Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| KODIAK SCIENCES INC(KOD) | 719,787 | 1,265,795 | +546,008 | 20,125 | 48,252 | 6.90% | +28,127 |
| ALUMIS INC | 0 | 1,213,548 | +1,213,548 | 0 | 26,734 | 3.82% | +26,734 |
| CELLDEX THERAPEUTICS INC NEW(CLDX) | 0 | 461,247 | +461,247 | 0 | 14,631 | 2.09% | +14,631 |
| TERNS PHARMACEUTICALS INC | 1,596,378 | 1,456,378 | -140,000 | 64,494 | 76,780 | 10.98% | +12,287 |
| BRIDGEBIO PHARMA INC(BBIO) | 0 | 160,120 | +160,120 | 0 | 11,891 | 1.70% | +11,891 |
| ORUKA THERAPEUTICS INC(ORKA) | 0 | 242,021 | +242,021 | 0 | 11,871 | 1.70% | +11,871 |
| ANI PHARMACEUTICALS INC(ANIP) | 0 | 147,085 | +147,085 | 0 | 11,311 | 1.62% | +11,311 |
| HARROW INC(HROW) | 183,347 | 543,047 | +359,700 | 8,984 | 19,148 | 2.74% | +10,164 |
| ULTRAGENYX PHARMACEUTICAL IN(RARE) | 12,671 | 482,571 | +469,900 | 291 | 10,110 | 1.45% | +9,818 |
| SOLENO THERAPEUTICS INC | 68,823 | 344,123 | +275,300 | 3,187 | 11,521 | 1.65% | +8,335 |
| PALVELLA THERAPEUTICS INC NE(PVLA) | 0 | 64,626 | +64,626 | 0 | 8,056 | 1.15% | +8,056 |
| VERA THERAPEUTICS INC(VERA) | 0 | 200,000 | +200,000 | 0 | 8,046 | 1.15% | +8,046 |
| CYTOKINETICS INC(CYTK) | 172,672 | 283,572 | +110,900 | 10,972 | 18,690 | 2.67% | +7,719 |
| VAXCYTE INC(PCVX) | 378,682 | 428,682 | +50,000 | 17,472 | 24,911 | 3.56% | +7,438 |
| CONTINEUM THERAPEUTICS INC(CTNM) | 282,874 | 807,874 | +525,000 | 3,233 | 10,551 | 1.51% | +7,318 |
| OCUGEN INC(OCGN) | 0 | 3,962,972 | +3,962,972 | 0 | 7,173 | 1.03% | +7,173 |
| OVID THERAPEUTICS INC(OVID) | 247,558 | 2,894,704 | +2,647,146 | 404 | 6,426 | 0.92% | +6,023 |
| INVENTIVA SA(IVA) | 502,601 | 1,429,101 | +926,500 | 2,329 | 7,843 | 1.12% | +5,514 |
| TECTONIC THERAPEUTIC INC(TECX) | 0 | 157,537 | +157,537 | 0 | 4,869 | 0.70% | +4,869 |
| REVOLUTION MEDICINES INC(RVMD) | 138,142 | 163,142 | +25,000 | 11,003 | 15,866 | 2.27% | +4,863 |
| TENAX THERAPEUTICS INC(TENX) | 967,600 | 1,017,600 | +50,000 | 11,795 | 16,271 | 2.33% | +4,476 |
| EUPRAXIA PHARMACEUTICALS INC(EPRX) | 610,000 | 1,214,741 | +604,741 | 4,606 | 8,795 | 1.26% | +4,189 |
| RELMADA THERAPEUTICS INC(RLMD) | 3,068,359 | 2,688,359 | -380,000 | 14,820 | 18,711 | 2.68% | +3,891 |
| CARDIOL THERAPEUTICS INC(CRDL) | 0 | 2,725,000 | +2,725,000 | 0 | 3,679 | 0.53% | +3,679 |
| SURROZEN INC(SRZN) | 65,788 | 173,107 | +107,319 | 1,487 | 5,043 | 0.72% | +3,556 |
| ZURA BIO LTD(ZURA) | 802,322 | 1,193,492 | +391,170 | 4,204 | 7,101 | 1.02% | +2,897 |
| JADE BIOSCIENCES INC | 300,000 | 512,349 | +212,349 | 4,629 | 7,199 | 1.03% | +2,570 |
| LIPOCINE INC NEW(LPCN) | 199,542 | 508,556 | +309,014 | 1,602 | 4,063 | 0.58% | +2,461 |
| ALTO NEUROSCIENCE INC(ANRO) | 515,000 | 515,000 | 0 | 9,167 | 11,577 | 1.66% | +2,410 |
| DAMORA THERAPEUTICS INC(DMRA) | 285,710 | 335,710 | +50,000 | 6,574 | 8,695 | 1.24% | +2,121 |
