Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Revolution Medicines, Inc.(RVMD) | 1,750,000 | 2,000,000 | +250,000 | $81.72M | $159.30M | 10.62% | +$77.58M |
| Praxis Precision Medicines, Inc.(PRAX) | 125,000 | 375,000 | +250,000 | $6.63M | $110.53M | 7.37% | +$103.90M |
| IDEAYA Biosciences, Inc.(IDYA) | 2,250,000 | 3,125,000 | +875,000 | $61.22M | $108.03M | 7.20% | +$46.81M |
| Olema Pharmaceuticals, Inc.(OLMA) | 3,208,875 | 3,208,875 | 0 | $31.41M | $80.22M | 5.35% | +$48.81M |
| Cidara Therapeutics Inc | 375,000 | 310,000 | -65,000 | $35.91M | $68.48M | 4.56% | +$32.57M |
| ABIVAX Société AnonymeADS(ABVX) | 415,000 | 400,000 | -15,000 | $35.23M | $53.94M | 3.59% | +$18.71M |
| Erasca, Inc.(ERAS) | 15,150,000 | 13,000,000 | -2,150,000 | $33.03M | $48.36M | 3.22% | +$15.33M |
| Ocular Therapeutix, Inc.(OCUL) | 3,250,000 | 3,500,000 | +250,000 | $37.99M | $42.49M | 2.83% | +$4.50M |
| Structure Therapeutics IncADS | 850,000 | 600,000 | -250,000 | $23.80M | $41.73M | 2.78% | +$17.93M |
| Disc Medicine, Inc.(IRON) | 450,000 | 510,000 | +60,000 | $29.74M | $40.50M | 2.70% | +$10.76M |
| Maze Therapeutics, Inc.(MAZE) | 1,227,300 | 950,000 | -277,300 | $31.82M | $39.36M | 2.62% | +$7.53M |
| Tango Therapeutics, Inc.(TNGX) | 950,000 | 4,200,000 | +3,250,000 | $7.98M | $37.21M | 2.48% | +$29.23M |
| Avidity Biosciences Inc | 600,000 | 500,000 | -100,000 | $26.14M | $36.06M | 2.40% | +$9.92M |
| Biogen Inc.(BIIB) | 100,000 | 200,000 | +100,000 | $14.01M | $35.20M | 2.35% | +$21.19M |
| Immunovant, Inc.(IMVT) | 275,000 | 1,375,000 | +1,100,000 | $4.43M | $34.95M | 2.33% | +$30.52M |
| Jazz Pharmaceuticals plcSHS USD(JAZZ) | 200,000 | 200,000 | 0 | $26.36M | $34.00M | 2.27% | +$7.64M |
| Terns Pharmaceuticals Inc | 0 | 750,000 | +750,000 | $0 | $30.30M | 2.02% | +$30.30M |
| Vaxcyte, Inc.(PCVX) | 625,000 | 650,000 | +25,000 | $22.51M | $29.99M | 2.00% | +$7.48M |
| Immunocore Holdings plcADS(IMCR) | 850,000 | 850,000 | 0 | $30.88M | $29.50M | 1.97% | -$1.38M |
| LB Pharmaceuticals Inc(LBRX) | 1,130,000 | 1,200,000 | +70,000 | $17.84M | $26.71M | 1.78% | +$8.87M |
| Dyne Therapeutics, Inc.(DYN) | 2,400,000 | 1,250,000 | -1,150,000 | $30.36M | $24.45M | 1.63% | -$5.91M |
| Design Therapeutics, Inc.(DSGN) | 3,655,000 | 2,500,000 | -1,155,000 | $27.52M | $23.45M | 1.56% | -$4.07M |
| MoonLake ImmunotherapeuticsCL A(MLTX) | 0 | 1,750,000 | +1,750,000 | $0 | $23.07M | 1.54% | +$23.07M |
