Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| UNITED THERAPEUTICS CORP DEL(UTHR) | 60,000 | 187,187 | +127,187 | 29,235 | 110,998 | 4.50% | +81,763 |
| INSULET CORP(PODD) | 150,000 | 562,500 | +412,500 | 42,636 | 118,035 | 4.78% | +75,399 |
| KRYSTAL BIOTECH INC(KRYS) | 941,059 | 1,153,087 | +212,028 | 232,009 | 297,865 | 12.06% | +65,857 |
| VERICEL CORP(VCEL) | 764,000 | 2,549,079 | +1,785,079 | 27,512 | 82,004 | 3.32% | +54,492 |
| TG THERAPEUTICS INC(TGTX) | 3,139,312 | 4,029,319 | +890,007 | 93,583 | 133,854 | 5.42% | +40,271 |
| INDIVIOR PHARMACEUTICALS INC(INDV) | 0 | 1,274,000 | +1,274,000 | 0 | 38,832 | 1.57% | +38,832 |
| PROGYNY INC | 0 | 2,067,000 | +2,067,000 | 0 | 35,098 | 1.42% | +35,098 |
| ALKERMES PLC(ALKS) | 1,322,364 | 1,970,864 | +648,500 | 37,000 | 69,690 | 2.82% | +32,690 |
| GERON CORP(GERN) | 23,290,000 | 41,508,659 | +18,218,659 | 30,743 | 61,848 | 2.50% | +31,105 |
| ANI PHARMACEUTICALS INC(ANIP) | 486,243 | 820,243 | +334,000 | 38,384 | 63,077 | 2.55% | +24,693 |
| MERCK & CO INC(MRK) | 0 | 203,000 | +203,000 | 0 | 24,419 | 0.99% | +24,419 |
| EDGEWISE THERAPEUTICS INC(EWTX) | 910,000 | 1,449,915 | +539,915 | 22,582 | 45,672 | 1.85% | +23,091 |
| ICON PLC(ICLR) | 0 | 192,000 | +192,000 | 0 | 21,247 | 0.86% | +21,247 |
| NATERA INC(NTRA) | 20,000 | 119,000 | +99,000 | 4,582 | 23,799 | 0.96% | +19,217 |
| CONTEXT THERAPEUTICS INC(CNTX) | 0 | 6,963,141 | +6,963,141 | 0 | 18,243 | 0.74% | +18,243 |
| VIR BIOTECHNOLOGY INC(VIR) | 0 | 2,002,000 | +2,002,000 | 0 | 17,938 | 0.73% | +17,938 |
| XENON PHARMACEUTICALS INC(XENE) | 0 | 292,000 | +292,000 | 0 | 16,980 | 0.69% | +16,980 |
| TRAVERE THERAPEUTICS INC(TVTX) | 0 | 546,000 | +546,000 | 0 | 16,222 | 0.66% | +16,222 |
| ALNYLAM PHARMACEUTICALS INC(ALNY) | 70,000 | 131,650 | +61,650 | 27,836 | 43,559 | 1.76% | +15,724 |
| TANDEM DIABETES CARE INC(TNDM) | 0 | 783,000 | +783,000 | 0 | 15,010 | 0.61% | +15,010 |
| CORCEPT THERAPEUTICS INC(CORT) | 0 | 285,531 | +285,531 | 0 | 11,510 | 0.47% | +11,510 |
| CERUS CORP(CERS) | 4,000,000 | 10,753,700 | +6,753,700 | 8,240 | 19,572 | 0.79% | +11,332 |
| VERACYTE INC(VCYT) | 10,000 | 319,912 | +309,912 | 421 | 10,304 | 0.42% | +9,883 |