| ANNEXON INC(ANNX) | 230,244 | 580,244 | +350,000 | 1,156 | 3,215 | 0.46% | +2,059 |
| ANTERIS TECHNOLOGIES GLOBAL(AVR) | 0 | 366,571 | +366,571 | 0 | 2,034 | 0.29% | +2,034 |
| ACUMEN PHARMACEUTICALS INC(ABOS) | 254,312 | 1,053,797 | +799,485 | 537 | 2,487 | 0.36% | +1,950 |
| ALECTOR INC | 2,082,606 | 2,082,606 | 0 | 3,249 | 4,478 | 0.64% | +1,229 |
| DEFINIUM THERAPEUTICS INC(DFTX) | 0 | 58,803 | +58,803 | 0 | 1,111 | 0.16% | +1,111 |
| BIOHAVEN LTD(BHVN) | 212,481 | 412,481 | +200,000 | 2,399 | 3,490 | 0.50% | +1,091 |
| SOLID BIOSCIENCES INC | 160,409 | 264,409 | +104,000 | 905 | 1,904 | 0.27% | +999 |
| COMPASS PATHWAYS PLC(CMPS) | 400,000 | 675,000 | +275,000 | 2,760 | 3,733 | 0.53% | +973 |
| DIREXION SHARES ETF TRUST DAI BIO BEA ETF | 40,822 | 105,822 | +65,000 | 860 | 1,725 | 0.25% | +865 |
| CENTESSA PHARMACEUTICALS PLC | 0 | 18,113 | +18,113 | 0 | 719 | 0.10% | +719 |
| PROMIS NEUROSCIENCES INC(PMN) | 0 | 55,000 | +55,000 | 0 | 699 | 0.10% | +699 |
| ACADIA PHARMACEUTICALS INC | 0 | 28,099 | +28,099 | 0 | 625 | 0.09% | +625 |
| PASSAGE BIO INC(PASG) | 0 | 68,124 | +68,124 | 0 | 535 | 0.08% | +535 |
| TRAWS PHARMA INC(TRAW) | 678,142 | 678,142 | 0 | 766 | 1,241 | 0.18% | +475 |
| CABALETTA BIO INC(CABA) | 900,000 | 900,000 | 0 | 1,971 | 2,421 | 0.35% | +450 |
| IMMUNIC INC(IMUX) | 674,662 | 674,662 | 0 | 360 | 749 | 0.11% | +389 |
| PHARVARIS N V COM | 486,856 | 486,856 | 0 | 13,510 | 13,754 | 1.97% | +243 |
| ADLAI NORTYE LTD(ANL) | 0 | 33,899 | +33,899 | 0 | 235 | 0.03% | +235 |
| NEUMORA THERAPEUTICS INC.(NMRA) | 1,278,408 | 1,278,408 | 0 | 2,288 | 2,493 | 0.36% | +205 |
| KALVISTA PHARMACEUTICALS INC | 35,119 | 35,119 | 0 | 567 | 707 | 0.10% | +140 |
| EQUILLIUM INC(EQ) | 303,555 | 303,555 | 0 | 471 | 607 | 0.09% | +137 |
| KEZAR LIFE SCIENCES INC COM NEW | 102,211 | 102,211 | 0 | 643 | 758 | 0.11% | +115 |
| DBV TECHNOLOGIES S A(DBVT) | 525,000 | 525,000 | 0 | 2,084 | 2,199 | 0.31% | +115 |
| MACROGENICS INC(MGNX) | 74,893 | 74,893 | 0 | 121 | 216 | 0.03% | +96 |
| KARYOPHARM THERAPEUTICS INC(KPTI) | 544,554 | 733,435 | +188,881 | 4,008 | 4,085 | 0.58% | +77 |
| LEXICON PHARMACEUTICALS INC(LXRX) | 164,674 | 164,674 | 0 | 189 | 257 | 0.04% | +68 |
| NEURONETICS INC(STIM) | 701,182 | 701,182 | 0 | 968 | 1,017 | 0.15% | +49 |
| HYPERLIQUID STRATEGIES INC(PURR) | 30,001 | 30,001 | 0 | 107 | 153 | 0.02% | +46 |
| BIOMX INC(PHGE) | 19,473 | 19,473 | 0 | 36 | 73 | 0.01% | +37 |
| AIRSCULPT TECHNOLOGIES INC | 16,398 | 16,398 | 0 | 32 | 46 | 0.01% | +14 |
| REZOLUTE INC(RZLT) | 16,479 | 16,479 | 0 | 39 | 50 | 0.01% | +11 |
| VERU INC(VERU) | 133,517 | 133,517 | 0 | 286 | 295 | 0.04% | +9 |
| NEUPHORIA THERAPEUTICS INC | 47,443 | 47,443 | 0 | 184 | 193 | 0.03% | +9 |
| VYNE THERAPEUTICS INC(YARW) | 264,912 | 264,912 | 0 | 154 | 158 | 0.02% | +5 |
| SILENCE THERAPEUTICS PLC(SLN) | 865,784 | 865,784 | 0 | 1,732 | 1,732 | 0.25% | 0 |
