Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2023 ▲▼ | Q1 2024 ▲▼ | Change ▲▼ | Q4 2023 ▲▼ | Q1 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| CORBUS PHARMACEUTICALS HLDGS(CRBP) | 195,899 | 559,271 | +363,372 | 1,183 | 21,946 | 5.97% | +20,763 |
| TARSUS PHARMACEUTICALS INC(TARS) | 518,519 | 710,277 | +191,758 | 10,500 | 25,819 | 7.02% | +15,319 |
| AEROVATE THERAPEUTICS INC | 0 | 367,965 | +367,965 | 0 | 10,881 | 2.96% | +10,881 |
| ALNYLAM PHARMACEUTICALS INC(ALNY) | 0 | 51,541 | +51,541 | 0 | 7,703 | 2.10% | +7,703 |
| CYTOKINETICS INC(CYTK) | 30,000 | 145,147 | +115,147 | 2,505 | 10,176 | 2.77% | +7,672 |
| PYXIS ONCOLOGY INC(PYXS) | 0 | 1,662,408 | +1,662,408 | 0 | 7,082 | 1.93% | +7,082 |
| SAREPTA THERAPEUTICS INC(SRPT) | 132,640 | 152,278 | +19,638 | 12,790 | 19,714 | 5.36% | +6,923 |
| CRINETICS PHARMACEUTICALS IN(CRNX) | 680,370 | 643,751 | -36,619 | 24,208 | 30,134 | 8.20% | +5,926 |
| ARCUTIS BIOTHERAPEUTICS INC(ARQT) | 0 | 589,642 | +589,642 | 0 | 5,843 | 1.59% | +5,843 |
| PRAXIS PRECISION MEDICINES I(PRAX) | 200,000 | 168,388 | -31,612 | 4,456 | 10,275 | 2.79% | +5,819 |
| VERONA PHARMA PLC | 367,468 | 375,310 | +7,842 | 257 | 6,039 | 1.64% | +5,781 |
| CYBIN INC(HELP) | 0 | 13,953,488 | +13,953,488 | 0 | 5,770 | 1.57% | +5,770 |
| CERVOMED INC(CRVO) | 0 | 237,345 | +237,345 | 0 | 5,530 | 1.50% | +5,530 |
| SCHOLAR ROCK HLDG CORP(SRRK) | 0 | 291,701 | +291,701 | 0 | 5,181 | 1.41% | +5,181 |
| MACROGENICS INC(MGNX) | 0 | 318,167 | +318,167 | 0 | 4,683 | 1.27% | +4,683 |
| XENON PHARMACEUTICALS INC(XENE) | 0 | 107,187 | +107,187 | 0 | 4,614 | 1.26% | +4,614 |
| NURIX THERAPEUTICS INC(NRIX) | 0 | 300,000 | +300,000 | 0 | 4,410 | 1.20% | +4,410 |
| WAVE LIFE SCIENCES LTD(WVE) | 0 | 590,088 | +590,088 | 0 | 3,641 | 0.99% | +3,641 |
| ABEONA THERAPEUTICS INC(ABEO) | 600,000 | 888,593 | +288,593 | 3,006 | 6,442 | 1.75% | +3,436 |
| JASPER THERAPEUTICS INC(JSPR) | 0 | 105,175 | +105,175 | 0 | 3,088 | 0.84% | +3,088 |
| VENTYX BIOSCIENCES INC | 5,914 | 507,647 | +501,733 | 15 | 2,792 | 0.76% | +2,777 |
| TOURMALINE BIO INC | 0 | 108,483 | +108,483 | 0 | 2,484 | 0.68% | +2,484 |
| IBIO INC(IBIO) | 0 | 600,000 | +600,000 | 0 | 2,436 | 0.66% | +2,436 |
| SAGIMET BIOSCIENCES INC(SGMT) | 0 | 412,565 | +412,565 | 0 | 2,236 | 0.61% | +2,236 |
| IMMUNIC INC(IMUX) | 0 | 1,612,378 | +1,612,378 | 0 | 2,128 | 0.58% | +2,128 |
| LENZ THERAPEUTICS INC(LENZ) | 0 | 85,000 | +85,000 | 0 | 1,898 | 0.52% | +1,898 |
| ACHILLES THERAPEUTICS PLC | 0 | 1,443,181 | +1,443,181 | 0 | 1,804 | 0.49% | +1,804 |
| INSMED INC(INSM) | 0 | 51,335 | +51,335 | 0 | 1,393 | 0.38% | +1,393 |
| RAPT THERAPEUTICS INC | 0 | 154,625 | +154,625 | 0 | 1,389 | 0.38% | +1,389 |
| UNIQURE NV(QURE) | 157,365 | 469,133 | +311,768 | 1,065 | 2,439 | 0.66% | +1,374 |
| KODIAK SCIENCES INC(KOD) | 412,881 | 476,586 | +63,705 | 1,255 | 2,507 | 0.68% | +1,252 |
