Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q1 2025 ▲▼ | Q2 2025 ▲▼ | Change ▲▼ | Q1 2025 ▲▼ | Q2 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| CIDARA THERAPEUTICS INC | 248,940 | 464,488 | +215,548 | 5,362 | 22,625 | 7.49% | +17,263 |
| APOGEE THERAPEUTICS INC(APGE) | 0 | 232,047 | +232,047 | 0 | 10,078 | 3.33% | +10,078 |
| INSMED INC(INSM) | 84,800 | 163,751 | +78,951 | 6,469 | 16,480 | 5.45% | +10,011 |
| ALNYLAM PHARMACEUTICALS INC(ALNY) | 31,594 | 56,594 | +25,000 | 8,531 | 18,455 | 6.11% | +9,924 |
| COGENT BIOSCIENCES INC(COGT) | 0 | 1,035,528 | +1,035,528 | 0 | 7,435 | 2.46% | +7,435 |
| PRAXIS PRECISION MEDICINES I(PRAX) | 145,502 | 276,950 | +131,448 | 5,510 | 11,646 | 3.85% | +6,136 |
| VERONA PHARMA PLC | 130,000 | 146,831 | +16,831 | 8,254 | 13,887 | 4.59% | +5,634 |
| ARVINAS INC(ARVN) | 229,900 | 850,000 | +620,100 | 1,614 | 6,256 | 2.07% | +4,642 |
| JAZZ PHARMACEUTICALS PLC(JAZZ) | 0 | 40,000 | +40,000 | 0 | 4,245 | 1.40% | +4,245 |
| CG ONCOLOGY INC(CGON) | 0 | 155,000 | +155,000 | 0 | 4,030 | 1.33% | +4,030 |
| NEWAMSTERDAM PHARMA COMPANY ORDINARY SHARES | 0 | 206,800 | +206,800 | 0 | 3,745 | 1.24% | +3,745 |
| ALPHA COGNITION INC(ACOG) | 967,867 | 917,867 | -50,000 | 5,110 | 8,564 | 2.83% | +3,453 |
| DELCATH SYS INC(DCTH) | 100,365 | 322,390 | +222,025 | 1,278 | 4,385 | 1.45% | +3,107 |
| BIOGEN INC(BIIB) | 0 | 21,516 | +21,516 | 0 | 2,702 | 0.89% | +2,702 |
| FULCRUM THERAPEUTICS INC(FULC) | 200,096 | 428,521 | +228,425 | 576 | 2,948 | 0.98% | +2,372 |
| VAXCYTE INC(PCVX) | 200,000 | 305,000 | +105,000 | 7,552 | 9,916 | 3.28% | +2,364 |
| KALVISTA PHARMACEUTICALS INC | 0 | 198,528 | +198,528 | 0 | 2,244 | 0.74% | +2,244 |
| GERON CORP(GERN) | 150,000 | 1,600,000 | +1,450,000 | 239 | 2,256 | 0.75% | +2,018 |
| AKERO THERAPEUTICS INC | 245,000 | 220,000 | -25,000 | 9,918 | 11,739 | 3.88% | +1,822 |
| PROQR THRAPEUTICS N V SHS EURO | 0 | 868,069 | +868,069 | 0 | 1,771 | 0.59% | +1,771 |
| CYTOKINETICS INC(CYTK) | 149,982 | 233,464 | +83,482 | 6,028 | 7,714 | 2.55% | +1,686 |
| UNIQURE NV(QURE) | 0 | 119,986 | +119,986 | 0 | 1,673 | 0.55% | +1,673 |
| VIKING THERAPEUTICS INC(VKTX) | 50,000 | 100,000 | +50,000 | 1,208 | 2,650 | 0.88% | +1,443 |
| FORTE BIOSCIENCES INC(FBRX) | 609,225 | 476,443 | -132,782 | 4,728 | 6,160 | 2.04% | +1,433 |
| SILENCE THERAPEUTICS PLC(SLN) | 0 | 873,568 | +873,568 | 0 | 1,398 | 0.46% | +1,398 |
| WAVE LIFE SCIENCES LTD(WVE) | 0 | 161,137 | +161,137 | 0 | 1,047 | 0.35% | +1,047 |
| ISHARES TR | 0 | 5,755 | +5,755 | 0 | 728 | 0.24% | +728 |
| VENTYX BIOSCIENCES INC | 1,217,590 | 967,590 | -250,000 | 1,400 | 2,071 | 0.69% | +670 |
| RELAY THERAPEUTICS INC(RLAY) | 743,308 | 743,308 | 0 | 1,947 | 2,572 | 0.85% | +624 |
| INFLARX NV(IFRX) | 0 | 705,010 | +705,010 | 0 | 557 | 0.18% | +557 |
