Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2024 ▲▼ | Q1 2025 ▲▼ | Change ▲▼ | Q4 2024 ▲▼ | Q1 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| SPDR S&P 500 ETF TR(SPY) | 0 | 25,000 | +25,000 | 0 | 13,985 | 4.56% | +13,985 |
| AKERO THERAPEUTICS INC | 0 | 245,000 | +245,000 | 0 | 9,918 | 3.23% | +9,918 |
| ALNYLAM PHARMACEUTICALS INC(ALNY) | 0 | 31,594 | +31,594 | 0 | 8,531 | 2.78% | +8,531 |
| VAXCYTE INC(PCVX) | 0 | 200,000 | +200,000 | 0 | 7,552 | 2.46% | +7,552 |
| SAREPTA THERAPEUTICS INC(SRPT) | 34,087 | 169,087 | +135,000 | 4,145 | 10,791 | 3.52% | +6,646 |
| EDGEWISE THERAPEUTICS INC(EWTX) | 0 | 280,000 | +280,000 | 0 | 6,160 | 2.01% | +6,160 |
| PRAXIS PRECISION MEDICINES I(PRAX) | 0 | 145,502 | +145,502 | 0 | 5,510 | 1.80% | +5,510 |
| VERONA PHARMA PLC | 80,000 | 130,000 | +50,000 | 3,715 | 8,254 | 2.69% | +4,539 |
| METSERA INC | 0 | 150,000 | +150,000 | 0 | 4,083 | 1.33% | +4,083 |
| NEURONETICS INC(STIM) | 0 | 1,100,000 | +1,100,000 | 0 | 4,048 | 1.32% | +4,048 |
| CIDARA THERAPEUTICS INC | 53,940 | 248,940 | +195,000 | 1,450 | 5,362 | 1.75% | +3,912 |
| DYNE THERAPEUTICS INC(DYN) | 0 | 358,837 | +358,837 | 0 | 3,753 | 1.22% | +3,753 |
| MAZE THERAPEUTICS INC(MAZE) | 0 | 322,740 | +322,740 | 0 | 3,553 | 1.16% | +3,553 |
| CUMBERLAND PHARMACEUTICALS I(CPIX) | 0 | 740,000 | +740,000 | 0 | 3,130 | 1.02% | +3,130 |
| KEROS THERAPEUTICS INC(KROS) | 0 | 274,009 | +274,009 | 0 | 2,792 | 0.91% | +2,792 |
| TREVI THERAPEUTICS INC(TRVI) | 325,000 | 575,000 | +250,000 | 1,339 | 3,617 | 1.18% | +2,278 |
| ORUKA THERAPEUTICS INC(ORKA) | 0 | 175,000 | +175,000 | 0 | 1,795 | 0.58% | +1,795 |
| ARVINAS INC(ARVN) | 0 | 229,900 | +229,900 | 0 | 1,614 | 0.53% | +1,614 |
| APELLIS PHARMACEUTICALS INC COM | 3,594 | 75,000 | +71,406 | 115 | 1,640 | 0.53% | +1,526 |
| VISTAGEN THERAPEUTICS INC(VTGN) | 77,616 | 601,703 | +524,087 | 229 | 1,504 | 0.49% | +1,275 |
| VIKING THERAPEUTICS INC(VKTX) | 0 | 50,000 | +50,000 | 0 | 1,208 | 0.39% | +1,208 |
| TELADOC HEALTH INC(TDOC) | 0 | 150,000 | +150,000 | 0 | 1,194 | 0.39% | +1,194 |
| IBIO INC(IBIO) | 599,913 | 599,913 | 0 | 1,470 | 2,412 | 0.79% | +942 |
| NUVATION BIO INC(NUVB) | 83,407 | 619,258 | +535,851 | 222 | 1,090 | 0.36% | +868 |
| SOLID BIOSCIENCES INC | 0 | 230,000 | +230,000 | 0 | 851 | 0.28% | +851 |
| 89BIO INC | 0 | 100,000 | +100,000 | 0 | 727 | 0.24% | +727 |
| VERVE THERAPEUTICS INC | 169,991 | 358,393 | +188,402 | 959 | 1,638 | 0.53% | +679 |
| ALPHA COGNITION INC(ACOG) | 755,867 | 967,867 | +212,000 | 4,452 | 5,110 | 1.66% | +658 |
| CHANNEL THERAPEUTICS CORPORA | 0 | 440,849 | +440,849 | 0 | 626 | 0.20% | +626 |
| GINKGO BIOWORKS HOLDINGS INC(DNA) | 0 | 58,300 | +58,300 | 0 | 332 | 0.11% | +332 |
| VIR BIOTECHNOLOGY INC(VIR) | 897,862 | 1,068,062 | +170,200 | 6,590 | 6,921 | 2.25% | +331 |
