Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2023 ▲▼ | Q1 2024 ▲▼ | Change ▲▼ | Q4 2023 ▲▼ | Q1 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Fusion Pharmaceuticals Inc | 6,500,328 | 6,500,328 | 0 | $62.47M | $138.59M | 4.93% | +$76.12M |
| Boston Scientific Corporation(BSX) | 1,890,000 | 1,956,000 | +66,000 | $109.26M | $133.97M | 4.76% | +$24.71M |
| Arvinas, Inc.(ARVN) | 2,985,117 | 2,985,190 | +73 | $122.87M | $123.23M | 4.38% | +$361.2K |
| Intuitive Surgical, Inc.(ISRG) | 85,000 | 226,000 | +141,000 | $28.68M | $90.19M | 3.21% | +$61.52M |
| Dianthus Therapeutics, Inc.(DNTH) | 1,217,554 | 2,717,554 | +1,500,000 | $12.66M | $81.53M | 2.90% | +$68.86M |
| Acadia Healthcare Company, Inc.(ACHC) | 1,156,692 | 1,005,000 | -151,692 | $89.94M | $79.62M | 2.83% | -$10.33M |
| Neurocrine Biosciences, Inc.(NBIX) | 658,000 | 536,500 | -121,500 | $86.70M | $73.99M | 2.63% | -$12.70M |
| Natera, Inc.(NTRA) | 1,110,000 | 803,300 | -306,700 | $69.53M | $73.47M | 2.61% | +$3.94M |
| Jazz Pharmaceuticals plcSHS USD(JAZZ) | 489,119 | 584,000 | +94,881 | $60.16M | $70.33M | 2.50% | +$10.16M |
| Avantor, Inc.(AVTR) | 2,121,844 | 2,695,000 | +573,156 | $48.44M | $68.91M | 2.45% | +$20.47M |
| The Cigna Group(CI) | 0 | 184,500 | +184,500 | $0 | $67.01M | 2.38% | +$67.01M |
| Merck & Co., Inc.(MRK) | 0 | 502,000 | +502,000 | $0 | $66.24M | 2.35% | +$66.24M |
| Regeneron Pharmaceuticals, Inc.(REGN) | 68,000 | 68,000 | 0 | $59.72M | $65.45M | 2.33% | +$5.73M |
| CG Oncology, Inc.(CGON) | 0 | 1,454,765 | +1,454,765 | $0 | $63.86M | 2.27% | +$63.86M |
| Illumina, Inc.(ILMN) | 0 | 464,100 | +464,100 | $0 | $63.73M | 2.27% | +$63.73M |
| Tenet Healthcare Corporation(THC) | 871,000 | 601,000 | -270,000 | $65.82M | $63.17M | 2.25% | -$2.65M |
| Align Technology Inc | 155,800 | 189,000 | +33,200 | $42.69M | $61.98M | 2.20% | +$19.29M |
| Syndax Pharmaceuticals, Inc.(SNDX) | 3,950,000 | 2,412,500 | -1,537,500 | $85.36M | $57.42M | 2.04% | -$27.94M |
| Eli Lilly and Company(LLY) | 85,000 | 70,000 | -15,000 | $49.55M | $54.46M | 1.94% | +$4.91M |
| United Therapeutics Corporation(UTHR) | 237,202 | 217,000 | -20,202 | $52.16M | $49.85M | 1.77% | -$2.31M |
| Alpine Immune Sciences Inc | 0 | 1,174,700 | +1,174,700 | $0 | $46.57M | 1.66% | +$46.57M |
| Ultragenyx Pharmaceutical Inc.(RARE) | 844,500 | 933,500 | +89,000 | $40.38M | $43.59M | 1.55% | +$3.20M |
| CVS Health Corporation(CVS) | 740,000 | 545,000 | -195,000 | $58.43M | $43.47M | 1.55% | -$14.96M |
