Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q2 2025 ▲▼ | Q3 2025 ▲▼ | Change ▲▼ | Q2 2025 ▲▼ | Q3 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| ABIVAX Société AnonymeADS(ABVX) | 0 | 539,704 | +539,704 | $0 | $45.82M | 6.63% | +$45.82M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 400,772 | 369,996 | -30,776 | $25.32M | $37.37M | 5.41% | +$12.04M |
| Avidity Biosciences Inc | 410,000 | 844,633 | +434,633 | $11.64M | $36.80M | 5.33% | +$25.16M |
| Nuvalent Inc | 235,583 | 372,300 | +136,717 | $17.97M | $32.20M | 4.66% | +$14.22M |
| UroGen Pharma Ltd.(URGN) | 2,022,482 | 1,577,283 | -445,199 | $27.71M | $31.47M | 4.56% | +$3.76M |
| Akero Therapeutics Inc | 713,811 | 643,636 | -70,175 | $38.09M | $30.56M | 4.42% | -$7.53M |
| Insmed Incorporated(INSM) | 249,060 | 206,648 | -42,412 | $25.07M | $29.76M | 4.31% | +$4.69M |
| Dianthus Therapeutics, Inc.(DNTH) | 95,806 | 674,966 | +579,160 | $1.78M | $26.56M | 3.85% | +$24.78M |
| uniQure N.V.SHS(QURE) | 202,565 | 455,000 | +252,435 | $2.82M | $26.56M | 3.84% | +$23.73M |
| CG Oncology, Inc.(CGON) | 541,034 | 638,346 | +97,312 | $14.07M | $25.71M | 3.72% | +$11.65M |
| ORIC Pharmaceuticals, Inc.(ORIC) | 1,800,829 | 1,948,808 | +147,979 | $18.28M | $23.39M | 3.39% | +$5.11M |
| Cidara Therapeutics Inc | 103,943 | 220,902 | +116,959 | $5.06M | $21.15M | 3.06% | +$16.09M |
| Fractyl Health, Inc.(GUTS) | 202,590 | 10,600,000 | +10,397,410 | $328.2K | $16.85M | 2.44% | +$16.53M |
| Kalvista Pharmaceuticals Inc | 1,832,171 | 1,363,378 | -468,793 | $20.71M | $16.61M | 2.40% | -$4.11M |
| Kodiak Sciences Inc.(KOD) | 401,540 | 1,000,000 | +598,460 | $1.50M | $16.37M | 2.37% | +$14.87M |
| Gossamer Bio, Inc.(GOSS) | 5,146,782 | 4,779,082 | -367,700 | $6.33M | $12.57M | 1.82% | +$6.24M |
| Cogent Biosciences, Inc.(COGT) | 0 | 815,075 | +815,075 | $0 | $11.70M | 1.69% | +$11.70M |
| Cytokinetics, Incorporated(CYTK) | 0 | 211,000 | +211,000 | $0 | $11.60M | 1.68% | +$11.60M |
| Vaxcyte, Inc.(PCVX) | 287,796 | 314,339 | +26,543 | $9.36M | $11.32M | 1.64% | +$1.97M |
| Biogen Inc.(BIIB) | 0 | 80,419 | +80,419 | $0 | $11.27M | 1.63% | +$11.27M |
| Ascendis Pharma A/SADR(ASND) | 86,552 | 53,554 | -32,998 | $14.94M | $10.65M | 1.54% | -$4.29M |
| Compass Therapeutics, Inc.(CMPX) | 1,249,781 | 2,833,988 | +1,584,207 | $3.25M | $9.92M | 1.44% | +$6.67M |
| Amylyx Pharmaceuticals, Inc.(AMLX) | 0 | 700,000 | +700,000 | $0 | $9.51M | 1.38% | +$9.51M |
| Verastem, Inc.(VSTM) | 0 | 1,042,757 | +1,042,757 | $0 | $9.21M | 1.33% | +$9.21M |
| Avalo Therapeutics, Inc.(AVTX) | 0 | 720,922 | +720,922 | $0 | $9.16M | 1.33% | +$9.16M |
| Olema Pharmaceuticals, Inc.(OLMA) | 0 | 933,541 | +933,541 | $0 | $9.14M | 1.32% | +$9.14M |
| Celldex Therapeutics, Inc.(CLDX) | 198,441 | 348,922 | +150,481 | $4.04M | $9.03M | 1.31% | +$4.99M |
