Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q2 2025 ▲▼ | Q3 2025 ▲▼ | Change ▲▼ | Q2 2025 ▲▼ | Q3 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Krystal Biotech, Inc.(KRYS) | 922,958 | 1,018,831 | +95,873 | $126.87M | $179.85M | 9.61% | +$52.98M |
| TG Therapeutics, Inc.(TGTX) | 2,243,935 | 3,844,731 | +1,600,796 | $80.76M | $138.89M | 7.42% | +$58.13M |
| NovoCure Limited(NVCR) | 6,904,302 | 9,644,872 | +2,740,570 | $122.90M | $124.61M | 6.66% | +$1.72M |
| Elevance Health, Inc.(ELV) | 70,000 | 259,650 | +189,650 | $27.23M | $83.90M | 4.48% | +$56.67M |
| Beta Bionics, Inc.(BBNX) | 3,820,158 | 3,870,158 | +50,000 | $55.62M | $76.90M | 4.11% | +$21.28M |
| United Therapeutics Corporation(UTHR) | 209,794 | 150,000 | -59,794 | $60.28M | $62.88M | 3.36% | +$2.60M |
| Terns Pharmaceuticals Inc | 8,167,100 | 8,127,100 | -40,000 | $30.46M | $61.03M | 3.26% | +$30.57M |
| Celcuity Inc.(CELC) | 3,011,818 | 1,178,860 | -1,832,958 | $40.21M | $58.24M | 3.11% | +$18.03M |
| Inspire Medical Systems, Inc.(INSP) | 109,000 | 728,188 | +619,188 | $14.14M | $54.03M | 2.89% | +$39.89M |
| Twist Bioscience Corporation(TWST) | 354,401 | 1,866,234 | +1,511,833 | $13.04M | $52.52M | 2.81% | +$39.48M |
| argenx SEADR(ARGX) | 42,876 | 69,426 | +26,550 | $23.63M | $51.21M | 2.74% | +$27.57M |
| Organogenesis Holdings Inc.(ORGO) | 12,343,351 | 12,131,699 | -211,652 | $45.18M | $51.20M | 2.74% | +$6.02M |
| BioMarin Pharmaceutical Inc.(BMRN) | 902,304 | 890,304 | -12,000 | $49.60M | $48.22M | 2.58% | -$1.38M |
| Cidara Therapeutics Inc | 462,811 | 493,811 | +31,000 | $22.54M | $47.29M | 2.53% | +$24.74M |
| Praxis Precision Medicines, Inc.(PRAX) | 966,740 | 859,166 | -107,574 | $40.65M | $45.54M | 2.43% | +$4.88M |
| Amicus Therapeutics Inc COM | 0 | 4,690,000 | +4,690,000 | $0 | $36.96M | 1.98% | +$36.96M |
| Indivior Plc | 0 | 1,466,000 | +1,466,000 | $0 | $35.35M | 1.89% | +$35.35M |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 8,000 | 68,336 | +60,336 | $2.42M | $31.34M | 1.68% | +$28.92M |
| ANI Pharmaceuticals, Inc.(ANIP) | 50,743 | 340,243 | +289,500 | $3.31M | $31.17M | 1.67% | +$27.86M |
| Syndax Pharmaceuticals, Inc.(SNDX) | 1,092,110 | 2,012,110 | +920,000 | $10.23M | $30.96M | 1.65% | +$20.73M |
| Axogen, Inc.(AXGN) | 1,459,395 | 1,726,553 | +267,158 | $15.83M | $30.80M | 1.65% | +$14.97M |
| NeuroPace, Inc.(NPCE) | 2,312,957 | 2,957,957 | +645,000 | $25.77M | $30.50M | 1.63% | +$4.73M |
