Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Revolution Medicines, Inc.(RVMD) | 5,573,838 | 5,005,719 | -568,119 | $260.30M | $398.71M | 7.56% | +$138.41M |
| argenx SEADR(ARGX) | 546,328 | 461,854 | -84,474 | $402.95M | $388.40M | 7.36% | -$14.55M |
| Ionis Pharmaceuticals, Inc.(IONS) | 6,244,451 | 4,802,199 | -1,442,252 | $408.51M | $379.90M | 7.20% | -$28.61M |
| Vertex Pharmaceuticals Incorporated(VRTX) | 505,805 | 681,120 | +175,315 | $198.09M | $308.79M | 5.85% | +$110.70M |
| Neurocrine Biosciences, Inc.(NBIX) | 1,763,105 | 1,703,304 | -59,801 | $247.50M | $241.58M | 4.58% | -$5.93M |
| Avidity Biosciences Inc | 2,152,862 | 2,630,969 | +478,107 | $93.80M | $189.77M | 3.60% | +$95.97M |
| Intuitive Surgical, Inc.(ISRG) | 348,626 | 322,028 | -26,598 | $155.92M | $182.38M | 3.46% | +$26.47M |
| Scholar Rock Holding Corporation(SRRK) | 3,244,537 | 4,056,592 | +812,055 | $120.83M | $178.69M | 3.39% | +$57.87M |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 446,524 | 445,903 | -621 | $203.61M | $177.31M | 3.36% | -$26.30M |
| Abbott Labs | 1,478,563 | 1,316,915 | -161,648 | $198.04M | $165.00M | 3.13% | -$33.04M |
| Amicus Therapeutics Inc COM | 0 | 10,735,195 | +10,735,195 | $0 | $152.87M | 2.90% | +$152.87M |
| Boston Scientific Corporation(BSX) | 1,659,849 | 1,559,606 | -100,243 | $162.05M | $148.71M | 2.82% | -$13.34M |
| Viridian Therapeutics, Inc.(VRDN) | 0 | 4,358,527 | +4,358,527 | $0 | $135.64M | 2.57% | +$135.64M |
| Stryker Corporation(SYK) | 451,096 | 360,577 | -90,519 | $166.76M | $126.73M | 2.40% | -$40.02M |
| Nuvalent Inc | 0 | 1,037,468 | +1,037,468 | $0 | $104.36M | 1.98% | +$104.36M |
| Krystal Biotech, Inc.(KRYS) | 1,312 | 410,323 | +409,011 | $231.6K | $101.16M | 1.92% | +$100.93M |
| Celldex Therapeutics, Inc.(CLDX) | 3,557,669 | 3,617,669 | +60,000 | $92.04M | $98.26M | 1.86% | +$6.22M |
| Immunocore Holdings plcADS(IMCR) | 2,796,803 | 2,796,803 | 0 | $101.61M | $97.08M | 1.84% | -$4.53M |
| Edwards Lifesciences Corp | 896,633 | 1,043,096 | +146,463 | $69.73M | $88.92M | 1.69% | +$19.19M |
| Vera Therapeutics, Inc.CL A(VERA) | 0 | 1,698,152 | +1,698,152 | $0 | $85.99M | 1.63% | +$85.99M |
| Medtronic plcSHS(MDT) | 759,861 | 766,592 | +6,731 | $72.37M | $73.64M | 1.40% | +$1.27M |
| Relay Therapeutics, Inc.(RLAY) | 8,345,610 | 8,345,364 | -246 | $43.56M | $70.60M | 1.34% | +$27.04M |
| IDEXX Laboratories, Inc.(IDXX) | 76,587 | 94,539 | +17,952 | $48.93M | $63.96M | 1.21% | +$15.03M |