| Surgery Partners, Inc.(SGRY) | 1,165,932 | 1,445,000 | +279,068 | $37.30M | $43.10M | 1.53% | +$5.81M |
| Intra-Cellular Therapies Inc | 710,000 | 600,000 | -110,000 | $50.85M | $41.52M | 1.48% | -$9.33M |
| AbbVie Inc.(ABBV) | 284,405 | 227,000 | -57,405 | $44.07M | $41.34M | 1.47% | -$2.74M |
| Blueprint Medicines Corp | 615,000 | 426,000 | -189,000 | $56.73M | $40.41M | 1.44% | -$16.32M |
| Legend Biotech CorporationADS(LEGN) | 685,000 | 668,300 | -16,700 | $41.22M | $37.48M | 1.33% | -$3.73M |
| Structure Therapeutics IncADS | 1,080,000 | 864,000 | -216,000 | $44.02M | $37.03M | 1.32% | -$6.99M |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 0 | 243,000 | +243,000 | $0 | $36.32M | 1.29% | +$36.32M |
| Danaher Corporation(DHR) | 290,000 | 143,800 | -146,200 | $67.09M | $35.91M | 1.28% | -$31.18M |
| IDEAYA Biosciences, Inc.(IDYA) | 1,520,000 | 799,700 | -720,300 | $54.08M | $35.09M | 1.25% | -$18.99M |
| Axsome Therapeutics, Inc.(AXSM) | 459,400 | 431,000 | -28,400 | $36.56M | $34.39M | 1.22% | -$2.17M |
| Xenon Pharmaceuticals Inc.(XENE) | 815,993 | 710,000 | -105,993 | $37.58M | $30.57M | 1.09% | -$7.02M |
| Lantheus Holdings, Inc.(LNTH) | 380,000 | 480,000 | +100,000 | $23.56M | $29.88M | 1.06% | +$6.32M |
| Caribou Biosciences, Inc.(CRBU) | 6,360,212 | 5,785,352 | -574,860 | $36.44M | $29.74M | 1.06% | -$6.71M |
| Mirum Pharmaceuticals, Inc.(MIRM) | 1,142,850 | 1,142,850 | 0 | $33.74M | $28.71M | 1.02% | -$5.03M |
| Rocket Pharmaceuticals, Inc.(RCKT) | 1,719,103 | 1,025,000 | -694,103 | $51.52M | $27.61M | 0.98% | -$23.91M |
| REGENXBIO Inc.(RGNX) | 0 | 1,300,064 | +1,300,064 | $0 | $27.39M | 0.97% | +$27.39M |
| Apogee Therapeutics Inc | 0 | 384,893 | +384,893 | $0 | $25.58M | 0.91% | +$25.58M |
| Neumora Therapeutics, Inc.(NMRA) | 1,990,632 | 1,800,000 | -190,632 | $33.94M | $24.75M | 0.88% | -$9.19M |
| DexCom, Inc.(DXCM) | 0 | 176,900 | +176,900 | $0 | $24.54M | 0.87% | +$24.54M |
| Neurogene Inc.(NGNE) | 466,243 | 465,237 | -1,006 | $9.04M | $23.68M | 0.84% | +$14.64M |
| Jasper Therapeutics, Inc.(JSPR) | 0 | 760,000 | +760,000 | $0 | $22.31M | 0.79% | +$22.31M |
| Immunome, Inc.(IMNM) | 1,333,479 | 873,891 | -459,588 | $14.27M | $21.57M | 0.77% | +$7.30M |
| Thermo Fisher Scientific Inc.(TMO) | 182,600 | 36,600 | -146,000 | $96.92M | $21.27M | 0.76% | -$75.65M |
| Glaukos Corporation(GKOS) | 0 | 224,000 | +224,000 | $0 | $21.12M | 0.75% | +$21.12M |