| Grifols, S.A.ADR(GRFS) | 5,756,805 | 2,500,000 | -3,256,805 | $52.04M | $24.90M | 1.33% | -$27.14M |
| Geron Corporation(GERN) | 16,140,000 | 17,290,000 | +1,150,000 | $22.76M | $23.69M | 1.27% | +$929.9K |
| Nurix Therapeutics, Inc.(NRIX) | 2,422,833 | 2,422,833 | 0 | $27.60M | $22.39M | 1.20% | -$5.21M |
| Integra LifeSciences Holdings Corporation(IART) | 1,387,818 | 1,440,818 | +53,000 | $17.03M | $20.65M | 1.10% | +$3.62M |
| Neurocrine Biosciences, Inc.(NBIX) | 0 | 138,000 | +138,000 | $0 | $19.37M | 1.04% | +$19.37M |
| Anaptysbio Inc | 321,040 | 626,040 | +305,000 | $7.13M | $19.17M | 1.02% | +$12.04M |
| EDAP TMS S.A.ADR(FOCL) | 7,309,254 | 7,309,254 | 0 | $12.06M | $16.74M | 0.89% | +$4.68M |
| Pharvaris N V COM | 732,968 | 647,052 | -85,916 | $12.90M | $16.14M | 0.86% | +$3.24M |
| Vericel Corporation(VCEL) | 50,953 | 497,953 | +447,000 | $2.17M | $15.67M | 0.84% | +$13.50M |
| C4 Therapeutics, Inc.(CCCC) | 6,978,942 | 7,053,942 | +75,000 | $9.98M | $15.66M | 0.84% | +$5.68M |
| Belite Bio, IncADS(BLTE) | 0 | 210,000 | +210,000 | $0 | $15.54M | 0.83% | +$15.54M |
| Veracyte, Inc.(VCYT) | 715,439 | 422,055 | -293,384 | $19.34M | $14.49M | 0.77% | -$4.85M |
| Rapt Therapeutics Inc | 0 | 537,903 | +537,903 | $0 | $13.87M | 0.74% | +$13.87M |
| UroGen Pharma Ltd.(URGN) | 2,185,000 | 679,000 | -1,506,000 | $29.93M | $13.55M | 0.72% | -$16.39M |
| STAAR Surgical Company(STAA) | 2,984,733 | 500,000 | -2,484,733 | $50.08M | $13.44M | 0.72% | -$36.65M |
| Sionna Therapeutics, Inc.(SION) | 376,000 | 413,500 | +37,500 | $6.52M | $12.16M | 0.65% | +$5.64M |
| CG Oncology, Inc.(CGON) | 155,000 | 290,000 | +135,000 | $4.03M | $11.68M | 0.62% | +$7.65M |
| uniQure N.V.SHS(QURE) | 0 | 200,000 | +200,000 | $0 | $11.67M | 0.62% | +$11.67M |
| QuidelOrtho Corporation(QDEL) | 174,000 | 375,000 | +201,000 | $5.01M | $11.04M | 0.59% | +$6.03M |
| Mirum Pharmaceuticals, Inc.(MIRM) | 298,696 | 148,696 | -150,000 | $15.20M | $10.90M | 0.58% | -$4.30M |
| Adma Biologics Inc | 175,000 | 738,000 | +563,000 | $3.19M | $10.82M | 0.58% | +$7.63M |
| Inhibikase Therapeutics, Inc.(IKT) | 6,325,000 | 6,325,000 | 0 | $12.33M | $10.25M | 0.55% | -$2.09M |
| Globus Medical, Inc.CL A(GMED) | 0 | 176,000 | +176,000 | $0 | $10.08M | 0.54% | +$10.08M |
| GSK plcADR(GSK) | 0 | 220,000 | +220,000 | $0 | $9.50M | 0.51% | +$9.50M |
| Rigel Pharmaceuticals, Inc.(RIGL) | 658,145 | 330,010 | -328,135 | $12.33M | $9.35M | 0.50% | -$2.98M |