| UnitedHealth Group Incorporated(UNH) | 170,057 | 175,169 | +5,112 | $58.72M | $57.83M | 1.10% | -$895.6K |
| DexCom, Inc.(DXCM) | 786,118 | 847,405 | +61,287 | $52.90M | $56.24M | 1.07% | +$3.34M |
| Insulet Corporation(PODD) | 212,005 | 186,699 | -25,306 | $65.45M | $53.07M | 1.01% | -$12.38M |
| Becton, Dickinson and Company(BDX) | 296,894 | 265,662 | -31,232 | $55.57M | $51.56M | 0.98% | -$4.01M |
| Jade Biosciences Inc | 0 | 3,341,103 | +3,341,103 | $0 | $51.55M | 0.98% | +$51.55M |
| Danaher Corporation(DHR) | 163,876 | 194,633 | +30,757 | $32.49M | $44.56M | 0.84% | +$12.07M |
| Penumbra, Inc.(PEN) | 146,895 | 135,395 | -11,500 | $37.21M | $42.10M | 0.80% | +$4.88M |
| ResMed Inc.(RMD) | 164,834 | 161,214 | -3,620 | $45.12M | $38.83M | 0.74% | -$6.29M |
| Edgewise Therapeutics, Inc.(EWTX) | 2,775,997 | 1,528,518 | -1,247,479 | $45.03M | $37.93M | 0.72% | -$7.10M |
| Thermo Fisher Scientific Inc.(TMO) | 106,185 | 65,077 | -41,108 | $51.50M | $37.71M | 0.71% | -$13.79M |
| Maze Therapeutics, Inc.(MAZE) | 0 | 887,708 | +887,708 | $0 | $36.78M | 0.70% | +$36.78M |
| Eli Lilly and Company(LLY) | 40,514 | 34,003 | -6,511 | $30.91M | $36.54M | 0.69% | +$5.63M |
| GE HealthCare Technologies Inc.(GEHC) | 463,063 | 424,514 | -38,549 | $34.78M | $34.82M | 0.66% | +$42.6K |
| Tango Therapeutics, Inc.(TNGX) | 0 | 3,927,670 | +3,927,670 | $0 | $34.80M | 0.66% | +$34.80M |
| AbbVie Inc.(ABBV) | 170,870 | 134,859 | -36,011 | $39.56M | $30.81M | 0.58% | -$8.75M |
| The Cigna Group(CI) | 122,486 | 110,013 | -12,473 | $35.31M | $30.28M | 0.57% | -$5.03M |
| Glaukos Corporation(GKOS) | 55,926 | 261,935 | +206,009 | $4.56M | $29.58M | 0.56% | +$25.01M |
| Johnson & Johnson(JNJ) | 74,807 | 126,800 | +51,993 | $13.87M | $26.24M | 0.50% | +$12.37M |
| Annexon, Inc.(ANNX) | 5,157,290 | 5,157,290 | 0 | $15.73M | $25.89M | 0.49% | +$10.16M |
| STERIS plcSHS USD(STE) | 118,112 | 101,705 | -16,407 | $29.23M | $25.78M | 0.49% | -$3.44M |
| Wave Life Sciences, Inc.SHS(WVE) | 4,094,458 | 1,490,518 | -2,603,940 | $29.97M | $25.34M | 0.48% | -$4.63M |
| Elevance Health, Inc.(ELV) | 104,971 | 69,645 | -35,326 | $33.92M | $24.41M | 0.46% | -$9.50M |
| The Cooper Companies, Inc.(COO) | 292,265 | 291,959 | -306 | $20.04M | $23.93M | 0.45% | +$3.89M |
| Globus Medical, Inc.CL A(GMED) | 326,867 | 262,683 | -64,184 | $18.72M | $22.93M | 0.43% | +$4.22M |
| Align Technology Inc | 144,676 | 141,474 | -3,202 | $18.12M | $22.09M | 0.42% | +$3.97M |
| Zimmer Biomet Holdings, Inc.(ZBH) | 245,202 | 238,680 | -6,522 | $24.15M | $21.46M | 0.41% | -$2.69M |
