Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q3 2024 ▲▼ | Q4 2024 ▲▼ | Change ▲▼ | Q3 2024 ▲▼ | Q4 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| NOVOCURE LTD(NVCR) | 0 | 2,739,704 | +2,739,704 | 0 | 81,643 | 6.18% | +81,643 |
| BIOMARIN PHARMACEUTICAL INC(BMRN) | 0 | 1,001,400 | +1,001,400 | 0 | 65,822 | 4.98% | +65,822 |
| TEVA PHARMACEUTICAL INDS LTD(TEVA) | 0 | 2,093,000 | +2,093,000 | 0 | 46,130 | 3.49% | +46,130 |
| INTEGRA LIFESCIENCES HLDGS C(IART) | 0 | 1,276,000 | +1,276,000 | 0 | 28,940 | 2.19% | +28,940 |
| ASTRAZENECA PLC(AZN) | 0 | 409,000 | +409,000 | 0 | 26,798 | 2.03% | +26,798 |
| TG THERAPEUTICS INC(TGTX) | 2,534,540 | 2,681,242 | +146,702 | 59,283 | 80,705 | 6.11% | +21,422 |
| INHIBIKASE THERAPEUTICS INC(IKT) | 0 | 6,325,000 | +6,325,000 | 0 | 20,556 | 1.56% | +20,556 |
| INSMED INC(INSM) | 30,272 | 320,272 | +290,000 | 2,210 | 22,112 | 1.67% | +19,902 |
| ASCENDIS PHARMA A/S(ASND) | 0 | 144,000 | +144,000 | 0 | 19,824 | 1.50% | +19,824 |
| KRYSTAL BIOTECH INC(KRYS) | 216,979 | 358,379 | +141,400 | 39,497 | 56,144 | 4.25% | +16,647 |
| NURIX THERAPEUTICS INC(NRIX) | 1,065,834 | 2,102,833 | +1,036,999 | 23,949 | 39,617 | 3.00% | +15,668 |
| SEPTERNA INC(SEPN) | 0 | 675,409 | +675,409 | 0 | 15,467 | 1.17% | +15,467 |
| CELCUITY INC(CELC) | 1,245,387 | 2,565,087 | +1,319,700 | 18,569 | 33,577 | 2.54% | +15,008 |
| ADAPTIVE BIOTECHNOLOGIES COR(ADPT) | 1,112,749 | 2,983,142 | +1,870,393 | 5,697 | 17,884 | 1.35% | +12,187 |
| SYNDAX PHARMACEUTICALS INC(SNDX) | 1,090,984 | 2,492,000 | +1,401,016 | 21,001 | 32,944 | 2.49% | +11,943 |
| PROTAGONIST THERAPEUTICS INC | 0 | 275,000 | +275,000 | 0 | 10,615 | 0.80% | +10,615 |
| NEUROPACE INC(NPCE) | 2,433,168 | 2,433,168 | 0 | 16,959 | 27,227 | 2.06% | +10,268 |
| DELCATH SYS INC(DCTH) | 0 | 801,000 | +801,000 | 0 | 9,644 | 0.73% | +9,644 |
| GRIFOLS S A(GRFS) | 4,521,703 | 6,605,425 | +2,083,722 | 40,153 | 49,144 | 3.72% | +8,992 |
| TAKEDA PHARMACEUTICAL CO LTD(TAK) | 500,000 | 1,180,000 | +680,000 | 7,110 | 15,623 | 1.18% | +8,513 |
| SCHOLAR ROCK HLDG CORP(SRRK) | 0 | 167,543 | +167,543 | 0 | 7,241 | 0.55% | +7,241 |
| JASPER THERAPEUTICS INC(JSPR) | 1,343,665 | 1,494,420 | +150,755 | 25,274 | 31,951 | 2.42% | +6,676 |
| AXOGEN INC(AXGN) | 3,005,943 | 2,955,943 | -50,000 | 42,143 | 48,714 | 3.69% | +6,571 |
| ORGANOGENESIS HLDGS INC(ORGO) | 11,839,876 | 12,484,876 | +645,000 | 33,862 | 39,952 | 3.02% | +6,090 |
| MYOMO INC(MYO) | 0 | 900,000 | +900,000 | 0 | 5,796 | 0.44% | +5,796 |
| ANAPTYSBIO INC | 0 | 414,000 | +414,000 | 0 | 5,481 | 0.41% | +5,481 |
| VAXCYTE INC(PCVX) | 27,050 | 99,050 | +72,000 | 3,091 | 8,108 | 0.61% | +5,017 |
| EDGEWISE THERAPEUTICS INC(EWTX) | 0 | 183,300 | +183,300 | 0 | 4,894 | 0.37% | +4,894 |
| PHARVARIS N V COM | 598,169 | 814,652 | +216,483 | 11,078 | 15,617 | 1.18% | +4,539 |
| VERICEL CORP(VCEL) | 0 | 80,696 | +80,696 | 0 | 4,431 | 0.34% | +4,431 |
