Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q2 2025 ▲▼ | Q3 2025 ▲▼ | Change ▲▼ | Q2 2025 ▲▼ | Q3 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Verona Pharma PlcADS | 610,000 | 625,000 | +15,000 | $57.69M | $66.69M | 6.21% | +$9.00M |
| Insmed Incorporated(INSM) | 475,000 | 450,000 | -25,000 | $47.80M | $64.80M | 6.03% | +$17.00M |
| State Street SPDR S&P 500 ETF TrustTR UNIT(SPY) | 0 | 84,490 | +84,490 | $0 | $56.29M | 5.24% | +$56.29M |
| Xenon Pharmaceuticals Inc.(XENE) | 1,100,000 | 1,400,000 | +300,000 | $34.43M | $56.21M | 5.23% | +$21.78M |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 80,000 | 115,000 | +35,000 | $24.21M | $52.75M | 4.91% | +$28.53M |
| Apogee Therapeutics Inc | 691,899 | 1,173,426 | +481,527 | $30.05M | $46.62M | 4.34% | +$16.57M |
| Arcellx Inc COMMON STOCK | 495,000 | 500,000 | +5,000 | $32.60M | $41.05M | 3.82% | +$8.45M |
| Alkermes plcSHS(ALKS) | 1,000,000 | 1,250,000 | +250,000 | $28.61M | $37.50M | 3.49% | +$8.89M |
| Nuvalent Inc | 415,000 | 384,417 | -30,583 | $31.66M | $33.24M | 3.09% | +$1.58M |
| ABIVAX Société AnonymeADS(ABVX) | 100,000 | 360,000 | +260,000 | $765.0K | $30.56M | 2.84% | +$29.80M |
| Mineralys Therapeutics, Inc.(MLYS) | 900,000 | 750,000 | -150,000 | $12.18M | $28.44M | 2.65% | +$16.26M |
| Teva Pharmaceutical Industries LimitedADS(TEVA) | 1,400,000 | 1,400,000 | 0 | $23.46M | $28.28M | 2.63% | +$4.82M |
| Merus N V | 70,000 | 285,769 | +215,769 | $3.68M | $26.91M | 2.50% | +$23.22M |
| Centessa Pharmaceuticals PlcADS | 900,162 | 1,107,162 | +207,000 | $11.83M | $26.85M | 2.50% | +$15.02M |
| Lexeo Therapeutics, Inc.(LXEO) | 3,589,355 | 3,870,527 | +281,172 | $14.43M | $25.70M | 2.39% | +$11.27M |
| Trevi Therapeutics, Inc.(TRVI) | 2,534,058 | 2,800,000 | +265,942 | $13.86M | $25.62M | 2.38% | +$11.76M |
| Spyre Therapeutics, Inc.(SYRE) | 606,678 | 1,419,299 | +812,621 | $9.08M | $23.79M | 2.21% | +$14.71M |
| Rezolute, Inc.(RZLT) | 2,200,000 | 2,100,000 | -100,000 | $9.81M | $19.74M | 1.84% | +$9.93M |
| Cytokinetics, Incorporated(CYTK) | 0 | 350,000 | +350,000 | $0 | $19.24M | 1.79% | +$19.24M |
| Oruka Therapeutics, Inc.(ORKA) | 603,479 | 959,180 | +355,701 | $6.76M | $18.45M | 1.72% | +$11.68M |
| uniQure N.V.SHS(QURE) | 135,000 | 300,000 | +165,000 | $1.88M | $17.51M | 1.63% | +$15.63M |
| Wave Life Sciences, Inc.SHS(WVE) | 2,000,308 | 2,100,000 | +99,692 | $13.00M | $15.37M | 1.43% | +$2.37M |