| PMV PHARMACEUTICALS INC(PMVP) | 89,136 | 89,136 | 0 | 111 | 111 | 0.02% | -1 |
| THERIVA BIOLOGICS INC(TOVX) | 112,076 | 112,076 | 0 | 24 | 22 | 0.00% | -2 |
| AUTONOMIX MED INC(AMIX) | 18,688 | 18,688 | 0 | 10 | 7 | 0.00% | -3 |
| VOYAGER THERAPEUTICS INC(VYGR) | 53,063 | 53,063 | 0 | 209 | 205 | 0.03% | -4 |
| CHEMOMAB THERAPEUTICS LTD(CMMB) | 51,793 | 51,793 | 0 | 85 | 81 | 0.01% | -4 |
| AETHLON MED INC(AEMD) | 14,364 | 14,364 | 0 | 40 | 31 | 0.00% | -8 |
| ANEBULO PHARMACEUTICALS INC | 17,736 | 0 | -17,736 | 18 | 0 | — | -18 |
| CARTESIAN THERAPEUTICS INC(RNAC) | 20,807 | 20,807 | 0 | 150 | 128 | 0.02% | -22 |
| SYNLOGIC INC(SYBX) | 19,966 | 0 | -19,966 | 22 | 0 | — | -22 |
| JASPER THERAPEUTICS INC(JSPR) | 24,093 | 24,093 | 0 | 44 | 21 | 0.00% | -23 |
| VIKING THERAPEUTICS INC(VKTX) | 9,717 | 9,717 | 0 | 342 | 316 | 0.05% | -26 |
| SENSEI BIOTHERAPEUTICS INC(FTH) | 21,351 | 6,351 | -15,000 | 228 | 200 | 0.03% | -28 |
| IBIO INC(IBIO) | 957,062 | 957,062 | 0 | 1,847 | 1,818 | 0.26% | -29 |
| IMMATICS N.V(IMTX) | 48,569 | 48,569 | 0 | 510 | 478 | 0.07% | -32 |
| VISTAGEN THERAPEUTICS INC(VTGN) | 519,077 | 519,077 | 0 | 344 | 297 | 0.04% | -47 |
| MANGOCEUTICALS INC(MGRX) | 138,146 | 138,146 | 0 | 102 | 50 | 0.01% | -52 |
| LYRA THERAPEUTICS INC | 21,161 | 0 | -21,161 | 65 | 0 | — | -65 |
| SHUTTLE PHARMACTCLS HLDGS IN | 68,993 | 68,993 | 0 | 124 | 47 | 0.01% | -77 |
| EVAXION AS(EVAX) | 74,698 | 74,698 | 0 | 356 | 278 | 0.04% | -78 |
| NYXOAH S A SHS | 47,358 | 47,358 | 0 | 218 | 138 | 0.02% | -80 |
| CNS PHARMACEUTICALS INC(CNSP) | 45,830 | 45,830 | 0 | 241 | 110 | 0.02% | -131 |
| GLUCOTRACK INC(GCTK) | 45,830 | 45,830 | 0 | 177 | 30 | 0.00% | -148 |
| PALISADE BIO INC(PALI) | 274,978 | 274,978 | 0 | 646 | 481 | 0.07% | -165 |
| SANGAMO THERAPEUTICS INC(SGMOQ) | 1,218,671 | 1,218,671 | 0 | 512 | 301 | 0.04% | -211 |
| BRIGHT MINDS BIOSCIENCES INC(DRUG) | 159,421 | 166,647 | +7,226 | 12,441 | 12,160 | 1.74% | -281 |
| STRUCTURE THERAPEUTICS INC | 4,824 | 0 | -4,824 | 336 | 0 | — | -336 |
| BRIDGEBIO ONCOLOGY THERAPEUT(BBOT) | 220,231 | 270,231 | +50,000 | 2,757 | 2,419 | 0.35% | -339 |
| DELCATH SYS INC(DCTH) | 431,251 | 431,251 | 0 | 4,356 | 4,002 | 0.57% | -354 |
| TARSUS PHARMACEUTICALS INC(TARS) | 31,166 | 31,166 | 0 | 2,552 | 2,186 | 0.31% | -366 |
| CONNECT BIOPHARMA HLDGS LTD(CNTB) | 4,788,486 | 5,388,486 | +600,000 | 13,504 | 13,118 | 1.88% | -386 |
| CUMBERLAND PHARMACEUTICALS I(CPIX) | 555,932 | 553,153 | -2,779 | 2,213 | 1,798 | 0.26% | -415 |
| LYELL IMMUNOPHARMA INC(LYEL) | 41,081 | 41,081 | 0 | 1,264 | 824 | 0.12% | -440 |
| CYBIN INC(HELP) | 132,153 | 132,153 | 0 | 1,081 | 634 | 0.09% | -447 |
| ARVINAS INC(ARVN) | 358,257 | 358,257 | 0 | 4,249 | 3,798 | 0.54% | -451 |
| PERCEPTIVE CAP SOLUTIONS COR CL A ORD SHS | 240,951 | 240,951 | 0 | 3,140 | 2,643 | 0.38% | -496 |