Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q1 2025 ▲▼ | Q2 2025 ▲▼ | Change ▲▼ | Q1 2025 ▲▼ | Q2 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Krystal Biotech, Inc.(KRYS) | 441,758 | 922,958 | +481,200 | $79.65M | $126.87M | 8.76% | +$47.22M |
| NovoCure Limited(NVCR) | 5,521,414 | 6,904,302 | +1,382,888 | $98.39M | $122.90M | 8.49% | +$24.50M |
| TG Therapeutics, Inc.(TGTX) | 2,846,703 | 2,243,935 | -602,768 | $112.25M | $80.76M | 5.58% | -$31.49M |
| United Therapeutics Corporation(UTHR) | 155,394 | 209,794 | +54,400 | $47.90M | $60.28M | 4.16% | +$12.38M |
| Beta Bionics, Inc.(BBNX) | 3,395,341 | 3,820,158 | +424,817 | $41.56M | $55.62M | 3.84% | +$14.06M |
| Grifols, S.A.ADR(GRFS) | 7,089,822 | 5,756,805 | -1,333,017 | $50.41M | $52.04M | 3.59% | +$1.63M |
| STAAR Surgical Company(STAA) | 2,562,893 | 2,984,733 | +421,840 | $45.18M | $50.08M | 3.46% | +$4.90M |
| BioMarin Pharmaceutical Inc.(BMRN) | 1,079,304 | 902,304 | -177,000 | $76.30M | $49.60M | 3.43% | -$26.70M |
| Organogenesis Holdings Inc.(ORGO) | 12,478,351 | 12,343,351 | -135,000 | $53.91M | $45.18M | 3.12% | -$8.73M |
| Praxis Precision Medicines, Inc.(PRAX) | 1,139,740 | 966,740 | -173,000 | $43.16M | $40.65M | 2.81% | -$2.51M |
| Celcuity Inc.(CELC) | 2,574,122 | 3,011,818 | +437,696 | $26.02M | $40.21M | 2.78% | +$14.18M |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 0 | 106,750 | +106,750 | $0 | $34.81M | 2.40% | +$34.81M |
| Terns Pharmaceuticals Inc | 8,167,100 | 8,167,100 | 0 | $22.54M | $30.46M | 2.10% | +$7.92M |
| UroGen Pharma Ltd.(URGN) | 0 | 2,185,000 | +2,185,000 | $0 | $29.93M | 2.07% | +$29.93M |
| Nurix Therapeutics, Inc.(NRIX) | 2,422,833 | 2,422,833 | 0 | $28.78M | $27.60M | 1.91% | -$1.19M |
| Elevance Health, Inc.(ELV) | 0 | 70,000 | +70,000 | $0 | $27.23M | 1.88% | +$27.23M |
| UnitedHealth Group Incorporated(UNH) | 0 | 86,250 | +86,250 | $0 | $26.91M | 1.86% | +$26.91M |
| NeuroPace, Inc.(NPCE) | 2,608,168 | 2,312,957 | -295,211 | $32.05M | $25.77M | 1.78% | -$6.29M |
| argenx SEADR(ARGX) | 28,940 | 42,876 | +13,936 | $17.13M | $23.63M | 1.63% | +$6.51M |
| Surmodics Inc | 789,060 | 789,060 | 0 | $24.09M | $23.44M | 1.62% | -$647.0K |
| Geron Corporation(GERN) | 2,400,000 | 16,140,000 | +13,740,000 | $3.82M | $22.76M | 1.57% | +$18.94M |
| Cidara Therapeutics Inc | 0 | 462,811 | +462,811 | $0 | $22.54M | 1.56% | +$22.54M |
| Evolus, Inc.(EOLS) | 1,079,158 | 2,119,000 | +1,039,842 | $12.98M | $19.52M | 1.35% | +$6.53M |