| Protagonist Therapeutics Inc | 440,000 | 220,600 | -219,400 | $24.32M | $14.65M | 1.36% | -$9.66M |
| Soleno Therapeutics Inc | 0 | 200,000 | +200,000 | $0 | $13.52M | 1.26% | +$13.52M |
| Avalo Therapeutics, Inc.(AVTX) | 607,872 | 1,006,217 | +398,345 | $3.03M | $12.79M | 1.19% | +$9.76M |
| Establishment Labs Holdings Inc.(ESTA) | 334,863 | 310,000 | -24,863 | $14.30M | $12.71M | 1.18% | -$1.60M |
| Karyopharm Therapeutics IncNOTE 3 000 10 1 | 0 | 0 | 0 | $11.62M | $12.46M | 1.16% | +$835.7K |
| Ventyx Biosciences Inc | 4,536,182 | 3,924,415 | -611,767 | $9.71M | $12.20M | 1.14% | +$2.50M |
| Roivant Sciences Ltd.SHS(ROIV) | 400,000 | 800,000 | +400,000 | $4.51M | $12.10M | 1.13% | +$7.60M |
| Travere Therapeutics, Inc.(TVTX) | 970,000 | 500,000 | -470,000 | $14.36M | $11.95M | 1.11% | -$2.41M |
| Dianthus Therapeutics, Inc.(DNTH) | 0 | 262,100 | +262,100 | $0 | $10.31M | 0.96% | +$10.31M |
| Taysha Gene Therapies, Inc.(TSHA) | 200,000 | 3,000,000 | +2,800,000 | $462.0K | $9.81M | 0.91% | +$9.35M |
| Erasca, Inc.(ERAS) | 4,085,787 | 4,285,787 | +200,000 | $5.19M | $9.34M | 0.87% | +$4.15M |
| Nurix Therapeutics, Inc.(NRIX) | 967,620 | 967,620 | 0 | $11.02M | $8.94M | 0.83% | -$2.08M |
| Vera Therapeutics, Inc.CL A(VERA) | 545,000 | 303,330 | -241,670 | $12.84M | $8.81M | 0.82% | -$4.03M |
| Enliven Therapeutics Inc | 400,000 | 400,000 | 0 | $8.02M | $8.19M | 0.76% | +$164.0K |
| Travere Therapeutics, Inc.NOTE 2 250 3 0(TVTX) | 0 | 0 | 0 | $6.69M | $7.93M | 0.74% | +$1.24M |
| Newamsterdam Pharma Company ORDINARY SHARES | 275,000 | 275,000 | 0 | $4.98M | $7.82M | 0.73% | +$2.84M |
| Celldex Therapeutics, Inc.(CLDX) | 0 | 300,000 | +300,000 | $0 | $7.76M | 0.72% | +$7.76M |
| Proqr Thrapeutics N VSHS EURO SHS EURO | 3,499,512 | 3,600,000 | +100,488 | $7.14M | $7.67M | 0.71% | +$529.0K |
| Tarsus Pharmaceuticals, Inc.(TARS) | 0 | 125,000 | +125,000 | $0 | $7.43M | 0.69% | +$7.43M |
| Akebia Therapeutics, Inc.(AKBA) | 1,950,000 | 2,450,000 | +500,000 | $7.10M | $6.69M | 0.62% | -$409.5K |
| Monopar Therapeutics Inc.(MNPR) | 67,500 | 79,483 | +11,983 | $2.42M | $6.49M | 0.60% | +$4.08M |
| Zura Bio LimitedCL A(ZURA) | 223,335 | 1,274,351 | +1,051,016 | $234.5K | $5.52M | 0.51% | +$5.28M |
| Viridian Therapeutics, Inc.(VRDN) | 390,000 | 250,000 | -140,000 | $5.45M | $5.39M | 0.50% | -$57.2K |
| Savara Inc.(SVRA) | 500,000 | 1,500,000 | +1,000,000 | $1.14M | $5.36M | 0.50% | +$4.21M |
