INC COM | 793,841 | 821,800 | +27,959 | 30,198 | 49,193 | 0.75% | +18,995 |
| ABBOTT LABS | 1,560,968 | 1,535,656 | -25,312 | 151,180 | 169,030 | 2.59% | +17,850 |
| BECTON DICKINSON & CO(BDX) | 304,230 | 388,068 | +83,838 | 78,653 | 94,623 | 1.45% | +15,970 |
| CRISPR THERAPEUTICS AG(CRSP) | 898,400 | 900,400 | +2,000 | 40,778 | 56,365 | 0.86% | +15,587 |
| REVOLUTION MEDICINES INC(RVMD) | 4,721,500 | 5,091,000 | +369,500 | 130,691 | 146,010 | 2.23% | +15,319 |
| TANDEM DIABETES CARE INC(TNDM) | 2,142,769 | 1,992,317 | -150,452 | 44,505 | 58,933 | 0.90% | +14,427 |
| TRANSMEDICS GROUP INC(TMDX) | 536,737 | 518,890 | -17,847 | 29,386 | 40,956 | 0.63% | +11,570 |
| PACIFIC BIOSCIENCES CALIF IN(PACB) | 7,245,188 | 7,317,128 | +71,940 | 60,497 | 71,781 | 1.10% | +11,284 |
| ALNYLAM PHARMACEUTICALS INC(ALNY) | 894,345 | 885,318 | -9,027 | 158,389 | 169,459 | 2.59% | +11,070 |
| STRYKER CORPORATION(SYK) | 475,613 | 465,724 | -9,889 | 129,971 | 139,466 | 2.13% | +9,495 |
| ESPERION THERAPEUTICS INC NE | 4,204,264 | 4,204,264 | 0 | 4,120 | 12,571 | 0.19% | +8,451 |
| PROCEPT BIOROBOTICS CORP(PRCT) | 888,296 | 885,346 | -2,950 | 29,145 | 37,105 | 0.57% | +7,960 |
| FATE THERAPEUTICS INC(FATE) | 4,851,579 | 4,851,579 | 0 | 10,285 | 18,145 | 0.28% | +7,860 |
| EDWARDS LIFESCIENCES CORP | 1,025,457 | 1,018,998 | -6,459 | 71,044 | 77,699 | 1.19% | +6,655 |
| CHARLES RIV LABS INTL INC(CRL) | 229,342 | 217,756 | -11,586 | 44,946 | 51,478 | 0.79% | +6,531 |
| AXSOME THERAPEUTICS INC(AXSM) | 631,487 | 635,372 | +3,885 | 44,135 | 50,569 | 0.77% | +6,435 |
| ACCOLADE INC | 4,527,923 | 4,507,404 | -20,519 | 47,905 | 54,134 | 0.83% | +6,228 |
| CASTLE BIOSCIENCES INC(CSTL) | 1,228,031 | 1,232,378 | +4,347 | 20,741 | 26,595 | 0.41% | +5,853 |
| COOPER COS INC(COO) | 86,567 | 86,037 | -530 | 27,529 | 32,560 | 0.50% | +5,031 |
| NATERA INC(NTRA) | 257,686 | 256,584 | -1,102 | 11,403 | 16,072 | 0.25% | +4,670 |
| 10X GENOMICS INC(TXG) | 294,432 | 293,173 | -1,259 | 12,145 | 16,406 | 0.25% | +4,261 |
| SAGE THERAPEUTICS INC | 3,513,351 | 3,513,351 | 0 | 72,305 | 76,134 | 1.16% | +3,830 |
| ZAI LAB LTD(ZLAB) | 0 | 135,000 | +135,000 | 0 | 3,714 | 0.06% | +3,714 |
