Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Krystal Biotech, Inc.(KRYS) | 941,059 | 1,153,087 | +212,028 | $232.01M | $297.87M | 12.06% | +$65.86M |
| Celcuity Inc.(CELC) | 1,808,258 | 1,284,378 | -523,880 | $180.36M | $146.60M | 5.94% | -$33.76M |
| TG Therapeutics, Inc.(TGTX) | 3,139,312 | 4,029,319 | +890,007 | $93.58M | $133.85M | 5.42% | +$40.27M |
| Insulet Corporation(PODD) | 150,000 | 562,500 | +412,500 | $42.64M | $118.03M | 4.78% | +$75.40M |
| NovoCure Limited(NVCR) | 8,530,665 | 10,492,391 | +1,961,726 | $110.30M | $114.37M | 4.63% | +$4.07M |
| United Therapeutics Corporation(UTHR) | 60,000 | 187,187 | +127,187 | $29.23M | $111.00M | 4.50% | +$81.76M |
| Praxis Precision Medicines, Inc.(PRAX) | 362,966 | 330,517 | -32,449 | $106.98M | $106.49M | 4.31% | -$491.3K |
| Vericel Corporation(VCEL) | 764,000 | 2,549,079 | +1,785,079 | $27.51M | $82.00M | 3.32% | +$54.49M |
| Alkermes plcSHS(ALKS) | 1,322,364 | 1,970,864 | +648,500 | $37.00M | $69.69M | 2.82% | +$32.69M |
| ANI Pharmaceuticals, Inc.(ANIP) | 486,243 | 820,243 | +334,000 | $38.38M | $63.08M | 2.55% | +$24.69M |
| Globus Medical, Inc.CL A(GMED) | 887,000 | 729,467 | -157,533 | $77.44M | $62.85M | 2.55% | -$14.59M |
| Geron Corporation(GERN) | 23,290,000 | 41,508,659 | +18,218,659 | $30.74M | $61.85M | 2.50% | +$31.11M |
| Twist Bioscience Corporation(TWST) | 1,861,802 | 1,226,629 | -635,173 | $59.06M | $58.29M | 2.36% | -$766.9K |
| Edgewise Therapeutics, Inc.(EWTX) | 910,000 | 1,449,915 | +539,915 | $22.58M | $45.67M | 1.85% | +$23.09M |
| Beta Bionics, Inc.(BBNX) | 2,534,565 | 4,354,501 | +1,819,936 | $77.23M | $43.63M | 1.77% | -$33.60M |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 70,000 | 131,650 | +61,650 | $27.84M | $43.56M | 1.76% | +$15.72M |
| Syndax Pharmaceuticals, Inc.(SNDX) | 2,247,110 | 1,726,908 | -520,202 | $47.21M | $40.34M | 1.63% | -$6.87M |
| Indivior Pharmaceuticals, Inc.(INDV) | 0 | 1,274,000 | +1,274,000 | $0 | $38.83M | 1.57% | +$38.83M |
| NeuroPace, Inc.(NPCE) | 2,703,208 | 2,932,207 | +228,999 | $41.74M | $38.56M | 1.56% | -$3.18M |
| LivaNova PLCSHS(LIVN) | 567,500 | 582,500 | +15,000 | $34.92M | $37.02M | 1.50% | +$2.11M |
| Mirum Pharmaceuticals, Inc.(MIRM) | 573,614 | 400,306 | -173,308 | $45.31M | $36.98M | 1.50% | -$8.33M |
| BioMarin Pharmaceutical Inc.(BMRN) | 1,320,000 | 650,572 | -669,428 | $78.45M | $36.75M | 1.49% | -$41.70M |
| Progyny Inc | 0 | 2,067,000 | +2,067,000 | $0 | $35.10M | 1.42% | +$35.10M |