| Immunovant, Inc.(IMVT) | 0 | 300,000 | +300,000 | $0 | $4.84M | 0.45% | +$4.84M |
| Omeros CorporationNOTE 9 500 6 1(OMER) | 0 | 0 | 0 | $7.07M | $4.71M | 0.44% | -$2.36M |
| Revolution Medicines, Inc.(RVMD) | 0 | 100,000 | +100,000 | $0 | $4.67M | 0.43% | +$4.67M |
| Vaxcyte, Inc.(PCVX) | 125,000 | 125,000 | 0 | $4.06M | $4.50M | 0.42% | +$438.8K |
| Newamsterdam Pharma CompanyW EXP 99 99 999 *W EXP 99/99/999 | 245,000 | 245,000 | 0 | $1.96M | $4.19M | 0.39% | +$2.23M |
| Celcuity Inc.NOTE 2 750 8 0(CELC) | 0 | 0 | 0 | $0 | $4.00M | 0.37% | +$4.00M |
| Perceptive Cap Solutions CorCL A CL A ORD SHS | 350,000 | 350,000 | 0 | $3.71M | $3.76M | 0.35% | +$42.0K |
| Inspire Medical Systems, Inc.(INSP) | 0 | 50,000 | +50,000 | $0 | $3.71M | 0.35% | +$3.71M |
| Ovid Therapeutics Inc.(OVID) | 667,516 | 2,650,000 | +1,982,484 | $220.2K | $3.44M | 0.32% | +$3.22M |
| BridgeBio Pharma, Inc.(BBIO) | 150,000 | 65,000 | -85,000 | $6.48M | $3.38M | 0.31% | -$3.10M |
| Jazz Pharmaceuticals plcSHS USD(JAZZ) | 25,000 | 25,000 | 0 | $2.65M | $3.29M | 0.31% | +$642.0K |
| Crinetics Pharmaceuticals In | 152,252 | 75,000 | -77,252 | $4.38M | $3.12M | 0.29% | -$1.26M |
| MBX Biosciences, Inc.(MBX) | 0 | 165,000 | +165,000 | $0 | $2.89M | 0.27% | +$2.89M |
| Autolus Therapeutics plcADS(AUTL) | 3,045,000 | 1,750,000 | -1,295,000 | $6.94M | $2.85M | 0.27% | -$4.09M |
| Ocular Therapeutix, Inc.(OCUL) | 0 | 239,000 | +239,000 | $0 | $2.79M | 0.26% | +$2.79M |
| Oaktree Acquisition Corp IiiUNIT 10 04 2029 UNIT 10/04/2029 | 250,000 | 250,000 | 0 | $2.65M | $2.66M | 0.25% | +$5.0K |
| Climb Bio, Inc.(CLYM) | 1,500,000 | 1,300,000 | -200,000 | $1.86M | $2.61M | 0.24% | +$753.0K |
| Olema Pharmaceuticals, Inc.(OLMA) | 250,000 | 250,000 | 0 | $1.06M | $2.45M | 0.23% | +$1.38M |
| Sagimet Biosciences Inc.COM SER A(SGMT) | 0 | 350,000 | +350,000 | $0 | $2.40M | 0.22% | +$2.40M |
| Astria Therapeutics Inc | 300,000 | 300,000 | 0 | $1.61M | $2.18M | 0.20% | +$576.0K |
| United Therapeutics Corporation(UTHR) | 0 | 5,000 | +5,000 | $0 | $2.10M | 0.20% | +$2.10M |
| Geron Corporation(GERN) | 1,500,000 | 1,500,000 | 0 | $2.12M | $2.06M | 0.19% | -$60.0K |
| Anteris Technologies Global Corp.(AVR) | 425,000 | 450,000 | +25,000 | $1.61M | $2.02M | 0.19% | +$414.3K |
| Orchestra BioMed Holdings, Inc.(OBIO) | 0 | 727,272 | +727,272 | $0 | $1.80M | 0.17% | +$1.80M |
