Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q1 2024 ▲▼ | Q2 2024 ▲▼ | Change ▲▼ | Q1 2024 ▲▼ | Q2 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| NUVALENT INC | 157,750 | 465,710 | +307,960 | 11,845 | 35,329 | 8.72% | +23,483 |
| ERASCA INC(ERAS) | 223,845 | 7,816,926 | +7,593,081 | 461 | 18,448 | 4.55% | +17,987 |
| MERUS N V | 566,287 | 623,628 | +57,341 | 25,500 | 36,900 | 9.11% | +11,400 |
| UROGEN PHARMA LTD(URGN) | 508,587 | 1,102,000 | +593,413 | 7,629 | 18,492 | 4.57% | +10,863 |
| INTRA-CELLULAR THERAPIES INC | 34,807 | 192,345 | +157,538 | 2,409 | 13,174 | 3.25% | +10,765 |
| ALNYLAM PHARMACEUTICALS INC(ALNY) | 0 | 36,000 | +36,000 | 0 | 8,748 | 2.16% | +8,748 |
| AVIDITY BIOSCIENCES INC | 489,303 | 517,734 | +28,431 | 12,487 | 21,149 | 5.22% | +8,662 |
| ELUTIA INC(ELUT) | 78,580 | 1,603,580 | +1,525,000 | 248 | 7,954 | 1.96% | +7,706 |
| SYNDAX PHARMACEUTICALS INC(SNDX) | 0 | 370,000 | +370,000 | 0 | 7,596 | 1.88% | +7,596 |
| SAREPTA THERAPEUTICS INC(SRPT) | 0 | 42,000 | +42,000 | 0 | 6,636 | 1.64% | +6,636 |
| CORBUS PHARMACEUTICALS HLDGS(CRBP) | 31,980 | 172,492 | +140,512 | 1,255 | 7,805 | 1.93% | +6,550 |
| INSMED INC(INSM) | 113,616 | 140,000 | +26,384 | 3,082 | 9,380 | 2.32% | +6,298 |
| ABIVAX SA(ABVX) | 75,000 | 455,800 | +380,800 | 1,073 | 6,026 | 1.49% | +4,953 |
| AKERO THERAPEUTICS INC | 399,949 | 625,087 | +225,138 | 10,103 | 14,665 | 3.62% | +4,562 |
| DISC MEDICINE INC(IRON) | 0 | 101,187 | +101,187 | 0 | 4,560 | 1.13% | +4,560 |
| BIOHAVEN LTD(BHVN) | 0 | 100,000 | +100,000 | 0 | 3,471 | 0.86% | +3,471 |
| GERON CORP(GERN) | 250,000 | 999,270 | +749,270 | 825 | 4,237 | 1.05% | +3,412 |
| ADC THERAPEUTICS SA(ADCT) | 501,222 | 1,768,770 | +1,267,548 | 2,250 | 5,589 | 1.38% | +3,339 |
| LONGBOARD PHARMACEUTICALS IN | 0 | 122,849 | +122,849 | 0 | 3,321 | 0.82% | +3,321 |
| COGENT BIOSCIENCES INC(COGT) | 1,036,667 | 1,206,214 | +169,547 | 6,966 | 10,168 | 2.51% | +3,202 |
| BIODESIX INC(BDSX) | 0 | 1,808,959 | +1,808,959 | 0 | 2,768 | 0.68% | +2,768 |
| PERSPECTIVE THERAPEUTICS INC(CATX) | 0 | 260,009 | +260,009 | 0 | 2,592 | 0.64% | +2,592 |
| ENGENE HOLDINGS INC COM | 0 | 263,841 | +263,841 | 0 | 2,488 | 0.61% | +2,488 |
| STRUCTURE THERAPEUTICS INC | 10,000 | 70,516 | +60,516 | 429 | 2,769 | 0.68% | +2,341 |
| VERONA PHARMA PLC | 136,714 | 304,633 | +167,919 | 2,200 | 4,405 | 1.09% | +2,205 |
| STOKE THERAPEUTICS INC(STOK) | 0 | 141,518 | +141,518 | 0 | 1,912 | 0.47% | +1,912 |
| CELLDEX THERAPEUTICS INC NEW(CLDX) | 299,316 | 374,910 | +75,594 | 12,562 | 13,875 | 3.43% | +1,313 |
