Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| ABIVAX Société AnonymeADS(ABVX) | 539,704 | 422,193 | -117,511 | $45.82M | $56.93M | 8.24% | +$11.11M |
| Cogent Biosciences, Inc.(COGT) | 815,075 | 1,245,254 | +430,179 | $11.70M | $44.23M | 6.40% | +$32.53M |
| UroGen Pharma Ltd.(URGN) | 1,577,283 | 1,738,821 | +161,538 | $31.47M | $40.72M | 5.89% | +$9.26M |
| Kalvista Pharmaceuticals Inc | 1,363,378 | 2,427,118 | +1,063,740 | $16.61M | $39.20M | 5.67% | +$22.59M |
| Celcuity Inc.(CELC) | 88,686 | 375,132 | +286,446 | $4.38M | $37.42M | 5.41% | +$33.03M |
| Nuvalent Inc | 372,300 | 311,430 | -60,870 | $32.20M | $31.33M | 4.53% | -$869.8K |
| Dianthus Therapeutics, Inc.(DNTH) | 674,966 | 750,136 | +75,170 | $26.56M | $30.91M | 4.47% | +$4.35M |
| Kodiak Sciences Inc.(KOD) | 1,000,000 | 1,023,122 | +23,122 | $16.37M | $28.61M | 4.14% | +$12.24M |
| Praxis Precision Medicines, Inc.(PRAX) | 51,210 | 82,465 | +31,255 | $2.71M | $24.31M | 3.52% | +$21.59M |
| Immunome, Inc.(IMNM) | 0 | 1,126,210 | +1,126,210 | $0 | $24.19M | 3.50% | +$24.19M |
| Fractyl Health, Inc.(GUTS) | 10,600,000 | 9,840,041 | -759,959 | $16.85M | $21.65M | 3.13% | +$4.79M |
| Monte Rosa Therapeutics, Inc.(GLUE) | 694,942 | 1,029,066 | +334,124 | $5.15M | $16.14M | 2.33% | +$10.99M |
| Veracyte, Inc.(VCYT) | 235,791 | 357,558 | +121,767 | $8.09M | $15.05M | 2.18% | +$6.96M |
| CG Oncology, Inc.(CGON) | 638,346 | 361,158 | -277,188 | $25.71M | $15.00M | 2.17% | -$10.72M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 369,996 | 135,950 | -234,046 | $37.37M | $14.55M | 2.11% | -$22.81M |
| Syndax Pharmaceuticals, Inc.(SNDX) | 463,708 | 642,899 | +179,191 | $7.13M | $13.51M | 1.95% | +$6.37M |
| Biogen Inc.(BIIB) | 80,419 | 75,412 | -5,007 | $11.27M | $13.27M | 1.92% | +$2.01M |
| Insmed Incorporated(INSM) | 206,648 | 71,256 | -135,392 | $29.76M | $12.40M | 1.79% | -$17.36M |
| Centessa Pharmaceuticals PlcADS | 141,238 | 458,203 | +316,965 | $3.43M | $11.46M | 1.66% | +$8.03M |
| Viridian Therapeutics, Inc.(VRDN) | 259,509 | 348,569 | +89,060 | $5.60M | $10.85M | 1.57% | +$5.25M |
| Ascendis Pharma A/SADR(ASND) | 53,554 | 49,228 | -4,326 | $10.65M | $10.50M | 1.52% | -$149.7K |
| Pfizer Inc.(PFE) | 0 | 419,134 | +419,134 | $0 | $10.44M | 1.51% | +$10.44M |
| Benitec Biopharma Inc.(BNTC) | 276,267 | 731,717 | +455,450 | $3.88M | $9.86M | 1.43% | +$5.98M |
| Avalo Therapeutics, Inc.(AVTX) | 720,922 | 524,436 | -196,486 | $9.16M | $9.52M | 1.38% | +$360.8K |
| Guardant Health, Inc.(GH) | 0 | 91,914 | +91,914 | $0 | $9.39M | 1.36% | +$9.39M |
| ORIC Pharmaceuticals, Inc.(ORIC) | 1,948,808 | 1,116,604 | -832,204 | $23.39M | $9.13M | 1.32% | -$14.25M |
| Vaxcyte, Inc.(PCVX) | 314,339 | 148,787 | -165,552 | $11.32M | $6.87M | 0.99% | -$4.46M |
| Trevi Therapeutics, Inc.(TRVI) | 588,789 | 541,240 | -47,549 | $5.39M | $6.78M | 0.98% | +$1.39M |
