Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Relay Therapeutics, Inc.(RLAY) | 17,000,000 | 17,000,000 | 0 | $143.82M | $169.15M | 9.79% | +$25.33M |
| Alkermes plcSHS(ALKS) | 3,550,000 | 4,200,000 | +650,000 | $99.33M | $148.51M | 8.59% | +$49.18M |
| Enliven Therapeutics Inc | 4,692,809 | 3,275,000 | -1,417,809 | $72.27M | $128.38M | 7.43% | +$56.11M |
| Cogent Biosciences, Inc.(COGT) | 2,196,845 | 2,888,007 | +691,162 | $78.03M | $111.16M | 6.43% | +$33.13M |
| Spyre Therapeutics, Inc.(SYRE) | 2,388,245 | 1,912,380 | -475,865 | $78.24M | $96.46M | 5.58% | +$18.22M |
| Tyra Biosciences, Inc.(TYRA) | 3,375,000 | 2,475,000 | -900,000 | $88.73M | $94.79M | 5.48% | +$6.06M |
| Celldex Therapeutics, Inc.(CLDX) | 2,565,000 | 2,696,616 | +131,616 | $69.67M | $85.54M | 4.95% | +$15.87M |
| Nuvalent Inc | 550,000 | 833,600 | +283,600 | $55.32M | $85.40M | 4.94% | +$30.08M |
| Amylyx Pharmaceuticals, Inc.(AMLX) | 5,650,000 | 5,650,000 | 0 | $68.25M | $78.53M | 4.54% | +$10.28M |
| Kymera Therapeutics, Inc.(KYMR) | 750,000 | 750,000 | 0 | $58.36M | $62.47M | 3.61% | +$4.11M |
| Alto Neuroscience, Inc.(ANRO) | 1,823,196 | 2,723,196 | +900,000 | $32.45M | $61.22M | 3.54% | +$28.76M |
| Pharvaris N V COM | 1,889,445 | 1,918,970 | +29,525 | $52.43M | $54.21M | 3.14% | +$1.78M |
| Erasca, Inc.(ERAS) | 0 | 3,175,000 | +3,175,000 | $0 | $51.37M | 2.97% | +$51.37M |
| Damora Therapeutics, Inc.(DMRA) | 0 | 1,939,000 | +1,939,000 | $0 | $50.22M | 2.91% | +$50.22M |
| Xenon Pharmaceuticals Inc.(XENE) | 1,800,000 | 825,000 | -975,000 | $80.68M | $47.97M | 2.78% | -$32.70M |
| Definium Therapeutics, Inc.(DFTX) | 0 | 2,000,000 | +2,000,000 | $0 | $37.80M | 2.19% | +$37.80M |
| LB Pharmaceuticals Inc(LBRX) | 1,500,000 | 1,500,000 | 0 | $33.39M | $36.99M | 2.14% | +$3.60M |
| EyePoint, Inc.(EYPT) | 0 | 2,825,000 | +2,825,000 | $0 | $36.41M | 2.11% | +$36.41M |
| Nurix Therapeutics, Inc.(NRIX) | 2,275,000 | 2,275,000 | 0 | $43.16M | $35.26M | 2.04% | -$7.89M |
| Corvus Pharmaceuticals, Inc.(CRVS) | 0 | 2,258,735 | +2,258,735 | $0 | $33.05M | 1.91% | +$33.05M |
| Assembly Biosciences Inc | 1,000,000 | 1,000,000 | 0 | $34.01M | $27.75M | 1.61% | -$6.26M |
| Perspective Therapeutics, Inc.(CATX) | 0 | 6,336,782 | +6,336,782 | $0 | $26.42M | 1.53% | +$26.42M |
| Soleno Therapeutics Inc | 1,200,000 | 652,432 | -547,568 | $55.56M | $21.84M | 1.26% | -$33.72M |
| Ocular Therapeutix, Inc.(OCUL) | 0 | 2,575,000 | +2,575,000 | $0 | $21.81M | 1.26% | +$21.81M |
| Century Therapeutics, Inc.(IPSC) | 0 | 8,695,652 | +8,695,652 | $0 | $19.65M | 1.14% | +$19.65M |
| Zura Bio LimitedCL A(ZURA) | 0 | 3,250,000 | +3,250,000 | $0 | $19.34M | 1.12% | +$19.34M |
| SAB Biotherapeutics, Inc.(SABS) | 4,401,500 | 4,401,500 | 0 | $16.46M | $16.86M | 0.98% | +$396.1K |
| Palisade Bio, Inc.(PALI) | 11,445,000 | 7,181,062 | -4,263,938 | $26.90M | $12.57M | 0.73% | -$14.33M |
| Karyopharm Therapeutics Inc.(KPTI) | 0 | 1,950,000 | +1,950,000 | $0 | $10.86M | 0.63% | +$10.86M |
| Inhibikase Therapeutics, Inc.(IKT) | 5,397,488 | 5,397,488 | 0 | $11.06M | $9.07M | 0.52% | -$2.00M |
| An2 Therapeutics Inc | 0 | 2,333,713 | +2,333,713 | $0 | $7.98M | 0.46% | +$7.98M |
| PepGen Inc.(PEPG) | 3,400,000 | 4,475,000 | +1,075,000 | $22.13M | $7.92M | 0.46% | -$14.21M |
| Avalo Therapeutics, Inc.(AVTX) | 483,000 | 483,000 | 0 | $8.77M | $7.21M | 0.42% | -$1.56M |
| Helix Acquisition Corp. IIICL A(HLXC) | 0 | 500,000 | +500,000 | $0 | $5.08M | 0.29% | +$5.08M |
| LeonaBio, Inc.(LONA) | 464,398 | 464,398 | 0 | $3.52M | $4.77M | 0.28% | +$1.26M |
| Relmada Therapeutics, Inc.(RLMD) | 0 | 633,901 | +633,901 | $0 | $4.41M | 0.26% | +$4.41M |
| Bright Minds Biosciences Inc.(DRUG) | 18,851 | 0 | -18,851 | $1.47M | $0 | — | -$1.47M |
| Centessa Pharmaceuticals PlcADS | 1,000,000 | 0 | -1,000,000 | $25.01M | $0 | — | -$25.01M |
| Contineum Therapeutics, Inc.CL A(CTNM) | 816,326 | 0 | -816,326 | $9.33M | $0 | — | -$9.33M |
| CytomX Therapeutics, Inc.(CTMX) | 7,692,300 | 0 | -7,692,300 | $32.77M | $0 | — | -$32.77M |
| Oruka Therapeutics, Inc.(ORKA) | 1,753,054 | 0 | -1,753,054 | $53.14M | $0 | — | -$53.14M |
| Protagonist Therapeutics Inc | 450,000 | 0 | -450,000 | $39.30M | $0 | — | -$39.30M |
| Rapt Therapeutics Inc | 250,000 | 0 | -250,000 | $8.47M | $0 | — | -$8.47M |
| Replimune Group, Inc.(REPL) | 1,425,000 | 0 | -1,425,000 | $13.85M | $0 | — | -$13.85M |
| Terns Pharmaceuticals Inc | 1,475,000 | 0 | -1,475,000 | $59.59M | $0 | — | -$59.59M |
| Mind Medicine Mindmed Inc | 2,000,000 | 0 | -2,000,000 | $26.78M | $0 | — | -$26.78M |