| Eupraxia Pharmaceuticals Inc.(EPRX) | 0 | 300,000 | +300,000 | $0 | $1.77M | 0.16% | +$1.77M |
| Cullinan Therapeutics, Inc.(CGEM) | 263,817 | 263,817 | 0 | $1.99M | $1.56M | 0.15% | -$422.1K |
| Milestone Pharmaceuticals Inc.(MIST) | 0 | 666,666 | +666,666 | $0 | $1.33M | 0.12% | +$1.33M |
| COMPASS Pathways plcADS(CMPS) | 0 | 200,000 | +200,000 | $0 | $1.15M | 0.11% | +$1.15M |
| Nextcure Inc | 0 | 191,882 | +191,882 | $0 | $1.12M | 0.10% | +$1.12M |
| Perspective Therapeutics, Inc.(CATX) | 1,050,000 | 300,000 | -750,000 | $3.61M | $1.03M | 0.10% | -$2.58M |
| Sutro Biopharma, Inc.(STRO) | 752,722 | 752,722 | 0 | $537.4K | $653.7K | 0.06% | +$116.3K |
| Jade Biosciences Inc | 65,317 | 65,317 | 0 | $652.5K | $563.7K | 0.05% | -$88.8K |
| Engene Holdings Inc COM | 77,000 | 77,000 | 0 | $280.3K | $525.9K | 0.05% | +$245.6K |
| Context Therapeutics Inc.(CNTX) | 518,025 | 402,653 | -115,372 | $339.4K | $390.1K | 0.04% | +$50.7K |
| Repare Therapeutics Inc | 200,000 | 200,000 | 0 | $278.0K | $352.0K | 0.03% | +$74.0K |
| Crescent Biopharma, Inc.(CBIO) | 280,031 | 17,998 | -262,033 | $4.52M | $214.0K | 0.02% | -$4.31M |
| Adagio Medical Holdings, Inc.(ADGM) | 80,000 | 80,000 | 0 | $108.0K | $155.2K | 0.01% | +$47.2K |
| Q32 Bio Inc.(QTTB) | 27,777 | 27,777 | 0 | $41.4K | $55.0K | 0.01% | +$13.6K |
| ARS Pharmaceuticals, Inc.(SPRY) | 0 | 2,500 | +2,500 | $0 | $25.1K | 0.00% | +$25.1K |
| Rocket Pharmaceuticals, Inc.W EXP 09 02 202(RCKT) | 75,000 | 75,000 | 0 | $2.2K | $3.0K | 0.00% | +$833 |
| Axsome Therapeutics, Inc.(AXSM) | 50,000 | 0 | -50,000 | $5.22M | $0 | — | -$5.22M |
| Blueprint Medicines Corp | 250,000 | 0 | -250,000 | $32.05M | $0 | — | -$32.05M |
| Immatics N.VW EXP 07 01 202 | 187,204 | 0 | -187,204 | $112 | $0 | — | -$112 |
| Inozyme Pharma Inc | 1,749,359 | 0 | -1,749,359 | $7.00M | $0 | — | -$7.00M |
| Mirum Pharmaceuticals, Inc.(MIRM) | 24,692 | 0 | -24,692 | $1.26M | $0 | — | -$1.26M |
| Nextcure Inc | 2,302,598 | 0 | -2,302,598 | $1.06M | $0 | — | -$1.06M |
| Nkarta, Inc.(NKTX) | 800,000 | 0 | -800,000 | $1.33M | $0 | — | -$1.33M |
| OnKure Therapeutics, Inc.CL A(OKUR) | 347,990 | 0 | -347,990 | $831.7K | $0 | — | -$831.7K |
| Radiopharm Theranostics LimitedADS(RADX) | 35,635 | 0 | -35,635 | $166.1K | $0 | — | -$166.1K |
| Rapport Therapeutics, Inc.(RAPP) | 199,643 | 0 | -199,643 | $2.27M | $0 | — | -$2.27M |
| Third Harmonic Bio Inc | 370,000 | 0 | -370,000 | $2.01M | $0 | — | -$2.01M |