| Evolus, Inc.(EOLS) | 2,119,000 | 1,450,000 | -669,000 | $19.52M | $8.90M | 0.48% | -$10.61M |
| Verastem, Inc.(VSTM) | 935,909 | 935,909 | 0 | $3.88M | $8.26M | 0.44% | +$4.38M |
| Arcellx Inc COMMON STOCK | 123,031 | 100,000 | -23,031 | $8.10M | $8.21M | 0.44% | +$108.4K |
| Nuvalent Inc | 125,000 | 88,000 | -37,000 | $9.54M | $7.61M | 0.41% | -$1.93M |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 106,750 | 15,250 | -91,500 | $34.81M | $6.95M | 0.37% | -$27.86M |
| Jade Biosciences Inc | 796,744 | 796,744 | 0 | $7.96M | $6.88M | 0.37% | -$1.08M |
| LB Pharmaceuticals Inc(LBRX) | 0 | 400,000 | +400,000 | $0 | $6.32M | 0.34% | +$6.32M |
| Olema Pharmaceuticals, Inc.(OLMA) | 0 | 619,874 | +619,874 | $0 | $6.07M | 0.32% | +$6.07M |
| Kiniksa Pharmaceuticals International, plcCL A(KNSA) | 254,689 | 150,000 | -104,689 | $7.05M | $5.82M | 0.31% | -$1.22M |
| Establishment Labs Holdings Inc.(ESTA) | 211,900 | 139,512 | -72,388 | $9.05M | $5.72M | 0.31% | -$3.33M |
| MBX Biosciences, Inc.(MBX) | 0 | 275,000 | +275,000 | $0 | $4.81M | 0.26% | +$4.81M |
| Erasca, Inc.(ERAS) | 2,162,162 | 2,162,162 | 0 | $2.75M | $4.71M | 0.25% | +$1.97M |
| Eton Pharmaceuticals, Inc.(ETON) | 285,000 | 200,000 | -85,000 | $4.06M | $4.35M | 0.23% | +$284.8K |
| CeriBell, Inc.(CBLL) | 50,000 | 360,000 | +310,000 | $936.5K | $4.14M | 0.22% | +$3.20M |
| Harrow, Inc.(HROW) | 0 | 85,498 | +85,498 | $0 | $4.12M | 0.22% | +$4.12M |
| Fractyl Health, Inc.(GUTS) | 0 | 2,500,000 | +2,500,000 | $0 | $3.98M | 0.21% | +$3.98M |
| Jasper Therapeutics, Inc.(JSPR) | 1,494,420 | 1,494,420 | 0 | $8.29M | $3.56M | 0.19% | -$4.74M |
| InspireMD, Inc.(NSPR) | 1,886,207 | 1,470,934 | -415,273 | $4.28M | $3.54M | 0.19% | -$736.7K |
| Akero Therapeutics Inc | 72,000 | 71,000 | -1,000 | $3.84M | $3.37M | 0.18% | -$470.8K |
| IDEAYA Biosciences, Inc.(IDYA) | 250,000 | 100,000 | -150,000 | $5.25M | $2.72M | 0.15% | -$2.53M |
| Tango Therapeutics, Inc.(TNGX) | 730,000 | 300,000 | -430,000 | $3.74M | $2.52M | 0.13% | -$1.22M |
| Crescent Biopharma, Inc.(CBIO) | 400,000 | 200,000 | -200,000 | $6.46M | $2.38M | 0.13% | -$4.08M |
| Rapport Therapeutics, Inc.(RAPP) | 0 | 80,000 | +80,000 | $0 | $2.38M | 0.13% | +$2.38M |
| OrthoPediatrics Corp.(KIDS) | 45,000 | 128,000 | +83,000 | $966.6K | $2.37M | 0.13% | +$1.41M |
| Iovance Biotherapeutics, Inc.(IOVA) | 3,261,707 | 976,707 | -2,285,000 | $5.61M | $2.12M | 0.11% | -$3.49M |
| CalciMedica, Inc.(CALC) | 783,904 | 683,904 | -100,000 | $1.25M | $2.10M | 0.11% | +$849.3K |