| Revolution Medicines, Inc.(RVMD) | 60,000 | 635,000 | +575,000 | $1.72M | $20.47M | 0.73% | +$18.75M |
| Vaxcyte, Inc.(PCVX) | 570,137 | 284,000 | -286,137 | $35.80M | $19.40M | 0.69% | -$16.40M |
| Immunocore Holdings plcADS(IMCR) | 300,200 | 286,400 | -13,800 | $20.51M | $18.62M | 0.66% | -$1.89M |
| Phathom Pharmaceuticals, Inc.(PHAT) | 1,721,580 | 1,735,000 | +13,420 | $15.72M | $18.43M | 0.65% | +$2.71M |
| McKesson Corporation(MCK) | 85,500 | 33,300 | -52,200 | $39.58M | $17.88M | 0.64% | -$21.71M |
| Vera Therapeutics, Inc.CL A(VERA) | 0 | 383,500 | +383,500 | $0 | $16.54M | 0.59% | +$16.54M |
| Immunovant, Inc.(IMVT) | 245,000 | 505,000 | +260,000 | $10.32M | $16.32M | 0.58% | +$5.99M |
| Privia Health Group, Inc.(PRVA) | 1,287,000 | 764,200 | -522,800 | $29.64M | $14.97M | 0.53% | -$14.67M |
| Janux Therapeutics, Inc.(JANX) | 0 | 384,245 | +384,245 | $0 | $14.47M | 0.51% | +$14.47M |
| Cybin D/B/A Helus Pharma(HELP) | 0 | 34,884,000 | +34,884,000 | $0 | $14.42M | 0.51% | +$14.42M |
| Collegium Pharmaceutical, Inc.(COLL) | 361,363 | 361,400 | +37 | $11.12M | $14.03M | 0.50% | +$2.91M |
| Prime Medicine, Inc.(PRME) | 0 | 1,990,000 | +1,990,000 | $0 | $13.93M | 0.50% | +$13.93M |
| Keros Therapeutics, Inc.(KROS) | 0 | 209,700 | +209,700 | $0 | $13.88M | 0.49% | +$13.88M |
| Astria Therapeutics Inc | 0 | 982,000 | +982,000 | $0 | $13.82M | 0.49% | +$13.82M |
| AC Immune SASHS(ACIU) | 4,469,080 | 4,470,000 | +920 | $22.35M | $13.23M | 0.47% | -$9.11M |
| Karyopharm Therapeutics Inc.(KPTI) | 8,298,570 | 8,298,570 | 0 | $7.18M | $12.53M | 0.45% | +$5.35M |
| Immunic, Inc.(IMUX) | 0 | 8,902,972 | +8,902,972 | $0 | $11.75M | 0.42% | +$11.75M |
| Cytokinetics, Incorporated(CYTK) | 0 | 166,000 | +166,000 | $0 | $11.64M | 0.41% | +$11.64M |
| RadNet, Inc.(RDNT) | 0 | 238,000 | +238,000 | $0 | $11.58M | 0.41% | +$11.58M |
| Establishment Labs Holdings Inc.(ESTA) | 0 | 225,000 | +225,000 | $0 | $11.45M | 0.41% | +$11.45M |
| Newamsterdam Pharma Company ORDINARY SHARES | 0 | 475,000 | +475,000 | $0 | $11.23M | 0.40% | +$11.23M |
| Acadia Pharmaceuticals Inc | 0 | 588,500 | +588,500 | $0 | $10.88M | 0.39% | +$10.88M |
| AstraZeneca PLCADR(AZN) | 0 | 160,000 | +160,000 | $0 | $10.84M | 0.39% | +$10.84M |
| Syros Pharmaceuticals Inc | 1,673,538 | 1,673,538 | 0 | $13.04M | $8.95M | 0.32% | -$4.08M |
| Ionis Pharmaceuticals, Inc.(IONS) | 0 | 130,000 | +130,000 | $0 | $5.64M | 0.20% | +$5.64M |
| Century Therapeutics, Inc.(IPSC) | 1,355,000 | 1,221,555 | -133,445 | $4.50M | $5.11M | 0.18% | +$607.5K |
