Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2024 ▲▼ | Q1 2025 ▲▼ | Change ▲▼ | Q4 2024 ▲▼ | Q1 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| SYNDAX PHARMACEUTICALS INC(SNDX) | 343,400 | 4,212,270 | +3,868,870 | 4,540 | 51,748 | 5.86% | +47,208 |
| NEUROCRINE BIOSCIENCES INC(NBIX) | 0 | 167,243 | +167,243 | 0 | 18,497 | 2.09% | +18,497 |
| GLAUKOS CORP(GKOS) | 0 | 158,957 | +158,957 | 0 | 15,645 | 1.77% | +15,645 |
| COMMUNITY HEALTH SYS INC NEW(CYH) | 2,827,000 | 8,458,020 | +5,631,020 | 8,453 | 22,837 | 2.58% | +14,384 |
| GLOBUS MED INC(GMED) | 0 | 192,893 | +192,893 | 0 | 14,120 | 1.60% | +14,120 |
| INVESCO QQQ TR | 0 | 24,003 | +24,003 | 0 | 11,255 | 1.27% | +11,255 |
| VAXCYTE INC(PCVX) | 127,588 | 557,070 | +429,482 | 10,444 | 21,035 | 2.38% | +10,591 |
| CENTENE CORP DEL(CNC) | 188,493 | 340,339 | +151,846 | 11,419 | 20,662 | 2.34% | +9,243 |
| IONIS PHARMACEUTICALS INC(IONS) | 214,952 | 517,021 | +302,069 | 7,515 | 15,599 | 1.77% | +8,084 |
| ALIGN TECHNOLOGY INC | 0 | 49,277 | +49,277 | 0 | 7,828 | 0.89% | +7,828 |
| MOLINA HEALTHCARE INC(MOH) | 0 | 23,735 | +23,735 | 0 | 7,818 | 0.88% | +7,818 |
| BRUKER CORP(BRKR) | 234,934 | 499,207 | +264,273 | 13,772 | 20,837 | 2.36% | +7,065 |
| TRAVERE THERAPEUTICS INC(TVTX) | 490,296 | 816,254 | +325,958 | 8,541 | 14,627 | 1.66% | +6,086 |
| VIRIDIAN THERAPEUTICS INC(VRDN) | 779,998 | 1,377,674 | +597,676 | 14,953 | 18,571 | 2.10% | +3,618 |
| NOVAVAX INC(NVAX) | 0 | 365,523 | +365,523 | 0 | 2,343 | 0.27% | +2,343 |
| UNITED THERAPEUTICS CORP DEL(UTHR) | 43,703 | 57,489 | +13,786 | 15,420 | 17,722 | 2.01% | +2,302 |
| 89BIO INC | 0 | 303,731 | +303,731 | 0 | 2,208 | 0.25% | +2,208 |
| ZENAS BIOPHARMA INC(ZBIO) | 172,103 | 445,588 | +273,485 | 1,410 | 3,520 | 0.40% | +2,111 |
| MARAVAI LIFESCIENCES HLDGS I(MRVI) | 0 | 942,454 | +942,454 | 0 | 2,083 | 0.24% | +2,083 |
| HUMANA INC(HUM) | 22,682 | 27,970 | +5,288 | 5,755 | 7,401 | 0.84% | +1,646 |
| BIOCRYST PHARMACEUTICALS INC(BCRX) | 1,980,312 | 2,172,436 | +192,124 | 14,892 | 16,293 | 1.84% | +1,401 |
| KARYOPHARM THERAPEUTICS INC(KPTI) | 0 | 257,154 | +257,154 | 0 | 962 | 0.11% | +962 |
| AMARIN CORP PLC | 1,516,592 | 3,399,204 | +1,882,612 | 736 | 1,523 | 0.17% | +788 |
| EHEALTH INC(EHTH) | 0 | 89,220 | +89,220 | 0 | 596 | 0.07% | +596 |
| INFLARX NV(IFRX) | 492,452 | 1,675,978 | +1,183,526 | 1,216 | 1,709 | 0.19% | +493 |
| ALECTOR INC | 200,095 | 617,418 | +417,323 | 378 | 759 | 0.09% | +381 |
| AUTOLUS THERAPEUTICS PLC(AUTL) | 98,895 | 343,947 | +245,052 | 232 | 533 | 0.06% | +301 |
| PROTAGONIST THERAPEUTICS INC | 678,787 | 547,116 | -131,671 | 26,201 | 26,459 | 2.99% | +257 |
| SUTRO BIOPHARMA INC(STRO) | 694,408 | 2,292,261 | +1,597,853 | 1,278 | 1,491 | 0.17% | +214 |
| AC IMMUNE SA(ACIU) | 0 | 100,752 | +100,752 | 0 | 188 | 0.02% | +188 |
| MERUS N V | 68,258 | 70,329 | +2,071 | 2,870 | 2,960 | 0.33% | +90 |
| HCA HEALTHCARE INC(HCA) | 175,808 | 152,502 | -23,306 | 52,769 | 52,697 | 5.96% | -72 |
| GOSSAMER BIO INC(GOSS) | 4,978,458 | 3,896,841 | -1,081,617 | 4,504 | 4,287 | 0.49% | -217 |
| ITEOS THERAPEUTICS INC | 220,196 | 220,196 | 0 | 1,691 | 1,315 | 0.15% | -377 |
| ABSCI CORPORATION | 199,464 | 0 | -199,464 | 523 | 0 | — | -523 |
| NEWAMSTERDAM PHARMA COMPANY ORDINARY SHARES | 275,362 | 280,951 | +5,589 | 7,077 | 5,751 | 0.65% | -1,326 |
