Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Revolution Medicines, Inc.(RVMD) | 2,000,000 | 2,000,000 | 0 | $159.30M | $194.50M | 10.02% | +$35.20M |
| Erasca, Inc.(ERAS) | 13,000,000 | 11,150,000 | -1,850,000 | $48.36M | $180.41M | 9.29% | +$132.05M |
| IDEAYA Biosciences, Inc.(IDYA) | 3,125,000 | 3,450,000 | +325,000 | $108.03M | $114.95M | 5.92% | +$6.92M |
| Praxis Precision Medicines, Inc.(PRAX) | 375,000 | 285,000 | -90,000 | $110.53M | $91.82M | 4.73% | -$18.70M |
| Centessa Pharmaceuticals PlcADS | 200,000 | 2,125,000 | +1,925,000 | $5.00M | $84.41M | 4.35% | +$79.40M |
| Terns Pharmaceuticals Inc | 750,000 | 1,500,000 | +750,000 | $30.30M | $79.08M | 4.07% | +$48.78M |
| ABIVAX Société AnonymeADS(ABVX) | 400,000 | 675,000 | +275,000 | $53.94M | $75.16M | 3.87% | +$21.22M |
| Tango Therapeutics, Inc.(TNGX) | 4,200,000 | 3,000,000 | -1,200,000 | $37.21M | $62.76M | 3.23% | +$25.55M |
| Cytokinetics, Incorporated(CYTK) | 300,000 | 875,000 | +575,000 | $19.06M | $57.67M | 2.97% | +$38.61M |
| Olema Pharmaceuticals, Inc.(OLMA) | 3,208,875 | 3,208,875 | 0 | $80.22M | $47.84M | 2.46% | -$32.38M |
| United Therapeutics Corporation(UTHR) | 0 | 80,000 | +80,000 | $0 | $47.44M | 2.44% | +$47.44M |
| Immunocore Holdings plcADS(IMCR) | 850,000 | 1,500,000 | +650,000 | $29.50M | $45.23M | 2.33% | +$15.72M |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 0 | 85,000 | +85,000 | $0 | $44.49M | 2.29% | +$44.49M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 190,000 | 450,000 | +260,000 | $20.34M | $39.14M | 2.02% | +$18.80M |
| CG Oncology, Inc.(CGON) | 200,000 | 575,000 | +375,000 | $8.30M | $38.92M | 2.00% | +$30.61M |
| Maze Therapeutics, Inc.(MAZE) | 950,000 | 1,235,000 | +285,000 | $39.36M | $36.86M | 1.90% | -$2.49M |
| Biogen Inc.(BIIB) | 200,000 | 200,000 | 0 | $35.20M | $36.67M | 1.89% | +$1.47M |
| Disc Medicine, Inc.(IRON) | 510,000 | 560,000 | +50,000 | $40.50M | $35.81M | 1.84% | -$4.69M |
| Dianthus Therapeutics, Inc.(DNTH) | 315,000 | 400,000 | +85,000 | $12.98M | $33.57M | 1.73% | +$20.59M |
| Ocular Therapeutix, Inc.(OCUL) | 3,500,000 | 3,850,000 | +350,000 | $42.49M | $32.61M | 1.68% | -$9.88M |
| Tyra Biosciences, Inc.(TYRA) | 210,000 | 850,000 | +640,000 | $5.52M | $32.55M | 1.68% | +$27.03M |
| Trevi Therapeutics, Inc.(TRVI) | 1,550,000 | 2,400,000 | +850,000 | $19.41M | $28.63M | 1.47% | +$9.23M |
| MoonLake ImmunotherapeuticsCL A(MLTX) | 1,750,000 | 1,500,000 | -250,000 | $23.07M | $27.96M | 1.44% | +$4.89M |
