Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Terns Pharmaceuticals Inc | 164,202 | 1,596,378 | +1,432,176 | $1.23M | $64.49M | 8.35% | +$63.26M |
| Cidara Therapeutics Inc | 277,704 | 273,243 | -4,461 | $26.59M | $60.36M | 7.81% | +$33.76M |
| ABIVAX Société AnonymeADS(ABVX) | 396,098 | 205,985 | -190,113 | $33.42M | $29.13M | 3.77% | -$4.29M |
| Jazz Pharmaceuticals plcSHS USD(JAZZ) | 77,800 | 160,367 | +82,567 | $10.25M | $27.26M | 3.53% | +$17.01M |
| Maze Therapeutics, Inc.(MAZE) | 740,825 | 644,680 | -96,145 | $19.21M | $26.71M | 3.46% | +$7.50M |
| Praxis Precision Medicines, Inc.(PRAX) | 28,571 | 86,581 | +58,010 | $1.51M | $25.52M | 3.30% | +$24.00M |
| Rapt Therapeutics Inc | 615,000 | 665,271 | +50,271 | $15.86M | $22.53M | 2.92% | +$6.67M |
| Kodiak Sciences Inc.(KOD) | 413,841 | 719,787 | +305,946 | $6.77M | $20.13M | 2.61% | +$13.35M |
| Olema Pharmaceuticals, Inc.(OLMA) | 0 | 758,654 | +758,654 | $0 | $18.97M | 2.45% | +$18.97M |
| Vaxcyte, Inc.(PCVX) | 311,682 | 378,682 | +67,000 | $11.23M | $17.47M | 2.26% | +$6.25M |
| Capricor Therapeutics, Inc.(CAPR) | 264,642 | 578,015 | +313,373 | $1.91M | $16.68M | 2.16% | +$14.77M |
| Ionis Pharmaceuticals, Inc.(IONS) | 415,163 | 202,038 | -213,125 | $27.16M | $15.98M | 2.07% | -$11.18M |
| Fulcrum Therapeutics, Inc.(FULC) | 1,289,225 | 1,375,472 | +86,247 | $11.86M | $15.56M | 2.01% | +$3.70M |
| Eli Lilly and Company(LLY) | 0 | 13,815 | +13,815 | $0 | $14.85M | 1.92% | +$14.85M |
| Relmada Therapeutics, Inc.(RLMD) | 1,843,060 | 3,068,359 | +1,225,299 | $3.70M | $14.82M | 1.92% | +$11.12M |
| Amgen Inc.(AMGN) | 0 | 45,000 | +45,000 | $0 | $14.73M | 1.91% | +$14.73M |
| CytomX Therapeutics, Inc.(CTMX) | 3,372,616 | 3,172,616 | -200,000 | $10.76M | $13.52M | 1.75% | +$2.76M |
| Pharvaris N V COM | 210,165 | 486,856 | +276,691 | $5.24M | $13.51M | 1.75% | +$8.27M |
| Connect Biopharma Holdings LimitedSHS(CNTB) | 0 | 4,788,486 | +4,788,486 | $0 | $13.50M | 1.75% | +$13.50M |
| Bright Minds Biosciences Inc.(DRUG) | 15,431 | 159,421 | +143,990 | $936.0K | $12.44M | 1.61% | +$11.51M |
| Tenax Therapeutics, Inc.(TENX) | 967,600 | 967,600 | 0 | $7.36M | $11.80M | 1.53% | +$4.43M |
| Revolution Medicines, Inc.(RVMD) | 0 | 138,142 | +138,142 | $0 | $11.00M | 1.42% | +$11.00M |
| Cytokinetics, Incorporated(CYTK) | 222,674 | 172,672 | -50,002 | $12.24M | $10.97M | 1.42% | -$1.27M |
| Spruce Biosciences Inc | 13,332 | 121,356 | +108,024 | $119.3K | $10.57M | 1.37% | +$10.45M |
