Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Kalvista Pharmaceuticals Inc | 2,427,118 | 2,876,407 | +449,289 | $39.20M | $57.90M | 6.82% | +$18.70M |
| Dianthus Therapeutics, Inc.(DNTH) | 750,136 | 654,746 | -95,390 | $30.91M | $54.95M | 6.47% | +$24.03M |
| Cogent Biosciences, Inc.(COGT) | 1,245,254 | 1,314,189 | +68,935 | $44.23M | $50.58M | 5.96% | +$6.35M |
| Celcuity Inc.(CELC) | 375,132 | 357,903 | -17,229 | $37.42M | $40.85M | 4.81% | +$3.44M |
| Immunome, Inc.(IMNM) | 1,126,210 | 1,850,278 | +724,068 | $24.19M | $40.47M | 4.77% | +$16.27M |
| Kodiak Sciences Inc.(KOD) | 1,023,122 | 991,930 | -31,192 | $28.61M | $37.81M | 4.46% | +$9.21M |
| Nuvalent Inc | 311,430 | 354,914 | +43,484 | $31.33M | $36.36M | 4.28% | +$5.03M |
| ABIVAX Société AnonymeADS(ABVX) | 422,193 | 302,530 | -119,663 | $56.93M | $33.69M | 3.97% | -$23.25M |
| Monte Rosa Therapeutics, Inc.(GLUE) | 1,029,066 | 2,002,040 | +972,974 | $16.14M | $32.93M | 3.88% | +$16.80M |
| Erasca, Inc.(ERAS) | 1,317,584 | 1,851,812 | +534,228 | $4.90M | $29.96M | 3.53% | +$25.06M |
| Ascendis Pharma A/SADR(ASND) | 49,228 | 124,658 | +75,430 | $10.50M | $28.51M | 3.36% | +$18.02M |
| UroGen Pharma Ltd.(URGN) | 1,738,821 | 1,503,045 | -235,776 | $40.72M | $27.02M | 3.18% | -$13.70M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 135,950 | 306,000 | +170,050 | $14.55M | $26.61M | 3.14% | +$12.06M |
| Praxis Precision Medicines, Inc.(PRAX) | 82,465 | 71,552 | -10,913 | $24.31M | $23.05M | 2.72% | -$1.25M |
| Zenas BioPharma, Inc.(ZBIO) | 0 | 1,135,935 | +1,135,935 | $0 | $22.21M | 2.62% | +$22.21M |
| Syndax Pharmaceuticals, Inc.(SNDX) | 642,899 | 888,987 | +246,088 | $13.51M | $20.77M | 2.45% | +$7.26M |
| Centessa Pharmaceuticals PlcADS | 458,203 | 466,345 | +8,142 | $11.46M | $18.52M | 2.18% | +$7.06M |
| Scholar Rock Holding Corporation(SRRK) | 0 | 339,613 | +339,613 | $0 | $16.70M | 1.97% | +$16.70M |
| Alkermes plcSHS(ALKS) | 0 | 460,314 | +460,314 | $0 | $16.28M | 1.92% | +$16.28M |
| ORIC Pharmaceuticals, Inc.(ORIC) | 1,116,604 | 1,100,010 | -16,594 | $9.13M | $13.94M | 1.64% | +$4.80M |
| Disc Medicine, Inc.(IRON) | 0 | 196,028 | +196,028 | $0 | $12.53M | 1.48% | +$12.53M |
| Helix Acquisition Corp. IIICL A(HLXC) | 0 | 1,208,986 | +1,208,986 | $0 | $12.28M | 1.45% | +$12.28M |
| Xenon Pharmaceuticals Inc.(XENE) | 0 | 197,759 | +197,759 | $0 | $11.50M | 1.36% | +$11.50M |
| CG Oncology, Inc.(CGON) | 361,158 | 166,349 | -194,809 | $15.00M | $11.26M | 1.33% | -$3.74M |
| Immunovant, Inc.(IMVT) | 0 | 414,236 | +414,236 | $0 | $10.29M | 1.21% | +$10.29M |
| Spyre Therapeutics, Inc.(SYRE) | 187,737 | 186,618 | -1,119 | $6.15M | $9.41M | 1.11% | +$3.26M |
| Biogen Inc.(BIIB) | 75,412 | 50,967 | -24,445 | $13.27M | $9.34M | 1.10% | -$3.93M |