| Gossamer Bio, Inc.(GOSS) | 4,779,082 | 2,135,722 | -2,643,360 | $12.57M | $6.62M | 0.96% | -$5.95M |
| Spyre Therapeutics, Inc.(SYRE) | 0 | 187,737 | +187,737 | $0 | $6.15M | 0.89% | +$6.15M |
| Lexeo Therapeutics, Inc.(LXEO) | 778,611 | 617,608 | -161,003 | $5.17M | $6.13M | 0.89% | +$962.9K |
| Amylyx Pharmaceuticals, Inc.(AMLX) | 700,000 | 506,242 | -193,758 | $9.51M | $6.12M | 0.88% | -$3.40M |
| Cerus Corporation(CERS) | 2,715,786 | 2,814,383 | +98,597 | $4.32M | $5.80M | 0.84% | +$1.48M |
| Compass Therapeutics, Inc.(CMPX) | 2,833,988 | 1,051,343 | -1,782,645 | $9.92M | $5.65M | 0.82% | -$4.27M |
| Soleno Therapeutics Inc | 0 | 117,485 | +117,485 | $0 | $5.44M | 0.79% | +$5.44M |
| Compugen Ltd.(CGEN) | 3,311,165 | 3,479,805 | +168,640 | $4.87M | $5.32M | 0.77% | +$456.7K |
| Celldex Therapeutics, Inc.(CLDX) | 348,922 | 191,074 | -157,848 | $9.03M | $5.19M | 0.75% | -$3.84M |
| Olema Pharmaceuticals, Inc.(OLMA) | 933,541 | 206,280 | -727,261 | $9.14M | $5.16M | 0.75% | -$3.98M |
| Erasca, Inc.(ERAS) | 1,368,075 | 1,317,584 | -50,491 | $2.98M | $4.90M | 0.71% | +$1.92M |
| Fulcrum Therapeutics, Inc.(FULC) | 0 | 394,650 | +394,650 | $0 | $4.46M | 0.65% | +$4.46M |
| Aardvark Therapeutics Inc | 306,912 | 303,939 | -2,973 | $4.08M | $3.99M | 0.58% | -$89.7K |
| C4 Therapeutics, Inc.(CCCC) | 1,897,383 | 1,994,224 | +96,841 | $4.21M | $3.81M | 0.55% | -$403.2K |
| Surrozen, Inc.(SRZN) | 0 | 157,323 | +157,323 | $0 | $3.56M | 0.51% | +$3.56M |
| Contineum Therapeutics, Inc.CL A(CTNM) | 166,161 | 307,540 | +141,379 | $1.95M | $3.52M | 0.51% | +$1.56M |
| Mineralys Therapeutics, Inc.(MLYS) | 80,000 | 94,983 | +14,983 | $3.03M | $3.45M | 0.50% | +$413.3K |
| Relay Therapeutics, Inc.(RLAY) | 0 | 398,167 | +398,167 | $0 | $3.37M | 0.49% | +$3.37M |
| Abeona Therapeutics Inc.(ABEO) | 994,754 | 627,738 | -367,016 | $5.25M | $3.31M | 0.48% | -$1.94M |
| TELA Bio, Inc.(TELA) | 2,782,923 | 2,647,512 | -135,411 | $4.15M | $3.12M | 0.45% | -$1.02M |
| uniQure N.V.SHS(QURE) | 455,000 | 126,047 | -328,953 | $26.56M | $3.02M | 0.44% | -$23.54M |
| Tarsus Pharmaceuticals, Inc.(TARS) | 0 | 36,124 | +36,124 | $0 | $2.96M | 0.43% | +$2.96M |
| Kymera Therapeutics, Inc.(KYMR) | 0 | 34,589 | +34,589 | $0 | $2.69M | 0.39% | +$2.69M |
| Nextcure Inc | 0 | 176,057 | +176,057 | $0 | $2.50M | 0.36% | +$2.50M |
| Elutia Inc.CL A(ELUT) | 2,850,987 | 2,751,314 | -99,673 | $2.54M | $1.91M | 0.28% | -$632.1K |
| Sionna Therapeutics, Inc.(SION) | 108,801 | 41,460 | -67,341 | $3.20M | $1.71M | 0.25% | -$1.49M |
| CytomX Therapeutics, Inc.(CTMX) | 0 | 385,974 | +385,974 | $0 | $1.64M | 0.24% | +$1.64M |
| X4 Pharmaceuticals, Inc.(XFOR) | 0 | 357,387 | +357,387 | $0 | $1.43M | 0.21% | +$1.43M |
| Edgewise Therapeutics, Inc.(EWTX) | 0 | 42,052 | +42,052 | $0 | $1.04M | 0.15% | +$1.04M |
| Radiopharm Theranostics LimitedADS(RADX) | 187,406 | 187,406 | 0 | $1.03M | $978.3K | 0.14% | -$56.2K |