| Kyverna Therapeutics, Inc.(KYTX) | 0 | 202,333 | +202,333 | $0 | $5.03M | 0.18% | +$5.03M |
| Emergent BioSolutions Inc.(EBS) | 0 | 1,908,000 | +1,908,000 | $0 | $4.83M | 0.17% | +$4.83M |
| Kezar Life Sciences Inc | 5,025,454 | 5,026,000 | +546 | $4.76M | $4.53M | 0.16% | -$229.7K |
| Biohaven Ltd.(BHVN) | 1,148,308 | 75,000 | -1,073,308 | $49.15M | $4.10M | 0.15% | -$45.05M |
| An2 Therapeutics Inc | 1,140,000 | 1,150,000 | +10,000 | $23.36M | $3.74M | 0.13% | -$19.62M |
| Ginkgo Bioworks Holdings, Inc.CL A(DNA) | 0 | 3,000,000 | +3,000,000 | $0 | $3.48M | 0.12% | +$3.48M |
| X4 Pharmaceuticals, Inc.(XFOR) | 0 | 2,413,000 | +2,413,000 | $0 | $3.35M | 0.12% | +$3.35M |
| Cogent Biosciences, Inc.(COGT) | 0 | 445,706 | +445,706 | $0 | $3.00M | 0.11% | +$3.00M |
| Pacific Biosciences of California, Inc.(PACB) | 0 | 675,000 | +675,000 | $0 | $2.53M | 0.09% | +$2.53M |
| SCYNEXIS, Inc.(SCYX) | 1,448,728 | 1,448,728 | 0 | $3.23M | $2.13M | 0.08% | -$1.10M |
| Kodiak Sciences Inc.(KOD) | 0 | 300,000 | +300,000 | $0 | $1.58M | 0.06% | +$1.58M |
| Hyperfine, Inc.CL A(HYPR) | 1,188,178 | 1,188,178 | 0 | $1.33M | $1.19M | 0.04% | -$142.6K |
| Caremax IncCL A | 0 | 21,200 | +21,200 | $0 | $102.2K | 0.00% | +$102.2K |
| Nuvation Bio Inc.W EXP 07 07 202(NUVB) | 89,543 | 89,543 | 0 | $5.4K | $27.1K | 0.00% | +$21.7K |
| Agilent Technologies, Inc.(A) | 99,000 | 0 | -99,000 | $13.76M | $0 | — | -$13.76M |
| Akero Therapeutics Inc | 235,000 | 0 | -235,000 | $5.49M | $0 | — | -$5.49M |
| Amylyx Pharmaceuticals, Inc.(AMLX) | 64,501 | 0 | -64,501 | $949.5K | $0 | — | -$949.5K |
| argenx SEADR(ARGX) | 31,000 | 0 | -31,000 | $11.79M | $0 | — | -$11.79M |
| Arrowhead Pharmaceuticals, Inc.(ARWR) | 714,000 | 0 | -714,000 | $21.85M | $0 | — | -$21.85M |
| Becton, Dickinson and Company(BDX) | 165,706 | 0 | -165,706 | $40.40M | $0 | — | -$40.40M |
| Caremax IncCL A | 636,000 | 0 | -636,000 | $316.9K | $0 | — | -$316.9K |
| Cerevel Therapeutics Hldng I | 276,888 | 0 | -276,888 | $11.74M | $0 | — | -$11.74M |
| Compass Therapeutics, Inc.(CMPX) | 1,599,600 | 0 | -1,599,600 | $2.50M | $0 | — | -$2.50M |
| Crinetics Pharmaceuticals In | 529,000 | 0 | -529,000 | $18.82M | $0 | — | -$18.82M |
| Humana Inc.(HUM) | 100,000 | 0 | -100,000 | $45.78M | $0 | — | -$45.78M |
| Immunogen Inc | 1,829,215 | 0 | -1,829,215 | $54.24M | $0 | — | -$54.24M |
| Intellia Therapeutics, Inc.(NTLA) | 447,434 | 0 | -447,434 | $13.64M | $0 | — | -$13.64M |