| Vistagen Therapeutics, Inc.(VTGN) | 0 | 550,000 | +550,000 | $0 | $1.95M | 0.10% | +$1.95M |
| MannKind Corporation(MNKD) | 0 | 300,000 | +300,000 | $0 | $1.61M | 0.09% | +$1.61M |
| Immunic, Inc.(IMUX) | 7,293,007 | 1,580,007 | -5,713,000 | $5.09M | $1.39M | 0.07% | -$3.69M |
| Adverum Biotechnologies Inc | 287,246 | 287,246 | 0 | $617.6K | $1.30M | 0.07% | +$683.6K |
| Liquidia Corporation(LQDA) | 0 | 50,000 | +50,000 | $0 | $1.14M | 0.06% | +$1.14M |
| Essa Pharma Inc | 2,262,026 | 4,362,026 | +2,100,000 | $3.85M | $833.1K | 0.04% | -$3.01M |
| Myomo, Inc.(MYO) | 704,275 | 704,275 | 0 | $1.52M | $628.2K | 0.03% | -$893.0K |
| Mereo BioPharma Group plcADS(MREO) | 599,711 | 299,711 | -300,000 | $1.63M | $617.4K | 0.03% | -$1.01M |
| Tectonic Therapeutic, Inc.(TECX) | 76,841 | 25,000 | -51,841 | $1.53M | $392.3K | 0.02% | -$1.13M |
| Insmed Incorporated(INSM) | 72,772 | 2,550 | -70,222 | $7.32M | $367.2K | 0.02% | -$6.96M |
| Septerna, Inc.(SEPN) | 75,456 | 18,260 | -57,196 | $797.6K | $343.5K | 0.02% | -$454.1K |
| Kodiak Sciences Inc.(KOD) | 0 | 19,644 | +19,644 | $0 | $321.6K | 0.02% | +$321.6K |
| Trevi Therapeutics, Inc.(TRVI) | 700,000 | 25,000 | -675,000 | $3.83M | $228.8K | 0.01% | -$3.60M |
| Delcath Systems, Inc.(DCTH) | 25,000 | 10,000 | -15,000 | $340.0K | $107.5K | 0.01% | -$232.5K |
| ABIVAX Société AnonymeADS(ABVX) | 125,000 | 0 | -125,000 | $956.3K | $0 | — | -$956.3K |
| Adaptive Biotechnologies Corporation(ADPT) | 10,000 | 0 | -10,000 | $116.5K | $0 | — | -$116.5K |
| Ascendis Pharma A/SADR(ASND) | 85,000 | 0 | -85,000 | $14.67M | $0 | — | -$14.67M |
| Axsome Therapeutics, Inc.(AXSM) | 2,000 | 0 | -2,000 | $208.8K | $0 | — | -$208.8K |
| Bicycle Therapeutics PlcADS | 100,000 | 0 | -100,000 | $695.0K | $0 | — | -$695.0K |
| CytomX Therapeutics, Inc.(CTMX) | 1,304,300 | 0 | -1,304,300 | $2.96M | $0 | — | -$2.96M |
| Denali Therapeutics Inc.(DNLI) | 182,110 | 0 | -182,110 | $2.55M | $0 | — | -$2.55M |
| Edgewise Therapeutics, Inc.(EWTX) | 76,493 | 0 | -76,493 | $1.00M | $0 | — | -$1.00M |
| Enovis Corporation(ENOV) | 315,000 | 0 | -315,000 | $9.88M | $0 | — | -$9.88M |
| GeneDx Holdings Corp.CL A(WGS) | 40,000 | 0 | -40,000 | $3.69M | $0 | — | -$3.69M |
| Humana Inc.(HUM) | 79,600 | 0 | -79,600 | $19.46M | $0 | — | -$19.46M |
| Io Biotech Inc | 192,670 | 0 | -192,670 | $267.8K | $0 | — | -$267.8K |
| Merus N V | 40,000 | 0 | -40,000 | $2.10M | $0 | — | -$2.10M |