| Inspire Medical Systems, Inc.(INSP) | 299,399 | 576,299 | +276,900 | $27.61M | $29.73M | 1.20% | +$2.11M |
| EDAP TMS S.A.ADR(FOCL) | 7,309,254 | 7,309,254 | 0 | $24.05M | $27.19M | 1.10% | +$3.14M |
| Kiniksa Pharmaceuticals International, plcCL A(KNSA) | 587,000 | 521,353 | -65,647 | $24.21M | $25.10M | 1.02% | +$889.4K |
| Merck & Co., Inc.(MRK) | 0 | 203,000 | +203,000 | $0 | $24.42M | 0.99% | +$24.42M |
| Organogenesis Holdings Inc.(ORGO) | 9,985,951 | 10,085,951 | +100,000 | $51.73M | $23.90M | 0.97% | -$27.82M |
| Natera, Inc.(NTRA) | 20,000 | 119,000 | +99,000 | $4.58M | $23.80M | 0.96% | +$19.22M |
| Axogen, Inc.(AXGN) | 1,206,855 | 679,170 | -527,685 | $39.50M | $22.50M | 0.91% | -$17.00M |
| Vaxcyte, Inc.(PCVX) | 608,958 | 385,472 | -223,486 | $28.10M | $22.40M | 0.91% | -$5.70M |
| ICON Public Limited CompanySHS(ICLR) | 0 | 192,000 | +192,000 | $0 | $21.25M | 0.86% | +$21.25M |
| Pharvaris N V COM | 702,052 | 702,052 | 0 | $19.48M | $19.83M | 0.80% | +$351.0K |
| Cerus Corporation(CERS) | 4,000,000 | 10,753,700 | +6,753,700 | $8.24M | $19.57M | 0.79% | +$11.33M |
| Trevi Therapeutics, Inc.(TRVI) | 900,000 | 1,620,000 | +720,000 | $11.27M | $19.33M | 0.78% | +$8.06M |
| Inhibikase Therapeutics, Inc.(IKT) | 10,875,000 | 10,875,000 | 0 | $22.29M | $18.27M | 0.74% | -$4.02M |
| Context Therapeutics Inc.(CNTX) | 0 | 6,963,141 | +6,963,141 | $0 | $18.24M | 0.74% | +$18.24M |
| Vir Biotechnology, Inc.(VIR) | 0 | 2,002,000 | +2,002,000 | $0 | $17.94M | 0.73% | +$17.94M |
| Xenon Pharmaceuticals Inc.(XENE) | 0 | 292,000 | +292,000 | $0 | $16.98M | 0.69% | +$16.98M |
| Travere Therapeutics, Inc.(TVTX) | 0 | 546,000 | +546,000 | $0 | $16.22M | 0.66% | +$16.22M |
| Tandem Diabetes Care, Inc.(TNDM) | 0 | 783,000 | +783,000 | $0 | $15.01M | 0.61% | +$15.01M |
| Nurix Therapeutics, Inc.(NRIX) | 1,219,394 | 938,163 | -281,231 | $23.13M | $14.54M | 0.59% | -$8.59M |
| UroGen Pharma Ltd.(URGN) | 150,000 | 727,000 | +577,000 | $3.51M | $13.07M | 0.53% | +$9.56M |
| Sionna Therapeutics, Inc.(SION) | 268,500 | 293,500 | +25,000 | $11.05M | $11.77M | 0.48% | +$720.3K |
| Corcept Therapeutics Incorporated(CORT) | 0 | 285,531 | +285,531 | $0 | $11.51M | 0.47% | +$11.51M |
| Jade Biosciences Inc | 796,744 | 796,744 | 0 | $12.29M | $11.19M | 0.45% | -$1.10M |
| Veracyte, Inc.(VCYT) | 10,000 | 319,912 | +309,912 | $421.0K | $10.30M | 0.42% | +$9.88M |
| Invivyd, Inc.(IVVD) | 7,708,727 | 7,708,727 | 0 | $19.04M | $10.02M | 0.41% | -$9.02M |