| Acadia Pharmaceuticals Inc | 0 | 850,000 | +850,000 | $0 | $22.70M | 1.51% | +$22.70M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 200,000 | 190,000 | -10,000 | $20.20M | $20.34M | 1.36% | +$139.6K |
| Trevi Therapeutics, Inc.(TRVI) | 2,200,000 | 1,550,000 | -650,000 | $20.13M | $19.41M | 1.29% | -$724.0K |
| Cytokinetics, Incorporated(CYTK) | 0 | 300,000 | +300,000 | $0 | $19.06M | 1.27% | +$19.06M |
| Mirum Pharmaceuticals, Inc.(MIRM) | 0 | 225,000 | +225,000 | $0 | $17.77M | 1.18% | +$17.77M |
| uniQure N.V.SHS(QURE) | 300,000 | 675,000 | +375,000 | $17.51M | $16.15M | 1.08% | -$1.36M |
| Newamsterdam Pharma Company ORDINARY SHARES | 0 | 450,000 | +450,000 | $0 | $15.79M | 1.05% | +$15.79M |
| Kiniksa Pharmaceuticals International, plcCL A(KNSA) | 0 | 350,000 | +350,000 | $0 | $14.44M | 0.96% | +$14.44M |
| Soleno Therapeutics Inc | 0 | 300,000 | +300,000 | $0 | $13.89M | 0.93% | +$13.89M |
| Janux Therapeutics, Inc.(JANX) | 935,000 | 1,000,000 | +65,000 | $22.85M | $13.80M | 0.92% | -$9.05M |
| Minerva Neurosciences, Inc.(NERV) | 0 | 3,311,000 | +3,311,000 | $0 | $13.31M | 0.89% | +$13.31M |
| Verastem, Inc.(VSTM) | 4,050,000 | 1,700,000 | -2,350,000 | $35.76M | $13.12M | 0.87% | -$22.64M |
| Dianthus Therapeutics, Inc.(DNTH) | 200,000 | 315,000 | +115,000 | $7.87M | $12.98M | 0.87% | +$5.11M |
| Amylyx Pharmaceuticals, Inc.(AMLX) | 1,450,000 | 950,000 | -500,000 | $19.71M | $11.48M | 0.76% | -$8.23M |
| Kymera Therapeutics, Inc.(KYMR) | 250,000 | 130,000 | -120,000 | $14.15M | $10.12M | 0.67% | -$4.03M |
| Celldex Therapeutics, Inc.(CLDX) | 0 | 350,000 | +350,000 | $0 | $9.51M | 0.63% | +$9.51M |
| Nurix Therapeutics, Inc.(NRIX) | 0 | 500,000 | +500,000 | $0 | $9.48M | 0.63% | +$9.48M |
| CG Oncology, Inc.(CGON) | 0 | 200,000 | +200,000 | $0 | $8.30M | 0.55% | +$8.30M |
| Arcellx Inc COMMON STOCK | 165,000 | 115,000 | -50,000 | $13.55M | $7.50M | 0.50% | -$6.05M |
| Crescent Biopharma, Inc.(CBIO) | 600,000 | 600,000 | 0 | $7.13M | $7.12M | 0.47% | -$18.0K |
| Compass Therapeutics, Inc.(CMPX) | 2,050,000 | 1,150,000 | -900,000 | $7.17M | $6.18M | 0.41% | -$999.5K |
| Jade Biosciences Inc | 625,000 | 395,000 | -230,000 | $5.39M | $6.09M | 0.41% | +$701.1K |
| Tyra Biosciences, Inc.(TYRA) | 0 | 210,000 | +210,000 | $0 | $5.52M | 0.37% | +$5.52M |
| Enliven Therapeutics Inc | 340,000 | 340,000 | 0 | $6.96M | $5.24M | 0.35% | -$1.72M |
| Immix Biopharma, Inc.(IMMX) | 0 | 1,000,000 | +1,000,000 | $0 | $5.23M | 0.35% | +$5.23M |
