Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Apogee Therapeutics Inc | 1,234,926 | 1,284,926 | +50,000 | $93.21M | $108.15M | 6.34% | +$14.94M |
| Xenon Pharmaceuticals Inc.(XENE) | 1,250,000 | 1,675,000 | +425,000 | $56.02M | $97.40M | 5.71% | +$41.38M |
| Erasca, Inc.(ERAS) | 3,900,000 | 5,350,000 | +1,450,000 | $14.51M | $86.56M | 5.08% | +$72.06M |
| Insmed Incorporated(INSM) | 450,000 | 480,000 | +30,000 | $78.32M | $78.49M | 4.60% | +$171.6K |
| Roivant Sciences Ltd.SHS(ROIV) | 1,700,000 | 2,800,000 | +1,100,000 | $36.89M | $77.56M | 4.55% | +$40.67M |
| Spyre Therapeutics, Inc.(SYRE) | 1,432,591 | 1,279,134 | -153,457 | $46.93M | $64.52M | 3.78% | +$17.59M |
| Centessa Pharmaceuticals PlcADS | 600,552 | 1,400,000 | +799,448 | $15.02M | $55.61M | 3.26% | +$40.59M |
| Praxis Precision Medicines, Inc.(PRAX) | 185,000 | 170,000 | -15,000 | $54.53M | $54.77M | 3.21% | +$245.4K |
| Anaptysbio Inc | 444,692 | 940,000 | +495,308 | $21.56M | $52.13M | 3.06% | +$30.57M |
| Alkermes plcSHS(ALKS) | 1,000,000 | 1,350,000 | +350,000 | $27.98M | $47.74M | 2.80% | +$19.76M |
| Cytokinetics, Incorporated(CYTK) | 800,000 | 700,483 | -99,517 | $50.83M | $46.17M | 2.71% | -$4.66M |
| ABIVAX Société AnonymeADS(ABVX) | 505,000 | 405,000 | -100,000 | $68.10M | $45.10M | 2.64% | -$23.01M |
| Teva Pharmaceutical Industries LimitedADS(TEVA) | 1,400,000 | 1,400,000 | 0 | $43.69M | $42.17M | 2.47% | -$1.53M |
| Arcellx Inc COMMON STOCK | 523,725 | 362,764 | -160,961 | $34.15M | $41.65M | 2.44% | +$7.51M |
| Nuvalent Inc | 322,633 | 300,000 | -22,633 | $32.45M | $30.73M | 1.80% | -$1.72M |
| Terns Pharmaceuticals Inc | 550,000 | 562,631 | +12,631 | $22.22M | $29.66M | 1.74% | +$7.44M |
| Dianthus Therapeutics, Inc.(DNTH) | 115,000 | 350,000 | +235,000 | $4.74M | $29.37M | 1.72% | +$24.63M |
| Lexeo Therapeutics, Inc.(LXEO) | 3,200,000 | 5,050,211 | +1,850,211 | $31.78M | $28.99M | 1.70% | -$2.79M |
| Cogent Biosciences, Inc.(COGT) | 350,000 | 750,000 | +400,000 | $12.43M | $28.87M | 1.69% | +$16.44M |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 31,131 | 55,000 | +23,869 | $18.13M | $28.79M | 1.69% | +$10.66M |
| Sutro Biopharma, Inc.(STRO) | 748,382 | 1,069,519 | +321,137 | $8.66M | $26.64M | 1.56% | +$17.98M |
| Forte Biosciences Inc | 989,490 | 1,011,890 | +22,400 | $26.98M | $26.21M | 1.54% | -$775.4K |
| Oruka Therapeutics, Inc.(ORKA) | 802,342 | 499,673 | -302,669 | $24.32M | $24.51M | 1.44% | +$190.0K |
| Trevi Therapeutics, Inc.(TRVI) | 2,150,172 | 2,000,172 | -150,000 | $26.92M | $23.86M | 1.40% | -$3.06M |