| C4 Therapeutics, Inc.(CCCC) | 3,803,942 | 3,803,942 | 0 | $7.27M | $10.00M | 0.41% | +$2.74M |
| OrthoPediatrics Corp.(KIDS) | 525,447 | 615,447 | +90,000 | $9.33M | $9.77M | 0.40% | +$435.2K |
| Arcus Biosciences, Inc.(RCUS) | 711,983 | 451,983 | -260,000 | $16.97M | $9.76M | 0.40% | -$7.20M |
| Tango Therapeutics, Inc.(TNGX) | 10,000 | 450,000 | +440,000 | $88.6K | $9.41M | 0.38% | +$9.33M |
| Evolus, Inc.(EOLS) | 1,070,000 | 2,245,360 | +1,175,360 | $7.12M | $9.23M | 0.37% | +$2.11M |
| SOPHiA GENETICS SA(SOPH) | 0 | 1,850,000 | +1,850,000 | $0 | $9.16M | 0.37% | +$9.16M |
| Enliven Therapeutics Inc | 1,025,000 | 230,869 | -794,131 | $15.79M | $9.05M | 0.37% | -$6.73M |
| Inhibrx Biosciences, Inc.(INBX) | 25,000 | 131,000 | +106,000 | $1.98M | $8.81M | 0.36% | +$6.83M |
| DexCom, Inc.(DXCM) | 1,297,094 | 140,000 | -1,157,094 | $86.09M | $8.79M | 0.36% | -$77.30M |
| Septerna, Inc.(SEPN) | 383,368 | 275,000 | -108,368 | $10.69M | $6.61M | 0.27% | -$4.08M |
| Avalo Therapeutics, Inc.(AVTX) | 441,978 | 441,978 | 0 | $8.03M | $6.60M | 0.27% | -$1.43M |
| Biodesix, Inc.(BDSX) | 0 | 416,599 | +416,599 | $0 | $6.04M | 0.24% | +$6.04M |
| Relmada Therapeutics, Inc.(RLMD) | 0 | 842,106 | +842,106 | $0 | $5.86M | 0.24% | +$5.86M |
| Cullinan Therapeutics, Inc.(CGEM) | 0 | 410,200 | +410,200 | $0 | $5.83M | 0.24% | +$5.83M |
| Immunovant, Inc.(IMVT) | 1,110,000 | 230,000 | -880,000 | $28.22M | $5.71M | 0.23% | -$22.50M |
| MBX Biosciences, Inc.(MBX) | 408,900 | 178,897 | -230,003 | $12.90M | $5.34M | 0.22% | -$7.56M |
| Immunic, Inc.(IMUX) | 0 | 4,500,000 | +4,500,000 | $0 | $5.00M | 0.20% | +$5.00M |
| Larimar Therapeutics, Inc.(LRMR) | 0 | 1,066,960 | +1,066,960 | $0 | $4.80M | 0.19% | +$4.80M |
| Eton Pharmaceuticals, Inc.(ETON) | 0 | 166,381 | +166,381 | $0 | $4.11M | 0.17% | +$4.11M |
| SAB Biotherapeutics, Inc.(SABS) | 0 | 1,050,000 | +1,050,000 | $0 | $4.02M | 0.16% | +$4.02M |
| PROCEPT BioRobotics Corporation(PRCT) | 0 | 160,000 | +160,000 | $0 | $4.00M | 0.16% | +$4.00M |
| Structure Therapeutics IncADS | 90,000 | 80,000 | -10,000 | $6.26M | $3.86M | 0.16% | -$2.40M |
| Tectonic Therapeutic, Inc.(TECX) | 0 | 121,684 | +121,684 | $0 | $3.76M | 0.15% | +$3.76M |
| Pulmonx Corporation(LUNG) | 2,038,323 | 2,788,323 | +750,000 | $4.50M | $3.60M | 0.15% | -$907.8K |
| Iovance Biotherapeutics, Inc.(IOVA) | 0 | 1,000,000 | +1,000,000 | $0 | $3.51M | 0.14% | +$3.51M |
| argenx SEADR(ARGX) | 31,726 | 3,500 | -28,226 | $26.68M | $2.56M | 0.10% | -$24.12M |
