Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| AMICUS THERAPEUTICS INC COM | 0 | 10,735,195 | +10,735,195 | 0 | 152,869 | 2.90% | +152,869 |
| REVOLUTION MEDICINES INC(RVMD) | 5,573,838 | 5,005,719 | -568,119 | 260,298 | 398,706 | 7.56% | +138,407 |
| VIRIDIAN THERAPEUTICS INC(VRDN) | 0 | 4,358,527 | +4,358,527 | 0 | 135,637 | 2.57% | +135,637 |
| VERTEX PHARMACEUTICALS INC(VRTX) | 505,805 | 681,120 | +175,315 | 198,093 | 308,793 | 5.85% | +110,699 |
| NUVALENT INC | 0 | 1,037,468 | +1,037,468 | 0 | 104,359 | 1.98% | +104,359 |
| KRYSTAL BIOTECH INC(KRYS) | 1,312 | 410,323 | +409,011 | 232 | 101,161 | 1.92% | +100,929 |
| AVIDITY BIOSCIENCES INC | 2,152,862 | 2,630,969 | +478,107 | 93,800 | 189,772 | 3.60% | +95,972 |
| VERA THERAPEUTICS INC(VERA) | 0 | 1,698,152 | +1,698,152 | 0 | 85,994 | 1.63% | +85,994 |
| SCHOLAR ROCK HLDG CORP(SRRK) | 3,244,537 | 4,056,592 | +812,055 | 120,827 | 178,693 | 3.39% | +57,866 |
| JADE BIOSCIENCES INC | 0 | 3,341,103 | +3,341,103 | 0 | 51,553 | 0.98% | +51,553 |
| MAZE THERAPEUTICS INC(MAZE) | 0 | 887,708 | +887,708 | 0 | 36,778 | 0.70% | +36,778 |
| TANGO THERAPEUTICS INC(TNGX) | 0 | 3,927,670 | +3,927,670 | 0 | 34,799 | 0.66% | +34,799 |
| RELAY THERAPEUTICS INC(RLAY) | 8,345,610 | 8,345,364 | -246 | 43,564 | 70,602 | 1.34% | +27,038 |
| INTUITIVE SURGICAL INC | 0 | 322,028 | +322,028 | 0 | 182,384 | 3.46% | +182,384 |
| GLAUKOS CORP(GKOS) | 0 | 261,935 | +261,935 | 0 | 29,575 | 0.56% | +29,575 |
| EDWARDS LIFESCIENCES CORP | 896,633 | 1,043,096 | +146,463 | 69,731 | 88,924 | 1.69% | +19,193 |
| IDEXX LABS INC(IDXX) | 76,587 | 94,539 | +17,952 | 48,931 | 63,958 | 1.21% | +15,028 |
| JOHNSON & JOHNSON(JNJ) | 74,807 | 126,800 | +51,993 | 13,871 | 26,241 | 0.50% | +12,371 |
| DANAHER CORPORATION(DHR) | 163,876 | 194,633 | +30,757 | 32,490 | 44,555 | 0.84% | +12,065 |
| ANNEXON INC(ANNX) | 5,157,290 | 5,157,290 | 0 | 15,730 | 25,890 | 0.49% | +10,160 |
| MERCK & CO INC(MRK) | 34,739 | 92,117 | +57,378 | 2,916 | 9,696 | 0.18% | +6,781 |
| CELLDEX THERAPEUTICS INC NEW(CLDX) | 3,557,669 | 3,617,669 | +60,000 | 92,037 | 98,256 | 1.86% | +6,219 |
| ELI LILLY & CO(LLY) | 0 | 34,003 | +34,003 | 0 | 36,542 | 0.69% | +36,542 |
| MEDLINE INC(MDLN) | 0 | 117,720 | +117,720 | 0 | 4,944 | 0.09% | +4,944 |
| INSPIRE MED SYS INC(INSP) | 0 | 100,761 | +100,761 | 0 | 9,293 | 0.18% | +9,293 |
| PENUMBRA INC(PEN) | 0 | 135,395 | +135,395 | 0 | 42,096 | 0.80% | +42,096 |
| CVS HEALTH CORP(CVS) | 51,199 | 109,058 | +57,859 | 3,860 | 8,655 | 0.16% | +4,795 |
| GLOBUS MED INC(GMED) | 0 | 262,683 | +262,683 | 0 | 22,935 | 0.43% | +22,935 |
| ALIGN TECHNOLOGY INC | 0 | 141,474 | +141,474 | 0 | 22,091 | 0.42% | +22,091 |
| COOPER COS INC(COO) | 0 | 291,959 | +291,959 | 0 | 23,929 | 0.45% | +23,929 |
| DEXCOM INC(DXCM) | 0 | 847,405 | +847,405 | 0 | 56,242 | 1.07% | +56,242 |
