Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Cullinan Therapeutics, Inc.(CGEM) | 7,648,268 | 7,648,268 | 0 | $45.35M | $79.16M | 9.06% | +$33.81M |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 100,415 | 96,780 | -3,635 | $46.06M | $56.36M | 6.45% | +$10.30M |
| Liquidia Corporation(LQDA) | 200,000 | 1,400,869 | +1,200,869 | $4.55M | $48.32M | 5.53% | +$43.77M |
| Trevi Therapeutics, Inc.(TRVI) | 3,406,955 | 3,287,087 | -119,868 | $31.17M | $41.15M | 4.71% | +$9.98M |
| Edgewise Therapeutics, Inc.(EWTX) | 1,720,741 | 1,655,256 | -65,485 | $27.91M | $41.08M | 4.70% | +$13.16M |
| Revolution Medicines, Inc.(RVMD) | 315,722 | 505,672 | +189,950 | $14.74M | $40.28M | 4.61% | +$25.53M |
| Agios Pharmaceuticals, Inc.(AGIO) | 0 | 1,303,373 | +1,303,373 | $0 | $35.48M | 4.06% | +$35.48M |
| uniQure N.V.(QURE) | 0 | 1,381,628 | +1,381,628 | $0 | $33.06M | 3.78% | +$33.06M |
| PTC Therapeutics, Inc.(PTCT) | 438,477 | 430,013 | -8,464 | $26.91M | $32.66M | 3.74% | +$5.75M |
| Syndax Pharmaceuticals, Inc.(SNDX) | 1,375,674 | 1,337,702 | -37,972 | $21.16M | $28.11M | 3.22% | +$6.94M |
| Dyne Therapeutics, Inc.(DYN) | 1,446,361 | 1,405,388 | -40,973 | $18.30M | $27.49M | 3.15% | +$9.19M |
| Tarsus Pharmaceuticals, Inc.(TARS) | 341,496 | 328,869 | -12,627 | $20.30M | $26.93M | 3.08% | +$6.63M |
| Stoke Therapeutics, Inc.(STOK) | 789,698 | 770,289 | -19,409 | $18.56M | $24.45M | 2.80% | +$5.89M |
| Alumis Inc | 0 | 2,401,992 | +2,401,992 | $0 | $23.44M | 2.68% | +$23.44M |
| UroGen Pharma Ltd.(URGN) | 135,000 | 941,378 | +806,378 | $2.69M | $22.05M | 2.52% | +$19.35M |
| Xenon Pharmaceuticals Inc.(XENE) | 503,398 | 485,620 | -17,778 | $20.21M | $21.77M | 2.49% | +$1.55M |
| Palvella Therapeutics, Inc.(PVLA) | 67,423 | 205,745 | +138,322 | $4.23M | $21.54M | 2.46% | +$17.31M |
| Natera, Inc.(NTRA) | 98,924 | 93,551 | -5,373 | $15.92M | $21.43M | 2.45% | +$5.51M |
| Corvus Pharmaceuticals, Inc.(CRVS) | 0 | 2,743,671 | +2,743,671 | $0 | $21.13M | 2.42% | +$21.13M |
| DBV Technologies S.A.ADS(DBVT) | 1,054,504 | 996,825 | -57,679 | $10.55M | $19.11M | 2.19% | +$8.56M |
| Relay Therapeutics, Inc.(RLAY) | 2,282,680 | 2,232,451 | -50,229 | $11.92M | $18.89M | 2.16% | +$6.97M |
| Monte Rosa Therapeutics, Inc.(GLUE) | 0 | 1,173,376 | +1,173,376 | $0 | $18.40M | 2.11% | +$18.40M |
| Bright Minds Biosciences Inc.(DRUG) | 0 | 230,147 | +230,147 | $0 | $17.96M | 2.06% | +$17.96M |
| Protagonist Therapeutics Inc | 0 | 199,471 | +199,471 | $0 | $17.42M | 1.99% | +$17.42M |
| enGene Holdings, Inc. COM | 530,299 | 1,840,898 | +1,310,599 | $3.62M | $16.62M | 1.90% | +$13.00M |
| Context Therapeutics Inc.(CNTX) | 14,705,882 | 10,679,391 | -4,026,491 | $14.25M | $15.70M | 1.80% | +$1.45M |