| Guardant Health, Inc.(GH) | 91,914 | 98,514 | +6,600 | $9.39M | $9.10M | 1.07% | -$288.4K |
| Vaxcyte, Inc.(PCVX) | 148,787 | 144,981 | -3,806 | $6.87M | $8.42M | 0.99% | +$1.56M |
| Savara Inc.(SVRA) | 0 | 1,430,982 | +1,430,982 | $0 | $7.81M | 0.92% | +$7.81M |
| Benitec Biopharma Inc.(BNTC) | 731,717 | 717,725 | -13,992 | $9.86M | $7.64M | 0.90% | -$2.21M |
| Oruka Therapeutics, Inc.(ORKA) | 0 | 150,908 | +150,908 | $0 | $7.40M | 0.87% | +$7.40M |
| Compugen Ltd.(CGEN) | 3,479,805 | 3,315,845 | -163,960 | $5.32M | $7.06M | 0.83% | +$1.74M |
| Trevi Therapeutics, Inc.(TRVI) | 541,240 | 511,127 | -30,113 | $6.78M | $6.10M | 0.72% | -$678.6K |
| Insmed Incorporated(INSM) | 71,256 | 35,850 | -35,406 | $12.40M | $5.86M | 0.69% | -$6.54M |
| Veracyte, Inc.(VCYT) | 357,558 | 179,700 | -177,858 | $15.05M | $5.79M | 0.68% | -$9.27M |
| Cerus Corporation(CERS) | 2,814,383 | 3,176,547 | +362,164 | $5.80M | $5.78M | 0.68% | -$16.3K |
| Celldex Therapeutics, Inc.(CLDX) | 191,074 | 178,378 | -12,696 | $5.19M | $5.66M | 0.67% | +$468.6K |
| C4 Therapeutics, Inc.(CCCC) | 1,994,224 | 1,911,785 | -82,439 | $3.81M | $5.03M | 0.59% | +$1.22M |
| Cytokinetics, Incorporated(CYTK) | 0 | 71,203 | +71,203 | $0 | $4.69M | 0.55% | +$4.69M |
| Climb Bio, Inc.(CLYM) | 0 | 684,908 | +684,908 | $0 | $4.69M | 0.55% | +$4.69M |
| Compass Therapeutics, Inc.(CMPX) | 1,051,343 | 859,049 | -192,294 | $5.65M | $4.54M | 0.54% | -$1.10M |
| Surrozen, Inc.(SRZN) | 157,323 | 144,255 | -13,068 | $3.56M | $4.20M | 0.50% | +$646.6K |
| Contineum Therapeutics, Inc.CL A(CTNM) | 307,540 | 301,729 | -5,811 | $3.52M | $3.94M | 0.46% | +$425.4K |
| Zura Bio LimitedCL A(ZURA) | 0 | 560,651 | +560,651 | $0 | $3.34M | 0.39% | +$3.34M |
| Fulcrum Therapeutics, Inc.(FULC) | 394,650 | 419,949 | +25,299 | $4.46M | $3.22M | 0.38% | -$1.24M |
| Abeona Therapeutics Inc.(ABEO) | 627,738 | 648,942 | +21,204 | $3.31M | $2.91M | 0.34% | -$400.9K |
| CAMP4 THERAPEUTICS CORPORATION(CAMP) | 0 | 653,594 | +653,594 | $0 | $2.88M | 0.34% | +$2.88M |
| Annexon, Inc.(ANNX) | 0 | 496,461 | +496,461 | $0 | $2.75M | 0.32% | +$2.75M |
| Elutia Inc.CL A(ELUT) | 2,751,314 | 2,498,020 | -253,294 | $1.91M | $2.62M | 0.31% | +$717.1K |
| Crescent Biopharma, Inc.(CBIO) | 0 | 130,500 | +130,500 | $0 | $2.40M | 0.28% | +$2.40M |
| Monopar Therapeutics Inc.(MNPR) | 0 | 43,488 | +43,488 | $0 | $2.38M | 0.28% | +$2.38M |
| Ovid Therapeutics Inc.(OVID) | 0 | 1,000,000 | +1,000,000 | $0 | $2.22M | 0.26% | +$2.22M |
| Nextcure Inc | 176,057 | 176,057 | 0 | $2.50M | $1.88M | 0.22% | -$618.0K |
| COMPASS Pathways plcADS(CMPS) | 0 | 300,000 | +300,000 | $0 | $1.66M | 0.20% | +$1.66M |