| TARSUS PHARMACEUTICALS INC(TARS) | 0 | 40,000 | +40,000 | 0 | 1,087 | 0.27% | +1,087 |
| MIRUM PHARMACEUTICALS INC(MIRM) | 79,194 | 79,194 | 0 | 1,989 | 2,708 | 0.67% | +718 |
| VYNE THERAPEUTICS INC(YARW) | 86,383 | 467,397 | +381,014 | 265 | 921 | 0.23% | +656 |
| SOLENO THERAPEUTICS INC | 0 | 15,000 | +15,000 | 0 | 612 | 0.15% | +612 |
| BIOGEN INC(BIIB) | 19,365 | 19,365 | 0 | 4,176 | 4,489 | 1.11% | +314 |
| ZURA BIO LTD(ZURA) | 328,504 | 328,504 | 0 | 844 | 1,150 | 0.28% | +306 |
| TELA BIO INC(TELA) | 776,851 | 1,000,000 | +223,149 | 4,405 | 4,700 | 1.16% | +295 |
| VAXCYTE INC(PCVX) | 0 | 2,500 | +2,500 | 0 | 189 | 0.05% | +189 |
| OLEMA PHARMACEUTICALS INC(OLMA) | 515,317 | 546,863 | +31,546 | 5,833 | 5,917 | 1.46% | +84 |
| ROCKET PHARMACEUTICALS INC(RCKT) | 104,828 | 104,828 | 0 | 31 | 6 | 0.00% | -25 |
| KALVISTA PHARMACEUTICALS INC | 561,183 | 560,883 | -300 | 6,656 | 6,607 | 1.63% | -48 |
| COMPUGEN LTD(CGEN) | 1,000,000 | 1,501,113 | +501,113 | 2,580 | 2,522 | 0.62% | -58 |
| MOLECULAR TEMPLATES INC | 354,608 | 623,838 | +269,230 | 794 | 717 | 0.18% | -77 |
| HELIX ACQUISITION CORP II | 500,000 | 500,000 | 0 | 5,200 | 5,110 | 1.26% | -90 |
| VERACYTE INC(VCYT) | 280,773 | 282,248 | +1,475 | 6,222 | 6,116 | 1.51% | -106 |
| RELMADA THERAPEUTICS INC(RLMD) | 99,379 | 99,379 | 0 | 462 | 298 | 0.07% | -164 |
| IMMUNOME INC(IMNM) | 7,489 | 0 | -7,489 | 185 | 0 | — | -185 |
| CERUS CORP(CERS) | 1,465,744 | 1,465,744 | 0 | 2,770 | 2,580 | 0.64% | -191 |
| MODULAR MED INC | 900,000 | 900,000 | 0 | 1,665 | 1,422 | 0.35% | -243 |
| EVOGENE LTD | 3,085,503 | 3,079,739 | -5,764 | 2,314 | 2,003 | 0.49% | -311 |
| 89BIO INC | 92,298 | 92,298 | 0 | 1,074 | 739 | 0.18% | -335 |
| KARYOPHARM THERAPEUTICS INC(KPTI) | 558,466 | 558,466 | 0 | 843 | 485 | 0.12% | -359 |
| RHYTHM PHARMACEUTICALS INC(RYTM) | 183,776 | 184,662 | +886 | 7,963 | 7,582 | 1.87% | -381 |
| REZOLUTE INC(RZLT) | 151,985 | 0 | -151,985 | 388 | 0 | — | -388 |
| TREVI THERAPEUTICS INC(TRVI) | 844,235 | 844,235 | 0 | 2,913 | 2,516 | 0.62% | -397 |
| ALIGOS THERAPEUTICS INC | 655,515 | 655,515 | 0 | 642 | 229 | 0.06% | -413 |
| MORPHIC HLDG INC | 483,972 | 486,306 | +2,334 | 17,036 | 16,568 | 4.09% | -467 |
| FRACTYL HEALTH INC(GUTS) | 166,666 | 166,666 | 0 | 1,233 | 712 | 0.18% | -522 |
| WAVE LIFE SCIENCES LTD(WVE) | 495,471 | 495,471 | 0 | 3,057 | 2,472 | 0.61% | -585 |
| JASPER THERAPEUTICS INC(JSPR) | 109,892 | 109,892 | 0 | 3,226 | 2,495 | 0.62% | -732 |