| AEON BIOPHARMA INC | 257,977 | 257,977 | 0 | 1,857 | 2,993 | 0.81% | +1,135 |
| ALPINE IMMUNE SCIENCES INC | 487,248 | 261,365 | -225,883 | 9,287 | 10,361 | 2.82% | +1,074 |
| AVALO THERAPEUTICS INC(AVTX) | 0 | 46,648 | +46,648 | 0 | 1,015 | 0.28% | +1,015 |
| ROCKET PHARMACEUTICALS INC(RCKT) | 239,726 | 297,096 | +57,370 | 7,185 | 8,004 | 2.18% | +819 |
| NYXOAH S A SHS | 0 | 50,699 | +50,699 | 0 | 684 | 0.19% | +684 |
| VERU INC(VERU) | 0 | 946,382 | +946,382 | 0 | 663 | 0.18% | +663 |
| MIND MEDICINE MINDMED INC | 600,000 | 297,481 | -302,519 | 2,196 | 2,796 | 0.76% | +600 |
| LARIMAR THERAPEUTICS INC(LRMR) | 602,868 | 438,528 | -164,340 | 2,743 | 3,328 | 0.91% | +585 |
| ALLAKOS INC | 237,056 | 932,675 | +695,619 | 647 | 1,175 | 0.32% | +528 |
| PROTARA THERAPEUTICS INC(TARA) | 188,664 | 202,701 | +14,037 | 353 | 813 | 0.22% | +460 |
| NUVATION BIO INC(NUVB) | 1,222,852 | 633,282 | -589,570 | 1,847 | 2,305 | 0.63% | +459 |
| SOLENO THERAPEUTICS INC | 590,243 | 565,411 | -24,832 | 23,757 | 24,200 | 6.58% | +442 |
| Q32 BIO INC(FIXX) | 0 | 22,335 | +22,335 | 0 | 381 | 0.10% | +381 |
| KARYOPHARM THERAPEUTICS INC(KPTI) | 400,000 | 409,355 | +9,355 | 346 | 618 | 0.17% | +272 |
| PROQR THRAPEUTICS N V SHS EURO | 472,625 | 483,583 | +10,958 | 936 | 1,098 | 0.30% | +162 |
| ELEVATION ONCOLOGY INC | 1,171,939 | 148,089 | -1,023,850 | 629 | 760 | 0.21% | +130 |
| ANEBULO PHARMACEUTICALS INC | 157,862 | 157,862 | 0 | 382 | 453 | 0.12% | +71 |
| MILESTONE PHARMACEUTICALS IN(MIST) | 462,828 | 466,019 | +3,191 | 773 | 834 | 0.23% | +61 |
| CHEMOMAB THERAPEUTICS LTD | 213,392 | 213,392 | 0 | 109 | 166 | 0.05% | +57 |
| STOKE THERAPEUTICS INC(STOK) | 12,116 | 6,816 | -5,300 | 64 | 92 | 0.03% | +28 |
| BRAINSTORM CELL THERAPEUTICS | 90,242 | 90,242 | 0 | 25 | 51 | 0.01% | +26 |
| RELMADA THERAPEUTICS INC(RLMD) | 40,369 | 40,369 | 0 | 167 | 188 | 0.05% | +21 |
| APELLIS PHARMACEUTICALS INC COM | 34,361 | 35,092 | +731 | 2,057 | 2,063 | 0.56% | +6 |
| IMMATICS N.V(IMTX) | 49,031 | 49,415 | +384 | 516 | 519 | 0.14% | +3 |
| LYRA THERAPEUTICS INC | 1,254,384 | 1,056,829 | -197,555 | 6,573 | 6,573 | 1.79% | +1 |
| ASLAN PHARMACEUTICALS LTD | 35,420 | 35,420 | 0 | 7 | 6 | 0.00% | -0 |
| FINCH THERAPEUTICS GROUP INC | 6,892 | 6,892 | 0 | 25 | 18 | 0.00% | -7 |
| AVROBIO INC | 718,259 | 754,061 | +35,802 | 977 | 965 | 0.26% | -12 |
| ACLARIS THERAPEUTICS INC(ACRS) | 19,482 | 0 | -19,482 | 20 | 0 | — | -20 |
| KEZAR LIFE SCIENCES INC | 853,391 | 868,992 | +15,601 | 809 | 783 | 0.21% | -25 |
| INFLARX NV(IFRX) | 688,604 | 704,987 | +16,383 | 1,122 | 1,086 | 0.30% | -37 |
| SYNLOGIC INC(SYBX) | 20,448 | 20,448 | 0 | 79 | 37 | 0.01% | -42 |
| TEMPEST THERAPEUTICS INC(TPST) | 105,600 | 105,600 | 0 | 465 | 413 | 0.11% | -52 |
| HOOKIPA PHARMA INC | 530,776 | 530,776 | 0 | 430 | 378 | 0.10% | -52 |
| ACUMEN PHARMACEUTICALS INC(ABOS) | 315,265 | 266,435 | -48,830 | 1,211 | 1,079 | 0.29% | -132 |