| Humana Inc.(HUM) | 0 | 79,600 | +79,600 | $0 | $19.46M | 1.34% | +$19.46M |
| Veracyte, Inc.(VCYT) | 0 | 715,439 | +715,439 | $0 | $19.34M | 1.34% | +$19.34M |
| Integra LifeSciences Holdings Corporation(IART) | 1,072,204 | 1,387,818 | +315,614 | $23.58M | $17.03M | 1.18% | -$6.55M |
| Axogen, Inc.(AXGN) | 1,446,117 | 1,459,395 | +13,278 | $26.75M | $15.83M | 1.09% | -$10.92M |
| Mirum Pharmaceuticals, Inc.(MIRM) | 0 | 298,696 | +298,696 | $0 | $15.20M | 1.05% | +$15.20M |
| Ascendis Pharma A/SADR(ASND) | 56,300 | 85,000 | +28,700 | $8.77M | $14.67M | 1.01% | +$5.90M |
| Inspire Medical Systems, Inc.(INSP) | 39,000 | 109,000 | +70,000 | $6.21M | $14.14M | 0.98% | +$7.93M |
| Twist Bioscience Corporation(TWST) | 0 | 354,401 | +354,401 | $0 | $13.04M | 0.90% | +$13.04M |
| Pharvaris N V COM | 814,652 | 732,968 | -81,684 | $12.79M | $12.90M | 0.89% | +$110.2K |
| Inhibikase Therapeutics, Inc.(IKT) | 6,325,000 | 6,325,000 | 0 | $13.85M | $12.33M | 0.85% | -$1.52M |
| Rigel Pharmaceuticals, Inc.(RIGL) | 1,130,679 | 658,145 | -472,534 | $20.34M | $12.33M | 0.85% | -$8.01M |
| EDAP TMS S.A.ADR(FOCL) | 7,309,254 | 7,309,254 | 0 | $14.33M | $12.06M | 0.83% | -$2.27M |
| Theratechnologies Inc | 4,801,376 | 4,801,376 | 0 | $6.72M | $11.33M | 0.78% | +$4.61M |
| Syndax Pharmaceuticals, Inc.(SNDX) | 816,610 | 1,092,110 | +275,500 | $10.03M | $10.23M | 0.71% | +$195.6K |
| C4 Therapeutics, Inc.(CCCC) | 6,978,942 | 6,978,942 | 0 | $11.17M | $9.98M | 0.69% | -$1.19M |
| Enovis Corporation(ENOV) | 0 | 315,000 | +315,000 | $0 | $9.88M | 0.68% | +$9.88M |
| Nuvalent Inc | 214,357 | 125,000 | -89,357 | $15.20M | $9.54M | 0.66% | -$5.66M |
| Establishment Labs Holdings Inc.(ESTA) | 0 | 211,900 | +211,900 | $0 | $9.05M | 0.63% | +$9.05M |
| Jasper Therapeutics, Inc.(JSPR) | 1,494,420 | 1,494,420 | 0 | $6.43M | $8.29M | 0.57% | +$1.87M |
| Arcellx Inc COMMON STOCK | 153,031 | 123,031 | -30,000 | $10.04M | $8.10M | 0.56% | -$1.94M |
| Jade Biosciences Inc | 0 | 796,744 | +796,744 | $0 | $7.96M | 0.55% | +$7.96M |
| Insmed Incorporated(INSM) | 274,272 | 72,772 | -201,500 | $20.92M | $7.32M | 0.51% | -$13.60M |
| Anaptysbio Inc | 102,052 | 321,040 | +218,988 | $1.90M | $7.13M | 0.49% | +$5.23M |
| Kiniksa Pharmaceuticals International, plcCL A(KNSA) | 469,500 | 254,689 | -214,811 | $10.43M | $7.05M | 0.49% | -$3.38M |
| Sionna Therapeutics, Inc.(SION) | 240,000 | 376,000 | +136,000 | $2.51M | $6.52M | 0.45% | +$4.01M |