| ULTRAGENYX PHARMACEUTICAL IN(RARE) | 178,989 | 216,989 | +38,000 | 7,530 | 7,857 | 2.56% | +327 |
| GERON CORP(GERN) | 0 | 150,000 | +150,000 | 0 | 239 | 0.08% | +239 |
| PEPGEN INC(PEPG) | 0 | 150,000 | +150,000 | 0 | 211 | 0.07% | +211 |
| OLEMA PHARMACEUTICALS INC(OLMA) | 91,994 | 191,994 | +100,000 | 536 | 722 | 0.24% | +186 |
| EVAXION BIOTECH A/S(EVAX) | 0 | 80,000 | +80,000 | 0 | 148 | 0.05% | +148 |
| THERIVA BIOLOGICS INC(TOVX) | 0 | 120,031 | +120,031 | 0 | 132 | 0.04% | +132 |
| KARYOPHARM THERAPEUTICS INC(KPTI) | 0 | 27,257 | +27,257 | 0 | 102 | 0.03% | +102 |
| MONOPAR THERAPEUTICS INC(MNPR) | 5,908 | 5,908 | 0 | 130 | 215 | 0.07% | +85 |
| VERU INC(VERU) | 945,239 | 1,425,239 | +480,000 | 615 | 699 | 0.23% | +84 |
| ALPHA TEKNOVA INC(TKNO) | 0 | 14,008 | +14,008 | 0 | 73 | 0.02% | +73 |
| DELCATH SYS INC(DCTH) | 100,365 | 100,365 | 0 | 1,208 | 1,278 | 0.42% | +69 |
| NEUMORA THERAPEUTICS INC.(NMRA) | 0 | 15,457 | +15,457 | 0 | 15 | 0.01% | +15 |
| GALECTIN THERAPEUTICS INC(GALT) | 100 | 0 | -100 | 0 | 0 | — | -0 |
| 4D MOLECULAR THERAPEUTICS IN | 40 | 0 | -40 | 0 | 0 | — | -0 |
| GLYCOMIMETICS INC | 6,501 | 0 | -6,501 | 2 | 0 | — | -2 |
| SYNLOGIC INC(SYBX) | 20,422 | 20,422 | 0 | 28 | 25 | 0.01% | -3 |
| CYTOMX THERAPEUTICS INC(CTMX) | 8,924 | 0 | -8,924 | 9 | 0 | — | -9 |
| RELMADA THERAPEUTICS INC(RLMD) | 40,270 | 40,270 | 0 | 21 | 11 | 0.00% | -10 |
| CANDEL THERAPEUTICS INC(CADL) | 1,400 | 0 | -1,400 | 12 | 0 | — | -12 |
| BRAINSTORM CELL THERAPEUTICS | 6,016 | 0 | -6,016 | 14 | 0 | — | -14 |
| SAGIMET BIOSCIENCES INC(SGMT) | 11,984 | 11,984 | 0 | 54 | 39 | 0.01% | -15 |
| IMMUNOVANT INC(IMVT) | 600 | 0 | -600 | 15 | 0 | — | -15 |
| AUTONOMIX MED INC(AMIX) | 20,000 | 20,000 | 0 | 75 | 35 | 0.01% | -40 |
| HOOKIPA PHARMA INC | 52,996 | 52,996 | 0 | 107 | 57 | 0.02% | -49 |
| INHIBRX BIOSCIENCES INC(INBX) | 42,122 | 42,122 | 0 | 649 | 589 | 0.19% | -59 |
| ANEBULO PHARMACEUTICALS INC | 157,720 | 157,720 | 0 | 265 | 205 | 0.07% | -60 |
| MIND MEDICINE MINDMED INC | 62,691 | 62,691 | 0 | 436 | 367 | 0.12% | -70 |
| STOKE THERAPEUTICS INC(STOK) | 6,798 | 0 | -6,798 | 75 | 0 | — | -75 |
| LYRA THERAPEUTICS INC | 1,058,148 | 1,058,148 | 0 | 218 | 134 | 0.04% | -85 |
| TEMPEST THERAPEUTICS INC(TPST) | 105,285 | 0 | -105,285 | 88 | 0 | — | -88 |
| LARIMAR THERAPEUTICS INC(LRMR) | 58,526 | 58,526 | 0 | 226 | 126 | 0.04% | -101 |
| CLIMB BIO INC(CLYM) | 175,088 | 175,088 | 0 | 315 | 214 | 0.07% | -102 |
| VOYAGER THERAPEUTICS INC(VYGR) | 55,766 | 55,766 | 0 | 316 | 188 | 0.06% | -128 |
| SPRUCE BIOSCIENCES INC | 1,000,000 | 1,000,000 | 0 | 420 | 290 | 0.09% | -130 |
| ITEOS THERAPEUTICS INC | 78,585 | 78,585 | 0 | 604 | 469 | 0.15% | -134 |
| AEON BIOPHARMA INC | 257,563 | 0 | -257,563 | 139 | 0 | — | -139 |