| CRINETICS PHARMACEUTICALS IN(CRNX) | 0 | 85,000 | +85,000 | 0 | 4,346 | 0.33% | +4,346 |
| RIGEL PHARMACEUTICALS INC(RIGL) | 934,788 | 1,130,679 | +195,891 | 15,125 | 19,018 | 1.44% | +3,893 |
| PRAXIS PRECISION MEDICINES I(PRAX) | 259,398 | 243,540 | -15,858 | 14,926 | 18,743 | 1.42% | +3,817 |
| ROCKET PHARMACEUTICALS INC(RCKT) | 0 | 271,659 | +271,659 | 0 | 3,415 | 0.26% | +3,415 |
| MADRIGAL PHARMACEUTICALS INC(MDGL) | 0 | 10,900 | +10,900 | 0 | 3,363 | 0.25% | +3,363 |
| REPLIMUNE GROUP INC(REPL) | 0 | 262,500 | +262,500 | 0 | 3,179 | 0.24% | +3,179 |
| APOGEE THERAPEUTICS INC(APGE) | 0 | 70,000 | +70,000 | 0 | 3,171 | 0.24% | +3,171 |
| VERASTEM INC(VSTM) | 2,827,963 | 2,184,026 | -643,937 | 8,456 | 11,291 | 0.85% | +2,836 |
| THERATECHNOLOGIES INC | 4,801,376 | 4,801,376 | 0 | 5,954 | 8,690 | 0.66% | +2,737 |
| ORTHOFIX MED INC(OFIX) | 606,933 | 686,374 | +79,441 | 9,480 | 11,984 | 0.91% | +2,504 |
| UNITED THERAPEUTICS CORP DEL(UTHR) | 101,894 | 109,394 | +7,500 | 36,514 | 38,599 | 2.92% | +2,085 |
| ALNYLAM PHARMACEUTICALS INC(ALNY) | 59,400 | 76,800 | +17,400 | 16,337 | 18,072 | 1.37% | +1,735 |
| REGENERON PHARMACEUTICALS(REGN) | 0 | 2,300 | +2,300 | 0 | 1,638 | 0.12% | +1,638 |
| ARCELLX INC COMMON STOCK | 93,031 | 121,031 | +28,000 | 7,769 | 9,282 | 0.70% | +1,513 |
| TECTONIC THERAPEUTIC INC(TECX) | 0 | 31,841 | +31,841 | 0 | 1,470 | 0.11% | +1,470 |
| NUVALENT INC | 74,357 | 104,357 | +30,000 | 7,607 | 8,169 | 0.62% | +562 |
| AADI BIOSCIENCE INC(WHWK) | 333,227 | 333,227 | 0 | 686 | 1,051 | 0.08% | +365 |
| GENEDX HOLDINGS CORP(WGS) | 0 | 4,000 | +4,000 | 0 | 307 | 0.02% | +307 |
| TENET HEALTHCARE CORP(THC) | 0 | 2,027 | +2,027 | 0 | 256 | 0.02% | +256 |
| ESTABLISHMENT LABS HLDGS INC(ESTA) | 59,400 | 59,400 | 0 | 2,570 | 2,737 | 0.21% | +166 |
| IO BIOTECH INC(IOBTQ) | 192,670 | 192,670 | 0 | 202 | 177 | 0.01% | -25 |
| INSPIREMD INC(NSPR) | 1,378,128 | 1,378,128 | 0 | 3,693 | 3,624 | 0.27% | -69 |
| IMMUNOVANT INC(IMVT) | 9,678 | 0 | -9,678 | 276 | 0 | — | -276 |
| MDXHEALTH SA(MDXH) | 1,105,000 | 851,688 | -253,312 | 2,298 | 2,019 | 0.15% | -280 |
| ERASCA INC(ERAS) | 2,162,162 | 2,162,162 | 0 | 5,903 | 5,427 | 0.41% | -476 |
| ABIVAX SA(ABVX) | 125,000 | 125,000 | 0 | 1,440 | 915 | 0.07% | -525 |
| ADVERUM BIOTECHNOLOGIES INC | 287,246 | 287,246 | 0 | 2,016 | 1,341 | 0.10% | -675 |
| CALCIMEDICA INC(CALC) | 783,904 | 783,904 | 0 | 3,473 | 2,775 | 0.21% | -698 |
| MEREO BIOPHARMA GROUP PLC(MREO) | 846,953 | 786,953 | -60,000 | 3,481 | 2,754 | 0.21% | -727 |
| GSK PLC(GSK) | 37,500 | 10,110 | -27,390 | 1,533 | 342 | 0.03% | -1,191 |
| OLEMA PHARMACEUTICALS INC(OLMA) | 103,500 | 0 | -103,500 | 1,236 | 0 | — | -1,236 |
| VIRIDIAN THERAPEUTICS INC(VRDN) | 95,000 | 45,500 | -49,500 | 2,161 | 872 | 0.07% | -1,289 |
| BICYCLE THERAPEUTICS PLC | 78,315 | 0 | -78,315 | 1,772 | 0 | — | -1,772 |
| VERACYTE INC(VCYT) | 54,303 | 0 | -54,303 | 1,848 | 0 | — | -1,848 |
| CERVOMED INC(CRVO) | 126,614 | 0 | -126,614 | 1,849 | 0 | — | -1,849 |