| Celcuity Inc.(CELC) | 0 | 105,545 | +105,545 | $0 | $10.53M | 1.36% | +$10.53M |
| Alto Neuroscience, Inc.(ANRO) | 110,000 | 515,000 | +405,000 | $442.2K | $9.17M | 1.19% | +$8.72M |
| PTC Therapeutics, Inc.(PTCT) | 280,551 | 118,657 | -161,894 | $17.22M | $9.01M | 1.17% | -$8.20M |
| Harrow, Inc.(HROW) | 0 | 183,347 | +183,347 | $0 | $8.98M | 1.16% | +$8.98M |
| Ventyx Biosciences Inc | 1,309,604 | 958,704 | -350,900 | $4.07M | $8.66M | 1.12% | +$4.58M |
| CG Oncology, Inc.(CGON) | 249,473 | 199,473 | -50,000 | $10.05M | $8.28M | 1.07% | -$1.77M |
| Forte Biosciences Inc | 300,000 | 300,000 | 0 | $4.50M | $8.18M | 1.06% | +$3.68M |
| Pelthos Therapeutics Inc.(PTHS) | 62,451 | 255,758 | +193,307 | $1.75M | $7.93M | 1.03% | +$6.18M |
| Neurocrine Biosciences, Inc.(NBIX) | 0 | 54,062 | +54,062 | $0 | $7.67M | 0.99% | +$7.67M |
| Mineralys Therapeutics, Inc.(MLYS) | 0 | 200,000 | +200,000 | $0 | $7.26M | 0.94% | +$7.26M |
| Alpha Cognition Inc. Common Stock(ACOG) | 946,259 | 1,056,259 | +110,000 | $6.16M | $6.87M | 0.89% | +$705.5K |
| Damora Therapeutics, Inc.(DMRA) | 0 | 285,710 | +285,710 | $0 | $6.57M | 0.85% | +$6.57M |
| Invivyd, Inc.(IVVD) | 2,078,706 | 2,656,570 | +577,864 | $2.29M | $6.56M | 0.85% | +$4.28M |
| Corcept Therapeutics Incorporated(CORT) | 0 | 185,593 | +185,593 | $0 | $6.46M | 0.84% | +$6.46M |
| Nuvalent Inc | 0 | 59,594 | +59,594 | $0 | $5.99M | 0.78% | +$5.99M |
| Lexeo Therapeutics, Inc.(LXEO) | 567,601 | 513,011 | -54,590 | $3.77M | $5.09M | 0.66% | +$1.33M |
| Legend Biotech CorporationADS(LEGN) | 0 | 226,888 | +226,888 | $0 | $4.93M | 0.64% | +$4.93M |
| Jade Biosciences Inc | 0 | 300,000 | +300,000 | $0 | $4.63M | 0.60% | +$4.63M |
| Eupraxia Pharmaceuticals Inc.(EPRX) | 0 | 610,000 | +610,000 | $0 | $4.61M | 0.60% | +$4.61M |
| Delcath Systems, Inc.(DCTH) | 431,251 | 431,251 | 0 | $4.64M | $4.36M | 0.56% | -$280.3K |
| Compass Therapeutics, Inc.(CMPX) | 0 | 800,000 | +800,000 | $0 | $4.30M | 0.56% | +$4.30M |
| Adma Biologics Inc | 159,854 | 234,854 | +75,000 | $2.34M | $4.28M | 0.55% | +$1.94M |
| Arvinas, Inc.(ARVN) | 226,257 | 358,257 | +132,000 | $1.93M | $4.25M | 0.55% | +$2.32M |
| Zura Bio LimitedCL A(ZURA) | 2,132,322 | 802,322 | -1,330,000 | $9.23M | $4.20M | 0.54% | -$5.03M |
| Karyopharm Therapeutics Inc.(KPTI) | 27,257 | 544,554 | +517,297 | $178.3K | $4.01M | 0.52% | +$3.83M |