| Neumora Therapeutics, Inc.(NMRA) | 0 | 818,156 | +818,156 | $0 | $1.60M | 0.19% | +$1.60M |
| Sionna Therapeutics, Inc.(SION) | 41,460 | 39,417 | -2,043 | $1.71M | $1.58M | 0.19% | -$125.4K |
| TELA Bio, Inc.(TELA) | 2,647,512 | 2,259,312 | -388,200 | $3.12M | $1.40M | 0.17% | -$1.72M |
| Edgewise Therapeutics, Inc.(EWTX) | 42,052 | 42,615 | +563 | $1.04M | $1.34M | 0.16% | +$298.9K |
| Replimune Group, Inc.(REPL) | 0 | 171,936 | +171,936 | $0 | $1.32M | 0.15% | +$1.32M |
| Generate Biomedicines, Inc.(GENB) | 0 | 100,000 | +100,000 | $0 | $1.25M | 0.15% | +$1.25M |
| Radiopharm Theranostics LimitedADS(RADX) | 187,406 | 187,406 | 0 | $978.3K | $805.8K | 0.09% | -$172.4K |
| Fractyl Health, Inc.(GUTS) | 9,840,041 | 1,701,625 | -8,138,416 | $21.65M | $779.0K | 0.09% | -$20.87M |
| iBio, Inc.(IBIO) | 106,000 | 226,000 | +120,000 | $204.6K | $429.4K | 0.05% | +$224.8K |
| Adagio Medical Holdings, Inc.(ADGM) | 515,384 | 251,972 | -263,412 | $536.0K | $289.8K | 0.03% | -$246.2K |
| Aardvark Therapeutics Inc | 303,939 | 33,684 | -270,255 | $3.99M | $127.0K | 0.01% | -$3.86M |
| Rocket Pharmaceuticals, Inc.W EXP 09 02 202(RCKT) | 104,828 | 104,828 | 0 | $2.5K | $2.2K | 0.00% | -$388 |
| 4d Molecular Therapeutics In | 100,000 | 0 | -100,000 | $750.0K | $0 | — | -$750.0K |
| Amylyx Pharmaceuticals, Inc.(AMLX) | 506,242 | 0 | -506,242 | $6.12M | $0 | — | -$6.12M |
| Avalo Therapeutics, Inc.(AVTX) | 524,436 | 0 | -524,436 | $9.52M | $0 | — | -$9.52M |
| CytomX Therapeutics, Inc.(CTMX) | 385,974 | 0 | -385,974 | $1.64M | $0 | — | -$1.64M |
| Gossamer Bio, Inc.(GOSS) | 2,135,722 | 0 | -2,135,722 | $6.62M | $0 | — | -$6.62M |
| Kymera Therapeutics, Inc.(KYMR) | 34,589 | 0 | -34,589 | $2.69M | $0 | — | -$2.69M |
| Lexeo Therapeutics, Inc.(LXEO) | 617,608 | 0 | -617,608 | $6.13M | $0 | — | -$6.13M |
| Mineralys Therapeutics, Inc.(MLYS) | 94,983 | 0 | -94,983 | $3.45M | $0 | — | -$3.45M |
| Olema Pharmaceuticals, Inc.(OLMA) | 206,280 | 0 | -206,280 | $5.16M | $0 | — | -$5.16M |
| Palisade Bio, Inc.(PALI) | 102,108 | 0 | -102,108 | $240.0K | $0 | — | -$240.0K |
| Pfizer Inc.(PFE) | 419,134 | 0 | -419,134 | $10.44M | $0 | — | -$10.44M |
| Rapport Therapeutics, Inc.(RAPP) | 9,659 | 0 | -9,659 | $293.1K | $0 | — | -$293.1K |
| Relay Therapeutics, Inc.(RLAY) | 398,167 | 0 | -398,167 | $3.37M | $0 | — | -$3.37M |
| Soleno Therapeutics Inc | 117,485 | 0 | -117,485 | $5.44M | $0 | — | -$5.44M |
| Tarsus Pharmaceuticals, Inc.(TARS) | 36,124 | 0 | -36,124 | $2.96M | $0 | — | -$2.96M |
| uniQure N.V.SHS(QURE) | 126,047 | 0 | -126,047 | $3.02M | $0 | — | -$3.02M |
| Viridian Therapeutics, Inc.(VRDN) | 348,569 | 0 | -348,569 | $10.85M | $0 | — | -$10.85M |
| X4 Pharmaceuticals, Inc.(XFOR) | 357,387 | 0 | -357,387 | $1.43M | $0 | — | -$1.43M |