| WAYSTAR HLDG CORP(WAY) | 0 | 241,734 | +241,734 | 0 | 7,917 | 0.15% | +7,917 |
| ROIVANT SCIENCES LTD(ROIV) | 0 | 108,039 | +108,039 | 0 | 2,344 | 0.04% | +2,344 |
| ADAPTIVE BIOTECHNOLOGIES COR(ADPT) | 168,476 | 298,090 | +129,614 | 2,520 | 4,841 | 0.09% | +2,321 |
| REGENERON PHARMACEUTICALS(REGN) | 0 | 13,928 | +13,928 | 0 | 10,751 | 0.20% | +10,751 |
| AVANTOR INC(AVTR) | 103,362 | 276,266 | +172,904 | 1,290 | 3,166 | 0.06% | +1,876 |
| AMGEN INC(AMGN) | 0 | 18,489 | +18,489 | 0 | 6,052 | 0.11% | +6,052 |
| TEVA PHARMACEUTICAL INDS LTD(TEVA) | 424,056 | 327,863 | -96,193 | 8,566 | 10,233 | 0.19% | +1,667 |
| 10X GENOMICS INC(TXG) | 313,836 | 322,060 | +8,224 | 3,669 | 5,253 | 0.10% | +1,584 |
| BRISTOL-MYERS SQUIBB CO(BMY) | 47,613 | 67,082 | +19,469 | 2,147 | 3,618 | 0.07% | +1,471 |
| MEDTRONIC PLC(MDT) | 0 | 766,592 | +766,592 | 0 | 73,639 | 1.40% | +73,639 |
| STRUCTURE THERAPEUTICS INC | 315,857 | 145,167 | -170,690 | 8,844 | 10,096 | 0.19% | +1,252 |
| CENTENE CORP DEL(CNC) | 281,949 | 273,674 | -8,275 | 10,060 | 11,262 | 0.21% | +1,202 |
| PFIZER INC(PFE) | 0 | 56,847 | +56,847 | 0 | 1,415 | 0.03% | +1,415 |
| COMPASS PATHWAYS PLC(CMPS) | 0 | 142,243 | +142,243 | 0 | 981 | 0.02% | +981 |
| GILEAD SCIENCES INC(GILD) | 49,893 | 52,752 | +2,859 | 5,538 | 6,475 | 0.12% | +937 |
| BETA BIONICS INC | 64,283 | 72,285 | +8,002 | 1,277 | 2,203 | 0.04% | +925 |
| BROOKDALE SR LIVING INC(BKD) | 104,665 | 167,444 | +62,779 | 887 | 1,807 | 0.03% | +920 |
| BILLIONTOONE INC | 0 | 10,589 | +10,589 | 0 | 867 | 0.02% | +867 |
| NEWAMSTERDAM PHARMA COMPANY ORDINARY SHARES | 14,611 | 36,336 | +21,725 | 416 | 1,275 | 0.02% | +859 |
| BIONTECH SE(BNTX) | 0 | 43,755 | +43,755 | 0 | 4,165 | 0.08% | +4,165 |
| UNITED THERAPEUTICS CORP DEL(UTHR) | 2,640 | 3,895 | +1,255 | 1,107 | 1,898 | 0.04% | +791 |
| BRIDGEBIO PHARMA INC(BBIO) | 20,356 | 24,111 | +3,755 | 1,057 | 1,844 | 0.03% | +787 |
| ARROWHEAD PHARMACEUTICALS IN(ARWR) | 0 | 11,550 | +11,550 | 0 | 767 | 0.01% | +767 |
| ILLUMINA INC(ILMN) | 0 | 22,940 | +22,940 | 0 | 3,009 | 0.06% | +3,009 |
| ALIBABA GROUP HLDG LTD(BABA) | 0 | 4,700 | +4,700 | 0 | 689 | 0.01% | +689 |
| ARISTA NETWORKS INC(ANET) | 0 | 4,800 | +4,800 | 0 | 629 | 0.01% | +629 |
| MASTERCARD INCORPORATED(MA) | 0 | 1,100 | +1,100 | 0 | 628 | 0.01% | +628 |
| CISCO SYS INC(CSCO) | 0 | 8,000 | +8,000 | 0 | 616 | 0.01% | +616 |
| NVIDIA CORPORATION(NVDA) | 702 | 3,933 | +3,231 | 131 | 734 | 0.01% | +603 |
| MADRIGAL PHARMACEUTICALS INC(MDGL) | 2,393 | 2,884 | +491 | 1,098 | 1,679 | 0.03% | +582 |
| PROCTER AND GAMBLE CO(PG) | 0 | 3,900 | +3,900 | 0 | 559 | 0.01% | +559 |
| MICROSOFT CORP(MSFT) | 203 | 1,282 | +1,079 | 105 | 620 | 0.01% | +515 |
| APPLE INC(AAPL) | 1,609 | 3,320 | +1,711 | 410 | 903 | 0.02% | +493 |