| HCA HEALTHCARE INC(HCA) | 155,643 | 152,178 | -3,465 | 38,285 | 41,192 | 0.63% | +2,906 |
| VERONA PHARMA PLC | 856,358 | 839,996 | -16,362 | 13,959 | 16,699 | 0.26% | +2,740 |
| SI-BONE INC(SIBN) | 0 | 125,200 | +125,200 | 0 | 2,628 | 0.04% | +2,628 |
| ZIMMER BIOMET HOLDINGS INC(ZBH) | 284,888 | 281,088 | -3,800 | 31,970 | 34,208 | 0.52% | +2,238 |
| CENTENE CORP DEL(CNC) | 444,043 | 441,853 | -2,190 | 30,586 | 32,790 | 0.50% | +2,204 |
| BEAM THERAPEUTICS INC(BEAM) | 694,821 | 694,821 | 0 | 16,710 | 18,913 | 0.29% | +2,203 |
| IDEXX LABS INC(IDXX) | 114,441 | 94,110 | -20,331 | 50,042 | 52,236 | 0.80% | +2,194 |
| GLOBUS MED INC(GMED) | 609,615 | 607,772 | -1,843 | 30,267 | 32,388 | 0.50% | +2,121 |
| MERCK & CO INC(MRK) | 291,896 | 290,206 | -1,690 | 30,051 | 31,638 | 0.48% | +1,588 |
| EXACT SCIENCES CORP(EXK) | 1,119,819 | 1,047,786 | -72,033 | 76,394 | 77,515 | 1.19% | +1,121 |
| JOHNSON & JOHNSON(JNJ) | 22,823 | 28,280 | +5,457 | 3,555 | 4,433 | 0.07% | +878 |
| ENCOMPASS HEALTH CORP(EHC) | 0 | 11,900 | +11,900 | 0 | 794 | 0.01% | +794 |
| KARUNA THERAPEUTICS INC | 6,900 | 6,100 | -800 | 1,167 | 1,931 | 0.03% | +764 |
| BLACK DIAMOND THERAPEUTICS I | 8,135,839 | 8,535,839 | +400,000 | 23,350 | 23,986 | 0.37% | +636 |
| ROCKET PHARMACEUTICALS INC(RCKT) | 0 | 21,000 | +21,000 | 0 | 629 | 0.01% | +629 |
| HOLOGIC INC | 290,136 | 289,864 | -272 | 20,135 | 20,711 | 0.32% | +575 |
| VERVE THERAPEUTICS INC | 0 | 39,000 | +39,000 | 0 | 544 | 0.01% | +544 |
| CYTOKINETICS INC(CYTK) | 37,100 | 18,900 | -18,200 | 1,093 | 1,578 | 0.02% | +485 |
| BIOMARIN PHARMACEUTICAL INC(BMRN) | 349,888 | 325,776 | -24,112 | 30,958 | 31,411 | 0.48% | +453 |
| NEVRO CORP | 198,171 | 197,324 | -847 | 3,809 | 4,246 | 0.06% | +438 |
| DAVITA INC(DVA) | 0 | 3,800 | +3,800 | 0 | 398 | 0.01% | +398 |
| LULULEMON ATHLETICA INC(LULU) | 0 | 770 | +770 | 0 | 394 | 0.01% | +394 |
| RECURSION PHARMACEUTICALS IN(RXRX) | 174,085 | 174,557 | +472 | 1,332 | 1,721 | 0.03% | +389 |
| LIFE TIME GROUP HOLDINGS INC(LTH) | 0 | 25,200 | +25,200 | 0 | 380 | 0.01% | +380 |
| NIKE INC(NKE) | 0 | 3,400 | +3,400 | 0 | 369 | 0.01% | +369 |
| BIOMEA FUSION INC(BMEA) | 0 | 25,000 | +25,000 | 0 | 363 | 0.01% | +363 |