| Scholar Rock Holding Corporation(SRRK) | 341,010 | 233,920 | -107,090 | $12.08M | $8.71M | 1.26% | -$3.37M |
| Veracyte, Inc.(VCYT) | 448,495 | 235,791 | -212,704 | $12.12M | $8.09M | 1.17% | -$4.03M |
| Syndax Pharmaceuticals, Inc.(SNDX) | 402,964 | 463,708 | +60,744 | $3.77M | $7.13M | 1.03% | +$3.36M |
| Rapport Therapeutics, Inc.(RAPP) | 0 | 203,946 | +203,946 | $0 | $6.06M | 0.88% | +$6.06M |
| Viridian Therapeutics, Inc.(VRDN) | 0 | 259,509 | +259,509 | $0 | $5.60M | 0.81% | +$5.60M |
| Alkermes plcSHS(ALKS) | 0 | 180,513 | +180,513 | $0 | $5.42M | 0.78% | +$5.42M |
| Trevi Therapeutics, Inc.(TRVI) | 539,587 | 588,789 | +49,202 | $2.95M | $5.39M | 0.78% | +$2.44M |
| BridgeBio Oncology Therapeutics, Inc.(BBOT) | 0 | 457,414 | +457,414 | $0 | $5.30M | 0.77% | +$5.30M |
| Abeona Therapeutics Inc.(ABEO) | 917,898 | 994,754 | +76,856 | $5.21M | $5.25M | 0.76% | +$38.6K |
| Lexeo Therapeutics, Inc.(LXEO) | 0 | 778,611 | +778,611 | $0 | $5.17M | 0.75% | +$5.17M |
| Monte Rosa Therapeutics, Inc.(GLUE) | 0 | 694,942 | +694,942 | $0 | $5.15M | 0.75% | +$5.15M |
| Compugen Ltd.(CGEN) | 3,033,879 | 3,311,165 | +277,286 | $5.40M | $4.87M | 0.70% | -$532.9K |
| Pharvaris N V COM | 0 | 183,903 | +183,903 | $0 | $4.59M | 0.66% | +$4.59M |
| Celcuity Inc.(CELC) | 0 | 88,686 | +88,686 | $0 | $4.38M | 0.63% | +$4.38M |
| Cerus Corporation(CERS) | 2,488,291 | 2,715,786 | +227,495 | $3.51M | $4.32M | 0.63% | +$809.6K |
| C4 Therapeutics, Inc.(CCCC) | 0 | 1,897,383 | +1,897,383 | $0 | $4.21M | 0.61% | +$4.21M |
| TELA Bio, Inc.(TELA) | 2,779,795 | 2,782,923 | +3,128 | $5.39M | $4.15M | 0.60% | -$1.25M |
| Aardvark Therapeutics Inc | 286,807 | 306,912 | +20,105 | $3.88M | $4.08M | 0.59% | +$201.2K |
| Bicara Therapeutics Inc | 0 | 250,606 | +250,606 | $0 | $3.96M | 0.57% | +$3.96M |
| Benitec Biopharma Inc.(BNTC) | 253,234 | 276,267 | +23,033 | $2.96M | $3.88M | 0.56% | +$913.2K |
| Kiniksa Pharmaceuticals International, plcCL A(KNSA) | 75,959 | 88,910 | +12,951 | $2.10M | $3.45M | 0.50% | +$1.35M |
| Centessa Pharmaceuticals PlcADS | 5,000 | 141,238 | +136,238 | $65.7K | $3.43M | 0.50% | +$3.36M |
| EyePoint, Inc.(EYPT) | 0 | 230,837 | +230,837 | $0 | $3.29M | 0.48% | +$3.29M |
| Sionna Therapeutics, Inc.(SION) | 186,015 | 108,801 | -77,214 | $3.23M | $3.20M | 0.46% | -$27.5K |
| Zura Bio LimitedCL A(ZURA) | 0 | 720,452 | +720,452 | $0 | $3.12M | 0.45% | +$3.12M |
| Mineralys Therapeutics, Inc.(MLYS) | 115,282 | 80,000 | -35,282 | $1.56M | $3.03M | 0.44% | +$1.47M |
| Erasca, Inc.(ERAS) | 2,569,591 | 1,368,075 | -1,201,516 | $3.26M | $2.98M | 0.43% | -$281.0K |
| Praxis Precision Medicines, Inc.(PRAX) | 10,000 | 51,210 | +41,210 | $420.5K | $2.71M | 0.39% | +$2.29M |
| Elutia Inc.CL A(ELUT) | 2,761,684 | 2,850,987 | +89,303 | $5.47M | $2.54M | 0.37% | -$2.93M |
