Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| REVOLUTION MEDICINES INC(RVMD) | 1,283,900 | 1,652,808 | +368,908 | 102,263 | 160,736 | 11.37% | +58,473 |
| XENON PHARMACEUTICALS INC(XENE) | 549,665 | 1,393,027 | +843,362 | 24,636 | 81,005 | 5.73% | +56,369 |
| SPYRE THERAPEUTICS INC(SYRE) | 0 | 878,127 | +878,127 | 0 | 44,293 | 3.13% | +44,293 |
| VAXCYTE INC(PCVX) | 1,704,815 | 2,060,719 | +355,904 | 78,660 | 119,748 | 8.47% | +41,088 |
| LB PHARMACEUTICALS INC(LBRX) | 0 | 1,438,070 | +1,438,070 | 0 | 34,629 | 2.45% | +34,629 |
| SAB BIOTHERAPEUTICS INC(SABS) | 0 | 7,967,207 | +7,967,207 | 0 | 30,514 | 2.16% | +30,514 |
| OPUS GENETICS INC(IRD) | 0 | 6,075,028 | +6,075,028 | 0 | 27,641 | 1.96% | +27,641 |
| LIQUIDIA CORPORATION(LQDA) | 8,118,892 | 8,118,892 | 0 | 280,021 | 306,407 | 21.67% | +26,386 |
| MBX BIOSCIENCES INC(MBX) | 0 | 848,590 | +848,590 | 0 | 25,330 | 1.79% | +25,330 |
| VOR BIOPHARMA INC(VOR) | 925,067 | 1,925,066 | +999,999 | 9,963 | 34,343 | 2.43% | +24,380 |
| TYRA BIOSCIENCES INC(TYRA) | 944,257 | 1,276,968 | +332,711 | 24,825 | 48,908 | 3.46% | +24,083 |
| INVENTIVA SA(IVA) | 2,000,000 | 4,974,906 | +2,974,906 | 9,300 | 27,611 | 1.95% | +18,311 |
| TANGO THERAPEUTICS INC(TNGX) | 3,729,895 | 2,408,798 | -1,321,097 | 33,047 | 50,392 | 3.56% | +17,345 |
| AVALO THERAPEUTICS INC(AVTX) | 881,533 | 1,635,023 | +753,490 | 16,009 | 24,411 | 1.73% | +8,402 |
| ANIKA THERAPEUTICS INC | 1,435,130 | 1,435,130 | 0 | 13,792 | 20,809 | 1.47% | +7,018 |
| SENSEI BIOTHERAPEUTICS INC(FTH) | 0 | 126,002 | +126,002 | 0 | 3,972 | 0.28% | +3,972 |
| AURA BIOSCIENCES INC(AURA) | 0 | 229,864 | +229,864 | 0 | 1,538 | 0.11% | +1,538 |
| XILIO THERAPEUTICS INC(XLO) | 0 | 112,128 | +112,128 | 0 | 943 | 0.07% | +943 |
| ELEDON PHARMACEUTICALS INC(ELDN) | 555,978 | 0 | -555,978 | 840 | 0 | — | -840 |
| EXELIXIS INC(EXEL) | 1,553,262 | 1,553,262 | 0 | 68,079 | 66,619 | 4.71% | -1,460 |
| SPRUCE BIOSCIENCES INC | 20,514 | 0 | -20,514 | 1,787 | 0 | — | -1,787 |
| VERRICA PHARMACEUTICALS INC(VRCA) | 923,910 | 923,910 | 0 | 7,678 | 4,887 | 0.35% | -2,790 |
| MAZE THERAPEUTICS INC(MAZE) | 550,191 | 614,962 | +64,771 | 22,794 | 18,357 | 1.30% | -4,438 |
| ADMA BIOLOGICS INC | 3,012,508 | 4,756,511 | +1,744,003 | 54,948 | 42,856 | 3.03% | -12,092 |
| RAPT THERAPEUTICS INC | 644,400 | 0 | -644,400 | 21,826 | 0 | — | -21,826 |
| MINERALYS THERAPEUTICS INC(MLYS) | 2,772,654 | 2,772,654 | 0 | 100,620 | 75,111 | 5.31% | -25,508 |
| INHIBRX BIOSCIENCES INC(INBX) | 323,565 | 0 | -323,565 | 25,562 | 0 | — | -25,562 |
| ABIVAX SA(ABVX) | 1,451,924 | 1,461,924 | +10,000 | 195,799 | 162,785 | 11.51% | -33,014 |