Octagon Capital Advisors LP
Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| DIANTHUS THERAPEUTICS INC(DNTH) | 2,416,667 | 1,946,667 | -470,000 | 99,590,847 | 163,364,295 | 18.08% | +63,773,448 |
| DEFINIUM THERAPEUTICS INC(DFTX) | 0 | 2,440,000 | +2,440,000 | 0 | 46,116,000 | 5.10% | +46,116,000 |
| ALUMIS INC | 2,530,700 | 2,830,700 | +300,000 | 24,699,632 | 62,360,321 | 6.90% | +37,660,689 |
| MIRUM PHARMACEUTICALS INC(MIRM) | 0 | 338,900 | +338,900 | 0 | 31,307,582 | 3.46% | +31,307,582 |
| XENON PHARMACEUTICALS INC(XENE) | 0 | 490,000 | +490,000 | 0 | 28,493,500 | 3.15% | +28,493,500 |
| TERNS PHARMACEUTICALS INC | 0 | 530,000 | +530,000 | 0 | 27,941,600 | 3.09% | +27,941,600 |
| DISC MEDICINE INC(IRON) | 0 | 270,000 | +270,000 | 0 | 17,263,800 | 1.91% | +17,263,800 |
| AKTIS ONCOLOGY INC(AKTS) | 0 | 960,847 | +960,847 | 0 | 17,189,553 | 1.90% | +17,189,553 |
| CONTEXT THERAPEUTICS INC | 0 | 5,250,000 | +5,250,000 | 0 | 13,755,000 | 1.52% | +13,755,000 |
| CENTESSA PHARMACEUTICALS PLC | 750,000 | 750,000 | 0 | 18,757,500 | 29,790,000 | 3.30% | +11,032,500 |
| BIOAGE LABS INC(BIOA) | 1,598,000 | 1,748,000 | +150,000 | 21,141,540 | 30,572,520 | 3.38% | +9,430,980 |
| KALVISTA PHARMACEUTICALS INC | 1,273,333 | 1,450,000 | +176,667 | 20,564,328 | 29,188,500 | 3.23% | +8,624,172 |
| COGENT BIOSCIENCES INC(COGT) | 2,350,000 | 2,350,000 | 0 | 83,472,000 | 90,451,500 | 10.01% | +6,979,500 |
| ARRIVENT BIOPHARMA INC(AVBP) | 1,971,054 | 1,971,054 | 0 | 39,657,606 | 45,472,216 | 5.03% | +5,814,610 |
| PRECISION BIOSCIENCES INC | 1,917,995 | 2,236,732 | +318,737 | 7,978,859 | 12,302,026 | 1.36% | +4,323,167 |
| PERSPECTIVE THERAPEUTICS INC | 0 | 791,555 | +791,555 | 0 | 3,300,784 | 0.37% | +3,300,784 |
| DBV TECHNOLOGIES S A | 574,200 | 574,200 | 0 | 11,007,414 | 11,995,038 | 1.33% | +987,624 |
| UNICYCIVE THERAPEUTICS INC | 1,000,000 | 1,000,000 | 0 | 5,770,000 | 6,580,000 | 0.73% | +810,000 |
| PALISADE BIO INC | 9,567,898 | 10,276,317 | +708,419 | 22,484,560 | 17,983,555 | 1.99% | -4,501,005 |
| PEPGEN INC | 700,000 | 0 | -700,000 | 4,557,000 | 0 | — | -4,557,000 |
| OCULAR THERAPEUTIX INC(OCUL) | 2,623,600 | 3,166,600 | +543,000 | 31,850,504 | 26,821,102 | 2.97% | -5,029,402 |
| EVOMMUNE INC | 500,000 | 143,472 | -356,528 | 8,560,000 | 3,298,421 | 0.37% | -5,261,579 |
| KYMERA THERAPEUTICS INC(KYMR) | 535,000 | 425,000 | -110,000 | 41,628,350 | 35,398,250 | 3.92% | -6,230,100 |
| BRIDGEBIO ONCOLOGY THERAPEUT | 1,043,110 | 719,000 | -324,110 | 13,059,737 | 6,435,050 | 0.71% | -6,624,687 |
| CORBUS PHARMACEUTICALS HLDGS | 955,000 | 0 | -955,000 | 7,773,700 | 0 | — | -7,773,700 |
| TAYSHA GENE THERAPIES INC(TSHA) | 8,859,911 | 8,859,911 | 0 | 48,729,511 | 39,603,802 | 4.38% | -9,125,709 |
| LEXEO THERAPEUTICS INC | 1,725,000 | 1,100,000 | -625,000 | 17,129,250 | 6,314,000 | 0.70% | -10,815,250 |
| PHARVARIS N V COM | 671,465 | 165,000 | -506,465 | 18,633,154 | 4,661,250 | 0.52% | -13,971,904 |
| TREVI THERAPEUTICS INC(TRVI) | 2,815,000 | 1,485,000 | -1,330,000 | 35,243,800 | 17,716,050 | 1.96% | -17,527,750 |
| RAPT THERAPEUTICS INC | 574,000 | 0 | -574,000 | 19,441,380 | 0 | — | -19,441,380 |
| CIDARA THERAPEUTICS INC | 100,000 | 0 | -100,000 | 22,089,000 | 0 | — | -22,089,000 |
| CG ONCOLOGY INC(CGON)(Call) | 600,000 | 0 | -600,000 | 24,912,000 | 0 | — | -24,912,000 |
| ABIVAX SA(ABVX) | 756,000 | 677,000 | -79,000 | 101,950,380 | 75,383,950 | 8.34% | -26,566,430 |
| MIND MEDICINE MINDMED INC | 2,230,000 | 0 | -2,230,000 | 29,859,700 | 0 | — | -29,859,700 |
| GOSSAMER BIO INC | 13,915,371 | 7,750,000 | -6,165,371 | 43,137,650 | 2,545,875 | 0.28% | -40,591,775 |