Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2024 ▲▼ | Q1 2025 ▲▼ | Change ▲▼ | Q4 2024 ▲▼ | Q1 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| NUVATION BIO INC(NUVB) | 312,336 | 27,330,800 | +27,018,464 | 831 | 48,102 | 6.57% | +47,271 |
| NUVATION BIO INC(SNDX) | 904,000 | 27,330,800 | +26,426,800 | 11,951 | 48,102 | 6.57% | +36,151 |
| TREVI THERAPEUTICS INC(TRVI) | 0 | 3,322,000 | +3,322,000 | 0 | 20,895 | 2.85% | +20,895 |
| TAYSHA GENE THERAPIES INC(APGE) | 0 | 10,700,000 | +10,700,000 | 0 | 14,873 | 2.03% | +14,873 |
| VERONA PHARMA PLC(HUMA) | 0 | 217,264 | +217,264 | 0 | 13,794 | 1.88% | +13,794 |
| TOURMALINE BIO INC | 0 | 905,000 | +905,000 | 0 | 13,765 | 1.88% | +13,765 |
| MOONLAKE IMMUNOTHERAPEUTICS(MLTX) | 0 | 296,000 | +296,000 | 0 | 11,565 | 1.58% | +11,565 |
| VERASTEM INC(IBRX) | 0 | 1,720,000 | +1,720,000 | 0 | 10,372 | 1.42% | +10,372 |
| VERASTEM INC(VSTM) | 0 | 1,720,000 | +1,720,000 | 0 | 10,372 | 1.42% | +10,372 |
| ARS PHARMACEUTICALS INC(VSTM) | 0 | 625,000 | +625,000 | 0 | 7,863 | 1.07% | +7,863 |
| ARS PHARMACEUTICALS INC(SPRY) | 0 | 625,000 | +625,000 | 0 | 7,863 | 1.07% | +7,863 |
| ABIVAX SA(ABVX) | 0 | 1,230,000 | +1,230,000 | 0 | 7,688 | 1.05% | +7,688 |
| ATYR PHARMA INC | 900,000 | 3,552,000 | +2,652,000 | 3,258 | 10,727 | 1.47% | +7,469 |
| VIRIDIAN THERAPEUTICS INC(CAPR) | 0 | 450,000 | +450,000 | 0 | 6,066 | 0.83% | +6,066 |
| MAZE THERAPEUTICS INC(MAZE) | 0 | 468,000 | +468,000 | 0 | 5,153 | 0.70% | +5,153 |
| MAZE THERAPEUTICS INC(NUVB) | 312,336 | 468,000 | +155,664 | 831 | 5,153 | 0.70% | +4,322 |
| KALVISTA PHARMACEUTICALS INC | 1,370,000 | 1,370,000 | 0 | 11,604 | 15,810 | 2.16% | +4,206 |
| CENTESSA PHARMACEUTICALS PLC(GOSS) | 18,350,000 | 1,425,000 | -16,925,000 | 16,599 | 20,492 | 2.80% | +3,892 |
| KALARIS THERAPEUTICS INC(KLRS) | 0 | 481,000 | +481,000 | 0 | 3,862 | 0.53% | +3,862 |
| GOSSAMER BIO INC(GOSS) | 18,350,000 | 18,350,000 | 0 | 16,599 | 20,185 | 2.76% | +3,586 |
| HELIX ACQUISITION CORP II(MLTX) | 0 | 250,000 | +250,000 | 0 | 2,825 | 0.39% | +2,825 |
| UNICYCIVE THERAPEUTICS INC | 900,000 | 10,000,000 | +9,100,000 | 3,258 | 5,749 | 0.79% | +2,491 |
| REGULUS THERAPEUTICS INC | 4,848,802 | 4,637,076 | -211,726 | 7,661 | 8,115 | 1.11% | +454 |
| HELIX ACQUISITION CORP II | 250,000 | 250,000 | 0 | 2,625 | 2,825 | 0.39% | +200 |
| MERUS N V | 308,000 | 308,000 | 0 | 12,951 | 12,964 | 1.77% | +12 |
| OCULAR THERAPEUTIX INC(TSHA) | 10,450,000 | 2,425,000 | -8,025,000 | 18,079 | 17,775 | 2.43% | -303 |
| GOSSAMER BIO INC | 3,018,000 | 18,350,000 | +15,332,000 | 21,005 | 20,185 | 2.76% | -820 |
| SYNDAX PHARMACEUTICALS INC(SNDX) | 904,000 | 904,000 | 0 | 11,951 | 11,106 | 1.52% | -845 |