| VYNE THERAPEUTICS INC(YARW) | 0 | 290,000 | +290,000 | 0 | 479 | 0.16% | +479 |
| ARCTURUS THERAPEUTICS HLDGS(ARCT) | 175,000 | 175,000 | 0 | 1,853 | 2,277 | 0.75% | +424 |
| KODIAK SCIENCES INC(KOD) | 649,534 | 599,534 | -50,000 | 1,822 | 2,236 | 0.74% | +414 |
| LYELL IMMUNOPHARMA INC(LYEL) | 0 | 43,799 | +43,799 | 0 | 387 | 0.13% | +387 |
| NYXOAH S A SHS | 0 | 50,627 | +50,627 | 0 | 379 | 0.13% | +379 |
| ANAPTYSBIO INC | 0 | 15,662 | +15,662 | 0 | 348 | 0.12% | +348 |
| VERA THERAPEUTICS INC(VERA) | 0 | 14,096 | +14,096 | 0 | 332 | 0.11% | +332 |
| ZYMEWORKS INC(ZYME) | 0 | 25,000 | +25,000 | 0 | 314 | 0.10% | +314 |
| LEXEO THERAPEUTICS INC(LXEO) | 550,029 | 550,029 | 0 | 1,909 | 2,211 | 0.73% | +303 |
| IMMATICS N.V(IMTX) | 0 | 49,396 | +49,396 | 0 | 266 | 0.09% | +266 |
| SENSEI BIOTHERAPEUTICS INC(FTH) | 0 | 22,497 | +22,497 | 0 | 193 | 0.06% | +193 |
| LYRA THERAPEUTICS INC | 0 | 21,161 | +21,161 | 0 | 190 | 0.06% | +190 |
| AETHLON MED INC | 0 | 153,659 | +153,659 | 0 | 184 | 0.06% | +184 |
| VERU INC(VERU) | 1,425,239 | 1,425,239 | 0 | 699 | 829 | 0.27% | +131 |
| NUVATION BIO INC(NUVB) | 619,258 | 619,258 | 0 | 1,090 | 1,208 | 0.40% | +118 |
| ALECTOR INC | 950,000 | 900,000 | -50,000 | 1,169 | 1,260 | 0.42% | +92 |
| AIRSCULPT TECHNOLOGIES INC | 0 | 17,951 | +17,951 | 0 | 87 | 0.03% | +87 |
| TOURMALINE BIO INC | 67,927 | 67,927 | 0 | 1,033 | 1,086 | 0.36% | +53 |
| SAGIMET BIOSCIENCES INC(SGMT) | 11,984 | 11,984 | 0 | 39 | 91 | 0.03% | +52 |
| EVAXION AS(EVAX) | 80,000 | 80,000 | 0 | 148 | 196 | 0.06% | +48 |
| ARCUS BIOSCIENCES INC(RCUS) | 163,363 | 163,363 | 0 | 1,282 | 1,330 | 0.44% | +47 |
| MIND MEDICINE MINDMED INC | 62,691 | 62,691 | 0 | 367 | 407 | 0.13% | +40 |
| JASPER THERAPEUTICS INC(JSPR) | 25,107 | 25,107 | 0 | 108 | 139 | 0.05% | +31 |
| ANEBULO PHARMACEUTICALS INC | 157,720 | 157,720 | 0 | 205 | 227 | 0.08% | +22 |
| ACUMEN PHARMACEUTICALS INC(ABOS) | 265,769 | 265,769 | 0 | 292 | 308 | 0.10% | +16 |
| KARYOPHARM THERAPEUTICS INC(KPTI) | 27,257 | 27,257 | 0 | 102 | 117 | 0.04% | +16 |
| CHEMOMAB THERAPEUTICS LTD | 213,052 | 213,052 | 0 | 232 | 247 | 0.08% | +15 |
| RELMADA THERAPEUTICS INC(RLMD) | 40,270 | 40,270 | 0 | 11 | 24 | 0.01% | +13 |
| INHIBRX BIOSCIENCES INC(INBX) | 42,122 | 42,122 | 0 | 589 | 601 | 0.20% | +12 |
| HOOKIPA PHARMA INC | 52,996 | 52,996 | 0 | 57 | 67 | 0.02% | +9 |
| SYNLOGIC INC(SYBX) | 20,422 | 20,422 | 0 | 25 | 26 | 0.01% | +1 |
| AUTONOMIX MED INC(AMIX) | 20,000 | 20,000 | 0 | 35 | 31 | 0.01% | -4 |
| ALPHA TEKNOVA INC(TKNO) | 14,008 | 14,008 | 0 | 73 | 69 | 0.02% | -4 |
| MACROGENICS INC(MGNX) | 80,071 | 80,071 | 0 | 102 | 97 | 0.03% | -5 |
| NEUMORA THERAPEUTICS INC.(NMRA) | 15,457 | 12,498 | -2,959 | 15 | 9 | 0.00% | -6 |
| VOYAGER THERAPEUTICS INC(VYGR) | 55,766 | 55,766 | 0 | 188 | 173 | 0.06% | -15 |
