Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2024 ▲▼ | Q4 2024 ▲▼ | Change ▲▼ | Q3 2024 ▲▼ | Q4 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Dianthus Therapeutics, Inc.(DNTH) | 2,917,231 | 2,873,000 | -44,231 | $79.87M | $62.63M | 6.24% | -$17.24M |
| Boston Scientific Corporation(BSX) | 962,000 | 515,000 | -447,000 | $80.62M | $46.00M | 4.59% | -$34.62M |
| Janux Therapeutics, Inc.(JANX) | 562,000 | 741,900 | +179,900 | $25.53M | $39.72M | 3.96% | +$14.19M |
| Natera, Inc.(NTRA) | 556,400 | 223,800 | -332,600 | $70.63M | $35.43M | 3.53% | -$35.21M |
| Endeavour Silver Corp.(EXK) | 588,000 | 603,011 | +15,011 | $40.05M | $33.88M | 3.38% | -$6.17M |
| Intuitive Surgical, Inc.(ISRG) | 148,200 | 64,800 | -83,400 | $72.81M | $33.82M | 3.37% | -$38.98M |
| CG Oncology, Inc.(CGON) | 1,656,000 | 1,097,800 | -558,200 | $62.48M | $31.48M | 3.14% | -$31.00M |
| UnitedHealth Group Incorporated(UNH) | 87,400 | 60,000 | -27,400 | $51.10M | $30.35M | 3.03% | -$20.75M |
| Neurocrine Biosciences, Inc.(NBIX) | 460,000 | 220,400 | -239,600 | $53.00M | $30.08M | 3.00% | -$22.92M |
| IDEAYA Biosciences, Inc.(IDYA) | 1,373,000 | 1,126,700 | -246,300 | $43.50M | $28.96M | 2.89% | -$14.54M |
| Jazz Pharmaceuticals plcSHS USD(JAZZ) | 431,000 | 234,500 | -196,500 | $48.02M | $28.88M | 2.88% | -$19.14M |
| Mirum Pharmaceuticals, Inc.(MIRM) | 731,104 | 666,200 | -64,904 | $28.51M | $27.55M | 2.75% | -$965.7K |
| Acadia Healthcare Company, Inc.(ACHC) | 985,000 | 658,000 | -327,000 | $62.46M | $26.09M | 2.60% | -$36.37M |
| Arvinas, Inc.(ARVN) | 1,497,000 | 1,358,000 | -139,000 | $36.87M | $26.03M | 2.60% | -$10.84M |
| Glaukos Corporation(GKOS) | 344,900 | 170,000 | -174,900 | $44.93M | $25.49M | 2.54% | -$19.44M |
| DexCom, Inc.(DXCM) | 240,000 | 318,000 | +78,000 | $16.09M | $24.73M | 2.47% | +$8.64M |
| Thermo Fisher Scientific Inc.(TMO) | 68,600 | 44,600 | -24,000 | $42.43M | $23.20M | 2.31% | -$19.23M |
| Humana Inc.(HUM) | 129,700 | 89,200 | -40,500 | $41.08M | $22.63M | 2.26% | -$18.45M |
| Kymera Therapeutics, Inc.(KYMR) | 500,000 | 500,000 | 0 | $23.66M | $20.11M | 2.01% | -$3.55M |
| Avantor, Inc.(AVTR) | 1,235,000 | 947,000 | -288,000 | $31.95M | $19.95M | 1.99% | -$12.00M |
| Syndax Pharmaceuticals, Inc.(SNDX) | 2,455,000 | 1,500,000 | -955,000 | $47.26M | $19.83M | 1.98% | -$27.43M |
| Centessa Pharmaceuticals PlcADS | 2,132,000 | 1,165,800 | -966,200 | $34.09M | $19.53M | 1.95% | -$14.56M |
| Revolution Medicines, Inc.(RVMD) | 790,000 | 446,200 | -343,800 | $35.83M | $19.52M | 1.95% | -$16.31M |
| Xenon Pharmaceuticals Inc.(XENE) | 818,000 | 474,000 | -344,000 | $32.20M | $18.58M | 1.85% | -$13.62M |
| Tenet Healthcare Corporation(THC) | 253,000 | 137,000 | -116,000 | $42.05M | $17.29M | 1.72% | -$24.76M |
| Insmed Incorporated(INSM) | 592,000 | 232,800 | -359,200 | $43.22M | $16.07M | 1.60% | -$27.14M |
