Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Relay Therapeutics, Inc.(RLAY) | 17,000,000 | 17,000,000 | 0 | $88.74M | $143.82M | 9.57% | +$55.08M |
| Alkermes plcSHS(ALKS) | 3,096,754 | 3,550,000 | +453,246 | $92.90M | $99.33M | 6.61% | +$6.43M |
| Tyra Biosciences, Inc.(TYRA) | 3,375,000 | 3,375,000 | 0 | $47.22M | $88.73M | 5.91% | +$41.51M |
| Xenon Pharmaceuticals Inc.(XENE) | 2,700,000 | 1,800,000 | -900,000 | $108.41M | $80.68M | 5.37% | -$27.73M |
| Spyre Therapeutics, Inc.(SYRE) | 1,988,084 | 2,388,245 | +400,161 | $33.32M | $78.24M | 5.21% | +$44.92M |
| Cogent Biosciences, Inc.(COGT) | 7,250,000 | 2,196,845 | -5,053,155 | $104.11M | $78.03M | 5.19% | -$26.08M |
| Enliven Therapeutics Inc | 4,692,809 | 4,692,809 | 0 | $96.06M | $72.27M | 4.81% | -$23.79M |
| Celldex Therapeutics, Inc.(CLDX) | 3,028,335 | 2,565,000 | -463,335 | $78.34M | $69.67M | 4.64% | -$8.68M |
| Amylyx Pharmaceuticals, Inc.(AMLX) | 4,075,478 | 5,650,000 | +1,574,522 | $55.39M | $68.25M | 4.54% | +$12.87M |
| Terns Pharmaceuticals Inc | 5,700,000 | 1,475,000 | -4,225,000 | $42.81M | $59.59M | 3.97% | +$16.78M |
| Kymera Therapeutics, Inc.(KYMR) | 750,000 | 750,000 | 0 | $42.45M | $58.36M | 3.88% | +$15.91M |
| Soleno Therapeutics Inc | 1,350,000 | 1,200,000 | -150,000 | $91.26M | $55.56M | 3.70% | -$35.70M |
| Nuvalent Inc | 1,400,000 | 550,000 | -850,000 | $121.07M | $55.32M | 3.68% | -$65.75M |
| Oruka Therapeutics, Inc.(ORKA) | 1,753,054 | 1,753,054 | 0 | $33.71M | $53.14M | 3.54% | +$19.42M |
| Pharvaris N V COM | 2,418,476 | 1,889,445 | -529,031 | $60.34M | $52.43M | 3.49% | -$7.91M |
| Nurix Therapeutics, Inc.(NRIX) | 3,780,055 | 2,275,000 | -1,505,055 | $34.93M | $43.16M | 2.87% | +$8.23M |
| Protagonist Therapeutics Inc | 1,025,000 | 450,000 | -575,000 | $68.09M | $39.30M | 2.62% | -$28.79M |
| Assembly Biosciences Inc | 1,000,000 | 1,000,000 | 0 | $25.60M | $34.01M | 2.26% | +$8.41M |
| LB Pharmaceuticals Inc(LBRX) | 1,500,000 | 1,500,000 | 0 | $23.68M | $33.39M | 2.22% | +$9.71M |
| CytomX Therapeutics, Inc.(CTMX) | 7,692,300 | 7,692,300 | 0 | $24.54M | $32.77M | 2.18% | +$8.23M |
| Alto Neuroscience, Inc.(ANRO) | 0 | 1,823,196 | +1,823,196 | $0 | $32.45M | 2.16% | +$32.45M |
| Palisade Bio, Inc.(PALI) | 0 | 11,445,000 | +11,445,000 | $0 | $26.90M | 1.79% | +$26.90M |
| Mind Medicine Mindmed Inc | 3,225,000 | 2,000,000 | -1,225,000 | $38.02M | $26.78M | 1.78% | -$11.24M |
| Centessa Pharmaceuticals PlcADS | 2,850,000 | 1,000,000 | -1,850,000 | $69.11M | $25.01M | 1.66% | -$44.10M |
| PepGen Inc.(PEPG) | 2,357,319 | 3,400,000 | +1,042,681 | $10.89M | $22.13M | 1.47% | +$11.24M |
| SAB Biotherapeutics, Inc.(SABS) | 4,401,500 | 4,401,500 | 0 | $8.85M | $16.46M | 1.10% | +$7.61M |
| Replimune Group, Inc.(REPL) | 0 | 1,425,000 | +1,425,000 | $0 | $13.85M | 0.92% | +$13.85M |
| Inhibikase Therapeutics, Inc.(IKT) | 5,397,488 | 5,397,488 | 0 | $8.74M | $11.06M | 0.74% | +$2.32M |
| Contineum Therapeutics, Inc.CL A(CTNM) | 0 | 816,326 | +816,326 | $0 | $9.33M | 0.62% | +$9.33M |
| Avalo Therapeutics, Inc.(AVTX) | 483,000 | 483,000 | 0 | $6.14M | $8.77M | 0.58% | +$2.63M |
| Rapt Therapeutics Inc | 0 | 250,000 | +250,000 | $0 | $8.47M | 0.56% | +$8.47M |
| LeonaBio, Inc.(LONA) | 0 | 464,398 | +464,398 | $0 | $3.52M | 0.23% | +$3.52M |
| Bright Minds Biosciences Inc.(DRUG) | 500,000 | 18,851 | -481,149 | $30.33M | $1.47M | 0.10% | -$28.86M |
| Agios Pharmaceuticals, Inc.(AGIO) | 2,338,287 | 0 | -2,338,287 | $93.86M | $0 | — | -$93.86M |
| Apogee Therapeutics Inc | 290,000 | 0 | -290,000 | $11.52M | $0 | — | -$11.52M |
| Crescent Biopharma, Inc.(CBIO) | 450,829 | 0 | -450,829 | $5.36M | $0 | — | -$5.36M |
| Cidara Therapeutics Inc | 585,000 | 0 | -585,000 | $56.02M | $0 | — | -$56.02M |
| Enanta Pharmaceuticals, Inc.(ENTA) | 800,000 | 0 | -800,000 | $9.58M | $0 | — | -$9.58M |
| Merus N V | 3,525,000 | 0 | -3,525,000 | $331.88M | $0 | — | -$331.88M |
| Perceptive Cap Solutions CorCL A CL A ORD SHS | 750,000 | 0 | -750,000 | $7.92M | $0 | — | -$7.92M |
| Tango Therapeutics, Inc.(TNGX) | 1,500,000 | 0 | -1,500,000 | $12.60M | $0 | — | -$12.60M |
| Viridian Therapeutics, Inc.(VRDN) | 3,200,000 | 0 | -3,200,000 | $69.06M | $0 | — | -$69.06M |
| Vistagen Therapeutics, Inc.(VTGN) | 1,575,000 | 0 | -1,575,000 | $5.59M | $0 | — | -$5.59M |