| UROGEN PHARMA LTD(URGN) | 150,000 | 727,000 | +577,000 | 3,513 | 13,071 | 0.53% | +9,558 |
| TANGO THERAPEUTICS INC(TNGX) | 10,000 | 450,000 | +440,000 | 89 | 9,414 | 0.38% | +9,325 |
| SOPHIA GENETICS SA(SOPH) | 0 | 1,850,000 | +1,850,000 | 0 | 9,158 | 0.37% | +9,158 |
| TREVI THERAPEUTICS INC(TRVI) | 900,000 | 1,620,000 | +720,000 | 11,268 | 19,327 | 0.78% | +8,059 |
| INHIBRX BIOSCIENCES INC(INBX) | 25,000 | 131,000 | +106,000 | 1,975 | 8,807 | 0.36% | +6,832 |
| BIODESIX INC(BDSX) | 0 | 416,599 | +416,599 | 0 | 6,041 | 0.24% | +6,041 |
| RELMADA THERAPEUTICS INC(RLMD) | 0 | 842,106 | +842,106 | 0 | 5,861 | 0.24% | +5,861 |
| CULLINAN THERAPEUTICS INC(CGEM) | 0 | 410,200 | +410,200 | 0 | 5,829 | 0.24% | +5,829 |
| IMMUNIC INC(IMUX) | 0 | 4,500,000 | +4,500,000 | 0 | 4,995 | 0.20% | +4,995 |
| LARIMAR THERAPEUTICS INC(LRMR) | 0 | 1,066,960 | +1,066,960 | 0 | 4,801 | 0.19% | +4,801 |
| ETON PHARMACEUTICALS INC(ETON) | 0 | 166,381 | +166,381 | 0 | 4,106 | 0.17% | +4,106 |
| NOVOCURE LTD(NVCR) | 8,530,665 | 10,492,391 | +1,961,726 | 110,301 | 114,367 | 4.63% | +4,066 |
| SAB BIOTHERAPEUTICS INC(SABS) | 0 | 1,050,000 | +1,050,000 | 0 | 4,022 | 0.16% | +4,022 |
| PROCEPT BIOROBOTICS CORP(PRCT) | 0 | 160,000 | +160,000 | 0 | 4,002 | 0.16% | +4,002 |
| TECTONIC THERAPEUTIC INC(TECX) | 0 | 121,684 | +121,684 | 0 | 3,761 | 0.15% | +3,761 |
| IOVANCE BIOTHERAPEUTICS INC(IOVA) | 0 | 1,000,000 | +1,000,000 | 0 | 3,510 | 0.14% | +3,510 |
| EDAP TMS S A(FOCL) | 7,309,254 | 7,309,254 | 0 | 24,047 | 27,190 | 1.10% | +3,143 |
| C4 THERAPEUTICS INC(CCCC) | 3,803,942 | 3,803,942 | 0 | 7,266 | 10,004 | 0.41% | +2,739 |
| SATELLOS BIOSCIENCE INC(MSLE) | 0 | 414,359 | +414,359 | 0 | 2,333 | 0.09% | +2,333 |
| EVOLUS INC(EOLS) | 1,070,000 | 2,245,360 | +1,175,360 | 7,116 | 9,228 | 0.37% | +2,113 |
| INSPIRE MED SYS INC(INSP) | 299,399 | 576,299 | +276,900 | 27,614 | 29,726 | 1.20% | +2,112 |
| LIVANOVA PLC(LIVN) | 567,500 | 582,500 | +15,000 | 34,918 | 37,024 | 1.50% | +2,105 |
| ARROWHEAD PHARMACEUTICALS IN(ARWR) | 0 | 28,479 | +28,479 | 0 | 1,786 | 0.07% | +1,786 |
| CYTOMX THERAPEUTICS INC.(CTMX) | 0 | 300,000 | +300,000 | 0 | 1,410 | 0.06% | +1,410 |
| KINIKSA PHARMACEUTICALS INTL(KNSA) | 587,000 | 521,353 | -65,647 | 24,214 | 25,103 | 1.02% | +889 |