| KARYOPHARM THERAPEUTICS INC(KPTI) | 2,088,757 | 0 | -2,088,757 | 1,413 | 0 | — | -1,413 |
| AVANTOR INC(AVTR) | 168,369 | 122,823 | -45,546 | 3,548 | 1,991 | 0.23% | -1,557 |
| XOMA ROYALTY CORPORATION | 95,417 | 45,017 | -50,400 | 2,508 | 897 | 0.10% | -1,610 |
| ICON PLC(ICLR) | 19,252 | 10,840 | -8,412 | 4,037 | 1,897 | 0.21% | -2,140 |
| PUMA BIOTECHNOLOGY INC(PBYI) | 996,102 | 275,788 | -720,314 | 3,038 | 816 | 0.09% | -2,222 |
| MANNKIND CORP(MNKD) | 911,025 | 697,710 | -213,315 | 5,858 | 3,509 | 0.40% | -2,348 |
| DENTSPLY SIRONA INC(XRAY) | 139,656 | 0 | -139,656 | 2,651 | 0 | — | -2,651 |
| ARCUTIS BIOTHERAPEUTICS INC(ARQT) | 191,158 | 0 | -191,158 | 2,663 | 0 | — | -2,663 |
| ZAI LAB LTD(ZLAB) | 102,930 | 0 | -102,930 | 2,696 | 0 | — | -2,696 |
| MEREO BIOPHARMA GROUP PLC(MREO) | 777,890 | 0 | -777,890 | 2,723 | 0 | — | -2,723 |
| 2SEVENTY BIO INC | 1,003,678 | 0 | -1,003,678 | 2,951 | 0 | — | -2,951 |
| TELEFLEX INCORPORATED(TFX) | 61,736 | 56,630 | -5,106 | 10,988 | 7,826 | 0.89% | -3,162 |
| SUPERNUS PHARMACEUTICALS INC(SUPN) | 105,581 | 0 | -105,581 | 3,818 | 0 | — | -3,818 |
| ELEVANCE HEALTH INC(ELV) | 29,178 | 15,698 | -13,480 | 10,764 | 6,828 | 0.77% | -3,936 |
| EVOLUS INC(EOLS) | 383,045 | 0 | -383,045 | 4,229 | 0 | — | -4,229 |
| LIQUIDIA CORPORATION(LQDA) | 571,305 | 150,480 | -420,825 | 6,719 | 2,220 | 0.25% | -4,499 |
| PATTERSON COS INC | 146,051 | 0 | -146,051 | 4,507 | 0 | — | -4,507 |
| DANAHER CORPORATION(DHR) | 22,209 | 0 | -22,209 | 5,098 | 0 | — | -5,098 |
| BIO-TECHNE CORP(TECH) | 299,310 | 280,117 | -19,193 | 21,559 | 16,423 | 1.86% | -5,136 |
| FORTREA HLDGS INC(FTRE) | 401,733 | 293,275 | -108,458 | 7,492 | 2,214 | 0.25% | -5,278 |
| REPLIGEN CORP(RGEN) | 54,066 | 18,452 | -35,614 | 7,782 | 2,348 | 0.27% | -5,434 |
| CELLDEX THERAPEUTICS INC NEW(CLDX) | 719,836 | 696,499 | -23,337 | 18,190 | 12,641 | 1.43% | -5,549 |
| HENRY SCHEIN INC(HSIC) | 80,303 | 0 | -80,303 | 5,557 | 0 | — | -5,557 |
| HEALTHEQUITY INC(HQY) | 386,697 | 351,976 | -34,721 | 37,104 | 31,104 | 3.52% | -5,999 |
| XENON PHARMACEUTICALS INC(XENE) | 155,540 | 0 | -155,540 | 6,097 | 0 | — | -6,097 |
| MEDPACE HLDGS INC(MEDP) | 19,049 | 0 | -19,049 | 6,329 | 0 | — | -6,329 |
| ZIMVIE INC | 2,070,780 | 2,079,380 | +8,600 | 28,887 | 22,457 | 2.54% | -6,430 |
| ASTRAZENECA PLC(AZN) | 102,661 | 0 | -102,661 | 6,726 | 0 | — | -6,726 |
| GUARDANT HEALTH INC(GH) | 276,036 | 0 | -276,036 | 8,433 | 0 | — | -8,433 |
| DEXCOM INC(DXCM) | 148,688 | 0 | -148,688 | 11,563 | 0 | — | -11,563 |
| REVVITY INC(RVTY) | 392,518 | 299,087 | -93,431 | 43,809 | 31,643 | 3.58% | -12,166 |
| NATERA INC(NTRA) | 876,766 | 893,721 | +16,955 | 138,792 | 126,381 | 14.30% | -12,411 |
| EDWARDS LIFESCIENCES CORP | 170,678 | 0 | -170,678 | 12,635 | 0 | — | -12,635 |
| VIATRIS INC(VTRS) | 1,272,102 | 0 | -1,272,102 | 15,838 | 0 | — | -15,838 |
| VERA THERAPEUTICS INC(VERA) | 1,600,015 | 1,898,804 | +298,789 | 67,665 | 45,609 | 5.16% | -22,055 |
| GSK PLC(GSK) | 3,661,768 | 2,623,246 | -1,038,522 | 123,841 | 101,625 | 11.50% | -22,216 |
| INSPIRE MED SYS INC(INSP) | 294,302 | 186,425 | -107,877 | 54,558 | 29,694 | 3.36% | -24,864 |
| TEVA PHARMACEUTICAL INDS LTD(TEVA) | 2,242,125 | 1,410,765 | -831,360 | 49,416 | 21,683 | 2.45% | -27,733 |