| Ovid Therapeutics Inc.(OVID) | 7,150,000 | 10,636,318 | +3,486,318 | $11.65M | $23.61M | 1.38% | +$11.96M |
| Enliven Therapeutics Inc | 0 | 586,904 | +586,904 | $0 | $23.01M | 1.35% | +$23.01M |
| Ascendis Pharma A/SADR(ASND) | 30,000 | 95,000 | +65,000 | $6.40M | $21.73M | 1.27% | +$15.33M |
| Mineralys Therapeutics, Inc.(MLYS) | 730,000 | 750,000 | +20,000 | $26.49M | $20.32M | 1.19% | -$6.17M |
| Avalo Therapeutics, Inc.(AVTX) | 1,051,054 | 1,340,840 | +289,786 | $19.09M | $20.02M | 1.17% | +$931.6K |
| Protagonist Therapeutics Inc | 172,125 | 172,125 | 0 | $15.03M | $18.14M | 1.06% | +$3.11M |
| Celldex Therapeutics, Inc.(CLDX) | 350,000 | 500,000 | +150,000 | $9.51M | $15.86M | 0.93% | +$6.35M |
| Zura Bio LimitedCL A(ZURA) | 1,813,671 | 2,564,303 | +750,632 | $9.50M | $15.26M | 0.89% | +$5.75M |
| Nurix Therapeutics, Inc.(NRIX) | 967,620 | 967,620 | 0 | $18.36M | $15.00M | 0.88% | -$3.36M |
| Savara Inc.(SVRA) | 2,797,153 | 2,512,153 | -285,000 | $16.87M | $13.72M | 0.80% | -$3.15M |
| Omeros CorporationNOTE 9 500 6 1(OMER) | 0 | 0 | 0 | $19.38M | $13.22M | 0.78% | -$6.16M |
| Perspective Therapeutics, Inc.(CATX) | 300,000 | 3,164,582 | +2,864,582 | $825.0K | $13.20M | 0.77% | +$12.37M |
| Helix Acquisition Corp. IIICL A(HLXC) | 0 | 1,250,000 | +1,250,000 | $0 | $12.70M | 0.74% | +$12.70M |
| Arrowhead Pharmaceuticals, Inc.(ARWR) | 70,000 | 200,000 | +130,000 | $4.65M | $12.54M | 0.74% | +$7.89M |
| Damora Therapeutics, Inc.(DMRA) | 0 | 450,000 | +450,000 | $0 | $11.65M | 0.68% | +$11.65M |
| Eupraxia Pharmaceuticals Inc.(EPRX) | 300,000 | 1,589,005 | +1,289,005 | $2.27M | $11.50M | 0.67% | +$9.24M |
| Alto Neuroscience, Inc.(ANRO) | 0 | 500,000 | +500,000 | $0 | $11.24M | 0.66% | +$11.24M |
| BridgeBio Pharma, Inc.(BBIO) | 320,000 | 150,000 | -170,000 | $24.48M | $11.14M | 0.65% | -$13.34M |
| Cullinan Therapeutics, Inc.(CGEM) | 1,932,106 | 781,260 | -1,150,846 | $20.00M | $11.10M | 0.65% | -$8.90M |
| Belite Bio, IncADS(BLTE) | 20,000 | 65,000 | +45,000 | $3.20M | $10.36M | 0.61% | +$7.16M |
| Wave Life Sciences, Inc.SHS(WVE) | 2,700,000 | 1,401,727 | -1,298,273 | $45.90M | $10.16M | 0.60% | -$35.74M |
| Vera Therapeutics, Inc.CL A(VERA) | 250,000 | 250,000 | 0 | $12.66M | $10.06M | 0.59% | -$2.60M |
| Tyra Biosciences, Inc.(TYRA) | 0 | 257,512 | +257,512 | $0 | $9.86M | 0.58% | +$9.86M |
| Revolution Medicines, Inc.(RVMD) | 100,000 | 100,000 | 0 | $7.96M | $9.72M | 0.57% | +$1.76M |