| SIONNA THERAPEUTICS INC(SION) | 268,500 | 293,500 | +25,000 | 11,046 | 11,766 | 0.48% | +720 |
| ORTHOPEDIATRICS CORP(KIDS) | 525,447 | 615,447 | +90,000 | 9,332 | 9,767 | 0.40% | +435 |
| PHARVARIS N V COM | 702,052 | 702,052 | 0 | 19,482 | 19,833 | 0.80% | +351 |
| RAPPORT THERAPEUTICS INC(RAPP) | 0 | 10,000 | +10,000 | 0 | 313 | 0.01% | +313 |
| QUOIN PHARMACEUTICALS LTD(QNRX) | 25,000 | 72,730 | +47,730 | 361 | 480 | 0.02% | +119 |
| LB PHARMACEUTICALS INC(LBRX) | 10,000 | 10,000 | 0 | 223 | 247 | 0.01% | +24 |
| DELCATH SYS INC(DCTH) | 10,000 | 0 | -10,000 | 101 | 0 | — | -101 |
| JASPER THERAPEUTICS INC(JSPR) | 200,000 | 276,312 | +76,312 | 366 | 242 | 0.01% | -124 |
| DYNE THERAPEUTICS INC(DYN) | 10,000 | 0 | -10,000 | 196 | 0 | — | -196 |
| STAAR SURGICAL CO(STAA) | 25,000 | 20,000 | -5,000 | 577 | 374 | 0.02% | -203 |
| MADRIGAL PHARMACEUTICALS INC(MDGL) | 500 | 0 | -500 | 291 | 0 | — | -291 |
| INSPIREMD INC(NSPR) | 1,150,000 | 1,045,708 | -104,292 | 2,047 | 1,705 | 0.07% | -342 |
| PRAXIS PRECISION MEDICINES I(PRAX) | 362,966 | 330,517 | -32,449 | 106,981 | 106,489 | 4.31% | -491 |
| TWIST BIOSCIENCE CORP(TWST) | 1,861,802 | 1,226,629 | -635,173 | 59,056 | 58,289 | 2.36% | -767 |
| KARYOPHARM THERAPEUTICS INC(KPTI) | 440,000 | 440,000 | 0 | 3,238 | 2,451 | 0.10% | -788 |
| FRACTYL HEALTH INC(GUTS) | 400,000 | 0 | -400,000 | 880 | 0 | — | -880 |
| PULMONX CORP(LUNG) | 2,038,323 | 2,788,323 | +750,000 | 4,505 | 3,597 | 0.15% | -908 |
| GRAIL INC(GRAL) | 11,000 | 0 | -11,000 | 941 | 0 | — | -941 |
| JADE BIOSCIENCES INC | 796,744 | 796,744 | 0 | 12,294 | 11,194 | 0.45% | -1,100 |
| AVALO THERAPEUTICS INC(AVTX) | 441,978 | 441,978 | 0 | 8,026 | 6,599 | 0.27% | -1,428 |
| KODIAK SCIENCES INC(KOD) | 60,000 | 0 | -60,000 | 1,678 | 0 | — | -1,678 |
| BICARA THERAPEUTICS INC | 100,000 | 0 | -100,000 | 1,683 | 0 | — | -1,683 |
| OLEMA PHARMACEUTICALS INC(OLMA) | 69,874 | 0 | -69,874 | 1,747 | 0 | — | -1,747 |
| ARCELLX INC COMMON STOCK | 30,000 | 0 | -30,000 | 1,956 | 0 | — | -1,956 |
| QUIDELORTHO CORP(QDEL) | 75,000 | 0 | -75,000 | 2,142 | 0 | — | -2,142 |
| ZYMEWORKS INC(ZYME) | 100,000 | 10,000 | -90,000 | 2,633 | 250 | 0.01% | -2,383 |
| STRUCTURE THERAPEUTICS INC | 90,000 | 80,000 | -10,000 | 6,260 | 3,856 | 0.16% | -2,403 |