| Centessa Pharmaceuticals PlcADS | 525,000 | 200,000 | -325,000 | $12.73M | $5.00M | 0.33% | -$7.73M |
| Neurogene Inc.(NGNE) | 0 | 195,000 | +195,000 | $0 | $4.02M | 0.27% | +$4.02M |
| iBio, Inc.(IBIO) | 0 | 2,000,000 | +2,000,000 | $0 | $3.86M | 0.26% | +$3.86M |
| Corvus Pharmaceuticals, Inc.(CRVS) | 0 | 500,000 | +500,000 | $0 | $3.85M | 0.26% | +$3.85M |
| ORIC Pharmaceuticals, Inc.(ORIC) | 0 | 450,000 | +450,000 | $0 | $3.68M | 0.25% | +$3.68M |
| Day One Biopharmaceuticals I COM | 0 | 300,000 | +300,000 | $0 | $2.80M | 0.19% | +$2.80M |
| Pharvaris N V COM | 150,000 | 100,000 | -50,000 | $3.74M | $2.77M | 0.18% | -$967.5K |
| Unicycive Therapeutics, Inc.(UNCY) | 473,563 | 473,563 | 0 | $2.06M | $2.73M | 0.18% | +$667.7K |
| Fractyl Health, Inc.(GUTS) | 500,000 | 1,100,000 | +600,000 | $795.0K | $2.42M | 0.16% | +$1.63M |
| Palatin Technologies, Inc.(PTN) | 0 | 140,000 | +140,000 | $0 | $2.15M | 0.14% | +$2.15M |
| Aclaris Therapeutics, Inc.(ACRS) | 1,500,000 | 600,000 | -900,000 | $2.85M | $1.81M | 0.12% | -$1.04M |
| Vor Biopharma Inc.(VOR) | 0 | 100,000 | +100,000 | $0 | $1.31M | 0.09% | +$1.31M |
| Mereo BioPharma Group plcADS(MREO) | 500,000 | 1,850,000 | +1,350,000 | $1.03M | $770.9K | 0.05% | -$259.1K |
| Septerna, Inc.(SEPN) | 83,548 | 23,548 | -60,000 | $1.57M | $656.5K | 0.04% | -$915.0K |
| DBV Technologies S.A.ADS(DBVT) | 0 | 25,000 | +25,000 | $0 | $479.3K | 0.03% | +$479.3K |
| Nuvation Bio Inc.W EXP 02 10 202(NUVB) | 66,666 | 66,666 | 0 | $13.5K | $22.0K | 0.00% | +$8.5K |
| Akero Therapeutics Inc | 1,200,000 | 0 | -1,200,000 | $56.98M | $0 | — | -$56.98M |
| Arvinas, Inc.(ARVN) | 5,575,000 | 0 | -5,575,000 | $47.50M | $0 | — | -$47.50M |
| Astria Therapeutics Inc | 500,000 | 0 | -500,000 | $3.64M | $0 | — | -$3.64M |
| Cogent Biosciences, Inc.(COGT) | 500,000 | 0 | -500,000 | $7.18M | $0 | — | -$7.18M |
| Esperion Therapeutics Inc Ne | 750,000 | 0 | -750,000 | $1.99M | $0 | — | -$1.99M |
| Eupraxia Pharmaceuticals Inc.(EPRX) | 900,000 | 0 | -900,000 | $5.31M | $0 | — | -$5.31M |
| Immuneering CorpCL A | 950,000 | 0 | -950,000 | $6.65M | $0 | — | -$6.65M |
| Keros Therapeutics, Inc.(KROS) | 850,000 | 0 | -850,000 | $13.45M | $0 | — | -$13.45M |
| PepGen Inc.(PEPG) | 750,000 | 0 | -750,000 | $3.46M | $0 | — | -$3.46M |
| Protagonist Therapeutics Inc | 300,000 | 0 | -300,000 | $19.93M | $0 | — | -$19.93M |
| Scholar Rock Holding Corporation(SRRK) | 175,000 | 0 | -175,000 | $6.52M | $0 | — | -$6.52M |