| MERSANA THERAPEUTICS INC | 992,000 | 0 | -992,000 | 1,419 | 0 | — | -1,419 |
| UNICYCIVE THERAPEUTICS INC | 10,000,000 | 10,000,000 | 0 | 7,942 | 5,749 | 0.79% | -2,193 |
| PERSPECTIVE THERAPEUTICS INC(CATX) | 2,304,752 | 2,250,000 | -54,752 | 7,352 | 4,793 | 0.65% | -2,560 |
| PHARVARIS N V COM | 778,000 | 769,815 | -8,185 | 14,914 | 12,086 | 1.65% | -2,828 |
| OCULAR THERAPEUTIX INC(OCUL) | 2,425,000 | 2,425,000 | 0 | 20,710 | 17,775 | 2.43% | -2,934 |
| TAYSHA GENE THERAPIES INC(TSHA) | 10,450,000 | 10,700,000 | +250,000 | 18,079 | 14,873 | 2.03% | -3,205 |
| MIND MEDICINE MINDMED INC | 3,018,000 | 3,018,000 | 0 | 21,005 | 17,655 | 2.41% | -3,350 |
| NEUROGENE INC(NGNE) | 303,000 | 303,000 | 0 | 6,927 | 3,548 | 0.48% | -3,378 |
| DIANTHUS THERAPEUTICS INC(DNTH) | 2,110,167 | 2,341,667 | +231,500 | 46,002 | 42,478 | 5.80% | -3,524 |
| ALLOVIR INC | 11,215,000 | 0 | -11,215,000 | 4,710 | 0 | — | -4,710 |
| COGENT BIOSCIENCES INC(COGT) | 2,763,000 | 2,763,000 | 0 | 21,551 | 16,550 | 2.26% | -5,001 |
| CORBUS PHARMACEUTICALS HLDGS | 1,370,000 | 1,115,000 | -255,000 | 11,604 | 5,921 | 0.81% | -5,683 |
| ERASCA INC(ERAS) | 5,136,795 | 5,136,795 | 0 | 12,893 | 7,037 | 0.96% | -5,856 |
| NUVATION BIO INC(SRRK) | 488,000 | 7,900,000 | +7,412,000 | 21,091 | 13,904 | 1.90% | -7,187 |
| CORBUS PHARMACEUTICALS HLDGS(CRBP) | 1,115,000 | 1,115,000 | 0 | 13,157 | 5,921 | 0.81% | -7,236 |
| PERSPECTIVE THERAPEUTICS INC(ERAS) | 5,136,795 | 2,250,000 | -2,886,795 | 12,893 | 4,793 | 0.65% | -8,101 |
| MOONLAKE IMMUNOTHERAPEUTICS(OCUL) | 2,425,000 | 296,000 | -2,129,000 | 20,710 | 11,565 | 1.58% | -9,145 |
| SCHOLAR ROCK HLDG CORP(SRRK) | 488,000 | 329,000 | -159,000 | 21,091 | 10,577 | 1.44% | -10,514 |
| NUVATION BIO INC(NUVB) | 9,202,907 | 7,900,000 | -1,302,907 | 24,480 | 13,904 | 1.90% | -10,576 |
| VIRIDIAN THERAPEUTICS INC(VRDN) | 870,000 | 450,000 | -420,000 | 16,678 | 6,066 | 0.83% | -10,612 |
| BRIDGEBIO PHARMA INC(BBIO) | 441,600 | 0 | -441,600 | 12,118 | 0 | — | -12,118 |
| VERONA PHARMA PLC | 571,264 | 217,264 | -354,000 | 26,530 | 13,794 | 1.88% | -12,735 |
| CENTESSA PHARMACEUTICALS PLC | 1,993,052 | 1,425,000 | -568,052 | 33,384 | 20,492 | 2.80% | -12,892 |
| DYNE THERAPEUTICS INC(DYN) | 668,000 | 0 | -668,000 | 15,738 | 0 | — | -15,738 |
| SCHOLAR ROCK HOLDING CORP | 571,264 | 329,000 | -242,264 | 26,530 | 10,577 | 1.44% | -15,952 |
| ARRIVENT BIOPHARMA INC(AVBP) | 2,059,387 | 2,059,387 | 0 | 54,862 | 38,078 | 5.20% | -16,784 |
| KALARIS THERAPEUTICS INC(NUVB) | 9,202,907 | 481,000 | -8,721,907 | 24,480 | 3,862 | 0.53% | -20,617 |
| INSMED INC(INSM) | 332,000 | 0 | -332,000 | 22,921 | 0 | — | -22,921 |
| APELLIS PHARMACEUTICALS INC COM | 3,006,980 | 2,094,000 | -912,980 | 95,953 | 45,796 | 6.26% | -50,157 |