| McKesson Corporation(MCK) | 37,957 | 25,098 | -12,859 | $29.32M | $20.59M | 0.39% | -$8.74M |
| HCA Healthcare, Inc.(HCA) | 65,607 | 43,906 | -21,701 | $27.96M | $20.50M | 0.39% | -$7.46M |
| Humana Inc.(HUM) | 76,310 | 73,081 | -3,229 | $19.85M | $18.72M | 0.35% | -$1.14M |
| Veeva Systems Inc.CL A(VEEV) | 97,506 | 80,529 | -16,977 | $29.05M | $17.98M | 0.34% | -$11.07M |
| PROCEPT BioRobotics Corporation(PRCT) | 463,404 | 515,430 | +52,026 | $16.54M | $16.22M | 0.31% | -$323.5K |
| Natera, Inc.(NTRA) | 91,818 | 56,036 | -35,782 | $14.78M | $12.84M | 0.24% | -$1.94M |
| Masimo Corp | 96,968 | 97,285 | +317 | $14.31M | $12.65M | 0.24% | -$1.65M |
| TransMedics Group, Inc.(TMDX) | 116,968 | 97,885 | -19,083 | $13.12M | $11.91M | 0.23% | -$1.22M |
| Centene Corporation(CNC) | 281,949 | 273,674 | -8,275 | $10.06M | $11.26M | 0.21% | +$1.20M |
| Regeneron Pharmaceuticals, Inc.(REGN) | 15,057 | 13,928 | -1,129 | $8.47M | $10.75M | 0.20% | +$2.28M |
| Privia Health Group, Inc.(PRVA) | 666,177 | 448,163 | -218,014 | $16.59M | $10.63M | 0.20% | -$5.96M |
| Teva Pharmaceutical Industries LimitedADS(TEVA) | 424,056 | 327,863 | -96,193 | $8.57M | $10.23M | 0.19% | +$1.67M |
| Structure Therapeutics IncADS | 315,857 | 145,167 | -170,690 | $8.84M | $10.10M | 0.19% | +$1.25M |
| Merck & Co., Inc.(MRK) | 34,739 | 92,117 | +57,378 | $2.92M | $9.70M | 0.18% | +$6.78M |
| IQVIA Holdings Inc.(IQV) | 52,898 | 41,267 | -11,631 | $10.05M | $9.30M | 0.18% | -$745.5K |
| Inspire Medical Systems, Inc.(INSP) | 58,648 | 100,761 | +42,113 | $4.35M | $9.29M | 0.18% | +$4.94M |
| CVS Health Corporation(CVS) | 51,199 | 109,058 | +57,859 | $3.86M | $8.65M | 0.16% | +$4.79M |
| CareDx, Inc.(CDNA) | 572,956 | 431,070 | -141,886 | $8.33M | $8.12M | 0.15% | -$209.4K |
| Molina Healthcare, Inc.(MOH) | 90,985 | 46,626 | -44,359 | $17.41M | $8.09M | 0.15% | -$9.32M |
| Tenet Healthcare Corporation(THC) | 40,372 | 40,239 | -133 | $8.20M | $8.00M | 0.15% | -$200.8K |
| Waystar Holding Corp.(WAY) | 129,913 | 241,734 | +111,821 | $4.93M | $7.92M | 0.15% | +$2.99M |
| Gilead Sciences, Inc.(GILD) | 49,893 | 52,752 | +2,859 | $5.54M | $6.47M | 0.12% | +$936.7K |
| Amgen Inc.(AMGN) | 14,988 | 18,489 | +3,501 | $4.23M | $6.05M | 0.11% | +$1.82M |
| 10x Genomics, Inc.CL A(TXG) | 313,836 | 322,060 | +8,224 | $3.67M | $5.25M | 0.10% | +$1.58M |
| Ascendis Pharma A/SADR(ASND) | 24,903 | 24,330 | -573 | $4.95M | $5.19M | 0.10% | +$237.2K |
| Axsome Therapeutics, Inc.(AXSM) | 52,335 | 27,600 | -24,735 | $6.36M | $5.04M | 0.10% | -$1.32M |