| Axsome Therapeutics, Inc.(AXSM) | 296,100 | 188,000 | -108,100 | $26.61M | $15.91M | 1.59% | -$10.70M |
| Blueprint Medicines Corp | 315,000 | 176,600 | -138,400 | $29.14M | $15.40M | 1.54% | -$13.73M |
| Danaher Corporation(DHR) | 95,000 | 67,000 | -28,000 | $26.41M | $15.38M | 1.53% | -$11.03M |
| Ultragenyx Pharmaceutical Inc.(RARE) | 752,000 | 352,000 | -400,000 | $41.77M | $14.81M | 1.48% | -$26.96M |
| Illumina, Inc.(ILMN) | 292,000 | 109,700 | -182,300 | $38.08M | $14.66M | 1.46% | -$23.42M |
| AbbVie Inc.(ABBV) | 100,000 | 80,700 | -19,300 | $19.75M | $14.34M | 1.43% | -$5.41M |
| Rocket Pharmaceuticals, Inc.(RCKT) | 749,000 | 1,053,300 | +304,300 | $13.83M | $13.24M | 1.32% | -$594.0K |
| Bristol-Myers Squibb Company(BMY) | 263,000 | 215,000 | -48,000 | $13.61M | $12.16M | 1.21% | -$1.45M |
| TransMedics Group, Inc.(TMDX) | 27,600 | 192,400 | +164,800 | $4.33M | $12.00M | 1.20% | +$7.66M |
| Phathom Pharmaceuticals, Inc.(PHAT) | 1,804,493 | 1,390,100 | -414,393 | $32.63M | $11.29M | 1.13% | -$21.34M |
| Surgery Partners, Inc.(SGRY) | 827,000 | 514,200 | -312,800 | $26.66M | $10.89M | 1.09% | -$15.78M |
| ORIC Pharmaceuticals, Inc.(ORIC) | 1,447,119 | 1,265,200 | -181,919 | $14.83M | $10.21M | 1.02% | -$4.62M |
| Newamsterdam Pharma Company ORDINARY SHARES | 889,700 | 354,000 | -535,700 | $14.77M | $9.10M | 0.91% | -$5.67M |
| Incyte Corporation(INCY) | 308,110 | 129,600 | -178,510 | $20.37M | $8.95M | 0.89% | -$11.41M |
| Perspective Therapeutics, Inc.(CATX) | 3,444,002 | 2,694,600 | -749,402 | $45.98M | $8.60M | 0.86% | -$37.38M |
| Ascendis Pharma A/SADR(ASND) | 119,000 | 62,000 | -57,000 | $17.77M | $8.54M | 0.85% | -$9.23M |
| Biohaven Ltd.(BHVN) | 465,000 | 222,900 | -242,100 | $23.24M | $8.33M | 0.83% | -$14.91M |
| Intra-Cellular Therapies Inc | 233,000 | 97,000 | -136,000 | $17.05M | $8.10M | 0.81% | -$8.95M |
| Immunic, Inc.(IMUX) | 8,266,000 | 7,966,400 | -299,600 | $13.64M | $7.97M | 0.79% | -$5.67M |
| Context Therapeutics Inc.(CNTX) | 7,417,155 | 7,477,200 | +60,045 | $14.54M | $7.85M | 0.78% | -$6.69M |
| Oruka Therapeutics, Inc.(ORKA) | 790,926 | 352,124 | -438,802 | $19.39M | $6.83M | 0.68% | -$12.56M |
| Regeneron Pharmaceuticals, Inc.(REGN) | 0 | 8,400 | +8,400 | $0 | $5.98M | 0.60% | +$5.98M |
| Bruker Corporation(BRKR) | 0 | 76,300 | +76,300 | $0 | $4.47M | 0.45% | +$4.47M |
| Vera Therapeutics, Inc.CL A(VERA) | 0 | 100,000 | +100,000 | $0 | $4.23M | 0.42% | +$4.23M |
| REGENXBIO Inc.(RGNX) | 1,132,564 | 532,000 | -600,564 | $11.88M | $4.11M | 0.41% | -$7.77M |
| uniQure N.V.SHS(QURE) | 673,618 | 222,000 | -451,618 | $3.32M | $3.92M | 0.39% | +$599.6K |
| Kezar Life Sciences Inc COM NEW | 0 | 502,600 | +502,600 | $0 | $3.38M | 0.34% | +$3.38M |
| Keros Therapeutics, Inc.(KROS) | 293,200 | 210,000 | -83,200 | $17.03M | $3.32M | 0.33% | -$13.70M |