| Crescent Biopharma, Inc.(CBIO) | 0 | 400,000 | +400,000 | $0 | $6.46M | 0.45% | +$6.46M |
| Iovance Biotherapeutics, Inc.(IOVA) | 7,785,000 | 3,261,707 | -4,523,293 | $25.92M | $5.61M | 0.39% | -$20.31M |
| IDEAYA Biosciences, Inc.(IDYA) | 0 | 250,000 | +250,000 | $0 | $5.25M | 0.36% | +$5.25M |
| Immunic, Inc.(IMUX) | 7,293,007 | 7,293,007 | 0 | $7.95M | $5.09M | 0.35% | -$2.86M |
| QuidelOrtho Corporation(QDEL) | 0 | 174,000 | +174,000 | $0 | $5.01M | 0.35% | +$5.01M |
| Scholar Rock Holding Corporation(SRRK) | 285,000 | 125,000 | -160,000 | $9.16M | $4.43M | 0.31% | -$4.74M |
| InspireMD, Inc.(NSPR) | 945,376 | 1,886,207 | +940,831 | $2.54M | $4.28M | 0.30% | +$1.74M |
| Eton Pharmaceuticals, Inc.(ETON) | 0 | 285,000 | +285,000 | $0 | $4.06M | 0.28% | +$4.06M |
| CG Oncology, Inc.(CGON) | 303,585 | 155,000 | -148,585 | $7.43M | $4.03M | 0.28% | -$3.40M |
| Verastem, Inc.(VSTM) | 935,909 | 935,909 | 0 | $5.64M | $3.88M | 0.27% | -$1.76M |
| Essa Pharma Inc | 2,262,026 | 2,262,026 | 0 | $3.57M | $3.85M | 0.27% | +$271.4K |
| Akero Therapeutics Inc | 117,000 | 72,000 | -45,000 | $4.74M | $3.84M | 0.27% | -$894.2K |
| Trevi Therapeutics, Inc.(TRVI) | 0 | 700,000 | +700,000 | $0 | $3.83M | 0.26% | +$3.83M |
| Tango Therapeutics, Inc.(TNGX) | 0 | 730,000 | +730,000 | $0 | $3.74M | 0.26% | +$3.74M |
| Tandem Diabetes Care, Inc.(TNDM) | 496,039 | 200,000 | -296,039 | $9.50M | $3.73M | 0.26% | -$5.78M |
| GeneDx Holdings Corp.CL A(WGS) | 0 | 40,000 | +40,000 | $0 | $3.69M | 0.26% | +$3.69M |
| ANI Pharmaceuticals, Inc.(ANIP) | 224,684 | 50,743 | -173,941 | $15.04M | $3.31M | 0.23% | -$11.73M |
| Mural Oncology Pub Ltd Co | 0 | 1,323,877 | +1,323,877 | $0 | $3.27M | 0.23% | +$3.27M |
| Adma Biologics Inc | 0 | 175,000 | +175,000 | $0 | $3.19M | 0.22% | +$3.19M |
| CytomX Therapeutics, Inc.(CTMX) | 0 | 1,304,300 | +1,304,300 | $0 | $2.96M | 0.20% | +$2.96M |
| Orthofix Medical Inc.(OFIX) | 601,925 | 261,147 | -340,778 | $9.82M | $2.91M | 0.20% | -$6.91M |
| Erasca, Inc.(ERAS) | 2,162,162 | 2,162,162 | 0 | $2.96M | $2.75M | 0.19% | -$216.2K |
| Denali Therapeutics Inc.(DNLI) | 135,000 | 182,110 | +47,110 | $1.84M | $2.55M | 0.18% | +$712.4K |
| Xenon Pharmaceuticals Inc.(XENE) | 0 | 78,800 | +78,800 | $0 | $2.47M | 0.17% | +$2.47M |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 67,500 | 8,000 | -59,500 | $22.36M | $2.42M | 0.17% | -$19.94M |