| Delcath Systems, Inc.(DCTH) | 103,026 | 203,386 | +100,360 | $1.40M | $2.19M | 0.32% | +$785.2K |
| Crinetics Pharmaceuticals In | 0 | 50,000 | +50,000 | $0 | $2.08M | 0.30% | +$2.08M |
| CAMP4 THERAPEUTICS CORPORATION(CAMP) | 0 | 653,594 | +653,594 | $0 | $1.96M | 0.28% | +$1.96M |
| Contineum Therapeutics, Inc.CL A(CTNM) | 0 | 166,161 | +166,161 | $0 | $1.95M | 0.28% | +$1.95M |
| Dyne Therapeutics, Inc.(DYN) | 0 | 100,000 | +100,000 | $0 | $1.26M | 0.18% | +$1.26M |
| LB Pharmaceuticals Inc(LBRX) | 0 | 70,000 | +70,000 | $0 | $1.11M | 0.16% | +$1.11M |
| Mersana Therapeutics Inc | 0 | 133,636 | +133,636 | $0 | $1.04M | 0.15% | +$1.04M |
| Radiopharm Theranostics LimitedADS(RADX) | 187,406 | 187,406 | 0 | $869.6K | $1.03M | 0.15% | +$164.9K |
| Immunovant, Inc.(IMVT) | 0 | 50,000 | +50,000 | $0 | $806.0K | 0.12% | +$806.0K |
| Modular Med Inc | 710,363 | 639,531 | -70,832 | $529.2K | $447.5K | 0.06% | -$81.7K |
| Biodesix, Inc.(BDSX) | 0 | 49,607 | +49,607 | $0 | $374.5K | 0.05% | +$374.5K |
| MBX Biosciences, Inc.(MBX) | 0 | 15,000 | +15,000 | $0 | $262.5K | 0.04% | +$262.5K |
| Enliven Therapeutics Inc | 10,000 | 10,675 | +675 | $200.6K | $218.5K | 0.03% | +$17.9K |
| MoonLake ImmunotherapeuticsCL A(MLTX) | 82,023 | 30,000 | -52,023 | $3.87M | $215.1K | 0.03% | -$3.66M |
| Arcturus Therapeutics Holdings Inc.(ARCT) | 0 | 3,445 | +3,445 | $0 | $63.5K | 0.01% | +$63.5K |
| Nektar Therapeutics(NKTR) | 346 | 365 | +19 | $8.9K | $20.8K | 0.00% | +$11.8K |
| Rocket Pharmaceuticals, Inc.W EXP 09 02 202(RCKT) | 104,828 | 104,828 | 0 | $3.0K | $4.1K | 0.00% | +$1.1K |
| 89bio Inc | 2,037,087 | 0 | -2,037,087 | $20.00M | $0 | — | -$20.00M |
| Biodesix, Inc.(BDSX) | 1,070,367 | 0 | -1,070,367 | $302.1K | $0 | — | -$302.1K |
| Helix Acquisition Corp IiCL A | 613,393 | 0 | -613,393 | $6.51M | $0 | — | -$6.51M |
| Mersana Therapeutics Inc | 3,128,421 | 0 | -3,128,421 | $926.0K | $0 | — | -$926.0K |
| Merus N V | 741,972 | 0 | -741,972 | $39.03M | $0 | — | -$39.03M |
| Metsera Inc | 207,581 | 0 | -207,581 | $5.91M | $0 | — | -$5.91M |
| Neurocrine Biosciences, Inc.(NBIX) | 162,969 | 0 | -162,969 | $20.48M | $0 | — | -$20.48M |
| Oruka Therapeutics, Inc.(ORKA) | 165,389 | 0 | -165,389 | $1.85M | $0 | — | -$1.85M |
| Pfizer Inc.(PFE) | 344,338 | 0 | -344,338 | $8.35M | $0 | — | -$8.35M |
| Sagimet Biosciences Inc.COM SER A(SGMT) | 37,539 | 0 | -37,539 | $286.0K | $0 | — | -$286.0K |
| Soleno Therapeutics Inc | 204,591 | 0 | -204,591 | $17.14M | $0 | — | -$17.14M |
| Structure Therapeutics IncADS | 175,636 | 0 | -175,636 | $3.64M | $0 | — | -$3.64M |
| Tourmaline Bio Inc | 109,257 | 0 | -109,257 | $1.75M | $0 | — | -$1.75M |
| Verona Pharma PlcADS | 358,297 | 0 | -358,297 | $33.89M | $0 | — | -$33.89M |