| 4d Molecular Therapeutics In | 0 | 100,000 | +100,000 | $0 | $750.0K | 0.11% | +$750.0K |
| Adagio Medical Holdings, Inc.(ADGM) | 0 | 515,384 | +515,384 | $0 | $536.0K | 0.08% | +$536.0K |
| Rapport Therapeutics, Inc.(RAPP) | 203,946 | 9,659 | -194,287 | $6.06M | $293.1K | 0.04% | -$5.76M |
| Palisade Bio, Inc.(PALI) | 0 | 102,108 | +102,108 | $0 | $240.0K | 0.03% | +$240.0K |
| iBio, Inc.(IBIO) | 0 | 106,000 | +106,000 | $0 | $204.6K | 0.03% | +$204.6K |
| Rocket Pharmaceuticals, Inc.W EXP 09 02 202(RCKT) | 104,828 | 104,828 | 0 | $4.1K | $2.5K | 0.00% | -$1.6K |
| Akero Therapeutics Inc | 643,636 | 0 | -643,636 | $30.56M | $0 | — | -$30.56M |
| Alkermes plcSHS(ALKS) | 180,513 | 0 | -180,513 | $5.42M | $0 | — | -$5.42M |
| Arcturus Therapeutics Holdings Inc.(ARCT) | 3,445 | 0 | -3,445 | $63.5K | $0 | — | -$63.5K |
| Avidity Biosciences Inc | 844,633 | 0 | -844,633 | $36.80M | $0 | — | -$36.80M |
| Bicara Therapeutics Inc | 250,606 | 0 | -250,606 | $3.96M | $0 | — | -$3.96M |
| Biodesix, Inc.(BDSX) | 49,607 | 0 | -49,607 | $374.5K | $0 | — | -$374.5K |
| BridgeBio Oncology Therapeutics, Inc.(BBOT) | 457,414 | 0 | -457,414 | $5.30M | $0 | — | -$5.30M |
| CAMP4 THERAPEUTICS CORPORATION(CAMP) | 653,594 | 0 | -653,594 | $1.96M | $0 | — | -$1.96M |
| Cidara Therapeutics Inc | 220,902 | 0 | -220,902 | $21.15M | $0 | — | -$21.15M |
| Crinetics Pharmaceuticals In | 50,000 | 0 | -50,000 | $2.08M | $0 | — | -$2.08M |
| Cytokinetics, Incorporated(CYTK) | 211,000 | 0 | -211,000 | $11.60M | $0 | — | -$11.60M |
| Delcath Systems, Inc.(DCTH) | 203,386 | 0 | -203,386 | $2.19M | $0 | — | -$2.19M |
| Dyne Therapeutics, Inc.(DYN) | 100,000 | 0 | -100,000 | $1.26M | $0 | — | -$1.26M |
| Enliven Therapeutics Inc | 10,675 | 0 | -10,675 | $218.5K | $0 | — | -$218.5K |
| EyePoint, Inc.(EYPT) | 230,837 | 0 | -230,837 | $3.29M | $0 | — | -$3.29M |
| Immunovant, Inc.(IMVT) | 50,000 | 0 | -50,000 | $806.0K | $0 | — | -$806.0K |
| Kiniksa Pharmaceuticals International, plcCL A(KNSA) | 88,910 | 0 | -88,910 | $3.45M | $0 | — | -$3.45M |
| LB Pharmaceuticals Inc(LBRX) | 70,000 | 0 | -70,000 | $1.11M | $0 | — | -$1.11M |
| MBX Biosciences, Inc.(MBX) | 15,000 | 0 | -15,000 | $262.5K | $0 | — | -$262.5K |
| Mersana Therapeutics Inc | 133,636 | 0 | -133,636 | $1.04M | $0 | — | -$1.04M |
| Modular Med Inc | 639,531 | 0 | -639,531 | $447.5K | $0 | — | -$447.5K |
| MoonLake ImmunotherapeuticsCL A(MLTX) | 30,000 | 0 | -30,000 | $215.1K | $0 | — | -$215.1K |
| Nektar Therapeutics(NKTR) | 365 | 0 | -365 | $20.8K | $0 | — | -$20.8K |
| Pharvaris N V COM | 183,903 | 0 | -183,903 | $4.59M | $0 | — | -$4.59M |
| Scholar Rock Holding Corporation(SRRK) | 233,920 | 0 | -233,920 | $8.71M | $0 | — | -$8.71M |
| Verastem, Inc.(VSTM) | 1,042,757 | 0 | -1,042,757 | $9.21M | $0 | — | -$9.21M |
| Zura Bio LimitedCL A(ZURA) | 720,452 | 0 | -720,452 | $3.12M | $0 | — | -$3.12M |