| CATALYST PHARMACEUTICALS INC | 505,862 | 518,386 | +12,524 | 8,504 | 8,263 | 2.25% | -240 |
| TRACON PHARMACEUTICALS INC | 2,765,530 | 0 | -2,765,530 | 484 | 0 | — | -484 |
| TERNS PHARMACEUTICALS INC | 165,480 | 88,497 | -76,983 | 1,074 | 581 | 0.16% | -493 |
| STRUCTURE THERAPEUTICS INC | 14,524 | 0 | -14,524 | 592 | 0 | — | -592 |
| ROIVANT SCIENCES LTD(ROIV) | 151,821 | 100,609 | -51,212 | 1,705 | 1,060 | 0.29% | -645 |
| TYRA BIOSCIENCES INC(TYRA) | 48,170 | 501 | -47,669 | 667 | 8 | 0.00% | -659 |
| RENEO PHARMACEUTICALS INC | 421,300 | 0 | -421,300 | 674 | 0 | — | -674 |
| IMMUNOVANT INC(IMVT) | 233,394 | 276,925 | +43,531 | 9,833 | 8,947 | 2.43% | -885 |
| VOYAGER THERAPEUTICS INC(VYGR) | 305,857 | 180,857 | -125,000 | 2,581 | 1,684 | 0.46% | -898 |
| ASTRIA THERAPEUTICS INC | 374,807 | 140,687 | -234,120 | 2,879 | 1,980 | 0.54% | -898 |
| LANTHEUS HLDGS INC(LNTH) | 15,000 | 0 | -15,000 | 930 | 0 | — | -930 |
| ESPERION THERAPEUTICS INC NE | 337,636 | 0 | -337,636 | 1,010 | 0 | — | -1,010 |
| COHERUS BIOSCIENCES INC(CHRS) | 340,787 | 0 | -340,787 | 1,135 | 0 | — | -1,135 |
| BLACK DIAMOND THERAPEUTICS I | 555,572 | 0 | -555,572 | 1,561 | 0 | — | -1,561 |
| AUTOLUS THERAPEUTICS PLC(AUTL) | 262,694 | 0 | -262,694 | 1,692 | 0 | — | -1,692 |
| ANNEXON INC(ANNX) | 2,650,000 | 1,405,000 | -1,245,000 | 12,031 | 10,074 | 2.74% | -1,957 |
| ITEOS THERAPEUTICS INC | 346,471 | 101,325 | -245,146 | 3,794 | 1,382 | 0.38% | -2,412 |
| MODERNA INC(MRNA) | 24,546 | 0 | -24,546 | 2,441 | 0 | — | -2,441 |
| IMMUNOGEN INC | 90,162 | 0 | -90,162 | 2,673 | 0 | — | -2,673 |
| EDGEWISE THERAPEUTICS INC(EWTX) | 270,000 | 0 | -270,000 | 2,954 | 0 | — | -2,954 |
| MARINUS PHARMACEUTICALS INC | 746,069 | 537,925 | -208,144 | 8,110 | 4,863 | 1.32% | -3,247 |
| DYNE THERAPEUTICS INC(DYN) | 285,900 | 0 | -285,900 | 3,802 | 0 | — | -3,802 |
| ACELYRIN INC | 1,991,005 | 1,564,340 | -426,665 | 14,853 | 10,559 | 2.87% | -4,294 |
| CRISPR THERAPEUTICS AG(CRSP) | 70,546 | 0 | -70,546 | 4,416 | 0 | — | -4,416 |
| FUSION PHARMACEUTICALS INC | 500,000 | 0 | -500,000 | 4,805 | 0 | — | -4,805 |
| CABALETTA BIO INC(CABA) | 216,620 | 0 | -216,620 | 4,917 | 0 | — | -4,917 |
| LONGBOARD PHARMACEUTICALS IN | 979,462 | 236 | -979,226 | 5,906 | 5 | 0.00% | -5,901 |
| ICOSAVAX INC | 440,000 | 0 | -440,000 | 6,934 | 0 | — | -6,934 |
| PROTAGONIST THERAPEUTICS INC | 319,000 | 0 | -319,000 | 7,315 | 0 | — | -7,315 |
| EYEPOINT PHARMACEUTICALS INC(EYPT) | 368,130 | 1,047 | -367,083 | 8,507 | 22 | 0.01% | -8,486 |
| DISC MEDICINE INC(IRON) | 194,982 | 25,372 | -169,610 | 11,262 | 1,580 | 0.43% | -9,682 |
| BRIDGEBIO PHARMA INC(BBIO) | 473,126 | 282,013 | -191,113 | 19,100 | 8,720 | 2.37% | -10,380 |
| NUVALENT INC | 258,142 | 101,601 | -156,541 | 18,997 | 7,629 | 2.08% | -11,367 |
| AMYLYX PHARMACEUTICALS INC(AMLX) | 877,500 | 331,451 | -546,049 | 12,917 | 941 | 0.26% | -11,975 |