| Jade Biosciences Inc | 714,956 | 639,956 | -75,000 | $11.03M | $8.99M | 0.53% | -$2.04M |
| Travere Therapeutics, Inc.(TVTX) | 300,000 | 300,000 | 0 | $11.46M | $8.91M | 0.52% | -$2.55M |
| Newamsterdam Pharma Company ORDINARY SHARES | 275,000 | 275,000 | 0 | $9.65M | $8.80M | 0.52% | -$844.3K |
| Cogent Biosciences, Inc.NOTE 1 625 11 1(COGT) | 0 | 0 | 0 | $1.18M | $8.59M | 0.50% | +$7.41M |
| Korro Bio, Inc.(KRRO) | 0 | 706,904 | +706,904 | $0 | $8.00M | 0.47% | +$8.00M |
| Celcuity Inc.NOTE 2 750 8 0(CELC) | 0 | 0 | 0 | $6.52M | $7.31M | 0.43% | +$798.3K |
| CRISPR Therapeutics AGNAMEN AKT(CRSP) | 0 | 150,000 | +150,000 | $0 | $7.14M | 0.42% | +$7.14M |
| SpyGlass Pharma, Inc.(SGP) | 0 | 250,000 | +250,000 | $0 | $6.48M | 0.38% | +$6.48M |
| COMPASS Pathways plcADS(CMPS) | 200,000 | 1,108,483 | +908,483 | $1.38M | $6.13M | 0.36% | +$4.75M |
| iBio, Inc.(IBIO) | 2,057,200 | 3,107,200 | +1,050,000 | $3.97M | $5.90M | 0.35% | +$1.93M |
| Establishment Labs Holdings Inc.(ESTA) | 200,000 | 100,000 | -100,000 | $14.58M | $5.68M | 0.33% | -$8.90M |
| Anteris Technologies Global Corp.(AVR) | 486,684 | 912,397 | +425,713 | $2.43M | $5.06M | 0.30% | +$2.64M |
| Newamsterdam Pharma CompanyW EXP 99 99 999 *W EXP 99/99/999 | 245,000 | 245,000 | 0 | $5.63M | $4.91M | 0.29% | -$725.2K |
| Viridian Therapeutics, Inc.(VRDN) | 250,000 | 250,000 | 0 | $7.78M | $4.89M | 0.29% | -$2.89M |
| Climb Bio, Inc.(CLYM) | 1,300,000 | 700,000 | -600,000 | $5.20M | $4.79M | 0.28% | -$405.0K |
| Rezolute, Inc.(RZLT) | 2,351,144 | 1,547,641 | -803,503 | $5.55M | $4.72M | 0.28% | -$828.4K |
| Sagimet Biosciences Inc.COM SER A(SGMT) | 1,148,245 | 868,020 | -280,225 | $6.80M | $4.54M | 0.27% | -$2.26M |
| MBX Biosciences, Inc.(MBX) | 250,000 | 150,000 | -100,000 | $7.88M | $4.48M | 0.26% | -$3.41M |
| Taysha Gene Therapies, Inc.(TSHA) | 3,300,000 | 1,000,000 | -2,300,000 | $18.15M | $4.47M | 0.26% | -$13.68M |
| Veradermics, Incorporated(MANE) | 0 | 70,000 | +70,000 | $0 | $4.42M | 0.26% | +$4.42M |
| Generate Biomedicines, Inc.(GENB) | 0 | 350,000 | +350,000 | $0 | $4.38M | 0.26% | +$4.38M |
| Engene Holdings Inc COM | 643,370 | 610,370 | -33,000 | $5.81M | $4.16M | 0.24% | -$1.65M |
| ArriVent BioPharma, Inc.(AVBP) | 150,000 | 175,000 | +25,000 | $3.02M | $4.04M | 0.24% | +$1.02M |
| Relay Therapeutics, Inc.(RLAY) | 0 | 400,000 | +400,000 | $0 | $3.98M | 0.23% | +$3.98M |
| Proqr Thrapeutics N VSHS EURO SHS EURO | 2,454,278 | 2,454,278 | 0 | $4.96M | $3.98M | 0.23% | -$981.7K |