| TRAWS PHARMA INC(TRAW) | 28,493 | 28,493 | 0 | 66 | 42 | 0.01% | -23 |
| KEZAR LIFE SCIENCES INC COM NEW | 106,901 | 106,901 | 0 | 522 | 490 | 0.16% | -32 |
| PEPGEN INC(PEPG) | 150,000 | 150,000 | 0 | 211 | 167 | 0.06% | -44 |
| CARTESIAN THERAPEUTICS INC(RNAC) | 22,166 | 22,166 | 0 | 292 | 230 | 0.08% | -62 |
| THERIVA BIOLOGICS INC(TOVX) | 120,031 | 120,031 | 0 | 132 | 52 | 0.02% | -80 |
| BIOMX INC(PHGE) | 892,976 | 892,976 | 0 | 496 | 402 | 0.13% | -94 |
| VIRIDIAN THERAPEUTICS INC(VRDN) | 494,949 | 469,949 | -25,000 | 6,672 | 6,570 | 2.17% | -102 |
| LARIMAR THERAPEUTICS INC(LRMR) | 58,526 | 0 | -58,526 | 126 | 0 | — | -126 |
| LYRA THERAPEUTICS INC | 1,058,148 | 0 | -1,058,148 | 134 | 0 | — | -134 |
| ALTO NEUROSCIENCE INC(ANRO) | 175,000 | 110,000 | -65,000 | 378 | 242 | 0.08% | -136 |
| REZOLUTE INC(RZLT) | 50,058 | 0 | -50,058 | 145 | 0 | — | -145 |
| SENSEI BIOTHERAPEUTICS INC(FTH) | 449,963 | 0 | -449,963 | 177 | 0 | — | -177 |
| ELEVATION ONCOLOGY INC | 690,050 | 0 | -690,050 | 179 | 0 | — | -179 |
| VIGIL NEUROSCIENCE INC | 250,000 | 31,360 | -218,640 | 445 | 249 | 0.08% | -196 |
| NEURONETICS INC(STIM) | 1,100,000 | 1,099,700 | -300 | 4,048 | 3,838 | 1.27% | -210 |
| CLIMB BIO INC(CLYM) | 175,088 | 0 | -175,088 | 214 | 0 | — | -214 |
| MONOPAR THERAPEUTICS INC(MNPR) | 5,908 | 0 | -5,908 | 215 | 0 | — | -215 |
| SPRUCE BIOSCIENCES INC | 1,000,000 | 1,000,000 | 0 | 290 | 73 | 0.02% | -218 |
| ACLARIS THERAPEUTICS INC(ACRS) | 150,900 | 0 | -150,900 | 231 | 0 | — | -231 |
| ALLAKOS INC | 1,171,950 | 0 | -1,171,950 | 267 | 0 | — | -267 |
| DYNE THERAPEUTICS INC(DYN) | 358,837 | 363,837 | +5,000 | 3,753 | 3,464 | 1.15% | -290 |
| VISTAGEN THERAPEUTICS INC(VTGN) | 601,703 | 601,703 | 0 | 1,504 | 1,203 | 0.40% | -301 |
| TYRA BIOSCIENCES INC(TYRA) | 35,000 | 0 | -35,000 | 326 | 0 | — | -325 |
| MAZE THERAPEUTICS INC(MAZE) | 322,740 | 262,740 | -60,000 | 3,553 | 3,224 | 1.07% | -330 |
| GINKGO BIOWORKS HOLDINGS INC(DNA) | 58,300 | 0 | -58,300 | 332 | 0 | — | -332 |
| APELLIS PHARMACEUTICALS INC COM | 75,000 | 75,000 | 0 | 1,640 | 1,298 | 0.43% | -342 |
| THIRD HARMONIC BIO INC | 100,000 | 0 | -100,000 | 347 | 0 | — | -347 |
| IMMUNIC INC(IMUX) | 914,170 | 914,170 | 0 | 996 | 638 | 0.21% | -359 |
| AETHLON MED INC | 1,229,285 | 0 | -1,229,285 | 440 | 0 | — | -440 |
| ITEOS THERAPEUTICS INC | 78,585 | 0 | -78,585 | 469 | 0 | — | -469 |
| LYELL IMMUNOPHARMA INC(LYEL) | 876,037 | 0 | -876,037 | 471 | 0 | — | -471 |
| LEXICON PHARMACEUTICALS INC(LXRX) | 1,417,952 | 176,479 | -1,241,473 | 653 | 167 | 0.06% | -486 |
| JANUX THERAPEUTICS INC(JANX) | 129,691 | 129,691 | 0 | 3,502 | 2,996 | 0.99% | -506 |
| SANGAMO THERAPEUTICS INC(SGMOQ) | 1,860,179 | 1,260,179 | -600,000 | 1,220 | 682 | 0.23% | -538 |