| Krystal Biotech, Inc.(KRYS) | 24,421 | 14,814 | -9,607 | $4.31M | $3.65M | 0.47% | -$658.8K |
| TG Therapeutics, Inc.(TGTX) | 174,959 | 117,903 | -57,056 | $6.32M | $3.51M | 0.45% | -$2.81M |
| Vir Biotechnology, Inc.(VIR) | 593,374 | 575,712 | -17,662 | $3.39M | $3.47M | 0.45% | +$83.4K |
| Nextcure Inc | 0 | 238,303 | +238,303 | $0 | $3.38M | 0.44% | +$3.38M |
| Alector Inc | 760,000 | 2,082,606 | +1,322,606 | $2.25M | $3.25M | 0.42% | +$999.3K |
| Contineum Therapeutics, Inc.CL A(CTNM) | 0 | 282,874 | +282,874 | $0 | $3.23M | 0.42% | +$3.23M |
| Soleno Therapeutics Inc | 55,946 | 68,823 | +12,877 | $3.78M | $3.19M | 0.41% | -$595.4K |
| Agios Pharmaceuticals, Inc.(AGIO) | 126,979 | 115,489 | -11,490 | $5.10M | $3.14M | 0.41% | -$1.95M |
| Perceptive Cap Solutions CorCL A CL A ORD SHS | 0 | 240,951 | +240,951 | $0 | $3.14M | 0.41% | +$3.14M |
| Quoin Pharmaceuticals, Ltd.ADS(QNRX) | 0 | 211,538 | +211,538 | $0 | $3.05M | 0.40% | +$3.05M |
| Kalaris Therapeutics, Inc.(KLRS) | 0 | 360,000 | +360,000 | $0 | $3.04M | 0.39% | +$3.04M |
| Proqr Thrapeutics N VSHS EURO SHS EURO | 892,229 | 1,492,229 | +600,000 | $1.90M | $3.01M | 0.39% | +$1.11M |
| PepGen Inc.(PEPG) | 535,967 | 447,165 | -88,802 | $2.48M | $2.91M | 0.38% | +$434.9K |
| COMPASS Pathways plcADS(CMPS) | 0 | 400,000 | +400,000 | $0 | $2.76M | 0.36% | +$2.76M |
| BridgeBio Oncology Therapeutics, Inc.(BBOT) | 245,231 | 220,231 | -25,000 | $2.84M | $2.76M | 0.36% | -$82.5K |
| Erasca, Inc.(ERAS) | 0 | 735,396 | +735,396 | $0 | $2.74M | 0.35% | +$2.74M |
| Tarsus Pharmaceuticals, Inc.(TARS) | 73,619 | 31,166 | -42,453 | $4.38M | $2.55M | 0.33% | -$1.82M |
| Fractyl Health, Inc.(GUTS) | 1,800,000 | 1,100,000 | -700,000 | $2.86M | $2.42M | 0.31% | -$442.0K |
| Biohaven Ltd.(BHVN) | 0 | 212,481 | +212,481 | $0 | $2.40M | 0.31% | +$2.40M |
| Inventiva S.A.ADS(IVA) | 0 | 502,601 | +502,601 | $0 | $2.33M | 0.30% | +$2.33M |
| Neumora Therapeutics, Inc.(NMRA) | 12,498 | 1,278,408 | +1,265,910 | $22.7K | $2.29M | 0.30% | +$2.27M |
| Cumberland Pharmaceuticals Inc.(CPIX) | 555,932 | 555,932 | 0 | $1.73M | $2.21M | 0.29% | +$478.1K |
| uniQure N.V.SHS(QURE) | 58,610 | 91,060 | +32,450 | $3.42M | $2.18M | 0.28% | -$1.24M |
| DBV Technologies S.A.ADS(DBVT) | 0 | 525,000 | +525,000 | $0 | $2.08M | 0.27% | +$2.08M |
| Cabaletta Bio, Inc.(CABA) | 0 | 900,000 | +900,000 | $0 | $1.97M | 0.26% | +$1.97M |
| Journey Medical Corporation(DERM) | 0 | 251,436 | +251,436 | $0 | $1.94M | 0.25% | +$1.94M |
