Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q3 2024 ▲▼ | Q4 2024 ▲▼ | Change ▲▼ | Q3 2024 ▲▼ | Q4 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| SCHOLAR ROCK HLDG CORP(SRRK) | 6,788,609 | 5,612,896 | -1,175,713 | 54,377 | 242,589 | 33.30% | +188,213 |
| SEPTERNA INC(SEPN) | 0 | 2,768,520 | +2,768,520 | 0 | 63,399 | 8.70% | +63,399 |
| UPSTREAM BIO INC(UPB) | 0 | 2,217,146 | +2,217,146 | 0 | 36,450 | 5.00% | +36,450 |
| PALVELLA THERAPEUTICS INC NE(PVLA) | 0 | 679,486 | +679,486 | 0 | 8,154 | 1.12% | +8,154 |
| ONKURE THERAPEUTICS INC(OKUR) | 0 | 824,155 | +824,155 | 0 | 7,088 | 0.97% | +7,088 |
| ACLARIS THERAPEUTICS INC(ACRS) | 696,171 | 2,385,060 | +1,688,889 | 801 | 5,915 | 0.81% | +5,114 |
| ZYMEWORKS INC(ZYME) | 1,000,000 | 1,000,000 | 0 | 12,550 | 14,640 | 2.01% | +2,090 |
| JASPER THERAPEUTICS INC(JSPR) | 584,642 | 584,642 | 0 | 10,997 | 12,500 | 1.72% | +1,503 |
| MINERALYS THERAPEUTICS INC(MLYS) | 5,074,916 | 5,074,916 | 0 | 61,457 | 62,472 | 8.57% | +1,015 |
| LEAP THERAPEUTICS INC(CYPH) | 2,442,352 | 2,442,352 | 0 | 6,277 | 7,022 | 0.96% | +745 |
| RHYTHM PHARMACEUTICALS INC(RYTM) | 172,647 | 172,647 | 0 | 9,045 | 9,665 | 1.33% | +620 |
| CURIS INC(CRIS) | 0 | 198,216 | +198,216 | 0 | 607 | 0.08% | +607 |
| ALLAKOS INC | 172,089 | 172,089 | 0 | 112 | 208 | 0.03% | +96 |
| VTV THERAPEUTICS INC(VTVT) | 206,784 | 206,784 | 0 | 2,805 | 2,855 | 0.39% | +50 |
| NUVATION BIO INC(NUVB) | 133,333 | 133,333 | 0 | 13 | 31 | 0.00% | +18 |
| SURROZEN INC(SRZN) | 99,999 | 99,999 | 0 | 1 | 2 | 0.00% | +1 |
| KRONOS BIO INC | 78,131 | 78,131 | 0 | 78 | 74 | 0.01% | -4 |
| ALLOVIR INC | 82,336 | 82,336 | 0 | 67 | 35 | 0.00% | -32 |
| BOLT BIOTHERAPEUTICS INC | 1,049,153 | 1,049,153 | 0 | 680 | 561 | 0.08% | -118 |
| VIRACTA THERAPEUTICS INC | 689,709 | 0 | -689,709 | 160 | 0 | — | -160 |
| DAY ONE BIOPHARMACEUTICALS I COM | 147,319 | 147,319 | 0 | 2,052 | 1,867 | 0.26% | -186 |
| LENZ THERAPEUTICS INC(LENZ) | 1,208,473 | 986,981 | -221,492 | 28,689 | 28,494 | 3.91% | -195 |
| LYRA THERAPEUTICS INC | 2,780,261 | 1,965,689 | -814,572 | 715 | 406 | 0.06% | -309 |
| JANUX THERAPEUTICS INC(JANX) | 22,526 | 11,263 | -11,263 | 1,023 | 603 | 0.08% | -420 |
| GOSSAMER BIO INC(GOSS) | 6,130,268 | 6,130,268 | 0 | 6,047 | 5,545 | 0.76% | -501 |
| TERNS PHARMACEUTICALS INC | 202,348 | 202,348 | 0 | 1,688 | 1,121 | 0.15% | -567 |
| HILLEVAX INC | 799,274 | 399,637 | -399,637 | 1,407 | 827 | 0.11% | -579 |
| IMMATICS N.V(IMTX) | 198,000 | 198,000 | 0 | 2,259 | 1,408 | 0.19% | -851 |
| BICARA THERAPEUTICS INC | 35,000 | 0 | -35,000 | 891 | 0 | — | -891 |
| PRIME MEDICINE INC(PRME) | 540,304 | 405,228 | -135,076 | 2,091 | 1,183 | 0.16% | -908 |
| VERONA PHARMA PLC | 195,225 | 97,625 | -97,600 | 5,617 | 4,534 | 0.62% | -1,083 |
| ARTIVA BIOTHERAPEUTICS INC(ARTV) | 291,666 | 291,666 | 0 | 4,506 | 2,940 | 0.40% | -1,566 |
| AVADEL PHARMACEUTICALS PLC | 967,527 | 967,527 | 0 | 12,689 | 10,169 | 1.40% | -2,520 |
| CONTINEUM THERAPEUTICS INC(CTNM) | 588,816 | 588,816 | 0 | 11,270 | 8,626 | 1.18% | -2,644 |
| TANGO THERAPEUTICS INC(TNGX) | 630,000 | 630,000 | 0 | 4,851 | 1,947 | 0.27% | -2,904 |
| SUTRO BIOPHARMA INC(STRO) | 2,196,814 | 2,196,814 | 0 | 7,601 | 4,042 | 0.55% | -3,559 |
| ABIVAX SA(ABVX) | 850,000 | 850,000 | 0 | 9,792 | 6,222 | 0.85% | -3,570 |
| IO BIOTECH INC(IOBTQ) | 3,640,015 | 0 | -3,640,015 | 3,822 | 0 | — | -3,822 |
| SYROS PHARMACEUTICALS INC | 1,786,427 | 0 | -1,786,427 | 3,841 | 0 | — | -3,841 |
| INOZYME PHARMA INC | 1,562,500 | 1,562,500 | 0 | 8,172 | 4,328 | 0.59% | -3,844 |
| ACELYRIN INC | 2,523,022 | 2,523,022 | 0 | 12,438 | 7,922 | 1.09% | -4,516 |
| NKARTA INC(NKTX) | 3,768,035 | 3,768,035 | 0 | 17,032 | 9,382 | 1.29% | -7,649 |
| CLIMB BIO INC(CLYM) | 2,609,114 | 2,609,114 | 0 | 13,280 | 4,696 | 0.64% | -8,584 |
| ALUMIS INC | 3,266,498 | 3,266,498 | 0 | 34,886 | 25,675 | 3.52% | -9,212 |
| ARCELLX INC COMMON STOCK | 353,641 | 253,641 | -100,000 | 29,533 | 19,452 | 2.67% | -10,081 |
| NEUROGENE INC(NGNE) | 1,267,790 | 1,717,127 | +449,337 | 53,196 | 39,254 | 5.39% | -13,943 |
| CARGO THERAPEUTICS INC | 4,415,689 | 4,415,689 | 0 | 81,469 | 63,674 | 8.74% | -17,795 |