Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q2 2025 ▲▼ | Q3 2025 ▲▼ | Change ▲▼ | Q2 2025 ▲▼ | Q3 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Revolution Medicines, Inc.(RVMD) | 1,700,000 | 1,750,000 | +50,000 | $62.54M | $81.72M | 8.07% | +$19.18M |
| IDEAYA Biosciences, Inc.(IDYA) | 3,345,000 | 2,250,000 | -1,095,000 | $70.31M | $61.22M | 6.05% | -$9.09M |
| Akero Therapeutics Inc | 1,200,000 | 1,200,000 | 0 | $64.03M | $56.98M | 5.63% | -$7.06M |
| Arvinas, Inc.(ARVN) | 3,300,000 | 5,575,000 | +2,275,000 | $24.29M | $47.50M | 4.69% | +$23.21M |
| Ocular Therapeutix, Inc.(OCUL) | 2,200,000 | 3,250,000 | +1,050,000 | $20.42M | $37.99M | 3.75% | +$17.58M |
| Cidara Therapeutics Inc | 190,000 | 375,000 | +185,000 | $9.25M | $35.91M | 3.55% | +$26.66M |
| Verastem, Inc.(VSTM) | 1,000,000 | 4,050,000 | +3,050,000 | $4.15M | $35.76M | 3.53% | +$31.61M |
| ABIVAX Société AnonymeADS(ABVX) | 0 | 415,000 | +415,000 | $0 | $35.23M | 3.48% | +$35.23M |
| Erasca, Inc.(ERAS) | 15,000,000 | 15,150,000 | +150,000 | $19.05M | $33.03M | 3.26% | +$13.98M |
| Maze Therapeutics, Inc.(MAZE) | 611,914 | 1,227,300 | +615,386 | $7.51M | $31.82M | 3.14% | +$24.32M |
| Olema Pharmaceuticals, Inc.(OLMA) | 3,208,875 | 3,208,875 | 0 | $13.67M | $31.41M | 3.10% | +$17.75M |
| Immunocore Holdings plcADS(IMCR) | 575,000 | 850,000 | +275,000 | $18.04M | $30.88M | 3.05% | +$12.84M |
| Dyne Therapeutics, Inc.(DYN) | 1,900,000 | 2,400,000 | +500,000 | $18.09M | $30.36M | 3.00% | +$12.27M |
| Disc Medicine, Inc.(IRON) | 700,000 | 450,000 | -250,000 | $37.07M | $29.74M | 2.94% | -$7.34M |
| Design Therapeutics, Inc.(DSGN) | 4,217,627 | 3,655,000 | -562,627 | $14.21M | $27.52M | 2.72% | +$13.31M |
| Jazz Pharmaceuticals plcSHS USD(JAZZ) | 450,000 | 200,000 | -250,000 | $47.75M | $26.36M | 2.60% | -$21.39M |
| Avidity Biosciences Inc | 950,000 | 600,000 | -350,000 | $26.98M | $26.14M | 2.58% | -$838.0K |
| Structure Therapeutics IncADS | 850,000 | 850,000 | 0 | $17.63M | $23.80M | 2.35% | +$6.17M |
| Janux Therapeutics, Inc.(JANX) | 1,000,000 | 935,000 | -65,000 | $23.10M | $22.85M | 2.26% | -$248.6K |
| Vaxcyte, Inc.(PCVX) | 0 | 625,000 | +625,000 | $0 | $22.51M | 2.22% | +$22.51M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 130,000 | 200,000 | +70,000 | $8.21M | $20.20M | 2.00% | +$11.98M |
| Trevi Therapeutics, Inc.(TRVI) | 850,000 | 2,200,000 | +1,350,000 | $4.65M | $20.13M | 1.99% | +$15.48M |
| Protagonist Therapeutics Inc | 0 | 300,000 | +300,000 | $0 | $19.93M | 1.97% | +$19.93M |
| Amylyx Pharmaceuticals, Inc.(AMLX) | 0 | 1,450,000 | +1,450,000 | $0 | $19.71M | 1.95% | +$19.71M |
| LB Pharmaceuticals Inc(LBRX) | 0 | 1,130,000 | +1,130,000 | $0 | $17.84M | 1.76% | +$17.84M |
| uniQure N.V.SHS(QURE) | 0 | 300,000 | +300,000 | $0 | $17.51M | 1.73% | +$17.51M |
| Kymera Therapeutics, Inc.(KYMR) | 0 | 250,000 | +250,000 | $0 | $14.15M | 1.40% | +$14.15M |
| Biogen Inc.(BIIB) | 200,000 | 100,000 | -100,000 | $25.12M | $14.01M | 1.38% | -$11.11M |
| Arcellx Inc COMMON STOCK | 0 | 165,000 | +165,000 | $0 | $13.55M | 1.34% | +$13.55M |
| Keros Therapeutics, Inc.(KROS) | 2,000,000 | 850,000 | -1,150,000 | $26.70M | $13.45M | 1.33% | -$13.25M |
| Centessa Pharmaceuticals PlcADS | 0 | 525,000 | +525,000 | $0 | $12.73M | 1.26% | +$12.73M |