| Arcutis Biotherapeutics, Inc.(ARQT) | 0 | 531,200 | +531,200 | $0 | $15.43M | 1.77% | +$15.43M |
| Ventyx Biosciences Inc | 0 | 1,639,061 | +1,639,061 | $0 | $14.80M | 1.69% | +$14.80M |
| ORIC Pharmaceuticals, Inc.(ORIC) | 1,729,378 | 1,798,717 | +69,339 | $20.75M | $14.71M | 1.68% | -$6.04M |
| Belite Bio, IncADS(BLTE) | 0 | 87,760 | +87,760 | $0 | $14.04M | 1.61% | +$14.04M |
| RAPT Therapeutics Inc | 0 | 397,906 | +397,906 | $0 | $13.48M | 1.54% | +$13.48M |
| Climb Bio, Inc.(CLYM) | 0 | 2,671,480 | +2,671,480 | $0 | $10.69M | 1.22% | +$10.69M |
| ABIVAX Société AnonymeADS(ABVX) | 0 | 56,316 | +56,316 | $0 | $7.59M | 0.87% | +$7.59M |
| Rocket Pharmaceuticals, Inc.(RCKT) | 3,903,381 | 1,586,076 | -2,317,305 | $12.73M | $5.57M | 0.64% | -$7.16M |
| Maze Therapeutics, Inc.(MAZE) | 0 | 81,145 | +81,145 | $0 | $3.36M | 0.38% | +$3.36M |
| Evommune, Inc.(EVMN) | 0 | 113,022 | +113,022 | $0 | $1.93M | 0.22% | +$1.93M |
| Sarepta Therapeutics, Inc.(SRPT) | 700,000 | 70,000 | -630,000 | $13.49M | $1.51M | 0.17% | -$11.98M |
| Werewolf Therapeutics, Inc.(HOWL) | 2,408,810 | 1,393,557 | -1,015,253 | $4.75M | $883.5K | 0.10% | -$3.86M |
| Akebia Therapeutics, Inc.(AKBA) | 2,889,125 | 0 | -2,889,125 | $7.89M | $0 | — | -$7.89M |
| Alkermes plc(ALKS) | 549,262 | 0 | -549,262 | $16.48M | $0 | — | -$16.48M |
| ARS Pharmaceuticals, Inc.(SPRY) | 1,303,399 | 0 | -1,303,399 | $13.10M | $0 | — | -$13.10M |
| Assembly Biosciences Inc | 39,665 | 0 | -39,665 | $1.02M | $0 | — | -$1.02M |
| Avidity Biosciences Inc | 760,022 | 0 | -760,022 | $33.11M | $0 | — | -$33.11M |
| Cartesian Therapeutics, Inc.(RNAC) | 380,000 | 0 | -380,000 | $3.88M | $0 | — | -$3.88M |
| Compass Therapeutics, Inc.(CMPX) | 5,075,970 | 0 | -5,075,970 | $17.77M | $0 | — | -$17.77M |
| Design Therapeutics, Inc.(DSGN) | 555,187 | 0 | -555,187 | $4.18M | $0 | — | -$4.18M |
| Janux Therapeutics, Inc.(JANX) | 614,282 | 0 | -614,282 | $15.01M | $0 | — | -$15.01M |
| Rapport Therapeutics, Inc.(RAPP) | 71,807 | 0 | -71,807 | $2.13M | $0 | — | -$2.13M |
| Repare Therapeutics, Inc. | 819,924 | 0 | -819,924 | $1.44M | $0 | — | -$1.44M |
| Soleno Therapeutics Inc | 150,000 | 0 | -150,000 | $10.14M | $0 | — | -$10.14M |
| Solid Biosciences Inc | 1,634,569 | 0 | -1,634,569 | $10.09M | $0 | — | -$10.09M |
| Ultragenyx Pharmaceutical Inc.(RARE) | 395,700 | 0 | -395,700 | $11.90M | $0 | — | -$11.90M |
| Vera Therapeutics, Inc.CL A(VERA) | 563,075 | 0 | -563,075 | $16.36M | $0 | — | -$16.36M |
| Wave Life Sciences, Inc.(WVE) | 1,505,262 | 0 | -1,505,262 | $11.02M | $0 | — | -$11.02M |
| Zai Lab LimitedADR(ZLAB) | 745,060 | 0 | -745,060 | $25.25M | $0 | — | -$25.25M |