| Karyopharm Therapeutics Inc.(KPTI) | 440,000 | 440,000 | 0 | $3.24M | $2.45M | 0.10% | -$787.6K |
| Satellos Bioscience Inc.(MSLE) | 0 | 414,359 | +414,359 | $0 | $2.33M | 0.09% | +$2.33M |
| Arrowhead Pharmaceuticals, Inc.(ARWR) | 0 | 28,479 | +28,479 | $0 | $1.79M | 0.07% | +$1.79M |
| InspireMD, Inc.(NSPR) | 1,150,000 | 1,045,708 | -104,292 | $2.05M | $1.70M | 0.07% | -$342.5K |
| Insmed Incorporated(INSM) | 48,500 | 10,250 | -38,250 | $8.44M | $1.68M | 0.07% | -$6.76M |
| CytomX Therapeutics, Inc.(CTMX) | 0 | 300,000 | +300,000 | $0 | $1.41M | 0.06% | +$1.41M |
| CG Oncology, Inc.(CGON) | 170,000 | 20,000 | -150,000 | $7.06M | $1.35M | 0.05% | -$5.70M |
| NeoGenomics, Inc.(NEO) | 427,504 | 175,000 | -252,504 | $5.03M | $1.30M | 0.05% | -$3.73M |
| Quoin Pharmaceuticals, Ltd.ADS(QNRX) | 25,000 | 72,730 | +47,730 | $360.8K | $480.0K | 0.02% | +$119.3K |
| Cogent Biosciences, Inc.(COGT) | 120,000 | 10,000 | -110,000 | $4.26M | $384.9K | 0.02% | -$3.88M |
| Tyra Biosciences, Inc.(TYRA) | 125,000 | 10,000 | -115,000 | $3.29M | $383.0K | 0.02% | -$2.90M |
| STAAR Surgical Company(STAA) | 25,000 | 20,000 | -5,000 | $577.3K | $374.0K | 0.02% | -$203.3K |
| Anaptysbio Inc | 135,000 | 6,000 | -129,000 | $6.54M | $332.8K | 0.01% | -$6.21M |
| Rapport Therapeutics, Inc.(RAPP) | 0 | 10,000 | +10,000 | $0 | $312.9K | 0.01% | +$312.9K |
| Rigel Pharmaceuticals, Inc.(RIGL) | 300,034 | 10,000 | -290,034 | $12.85M | $270.4K | 0.01% | -$12.58M |
| Zymeworks Inc.(ZYME) | 100,000 | 10,000 | -90,000 | $2.63M | $250.4K | 0.01% | -$2.38M |
| LB Pharmaceuticals Inc(LBRX) | 10,000 | 10,000 | 0 | $222.6K | $246.6K | 0.01% | +$24.0K |
| Oruka Therapeutics, Inc.(ORKA) | 190,000 | 5,000 | -185,000 | $5.76M | $245.3K | 0.01% | -$5.51M |
| Jasper Therapeutics, Inc.(JSPR) | 200,000 | 276,312 | +76,312 | $366.0K | $242.1K | 0.01% | -$123.9K |
| ABIVAX Société AnonymeADS(ABVX) | 45,000 | 0 | -45,000 | $6.07M | $0 | — | -$6.07M |
| Amicus Therapeutics Inc COM | 5,207,284 | 0 | -5,207,284 | $74.15M | $0 | — | -$74.15M |
| Arcellx Inc COMMON STOCK | 30,000 | 0 | -30,000 | $1.96M | $0 | — | -$1.96M |
| Belite Bio, IncADS(BLTE) | 40,354 | 0 | -40,354 | $6.46M | $0 | — | -$6.46M |
| Bicara Therapeutics Inc | 100,000 | 0 | -100,000 | $1.68M | $0 | — | -$1.68M |
| CalciMedica, Inc.(CALC) | 683,904 | 0 | -683,904 | $4.51M | $0 | — | -$4.51M |
| Capricor Therapeutics, Inc.(CAPR) | 646,390 | 0 | -646,390 | $18.65M | $0 | — | -$18.65M |