| Medline Inc.CL A(MDLN) | 0 | 117,720 | +117,720 | $0 | $4.94M | 0.09% | +$4.94M |
| Adaptive Biotechnologies Corporation(ADPT) | 168,476 | 298,090 | +129,614 | $2.52M | $4.84M | 0.09% | +$2.32M |
| ICON Public Limited CompanySHS(ICLR) | 24,247 | 24,560 | +313 | $4.24M | $4.48M | 0.08% | +$232.1K |
| BioNTech SEADS(BNTX) | 33,955 | 43,755 | +9,800 | $3.35M | $4.17M | 0.08% | +$816.8K |
| BioMarin Pharmaceutical Inc.(BMRN) | 101,033 | 65,008 | -36,025 | $5.47M | $3.86M | 0.07% | -$1.61M |
| Bristol-Myers Squibb Company(BMY) | 47,613 | 67,082 | +19,469 | $2.15M | $3.62M | 0.07% | +$1.47M |
| BrightSpring Health Services, Inc.(BTSG) | 190,524 | 92,095 | -98,429 | $5.63M | $3.45M | 0.07% | -$2.18M |
| NeoGenomics, Inc.(NEO) | 370,198 | 278,286 | -91,912 | $2.86M | $3.27M | 0.06% | +$414.7K |
| Avantor, Inc.(AVTR) | 103,362 | 276,266 | +172,904 | $1.29M | $3.17M | 0.06% | +$1.88M |
| Phreesia, Inc.(PHR) | 313,057 | 183,213 | -129,844 | $7.36M | $3.10M | 0.06% | -$4.26M |
| Beam Therapeutics Inc.(BEAM) | 2,889,288 | 111,510 | -2,777,778 | $70.12M | $3.09M | 0.06% | -$67.03M |
| Kestra Med Technologies LtdSHS SHS | 128,711 | 115,755 | -12,956 | $3.06M | $3.07M | 0.06% | +$11.7K |
| Illumina, Inc.(ILMN) | 23,797 | 22,940 | -857 | $2.26M | $3.01M | 0.06% | +$748.8K |
| Omada Health, Inc.(OMDA) | 251,791 | 177,897 | -73,894 | $5.57M | $2.81M | 0.05% | -$2.76M |
| AstraZeneca PLCADR(AZN) | 35,644 | 30,431 | -5,213 | $2.73M | $2.80M | 0.05% | +$62.9K |
| Insmed Incorporated(INSM) | 20,251 | 13,915 | -6,336 | $2.92M | $2.42M | 0.05% | -$494.6K |
| Viking Therapeutics, Inc.(VKTX) | 76,082 | 68,665 | -7,417 | $2.00M | $2.42M | 0.05% | +$416.2K |
| Roivant Sciences Ltd.SHS(ROIV) | 0 | 108,039 | +108,039 | $0 | $2.34M | 0.04% | +$2.34M |
| Beta Bionics, Inc.(BBNX) | 64,283 | 72,285 | +8,002 | $1.28M | $2.20M | 0.04% | +$925.2K |
| State Street SPDR S&P 500 ETF TrustTR UNIT(SPY) | 3,100 | 3,100 | 0 | $2.07M | $2.11M | 0.04% | +$48.8K |
| Encompass Health Corporation(EHC) | 122,958 | 19,089 | -103,869 | $15.62M | $2.03M | 0.04% | -$13.59M |
| United Therapeutics Corporation(UTHR) | 2,640 | 3,895 | +1,255 | $1.11M | $1.90M | 0.04% | +$791.1K |
| BridgeBio Pharma, Inc.(BBIO) | 20,356 | 24,111 | +3,755 | $1.06M | $1.84M | 0.03% | +$787.0K |
| Brookdale Senior Living Inc.(BKD) | 104,665 | 167,444 | +62,779 | $886.5K | $1.81M | 0.03% | +$920.2K |
| SI-BONE, Inc.(SIBN) | 298,857 | 90,331 | -208,526 | $4.40M | $1.78M | 0.03% | -$2.62M |