| SENSEI BIOTHERAPEUTICS INC(FTH) | 649,963 | 449,963 | -200,000 | 319 | 177 | 0.06% | -141 |
| CHEMOMAB THERAPEUTICS LTD | 213,052 | 213,052 | 0 | 386 | 232 | 0.08% | -153 |
| BIOMX INC(PHGE) | 892,976 | 892,976 | 0 | 652 | 496 | 0.16% | -156 |
| MACROGENICS INC(MGNX) | 80,071 | 80,071 | 0 | 260 | 102 | 0.03% | -159 |
| ACUMEN PHARMACEUTICALS INC(ABOS) | 265,769 | 265,769 | 0 | 457 | 292 | 0.10% | -165 |
| QUOIN PHARMACEUTICALS LTD | 275,000 | 0 | -275,000 | 179 | 0 | — | -179 |
| KEZAR LIFE SCIENCES INC COM NEW | 106,901 | 106,901 | 0 | 718 | 522 | 0.17% | -197 |
| AETHLON MED INC | 750,000 | 1,229,285 | +479,285 | 645 | 440 | 0.14% | -205 |
| ELEVATION ONCOLOGY INC | 690,050 | 690,050 | 0 | 388 | 179 | 0.06% | -209 |
| KARYOPHARM THERAPEUTICS INC(KPTI) | 408,899 | 0 | -408,899 | 277 | 0 | — | -277 |
| AVENUE THERAPEUTICS INC | 140,000 | 0 | -140,000 | 280 | 0 | — | -280 |
| TOURMALINE BIO INC | 67,927 | 67,927 | 0 | 1,378 | 1,033 | 0.34% | -344 |
| LYELL IMMUNOPHARMA INC(LYEL) | 1,276,037 | 876,037 | -400,000 | 817 | 471 | 0.15% | -345 |
| PERSPECTIVE THERAPEUTICS INC(CATX) | 108,300 | 0 | -108,300 | 345 | 0 | — | -345 |
| PYXIS ONCOLOGY INC(PYXS) | 613,253 | 613,253 | 0 | 957 | 601 | 0.20% | -356 |
| FULCRUM THERAPEUTICS INC(FULC) | 200,096 | 200,096 | 0 | 940 | 576 | 0.19% | -364 |
| TRAVERE THERAPEUTICS INC(TVTX) | 22,600 | 0 | -22,600 | 394 | 0 | — | -394 |
| VIGIL NEUROSCIENCE INC | 500,000 | 250,000 | -250,000 | 850 | 445 | 0.14% | -405 |
| ABEONA THERAPEUTICS INC(ABEO) | 533,581 | 533,581 | 0 | 2,972 | 2,540 | 0.83% | -432 |
| TG THERAPEUTICS INC(TGTX) | 291,240 | 210,065 | -81,175 | 8,766 | 8,283 | 2.70% | -483 |
| LEXICON PHARMACEUTICALS INC(LXRX) | 1,550,000 | 1,417,952 | -132,048 | 1,145 | 653 | 0.21% | -491 |
| JANUX THERAPEUTICS INC(JANX) | 74,691 | 129,691 | +55,000 | 3,999 | 3,502 | 1.14% | -497 |
| TYRA BIOSCIENCES INC(TYRA) | 60,000 | 35,000 | -25,000 | 834 | 326 | 0.11% | -508 |
| SANA BIOTECHNOLOGY INC(SANA) | 365,000 | 0 | -365,000 | 595 | 0 | — | -595 |
| CORBUS PHARMACEUTICALS HLDGS(CRBP) | 51,431 | 0 | -51,431 | 607 | 0 | — | -607 |
| IMMUNIC INC(IMUX) | 1,614,170 | 914,170 | -700,000 | 1,614 | 996 | 0.32% | -618 |
| ALECTOR INC | 950,000 | 950,000 | 0 | 1,796 | 1,169 | 0.38% | -627 |
| ACLARIS THERAPEUTICS INC(ACRS) | 350,000 | 150,900 | -199,100 | 868 | 231 | 0.08% | -637 |
| CARTESIAN THERAPEUTICS INC(RNAC) | 52,166 | 22,166 | -30,000 | 934 | 292 | 0.10% | -642 |
| NURIX THERAPEUTICS INC(NRIX) | 34,985 | 0 | -34,985 | 659 | 0 | — | -659 |
| SANGAMO THERAPEUTICS INC(SGMOQ) | 1,860,179 | 1,860,179 | 0 | 1,897 | 1,220 | 0.40% | -677 |
| THIRD HARMONIC BIO INC | 100,000 | 100,000 | 0 | 1,029 | 347 | 0.11% | -682 |
| AMYLYX PHARMACEUTICALS INC(AMLX) | 201,187 | 0 | -201,187 | 760 | 0 | — | -760 |