| VISA INC(V) | 0 | 1,400 | +1,400 | 0 | 491 | 0.01% | +491 |
| BLACKROCK INC(BLK) | 0 | 450 | +450 | 0 | 482 | 0.01% | +482 |
| CYTOKINETICS INC(CYTK) | 2,100 | 9,225 | +7,125 | 115 | 586 | 0.01% | +471 |
| LULULEMON ATHLETICA INC(LULU) | 0 | 2,240 | +2,240 | 0 | 465 | 0.01% | +465 |
| PALANTIR TECHNOLOGIES INC(PLTR) | 0 | 2,500 | +2,500 | 0 | 444 | 0.01% | +444 |
| ADOBE INC(ADBE) | 0 | 1,200 | +1,200 | 0 | 420 | 0.01% | +420 |
| AMAZON COM INC(AMZN) | 1,812 | 3,541 | +1,729 | 398 | 817 | 0.02% | +419 |
| VIKING THERAPEUTICS INC(VKTX) | 76,082 | 68,665 | -7,417 | 1,999 | 2,416 | 0.05% | +416 |
| NEOGENOMICS INC(NEO) | 0 | 278,286 | +278,286 | 0 | 3,273 | 0.06% | +3,273 |
| ACCENTURE PLC IRELAND SHS CLASS A | 0 | 1,500 | +1,500 | 0 | 402 | 0.01% | +402 |
| ALPHABET INC(GOOG) | 1,082 | 2,066 | +984 | 263 | 647 | 0.01% | +384 |
| PTC THERAPEUTICS INC(PTCT) | 2,530 | 6,763 | +4,233 | 155 | 514 | 0.01% | +358 |
| JD.COM INC(JD) | 0 | 11,000 | +11,000 | 0 | 316 | 0.01% | +316 |
| CORCEPT THERAPEUTICS INC(CORT) | 1,227 | 10,495 | +9,268 | 102 | 365 | 0.01% | +263 |
| ASCENDIS PHARMA A/S(ASND) | 24,903 | 24,330 | -573 | 4,951 | 5,188 | 0.10% | +237 |
| META PLATFORMS INC(META) | 400 | 800 | +400 | 294 | 528 | 0.01% | +234 |
| ICON PLC(ICLR) | 24,247 | 24,560 | +313 | 4,243 | 4,475 | 0.08% | +232 |
| CRINETICS PHARMACEUTICALS IN(CRNX) | 0 | 4,040 | +4,040 | 0 | 188 | 0.00% | +188 |
| GUARDANT HEALTH INC(GH) | 1,953 | 3,004 | +1,051 | 122 | 307 | 0.01% | +185 |
| IDEAYA BIOSCIENCES INC(IDYA) | 0 | 4,942 | +4,942 | 0 | 171 | 0.00% | +171 |
| CERTARA INC(CERT) | 0 | 99,442 | +99,442 | 0 | 876 | 0.02% | +876 |
| TRAVERE THERAPEUTICS INC(TVTX) | 0 | 3,827 | +3,827 | 0 | 146 | 0.00% | +146 |
| CG ONCOLOGY INC(CGON) | 0 | 3,095 | +3,095 | 0 | 129 | 0.00% | +129 |
| DENALI THERAPEUTICS INC(DNLI) | 0 | 7,138 | +7,138 | 0 | 118 | 0.00% | +118 |
| APELLIS PHARMACEUTICALS INC COM | 0 | 4,210 | +4,210 | 0 | 106 | 0.00% | +106 |
| CRISPR THERAPEUTICS AG(CRSP) | 0 | 1,880 | +1,880 | 0 | 99 | 0.00% | +99 |
| OLEMA PHARMACEUTICALS INC(OLMA) | 0 | 3,902 | +3,902 | 0 | 98 | 0.00% | +98 |
| TREVI THERAPEUTICS INC(TRVI) | 0 | 7,603 | +7,603 | 0 | 95 | 0.00% | +95 |
| TYRA BIOSCIENCES INC(TYRA) | 0 | 3,143 | +3,143 | 0 | 83 | 0.00% | +83 |
| ORIC PHARMACEUTICALS INC(ORIC) | 0 | 9,706 | +9,706 | 0 | 79 | 0.00% | +79 |
| PROTAGONIST THERAPEUTICS INC | 20,581 | 16,543 | -4,038 | 1,367 | 1,445 | 0.03% | +78 |
| ASTRAZENECA PLC(AZN) | 35,644 | 30,431 | -5,213 | 2,735 | 2,798 | 0.05% | +63 |
| ULTRAGENYX PHARMACEUTICAL IN(RARE) | 0 | 2,580 | +2,580 | 0 | 59 | 0.00% | +59 |
| ROYALTY PHARMA PLC(RPRX) | 12,961 | 13,201 | +240 | 457 | 510 | 0.01% | +53 |
| SPDR S&P 500 ETF TR(SPY) | 3,100 | 3,100 | 0 | 2,065 | 2,114 | 0.04% | +49 |
| GE HEALTHCARE TECHNOLOGIES I(GEHC) | 0 | 424,514 | +424,514 | 0 | 34,819 | 0.66% | +34,819 |