| VIKING THERAPEUTICS INC(VKTX) | 70,000 | 0 | -70,000 | 2,463 | 0 | — | -2,463 |
| TYRA BIOSCIENCES INC(TYRA) | 125,000 | 10,000 | -115,000 | 3,286 | 383 | 0.02% | -2,903 |
| NEUROPACE INC(NPCE) | 2,703,208 | 2,932,207 | +228,999 | 41,738 | 38,559 | 1.56% | -3,179 |
| INDIVIOR PLC | 100,000 | 0 | -100,000 | 3,588 | 0 | — | -3,588 |
| NEOGENOMICS INC(NEO) | 427,504 | 175,000 | -252,504 | 5,027 | 1,299 | 0.05% | -3,729 |
| COGENT BIOSCIENCES INC(COGT) | 120,000 | 10,000 | -110,000 | 4,262 | 385 | 0.02% | -3,877 |
| INHIBIKASE THERAPEUTICS INC(IKT) | 10,875,000 | 10,875,000 | 0 | 22,294 | 18,270 | 0.74% | -4,024 |
| SEPTERNA INC(SEPN) | 383,368 | 275,000 | -108,368 | 10,688 | 6,608 | 0.27% | -4,080 |
| CALCIMEDICA INC(CALC) | 683,904 | 0 | -683,904 | 4,507 | 0 | — | -4,507 |
| MOONLAKE IMMUNOTHERAPEUTICS(MLTX) | 400,000 | 0 | -400,000 | 5,272 | 0 | — | -5,272 |
| ORUKA THERAPEUTICS INC(ORKA) | 190,000 | 5,000 | -185,000 | 5,759 | 245 | 0.01% | -5,514 |
| VAXCYTE INC(PCVX) | 608,958 | 385,472 | -223,486 | 28,097 | 22,400 | 0.91% | -5,698 |
| CG ONCOLOGY INC(CGON) | 170,000 | 20,000 | -150,000 | 7,058 | 1,354 | 0.05% | -5,705 |
| ABIVAX SA(ABVX) | 45,000 | 0 | -45,000 | 6,068 | 0 | — | -6,068 |
| ANAPTYSBIO INC | 135,000 | 6,000 | -129,000 | 6,545 | 333 | 0.01% | -6,212 |
| BELITE BIO INC(BLTE) | 40,354 | 0 | -40,354 | 6,455 | 0 | — | -6,455 |
| ENLIVEN THERAPEUTICS INC | 1,025,000 | 230,869 | -794,131 | 15,785 | 9,050 | 0.37% | -6,735 |
| INSMED INC(INSM) | 48,500 | 10,250 | -38,250 | 8,441 | 1,676 | 0.07% | -6,765 |
| SYNDAX PHARMACEUTICALS INC(SNDX) | 2,247,110 | 1,726,908 | -520,202 | 47,212 | 40,341 | 1.63% | -6,871 |
| ARCUS BIOSCIENCES INC(RCUS) | 711,983 | 451,983 | -260,000 | 16,967 | 9,763 | 0.40% | -7,204 |
| MBX BIOSCIENCES INC(MBX) | 408,900 | 178,897 | -230,003 | 12,897 | 5,340 | 0.22% | -7,557 |
| ERASCA INC(ERAS) | 2,162,162 | 0 | -2,162,162 | 8,043 | 0 | — | -8,043 |
| MIRUM PHARMACEUTICALS INC(MIRM) | 573,614 | 400,306 | -173,308 | 45,310 | 36,980 | 1.50% | -8,330 |
| CIDARA THERAPEUTICS INC | 38,811 | 0 | -38,811 | 8,573 | 0 | — | -8,573 |
| NURIX THERAPEUTICS INC(NRIX) | 1,219,394 | 938,163 | -281,231 | 23,132 | 14,542 | 0.59% | -8,590 |