| Akero Therapeutics Inc | 0 | 82,000 | +82,000 | $0 | $2.28M | 0.23% | +$2.28M |
| Dyne Therapeutics, Inc.(DYN) | 165,000 | 96,000 | -69,000 | $5.93M | $2.26M | 0.23% | -$3.67M |
| Cogent Biosciences, Inc.(COGT) | 1,001,000 | 287,104 | -713,896 | $10.81M | $2.24M | 0.22% | -$8.57M |
| SCYNEXIS, Inc.(SCYX) | 1,448,728 | 1,228,910 | -219,818 | $2.16M | $1.49M | 0.15% | -$671.6K |
| Karyopharm Therapeutics Inc.(KPTI) | 2,018,500 | 2,018,500 | 0 | $1.68M | $1.37M | 0.14% | -$310.2K |
| Hyperfine, Inc.CL A(HYPR) | 1,188,178 | 1,188,178 | 0 | $1.28M | $1.05M | 0.10% | -$237.6K |
| Bluebird Bio Inc | 0 | 81,555 | +81,555 | $0 | $680.2K | 0.07% | +$680.2K |
| Alto Neuroscience, Inc.(ANRO) | 240,000 | 0 | -240,000 | $2.75M | $0 | — | -$2.75M |
| Apogee Therapeutics Inc | 154,000 | 0 | -154,000 | $9.05M | $0 | — | -$9.05M |
| argenx SEADR(ARGX) | 38,200 | 0 | -38,200 | $20.71M | $0 | — | -$20.71M |
| BioMarin Pharmaceutical Inc.(BMRN) | 320,000 | 0 | -320,000 | $22.49M | $0 | — | -$22.49M |
| BioNTech SEADS(BNTX) | 145,000 | 0 | -145,000 | $17.22M | $0 | — | -$17.22M |
| Bluebird Bio Inc | 1,631,143 | 0 | -1,631,143 | $847.4K | $0 | — | -$847.4K |
| Caremax IncCL A | 21,200 | 0 | -21,200 | $36.0K | $0 | — | -$36.0K |
| Cullinan Therapeutics, Inc.(CGEM) | 425,000 | 0 | -425,000 | $7.11M | $0 | — | -$7.11M |
| Cybin D/B/A Helus Pharma(HELP) | 918,000 | 0 | -918,000 | $8.16M | $0 | — | -$8.16M |
| Editas Medicine, Inc.(EDIT) | 1,465,000 | 0 | -1,465,000 | $5.00M | $0 | — | -$5.00M |
| Establishment Labs Holdings Inc.(ESTA) | 169,000 | 0 | -169,000 | $7.31M | $0 | — | -$7.31M |
| Immunocore Holdings plcADS(IMCR) | 200,000 | 0 | -200,000 | $6.23M | $0 | — | -$6.23M |
| Immunome, Inc.(IMNM) | 873,891 | 0 | -873,891 | $12.78M | $0 | — | -$12.78M |
| Immunovant, Inc.(IMVT) | 99,000 | 0 | -99,000 | $2.82M | $0 | — | -$2.82M |
| Instil Bio, Inc.(TIL) | 29,100 | 0 | -29,100 | $1.96M | $0 | — | -$1.96M |
| Kezar Life Sciences Inc | 5,026,000 | 0 | -5,026,000 | $3.89M | $0 | — | -$3.89M |
| Neumora Therapeutics, Inc.(NMRA) | 1,800,000 | 0 | -1,800,000 | $23.78M | $0 | — | -$23.78M |
| Neurogene Inc.(NGNE) | 425,041 | 0 | -425,041 | $17.83M | $0 | — | -$17.83M |
| Prelude Therapeutics Incorporated(PRLD) | 890,000 | 0 | -890,000 | $1.84M | $0 | — | -$1.84M |
| Prime Medicine, Inc.(PRME) | 694,000 | 0 | -694,000 | $2.69M | $0 | — | -$2.69M |
| Privia Health Group, Inc.(PRVA) | 466,800 | 0 | -466,800 | $8.50M | $0 | — | -$8.50M |
| SanofiADR(SNY) | 100,000 | 0 | -100,000 | $5.76M | $0 | — | -$5.76M |
| Structure Therapeutics IncADS | 430,900 | 0 | -430,900 | $18.91M | $0 | — | -$18.91M |
| Syros Pharmaceuticals Inc | 1,063,000 | 0 | -1,063,000 | $2.29M | $0 | — | -$2.29M |
| Terns Pharmaceuticals Inc | 2,133,872 | 0 | -2,133,872 | $17.80M | $0 | — | -$17.80M |
| Zoetis Inc.CL A(ZTS) | 71,000 | 0 | -71,000 | $13.87M | $0 | — | -$13.87M |