| Tango Therapeutics, Inc.(TNGX) | 0 | 950,000 | +950,000 | $0 | $7.98M | 0.79% | +$7.98M |
| Dianthus Therapeutics, Inc.(DNTH) | 0 | 200,000 | +200,000 | $0 | $7.87M | 0.78% | +$7.87M |
| Cogent Biosciences, Inc.(COGT) | 0 | 500,000 | +500,000 | $0 | $7.18M | 0.71% | +$7.18M |
| Compass Therapeutics, Inc.(CMPX) | 0 | 2,050,000 | +2,050,000 | $0 | $7.17M | 0.71% | +$7.17M |
| Crescent Biopharma, Inc.(CBIO) | 553,686 | 600,000 | +46,314 | $8.94M | $7.13M | 0.70% | -$1.80M |
| Enliven Therapeutics Inc | 350,000 | 340,000 | -10,000 | $7.02M | $6.96M | 0.69% | -$61.2K |
| Immuneering CorpCL A | 0 | 950,000 | +950,000 | $0 | $6.65M | 0.66% | +$6.65M |
| Praxis Precision Medicines, Inc.(PRAX) | 225,000 | 125,000 | -100,000 | $9.46M | $6.63M | 0.65% | -$2.84M |
| Scholar Rock Holding Corporation(SRRK) | 0 | 175,000 | +175,000 | $0 | $6.52M | 0.64% | +$6.52M |
| Jade Biosciences Inc | 625,000 | 625,000 | 0 | $6.24M | $5.39M | 0.53% | -$850.0K |
| Eupraxia Pharmaceuticals Inc.(EPRX) | 0 | 900,000 | +900,000 | $0 | $5.31M | 0.52% | +$5.31M |
| Immunovant, Inc.(IMVT) | 275,000 | 275,000 | 0 | $4.40M | $4.43M | 0.44% | +$33.0K |
| Pharvaris N V COM | 0 | 150,000 | +150,000 | $0 | $3.74M | 0.37% | +$3.74M |
| Astria Therapeutics Inc | 700,000 | 500,000 | -200,000 | $3.75M | $3.64M | 0.36% | -$112.0K |
| PepGen Inc.(PEPG) | 0 | 750,000 | +750,000 | $0 | $3.46M | 0.34% | +$3.46M |
| Aclaris Therapeutics, Inc.(ACRS) | 1,850,000 | 1,500,000 | -350,000 | $2.63M | $2.85M | 0.28% | +$223.0K |
| Unicycive Therapeutics, Inc.(UNCY) | 473,562 | 473,563 | +1 | $2.26M | $2.06M | 0.20% | -$194.2K |
| Esperion Therapeutics Inc Ne | 0 | 750,000 | +750,000 | $0 | $1.99M | 0.20% | +$1.99M |
| Septerna, Inc.(SEPN) | 109,202 | 83,548 | -25,654 | $1.15M | $1.57M | 0.16% | +$417.3K |
| Mereo BioPharma Group plcADS(MREO) | 0 | 500,000 | +500,000 | $0 | $1.03M | 0.10% | +$1.03M |
| Fractyl Health, Inc.(GUTS) | 0 | 500,000 | +500,000 | $0 | $795.0K | 0.08% | +$795.0K |
| Nuvation Bio Inc.W EXP 02 10 202(NUVB) | 66,666 | 66,666 | 0 | $18.0K | $13.5K | 0.00% | -$4.5K |
| Annexon, Inc.(ANNX) | 2,410,000 | 0 | -2,410,000 | $5.78M | $0 | — | -$5.78M |
| Bicara Therapeutics Inc | 400,000 | 0 | -400,000 | $3.72M | $0 | — | -$3.72M |
| Biohaven Ltd.(BHVN) | 700,000 | 0 | -700,000 | $9.88M | $0 | — | -$9.88M |
| Celldex Therapeutics, Inc.(CLDX) | 600,000 | 0 | -600,000 | $12.21M | $0 | — | -$12.21M |
| Krystal Biotech, Inc.(KRYS) | 100,000 | 0 | -100,000 | $13.75M | $0 | — | -$13.75M |
| Legend Biotech CorporationADS(LEGN) | 250,000 | 0 | -250,000 | $8.87M | $0 | — | -$8.87M |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 50,000 | 0 | -50,000 | $15.13M | $0 | — | -$15.13M |
| Metsera Inc | 200,000 | 0 | -200,000 | $5.69M | $0 | — | -$5.69M |
| MoonLake ImmunotherapeuticsCL A(MLTX) | 200,000 | 0 | -200,000 | $9.44M | $0 | — | -$9.44M |
| Neurocrine Biosciences, Inc.(NBIX) | 150,000 | 0 | -150,000 | $18.85M | $0 | — | -$18.85M |
| Rapport Therapeutics, Inc.(RAPP) | 208,910 | 0 | -208,910 | $2.38M | $0 | — | -$2.38M |
| United Therapeutics Corporation(UTHR) | 85,000 | 0 | -85,000 | $24.42M | $0 | — | -$24.42M |
| Xencor, Inc.(XNCR) | 1,250,000 | 0 | -1,250,000 | $9.82M | $0 | — | -$9.82M |