| Immunovant, Inc.(IMVT) | 1,375,000 | 1,075,000 | -300,000 | $34.95M | $26.70M | 1.38% | -$8.25M |
| Xenon Pharmaceuticals Inc.(XENE) | 0 | 450,000 | +450,000 | $0 | $26.17M | 1.35% | +$26.17M |
| Arcus Biosciences, Inc.(RCUS) | 0 | 1,200,000 | +1,200,000 | $0 | $25.92M | 1.33% | +$25.92M |
| Dyne Therapeutics, Inc.(DYN) | 1,250,000 | 1,400,000 | +150,000 | $24.45M | $25.38M | 1.31% | +$932.0K |
| Structure Therapeutics IncADS | 600,000 | 500,000 | -100,000 | $41.73M | $24.10M | 1.24% | -$17.63M |
| LB Pharmaceuticals Inc(LBRX) | 1,200,000 | 915,000 | -285,000 | $26.71M | $22.56M | 1.16% | -$4.15M |
| Enliven Therapeutics Inc | 340,000 | 540,000 | +200,000 | $5.24M | $21.17M | 1.09% | +$15.93M |
| Design Therapeutics, Inc.(DSGN) | 2,500,000 | 1,950,000 | -550,000 | $23.45M | $20.75M | 1.07% | -$2.70M |
| Minerva Neurosciences, Inc.(NERV) | 3,311,000 | 3,215,000 | -96,000 | $13.31M | $19.37M | 1.00% | +$6.06M |
| Newamsterdam Pharma Company ORDINARY SHARES | 450,000 | 600,000 | +150,000 | $15.79M | $19.21M | 0.99% | +$3.42M |
| Mirum Pharmaceuticals, Inc.(MIRM) | 225,000 | 200,000 | -25,000 | $17.77M | $18.48M | 0.95% | +$703.3K |
| Vaxcyte, Inc.(PCVX) | 650,000 | 300,000 | -350,000 | $29.99M | $17.43M | 0.90% | -$12.56M |
| Acadia Pharmaceuticals Inc | 850,000 | 750,000 | -100,000 | $22.70M | $16.70M | 0.86% | -$6.01M |
| Compass Therapeutics, Inc.(CMPX) | 1,150,000 | 3,150,000 | +2,000,000 | $6.18M | $16.66M | 0.86% | +$10.49M |
| Celldex Therapeutics, Inc.(CLDX) | 350,000 | 450,000 | +100,000 | $9.51M | $14.27M | 0.74% | +$4.77M |
| Janux Therapeutics, Inc.(JANX) | 1,000,000 | 1,000,000 | 0 | $13.80M | $13.90M | 0.72% | +$100.0K |
| Vor Biopharma Inc.(VOR) | 100,000 | 750,000 | +650,000 | $1.31M | $13.38M | 0.69% | +$12.07M |
| Alkermes plcSHS(ALKS) | 0 | 350,000 | +350,000 | $0 | $12.38M | 0.64% | +$12.38M |
| ORIC Pharmaceuticals, Inc.(ORIC) | 450,000 | 950,000 | +500,000 | $3.68M | $12.04M | 0.62% | +$8.36M |
| Immix Biopharma, Inc.(IMMX) | 1,000,000 | 1,225,000 | +225,000 | $5.23M | $11.16M | 0.57% | +$5.93M |
| Tenax Therapeutics, Inc.(TENX) | 0 | 625,000 | +625,000 | $0 | $9.99M | 0.51% | +$9.99M |
| Amylyx Pharmaceuticals, Inc.(AMLX) | 950,000 | 700,000 | -250,000 | $11.48M | $9.73M | 0.50% | -$1.75M |
| Crescent Biopharma, Inc.(CBIO) | 600,000 | 482,500 | -117,500 | $7.12M | $8.86M | 0.46% | +$1.75M |
| Soleno Therapeutics Inc | 300,000 | 250,000 | -50,000 | $13.89M | $8.37M | 0.43% | -$5.52M |
| ArriVent BioPharma, Inc.(AVBP) | 0 | 350,000 | +350,000 | $0 | $8.07M | 0.42% | +$8.07M |