| iBio, Inc.(IBIO) | 617,327 | 957,062 | +339,735 | $511.0K | $1.85M | 0.24% | +$1.34M |
| Apellis Pharmaceuticals Inc COM | 451,902 | 71,747 | -380,155 | $10.23M | $1.80M | 0.23% | -$8.42M |
| Silence Therapeutics plcADS(SLN) | 900,784 | 865,784 | -35,000 | $1.31M | $1.73M | 0.22% | +$425.4K |
| Verastem, Inc.(VSTM) | 0 | 213,865 | +213,865 | $0 | $1.65M | 0.21% | +$1.65M |
| Insmed Incorporated(INSM) | 13,751 | 9,337 | -4,414 | $1.98M | $1.63M | 0.21% | -$355.3K |
| Newamsterdam Pharma Company ORDINARY SHARES | 106,800 | 45,830 | -60,970 | $3.04M | $1.61M | 0.21% | -$1.43M |
| Lipocine Inc.(LPCN) | 0 | 199,542 | +199,542 | $0 | $1.60M | 0.21% | +$1.60M |
| Surrozen, Inc.(SRZN) | 0 | 65,788 | +65,788 | $0 | $1.49M | 0.19% | +$1.49M |
| Wave Life Sciences, Inc.SHS(WVE) | 95,955 | 85,285 | -10,670 | $702.4K | $1.45M | 0.19% | +$747.5K |
| Catalyst Pharmaceuticals Inc | 116,388 | 57,388 | -59,000 | $2.29M | $1.34M | 0.17% | -$953.4K |
| Lyell Immunopharma, Inc.(LYEL) | 43,799 | 41,081 | -2,718 | $711.3K | $1.26M | 0.16% | +$553.2K |
| Annexon, Inc.(ANNX) | 0 | 230,244 | +230,244 | $0 | $1.16M | 0.15% | +$1.16M |
| Cybin D/B/A Helus Pharma(HELP) | 140,475 | 132,153 | -8,322 | $827.4K | $1.08M | 0.14% | +$253.6K |
| Neuronetics, Inc.(STIM) | 905,716 | 701,182 | -204,534 | $2.47M | $967.6K | 0.13% | -$1.50M |
| Solid Biosciences Inc | 176,690 | 160,409 | -16,281 | $1.09M | $904.7K | 0.12% | -$185.5K |
| Direxion Shs Etf TrDAILY S P BIOTEC DAI BIO BEA ETF | 91,959 | 40,822 | -51,137 | $3.72M | $859.7K | 0.11% | -$2.86M |
| Io Biotech Inc | 1,525,893 | 1,386,565 | -139,328 | $554.1K | $844.3K | 0.11% | +$290.2K |
| Mind Medicine Mindmed Inc | 62,691 | 58,803 | -3,888 | $739.1K | $787.4K | 0.10% | +$48.2K |
| Traws Pharma, Inc.(TRAW) | 28,493 | 678,142 | +649,649 | $52.7K | $766.3K | 0.10% | +$713.6K |
| Palisade Bio, Inc.(PALI) | 0 | 274,978 | +274,978 | $0 | $646.2K | 0.08% | +$646.2K |
| Kezar Life Sciences Inc COM NEW | 106,901 | 102,211 | -4,690 | $416.9K | $642.9K | 0.08% | +$226.0K |
| Kalvista Pharmaceuticals Inc | 0 | 35,119 | +35,119 | $0 | $567.2K | 0.07% | +$567.2K |
| Avalo Therapeutics, Inc.(AVTX) | 159,777 | 31,106 | -128,671 | $2.03M | $564.9K | 0.07% | -$1.47M |
| Acumen Pharmaceuticals, Inc.(ABOS) | 265,769 | 254,312 | -11,457 | $454.5K | $536.6K | 0.07% | +$82.1K |
| Sangamo Therapeutics, Inc.(SGMOQ) | 1,294,652 | 1,218,671 | -75,981 | $871.8K | $511.8K | 0.07% | -$360.0K |