| Verrica Pharmaceuticals Inc.(VRCA) | 707,338 | 707,338 | 0 | $5.88M | $3.74M | 0.22% | -$2.14M |
| Precision BioSciences, Inc.(DTIL) | 0 | 597,946 | +597,946 | $0 | $3.29M | 0.19% | +$3.29M |
| Karyopharm Therapeutics Inc.(KPTI) | 889,575 | 500,000 | -389,575 | $6.55M | $2.79M | 0.16% | -$3.76M |
| Sol-Gel Technologies LtdSHS NEW SHS NEW | 0 | 35,000 | +35,000 | $0 | $2.77M | 0.16% | +$2.77M |
| Crinetics Pharmaceuticals In | 75,000 | 75,000 | 0 | $3.49M | $2.72M | 0.16% | -$767.3K |
| Oaktree Acquisition Corp IiiUNIT 10 04 2029 UNIT 10/04/2029 | 250,000 | 250,000 | 0 | $2.65M | $2.66M | 0.16% | +$10.0K |
| Nextcure Inc | 247,294 | 241,826 | -5,468 | $3.51M | $2.58M | 0.15% | -$926.4K |
| Immunovant, Inc.(IMVT) | 200,000 | 100,000 | -100,000 | $5.08M | $2.48M | 0.15% | -$2.60M |
| Equillium, Inc.(EQ) | 0 | 1,226,310 | +1,226,310 | $0 | $2.45M | 0.14% | +$2.45M |
| SAB Biotherapeutics, Inc.(SABS) | 0 | 575,000 | +575,000 | $0 | $2.20M | 0.13% | +$2.20M |
| Corcept Therapeutics Incorporated(CORT) | 0 | 50,000 | +50,000 | $0 | $2.02M | 0.12% | +$2.02M |
| Orchestra BioMed Holdings, Inc.(OBIO) | 572,804 | 402,550 | -170,254 | $2.38M | $1.71M | 0.10% | -$666.3K |
| Kezar Life Sciences Inc COM NEW | 229,076 | 229,076 | 0 | $1.44M | $1.70M | 0.10% | +$258.9K |
| MacroGenics, Inc.(MGNX) | 484,308 | 500,000 | +15,692 | $779.7K | $1.45M | 0.08% | +$665.3K |
| Adlai Nortye Group Ltd.ADS(ANL) | 0 | 164,748 | +164,748 | $0 | $1.14M | 0.07% | +$1.14M |
| Alector Inc | 0 | 500,000 | +500,000 | $0 | $1.07M | 0.06% | +$1.07M |
| OnKure Therapeutics, Inc.CL A(OKUR) | 0 | 240,963 | +240,963 | $0 | $997.6K | 0.06% | +$997.6K |
| LENZ Therapeutics, Inc.(LENZ) | 0 | 100,000 | +100,000 | $0 | $915.0K | 0.05% | +$915.0K |
| X4 Pharmaceuticals, Inc.(XFOR) | 145,000 | 145,000 | 0 | $580.0K | $598.9K | 0.04% | +$18.9K |
| Q32 Bio Inc.(QTTB) | 27,777 | 27,777 | 0 | $92.2K | $178.3K | 0.01% | +$86.1K |
| Adagio Medical Holdings, Inc.(ADGM) | 80,000 | 80,000 | 0 | $83.2K | $92.0K | 0.01% | +$8.8K |
| Rocket Pharmaceuticals, Inc.W EXP 09 02 202(RCKT) | 75,000 | 75,000 | 0 | $1.8K | $1.2K | 0.00% | -$645 |
| Amgen Inc.(AMGN) | 10,000 | 0 | -10,000 | $3.27M | $0 | — | -$3.27M |
| Arcus Biosciences, Inc.(RCUS) | 300,000 | 0 | -300,000 | $7.15M | $0 | — | -$7.15M |
| Avadel Pharmaceuticals Plc | 250,000 | 0 | -250,000 | $5.39M | $0 | — | -$5.39M |
| Geron Corporation(GERN) | 1,500,000 | 0 | -1,500,000 | $1.98M | $0 | — | -$1.98M |
| Mersana Therapeutics Inc | 100,000 | 0 | -100,000 | $2.89M | $0 | — | -$2.89M |