| Relay Therapeutics, Inc.(RLAY) | 0 | 750,000 | +750,000 | $0 | $7.46M | 0.38% | +$7.46M |
| Corvus Pharmaceuticals, Inc.(CRVS) | 500,000 | 450,000 | -50,000 | $3.85M | $6.58M | 0.34% | +$2.73M |
| MeiraGTx Holdings plc(MGTX) | 0 | 700,000 | +700,000 | $0 | $6.06M | 0.31% | +$6.06M |
| Jade Biosciences Inc | 395,000 | 400,000 | +5,000 | $6.09M | $5.62M | 0.29% | -$474.9K |
| Verastem, Inc.(VSTM) | 1,700,000 | 1,000,000 | -700,000 | $13.12M | $5.30M | 0.27% | -$7.82M |
| Avalo Therapeutics, Inc.(AVTX) | 0 | 300,000 | +300,000 | $0 | $4.48M | 0.23% | +$4.48M |
| Unicycive Therapeutics, Inc.(UNCY) | 473,563 | 473,563 | 0 | $2.73M | $3.12M | 0.16% | +$383.6K |
| iBio, Inc.(IBIO) | 2,000,000 | 1,300,000 | -700,000 | $3.86M | $2.47M | 0.13% | -$1.39M |
| Palatin Technologies, Inc.(PTN) | 140,000 | 140,000 | 0 | $2.15M | $2.44M | 0.13% | +$285.6K |
| Aclaris Therapeutics, Inc.(ACRS) | 600,000 | 500,000 | -100,000 | $1.81M | $1.88M | 0.10% | +$69.0K |
| Pharvaris N V COM | 100,000 | 65,000 | -35,000 | $2.77M | $1.84M | 0.09% | -$938.8K |
| Veradermics, Incorporated(MANE) | 0 | 25,000 | +25,000 | $0 | $1.58M | 0.08% | +$1.58M |
| Faeth Therapeutics, Inc.(FTH) | 0 | 30,000 | +30,000 | $0 | $945.6K | 0.05% | +$945.6K |
| Septerna, Inc.(SEPN) | 23,548 | 23,548 | 0 | $656.5K | $565.9K | 0.03% | -$90.7K |
| Fractyl Health, Inc.(GUTS) | 1,100,000 | 1,000,000 | -100,000 | $2.42M | $457.8K | 0.02% | -$1.96M |
| Arcellx Inc COMMON STOCK | 115,000 | 0 | -115,000 | $7.50M | $0 | — | -$7.50M |
| Avidity Biosciences Inc | 500,000 | 0 | -500,000 | $36.06M | $0 | — | -$36.06M |
| Cidara Therapeutics Inc | 310,000 | 0 | -310,000 | $68.48M | $0 | — | -$68.48M |
| Day One Biopharmaceuticals I COM | 300,000 | 0 | -300,000 | $2.80M | $0 | — | -$2.80M |
| DBV Technologies S.A.ADS(DBVT) | 25,000 | 0 | -25,000 | $479.3K | $0 | — | -$479.3K |
| Jazz Pharmaceuticals plcSHS USD(JAZZ) | 200,000 | 0 | -200,000 | $34.00M | $0 | — | -$34.00M |
| Kiniksa Pharmaceuticals International, plcCL A(KNSA) | 350,000 | 0 | -350,000 | $14.44M | $0 | — | -$14.44M |
| Kymera Therapeutics, Inc.(KYMR) | 130,000 | 0 | -130,000 | $10.12M | $0 | — | -$10.12M |
| Mereo BioPharma Group plcADS(MREO) | 1,850,000 | 0 | -1,850,000 | $770.9K | $0 | — | -$770.9K |
| Neurogene Inc.(NGNE) | 195,000 | 0 | -195,000 | $4.02M | $0 | — | -$4.02M |
| Nurix Therapeutics, Inc.(NRIX) | 500,000 | 0 | -500,000 | $9.48M | $0 | — | -$9.48M |
| Nuvation Bio Inc.W EXP 02 10 202(NUVB) | 66,666 | 0 | -66,666 | $22.0K | $0 | — | -$22.0K |
| uniQure N.V.SHS(QURE) | 675,000 | 0 | -675,000 | $16.15M | $0 | — | -$16.15M |