| EDAP TMS S A(FOCL) | 7,309,254 | 7,309,254 | 0 | 18,639 | 16,153 | 1.22% | -2,485 |
| Y-MABS THERAPEUTICS INC | 399,982 | 349,982 | -50,000 | 5,260 | 2,740 | 0.21% | -2,519 |
| TANGO THERAPEUTICS INC(TNGX) | 343,152 | 0 | -343,152 | 2,642 | 0 | — | -2,642 |
| ABBVIE INC(ABBV) | 15,750 | 0 | -15,750 | 3,110 | 0 | — | -3,110 |
| CG ONCOLOGY INC(CGON) | 340,585 | 328,585 | -12,000 | 12,850 | 9,424 | 0.71% | -3,426 |
| NATERA INC(NTRA) | 29,900 | 0 | -29,900 | 3,796 | 0 | — | -3,796 |
| BAUSCH PLUS LOMB CORP | 312,000 | 120,500 | -191,500 | 6,018 | 2,176 | 0.16% | -3,842 |
| INARI MED INC | 93,878 | 0 | -93,878 | 3,872 | 0 | — | -3,872 |
| INSULET CORP(PODD) | 16,750 | 0 | -16,750 | 3,899 | 0 | — | -3,899 |
| DYNE THERAPEUTICS INC(DYN) | 117,500 | 0 | -117,500 | 4,221 | 0 | — | -4,221 |
| ENLIVEN THERAPEUTICS INC | 239,705 | 75,405 | -164,300 | 6,122 | 1,697 | 0.13% | -4,425 |
| BIOATLA INC(BCAB) | 2,517,478 | 0 | -2,517,478 | 4,431 | 0 | — | -4,431 |
| ANI PHARMACEUTICALS INC(ANIP) | 269,000 | 205,294 | -63,706 | 16,049 | 11,349 | 0.86% | -4,700 |
| SILENCE THERAPEUTICS PLC(SLN) | 260,000 | 0 | -260,000 | 4,727 | 0 | — | -4,727 |
| IMMUNIC INC(IMUX) | 7,293,007 | 7,293,007 | 0 | 12,033 | 7,293 | 0.55% | -4,740 |
| TREACE MED CONCEPTS INC(TMCI) | 887,941 | 0 | -887,941 | 5,150 | 0 | — | -5,150 |
| ENGENE HOLDINGS INC COM | 800,000 | 0 | -800,000 | 5,280 | 0 | — | -5,280 |
| ALECTOR INC | 1,207,371 | 0 | -1,207,371 | 5,626 | 0 | — | -5,626 |
| ARVINAS INC(ARVN) | 228,800 | 0 | -228,800 | 5,635 | 0 | — | -5,635 |
| APPLIED THERAPEUTICS INC | 680,784 | 0 | -680,784 | 5,787 | 0 | — | -5,787 |
| SUMMIT THERAPEUTICS INC(SMMT) | 285,000 | 0 | -285,000 | 6,242 | 0 | — | -6,241 |
| RELAY THERAPEUTICS INC(RLAY) | 910,000 | 0 | -910,000 | 6,443 | 0 | — | -6,443 |
| MERUS N V | 398,321 | 312,321 | -86,000 | 19,900 | 13,133 | 0.99% | -6,767 |
| TERNS PHARMACEUTICALS INC | 6,223,544 | 8,142,500 | +1,918,956 | 51,904 | 45,109 | 3.41% | -6,795 |
| QUIDELORTHO CORP(QDEL) | 686,000 | 547,082 | -138,918 | 31,282 | 24,373 | 1.84% | -6,909 |
| BIODESIX INC(BDSX) | 4,038,065 | 0 | -4,038,065 | 7,188 | 0 | — | -7,188 |
| KINIKSA PHARMACEUTICALS INTL(KNSA) | 302,500 | 0 | -302,500 | 7,559 | 0 | — | -7,559 |
| ORTHOPEDIATRICS CORP(KIDS) | 288,945 | 0 | -288,945 | 7,833 | 0 | — | -7,833 |
| ELI LILLY & CO(LLY) | 19,300 | 11,658 | -7,642 | 17,099 | 9,000 | 0.68% | -8,099 |
| ENANTA PHARMACEUTICALS INC(ENTA) | 785,546 | 0 | -785,546 | 8,138 | 0 | — | -8,138 |
| EVOLUS INC(EOLS) | 1,037,680 | 697,158 | -340,522 | 16,810 | 7,697 | 0.58% | -9,114 |
| SURMODICS INC | 637,698 | 394,060 | -243,638 | 24,730 | 15,605 | 1.18% | -9,125 |
| LONGBOARD PHARMACEUTICALS IN | 318,269 | 0 | -318,269 | 10,608 | 0 | — | -10,608 |
| BAUSCH HEALTH COS INC | 1,424,000 | 0 | -1,424,000 | 11,620 | 0 | — | -11,620 |
| CASTLE BIOSCIENCES INC(CSTL) | 662,332 | 252,917 | -409,415 | 18,890 | 6,740 | 0.51% | -12,149 |