Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2023 ▲▼ | Q1 2024 ▲▼ | Change ▲▼ | Q4 2023 ▲▼ | Q1 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Sinovac Biotech Ltd.(SVA) | 0 | 11,800,000 | +11,800,000 | 0 | 76,346 | 6.00% | +76,346 |
| Geron Corp(GERN) | 24,143,681 | 27,225,292 | +3,081,611 | 50,943 | 89,843 | 7.06% | +38,900 |
| Dyne Therapeutics Inc(DYN) | 1,035,136 | 1,635,136 | +600,000 | 13,767 | 46,422 | 3.65% | +32,654 |
| Soleno Therapeutics Inc | 8,418,093 | 8,418,093 | 0 | 338,828 | 360,294 | 28.31% | +21,466 |
| Adverum Biotechnologies, Inc. | 0 | 1,500,000 | +1,500,000 | 0 | 21,210 | 1.67% | +21,210 |
| Silence Therapeutics PLC | 510,204 | 1,105,454 | +595,250 | 8,862 | 23,878 | 1.88% | +15,016 |
| Regulus Therapeutics Inc | 0 | 5,000,000 | +5,000,000 | 0 | 14,400 | 1.13% | +14,400 |
| Astria Therapeutics Inc | 2,482,727 | 2,329,027 | -153,700 | 19,067 | 32,781 | 2.58% | +13,714 |
| Avadel Pharmaceuticals PLC | 4,096,428 | 3,972,099 | -124,329 | 57,842 | 67,089 | 5.27% | +9,247 |
| Q32 Bio Inc. | 0 | 370,068 | +370,068 | 0 | 6,306 | 0.50% | +6,306 |
| Verastem Inc | 1,538,461 | 1,538,461 | 0 | 12,523 | 18,154 | 1.43% | +5,631 |
| Engene Holdings Inc. COM | 678,705 | 678,705 | 0 | 6,264 | 11,504 | 0.90% | +5,240 |
| Alpine Immune Sciences Inc | 819,275 | 520,505 | -298,770 | 15,615 | 20,794 | 1.63% | +5,179 |
| Sera Prognostics Inc | 1,650,440 | 1,650,440 | 0 | 9,870 | 15,019 | 1.18% | +5,149 |
| Delcath Systems, Inc. | 855,191 | 1,666,746 | +811,555 | 3,558 | 7,950 | 0.62% | +4,393 |
| Crinetics Pharmaceuticals Inc(CRNX) | 350,000 | 350,000 | 0 | 12,453 | 16,384 | 1.29% | +3,931 |
| Rezolute Inc | 3,242,842 | 2,797,704 | -445,138 | 3,219 | 7,134 | 0.56% | +3,916 |
| Oric Pharmaceuticals Inc(ORIC) | 849,681 | 849,681 | 0 | 7,817 | 11,683 | 0.92% | +3,866 |
| Harmony Biosciences Holdings Inc(HRMY) | 2,606,247 | 2,606,247 | 0 | 84,182 | 87,518 | 6.88% | +3,336 |
| Instil Bio Inc | 624,340 | 624,338 | -2 | 4,757 | 6,743 | 0.53% | +1,985 |
| Cogent Biosciences Inc(COGT) | 2,244,941 | 2,244,941 | 0 | 13,200 | 15,086 | 1.19% | +1,886 |
| Unicycive Therapeutics | 3,470,152 | 3,470,152 | 0 | 3,011 | 4,789 | 0.38% | +1,778 |
| Compass Therapeutics Inc | 3,556,023 | 3,556,023 | 0 | 5,547 | 7,041 | 0.55% | +1,494 |
| Aligos Therapeutics Inc | 3,547,030 | 3,547,030 | 0 | 2,355 | 3,476 | 0.27% | +1,121 |
| Bolt Therapeutics Inc | 3,521,291 | 3,521,291 | 0 | 3,944 | 4,930 | 0.39% | +986 |
| Genetron Holdings Ltd | 2,708,056 | 2,708,056 | 0 | 9,966 | 10,900 | 0.86% | +934 |
| Savara Inc(SVRA) | 2,088,323 | 2,088,323 | 0 | 9,815 | 10,400 | 0.82% | +585 |
| Terns Pharmaceuticals Inc | 6,657,992 | 6,657,992 | 0 | 43,210 | 43,676 | 3.43% | +466 |
| Codexis, Inc | 388,144 | 388,144 | 0 | 1,184 | 1,355 | 0.11% | +171 |
| Aadi Bioscience Inc | 509,572 | 509,572 | 0 | 1,029 | 1,192 | 0.09% | +163 |
| Precision Biosciences Inc | 0 | 4,675 | +4,675 | 0 | 63 | 0.00% | +63 |
| Precision Biosciences Inc | 140,255 | 0 | -140,255 | 51 | 0 | — | -51 |
| Homology Medicines, Inc. | 370,068 | 0 | -370,068 | 225 | 0 | — | -225 |
| DBV Technologies SA | 2,708,875 | 2,708,875 | 0 | 2,581 | 2,029 | 0.16% | -552 |
| Compass Pathway PLC(CMPS) | 1,608,000 | 1,608,000 | 0 | 14,070 | 13,379 | 1.05% | -691 |
| IO Biotech Inc | 6,173,439 | 6,173,439 | 0 | 11,606 | 10,680 | 0.84% | -926 |
| Tourmaline Bio Inc. | 591,882 | 591,882 | 0 | 15,495 | 13,554 | 1.07% | -1,941 |
| Zai Lab Ltd(ZLAB) | 411,677 | 531,198 | +119,521 | 11,251 | 8,510 | 0.67% | -2,741 |
| Arrowhead Pharmaceuticals Inc(ARWR) | 137,411 | 0 | -137,411 | 4,205 | 0 | — | -4,205 |
| Allakos Inc | 2,988,000 | 2,988,000 | 0 | 8,157 | 3,765 | 0.30% | -4,392 |
| Olema Pharmaceuticals Inc(OLMA) | 1,873,704 | 1,873,704 | 0 | 26,288 | 21,210 | 1.67% | -5,078 |
| Iovance Biotherapeutics Inc(IOVA) | 655,057 | 0 | -655,057 | 5,326 | 0 | — | -5,326 |
| Rayzebio Inc | 110,581 | 0 | -110,581 | 6,875 | 0 | — | -6,875 |
| Viridian Therapeutics Inc(VRDN) | 1,678,207 | 1,678,207 | 0 | 36,551 | 29,385 | 2.31% | -7,166 |
| Pharvaris NV COM | 285,000 | 0 | -285,000 | 7,994 | 0 | — | -7,994 |
| KalVista Pharmaceuticals Inc. | 856,008 | 0 | -856,008 | 10,486 | 0 | — | -10,486 |
| Apogee Therapeutics Inc(APGE) | 400,000 | 0 | -400,000 | 11,176 | 0 | — | -11,176 |
| Tarsus Pharmaceuticals Inc(TARS) | 1,784,006 | 565,550 | -1,218,456 | 36,126 | 20,558 | 1.62% | -15,568 |
| ALX Oncology Holdings Inc | 4,220,048 | 4,220,048 | 0 | 62,837 | 47,054 | 3.70% | -15,783 |
| Verona Pharma PLC | 4,249,918 | 3,610,177 | -639,741 | 84,488 | 58,088 | 4.56% | -26,401 |
| Icosavax, Inc. | 1,704,568 | 0 | -1,704,568 | 26,864 | 0 | — | -26,864 |
| Gracell Biotechnologies Inc | 9,546,485 | 0 | -9,546,485 | 95,847 | 0 | — | -95,847 |