| CARDINAL HEALTH INC(CAH) | 0 | 3,500 | +3,500 | 0 | 353 | 0.01% | +353 |
| C4 THERAPEUTICS INC(CCCC) | 0 | 62,000 | +62,000 | 0 | 350 | 0.01% | +350 |
| WW INTL INC(WW) | 0 | 40,000 | +40,000 | 0 | 350 | 0.01% | +350 |
| PFIZER INC(PFE) | 9,555 | 22,868 | +13,313 | 317 | 658 | 0.01% | +341 |
| ABBVIE INC(ABBV) | 4,763 | 6,727 | +1,964 | 710 | 1,042 | 0.02% | +333 |
| VIKING THERAPEUTICS INC(VKTX) | 0 | 17,500 | +17,500 | 0 | 326 | 0.00% | +326 |
| AUTOLUS THERAPEUTICS PLC(AUTL) | 0 | 50,000 | +50,000 | 0 | 322 | 0.00% | +322 |
| CERTARA INC(CERT) | 91,606 | 91,215 | -391 | 1,332 | 1,604 | 0.02% | +273 |
| LABORATORY CORP AMER HLDGS | 6,988 | 7,089 | +101 | 1,405 | 1,611 | 0.02% | +206 |
| XENON PHARMACEUTICALS INC(XENE) | 23,900 | 22,000 | -1,900 | 816 | 1,013 | 0.02% | +197 |
| PROTAGONIST THERAPEUTICS INC | 30,000 | 30,000 | 0 | 500 | 688 | 0.01% | +188 |
| AMNEAL PHARMACEUTICALS INC(AMRX) | 0 | 25,470 | +25,470 | 0 | 155 | 0.00% | +155 |
| VANECK ETF TRUST GOLD MINERS ETF | 33,000 | 33,000 | 0 | 888 | 1,023 | 0.02% | +135 |
| SPDR S&P 500 ETF TR(SPY) | 2,600 | 2,600 | 0 | 1,111 | 1,236 | 0.02% | +124 |
| TENET HEALTHCARE CORP(THC) | 700 | 1,447 | +747 | 46 | 109 | 0.00% | +63 |
| ALPHABET INC(GOOG) | 6,000 | 6,000 | 0 | 791 | 846 | 0.01% | +54 |
| AGILENT TECHNOLOGIES INC(A) | 0 | 363 | +363 | 0 | 50 | 0.00% | +50 |
| QUALCOMM INC(QCOM) | 0 | 347 | +347 | 0 | 50 | 0.00% | +50 |
| NVIDIA CORPORATION(NVDA) | 0 | 99 | +99 | 0 | 49 | 0.00% | +49 |
| ORACLE CORP(ORCL) | 0 | 454 | +454 | 0 | 48 | 0.00% | +48 |
| MICROSOFT CORP(MSFT) | 0 | 122 | +122 | 0 | 46 | 0.00% | +46 |
| INHIBRX INC | 48,800 | 24,600 | -24,200 | 895 | 935 | 0.01% | +39 |
| METTLER TOLEDO INTERNATIONAL(MTD) | 0 | 25 | +25 | 0 | 30 | 0.00% | +30 |
| VANECK ETF TRUST JUNIOR GOLD MINE | 5,000 | 5,000 | 0 | 161 | 190 | 0.00% | +28 |
| CVS HEALTH CORP(CVS) | 35,314 | 31,503 | -3,811 | 2,466 | 2,487 | 0.04% | +22 |
| ZOETIS INC(ZTS) | 6,462 | 5,790 | -672 | 1,124 | 1,143 | 0.02% | +19 |
| EXSCIENTIA PLC | 0 | 1,765 | +1,765 | 0 | 11 | 0.00% | +11 |
| IONQ INC(IONQ) | 0 | 741 | +741 | 0 | 9 | 0.00% | +9 |
| GRUPO AEROPORTUARIO DEL SURE | 135 | 0 | -135 | 0 | 0 | — | -0 |
| TAIWAN SEMICONDUCTOR MFG LTD(TSM) | 1,089 | 0 | -1,089 | 2 | 0 | — | -2 |