| MINERALYS THERAPEUTICS INC(MLYS) | 56,944 | 0 | -56,944 | 735 | 0 | — | -735 |
| ADICET BIO INC | 331,279 | 0 | -331,279 | 779 | 0 | — | -779 |
| POSEIDA THERAPEUTICS INC | 3,596,476 | 3,607,999 | +11,523 | 11,473 | 10,535 | 2.60% | -937 |
| FULCRUM THERAPEUTICS INC(FULC) | 398,436 | 398,436 | 0 | 3,761 | 2,470 | 0.61% | -1,291 |
| AMYLYX PHARMACEUTICALS INC(AMLX) | 500,000 | 0 | -500,000 | 1,420 | 0 | — | -1,420 |
| VIKING THERAPEUTICS INC(VKTX) | 20,000 | 0 | -20,000 | 1,640 | 0 | — | -1,640 |
| TERNS PHARMACEUTICALS INC | 250,551 | 0 | -250,551 | 1,644 | 0 | — | -1,644 |
| KRYSTAL BIOTECH INC(KRYS) | 10,000 | 0 | -10,000 | 1,779 | 0 | — | -1,779 |
| GOSSAMER BIO INC(GOSS) | 6,130,268 | 5,500,000 | -630,268 | 7,234 | 4,955 | 1.22% | -2,279 |
| NEWAMSTERDAM PHARMA COMPANY ORDINARY SHARES | 99,612 | 0 | -99,612 | 2,356 | 0 | — | -2,356 |
| ROCKET PHARMACEUTICALS INC(RCKT) | 101,002 | 0 | -101,002 | 2,721 | 0 | — | -2,721 |
| PLIANT THERAPEUTICS INC(PLRX) | 183,392 | 0 | -183,392 | 2,733 | 0 | — | -2,733 |
| DEXCOM INC(DXCM) | 20,000 | 0 | -20,000 | 2,774 | 0 | — | -2,774 |
| XENON PHARMACEUTICALS INC(XENE) | 66,090 | 0 | -66,090 | 2,845 | 0 | — | -2,845 |
| APOGEE THERAPEUTICS INC(APGE) | 50,000 | 0 | -50,000 | 3,323 | 0 | — | -3,322 |
| CYTOKINETICS INC(CYTK) | 50,000 | 0 | -50,000 | 3,506 | 0 | — | -3,505 |
| SCHOLAR ROCK HLDG CORP(SRRK) | 199,415 | 0 | -199,415 | 3,542 | 0 | — | -3,542 |
| KODIAK SCIENCES INC(KOD) | 1,238,822 | 1,062,062 | -176,760 | 6,516 | 2,496 | 0.62% | -4,020 |
| EYEPOINT PHARMACEUTICALS INC(EYPT) | 247,968 | 100,000 | -147,968 | 5,125 | 870 | 0.21% | -4,255 |
| BOUNDLESS BIO INC(BOLD) | 312,500 | 0 | -312,500 | 4,453 | 0 | — | -4,453 |
| C4 THERAPEUTICS INC(CCCC) | 1,435,931 | 1,442,841 | +6,910 | 11,732 | 6,666 | 1.65% | -5,066 |
| MACROGENICS INC(MGNX) | 478,079 | 370,000 | -108,079 | 7,037 | 1,573 | 0.39% | -5,465 |
| CRINETICS PHARMACEUTICALS IN(CRNX) | 127,835 | 0 | -127,835 | 5,984 | 0 | — | -5,984 |
| ORIC PHARMACEUTICALS INC(ORIC) | 1,113,007 | 1,075,812 | -37,195 | 15,304 | 7,606 | 1.88% | -7,698 |
| ALPINE IMMUNE SCIENCES INC | 199,020 | 0 | -199,020 | 7,889 | 0 | — | -7,889 |
| MERSANA THERAPEUTICS INC | 2,968,798 | 2,500,585 | -468,213 | 13,300 | 5,026 | 1.24% | -8,274 |
| PRAXIS PRECISION MEDICINES I(PRAX) | 190,556 | 67,296 | -123,260 | 11,628 | 2,783 | 0.69% | -8,844 |
| PERSPECTIVE THERAPEUTICS INC(CATX) | 8,108,108 | 0 | -8,108,108 | 9,649 | 0 | — | -9,649 |
| SOLID BIOSCIENCES INC | 1,325,065 | 472,995 | -852,070 | 17,650 | 2,682 | 0.66% | -14,968 |