| Vericel Corporation(VCEL) | 0 | 50,953 | +50,953 | $0 | $2.17M | 0.15% | +$2.17M |
| Merus N V | 385,821 | 40,000 | -345,821 | $16.24M | $2.10M | 0.15% | -$14.14M |
| SkinHealth Systems Inc.CL A(SKIN) | 0 | 1,000,000 | +1,000,000 | $0 | $1.91M | 0.13% | +$1.91M |
| Mereo BioPharma Group plcADS(MREO) | 686,953 | 599,711 | -87,242 | $1.55M | $1.63M | 0.11% | +$79.6K |
| Y-Mabs Therapeutics Inc | 349,982 | 349,982 | 0 | $1.55M | $1.58M | 0.11% | +$28.0K |
| Tectonic Therapeutic, Inc.(TECX) | 76,841 | 76,841 | 0 | $1.36M | $1.53M | 0.11% | +$166.0K |
| Myomo, Inc.(MYO) | 704,275 | 704,275 | 0 | $3.39M | $1.52M | 0.11% | -$1.87M |
| CalciMedica, Inc.(CALC) | 783,904 | 783,904 | 0 | $1.50M | $1.25M | 0.09% | -$243.0K |
| Edgewise Therapeutics, Inc.(EWTX) | 72,300 | 76,493 | +4,193 | $1.59M | $1.00M | 0.07% | -$587.8K |
| OrthoPediatrics Corp.(KIDS) | 45,000 | 45,000 | 0 | $1.11M | $966.6K | 0.07% | -$141.8K |
| ABIVAX Société AnonymeADS(ABVX) | 125,000 | 125,000 | 0 | $781.3K | $956.3K | 0.07% | +$175.0K |
| CeriBell, Inc.(CBLL) | 0 | 50,000 | +50,000 | $0 | $936.5K | 0.06% | +$936.5K |
| Soleno Therapeutics Inc | 150,000 | 10,000 | -140,000 | $10.72M | $837.8K | 0.06% | -$9.88M |
| Septerna, Inc.(SEPN) | 751,353 | 75,456 | -675,897 | $4.35M | $797.6K | 0.06% | -$3.55M |
| Bicycle Therapeutics PlcADS | 0 | 100,000 | +100,000 | $0 | $695.0K | 0.05% | +$695.0K |
| Adverum Biotechnologies Inc | 287,246 | 287,246 | 0 | $1.26M | $617.6K | 0.04% | -$637.7K |
| Revolution Medicines, Inc.(RVMD) | 84,784 | 10,000 | -74,784 | $3.00M | $367.9K | 0.03% | -$2.63M |
| Delcath Systems, Inc.(DCTH) | 232,722 | 25,000 | -207,722 | $2.96M | $340.0K | 0.02% | -$2.62M |
| Io Biotech Inc | 192,670 | 192,670 | 0 | $210.0K | $267.8K | 0.02% | +$57.8K |
| Axsome Therapeutics, Inc.(AXSM) | 17,000 | 2,000 | -15,000 | $1.98M | $208.8K | 0.01% | -$1.77M |
| Adaptive Biotechnologies Corporation(ADPT) | 10,000 | 10,000 | 0 | $74.3K | $116.5K | 0.01% | +$42.2K |
| Apogee Therapeutics Inc | 16,000 | 0 | -16,000 | $597.8K | $0 | — | -$597.8K |
| Hologic Inc | 302,000 | 0 | -302,000 | $18.65M | $0 | — | -$18.65M |
| LivaNova PLCSHS(LIVN) | 117,040 | 0 | -117,040 | $4.60M | $0 | — | -$4.60M |
| Protagonist Therapeutics Inc | 169,000 | 0 | -169,000 | $8.17M | $0 | — | -$8.17M |
| SanofiADR(SNY) | 226,218 | 0 | -226,218 | $12.55M | $0 | — | -$12.55M |
| Sarepta Therapeutics, Inc.(SRPT) | 58,000 | 0 | -58,000 | $3.70M | $0 | — | -$3.70M |