Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q3 2024 ▲▼ | Q4 2024 ▲▼ | Change ▲▼ | Q3 2024 ▲▼ | Q4 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| SCHOLAR ROCK HLDG CORP(SRRK) | 0 | 488,000 | +488,000 | 0 | 21,091 | 3.59% | +21,091 |
| MERUS N V | 0 | 308,000 | +308,000 | 0 | 12,951 | 2.20% | +12,951 |
| ERASCA INC(ERAS) | 0 | 5,136,795 | +5,136,795 | 0 | 12,893 | 2.19% | +12,893 |
| SYNDAX PHARMACEUTICALS INC(SNDX) | 0 | 904,000 | +904,000 | 0 | 11,951 | 2.03% | +11,951 |
| KALVISTA PHARMACEUTICALS INC | 0 | 1,370,000 | +1,370,000 | 0 | 11,604 | 1.97% | +11,604 |
| APELLIS PHARMACEUTICALS INC COM | 3,006,980 | 3,006,980 | 0 | 86,721 | 95,953 | 16.32% | +9,231 |
| TAYSHA GENE THERAPIES INC(TSHA) | 4,572,222 | 10,450,000 | +5,877,778 | 9,190 | 18,079 | 3.08% | +8,888 |
| ARRIVENT BIOPHARMA INC(AVBP) | 1,976,387 | 2,059,387 | +83,000 | 46,445 | 54,862 | 9.33% | +8,417 |
| GOSSAMER BIO INC(GOSS) | 9,187,883 | 18,350,000 | +9,162,117 | 9,063 | 16,599 | 2.82% | +7,536 |
| COGENT BIOSCIENCES INC(COGT) | 1,305,000 | 2,763,000 | +1,458,000 | 14,094 | 21,551 | 3.67% | +7,457 |
| DYNE THERAPEUTICS INC(DYN) | 262,726 | 668,000 | +405,274 | 9,437 | 15,738 | 2.68% | +6,301 |
| NEUROGENE INC(NGNE) | 15,000 | 303,000 | +288,000 | 629 | 6,927 | 1.18% | +6,297 |
| ALLOVIR INC | 0 | 11,215,000 | +11,215,000 | 0 | 4,710 | 0.80% | +4,710 |
| UNICYCIVE THERAPEUTICS INC | 8,559,000 | 10,000,000 | +1,441,000 | 3,491 | 7,942 | 1.35% | +4,451 |
| MIND MEDICINE MINDMED INC | 3,018,000 | 3,018,000 | 0 | 17,172 | 21,005 | 3.57% | +3,833 |
| PHARVARIS N V COM | 620,470 | 778,000 | +157,530 | 11,491 | 14,914 | 2.54% | +3,423 |
| ATYR PHARMA INC | 0 | 900,000 | +900,000 | 0 | 3,258 | 0.55% | +3,258 |
| CENTESSA PHARMACEUTICALS PLC | 2,012,052 | 1,993,052 | -19,000 | 32,173 | 33,384 | 5.68% | +1,211 |
| REGULUS THERAPEUTICS INC | 4,263,701 | 4,848,802 | +585,101 | 6,694 | 7,661 | 1.30% | +967 |
| NUVATION BIO INC(NUVB) | 312,336 | 312,336 | 0 | 715 | 831 | 0.14% | +116 |
| HELIX ACQUISITION CORP II | 250,000 | 250,000 | 0 | 2,612 | 2,625 | 0.45% | +13 |
| OCULAR THERAPEUTIX INC(OCUL) | 2,425,000 | 2,425,000 | 0 | 21,098 | 20,710 | 3.52% | -388 |
| MERSANA THERAPEUTICS INC | 992,000 | 992,000 | 0 | 1,875 | 1,419 | 0.24% | -456 |
| NKARTA INC(NKTX) | 120,000 | 0 | -120,000 | 542 | 0 | — | -542 |
| RAPT THERAPEUTICS INC | 292,000 | 0 | -292,000 | 587 | 0 | — | -587 |
| AUTOLUS THERAPEUTICS PLC(AUTL) | 176,000 | 0 | -176,000 | 639 | 0 | — | -639 |
| AEROVATE THERAPEUTICS INC | 465,440 | 0 | -465,440 | 973 | 0 | — | -973 |
| CENTURY THERAPEUTICS INC(IPSC) | 666,825 | 0 | -666,825 | 1,140 | 0 | — | -1,140 |
| DIANTHUS THERAPEUTICS INC(DNTH) | 1,746,667 | 2,110,167 | +363,500 | 47,824 | 46,002 | 7.82% | -1,822 |
| BRIDGEBIO PHARMA INC(BBIO) | 552,000 | 441,600 | -110,400 | 14,054 | 12,118 | 2.06% | -1,936 |
| ANNEXON INC(ANNX) | 400,000 | 0 | -400,000 | 2,368 | 0 | — | -2,368 |
| BLACK DIAMOND THERAPEUTICS I | 594,000 | 0 | -594,000 | 2,584 | 0 | — | -2,584 |
| VIRIDIAN THERAPEUTICS INC(VRDN) | 870,000 | 870,000 | 0 | 19,793 | 16,678 | 2.84% | -3,115 |
| PEPGEN INC(PEPG) | 376,117 | 0 | -376,117 | 3,216 | 0 | — | -3,216 |
| NUVATION BIO INC(NUVB) | 12,171,513 | 9,202,907 | -2,968,606 | 27,873 | 24,480 | 4.16% | -3,393 |
| RENEO PHARMACEUTICALS INC | 2,250,000 | 0 | -2,250,000 | 3,825 | 0 | — | -3,825 |
| CYBIN INC(HELP) | 489,596 | 0 | -489,596 | 4,353 | 0 | — | -4,353 |
| TENAYA THERAPEUTICS INC(TNYA) | 2,576,200 | 0 | -2,576,200 | 4,972 | 0 | — | -4,972 |
| VENTYX BIOSCIENCES INC | 2,391,114 | 0 | -2,391,114 | 5,213 | 0 | — | -5,213 |
| MINERALYS THERAPEUTICS INC(MLYS) | 600,000 | 0 | -600,000 | 7,266 | 0 | — | -7,266 |
| PRAXIS PRECISION MEDICINES I(PRAX) | 130,000 | 0 | -130,000 | 7,480 | 0 | — | -7,480 |
| EYEPOINT PHARMACEUTICALS INC(EYPT) | 1,093,503 | 0 | -1,093,503 | 8,737 | 0 | — | -8,737 |
| INSMED INC(INSM) | 436,820 | 332,000 | -104,820 | 31,888 | 22,921 | 3.90% | -8,967 |
| ALLOVIR INC | 11,202,000 | 0 | -11,202,000 | 9,057 | 0 | — | -9,057 |
| CORBUS PHARMACEUTICALS HLDGS(CRBP) | 1,115,000 | 1,115,000 | 0 | 23,002 | 13,157 | 2.24% | -9,845 |
| PERSPECTIVE THERAPEUTICS INC(CATX) | 1,422,224 | 2,304,752 | +882,528 | 18,987 | 7,352 | 1.25% | -11,635 |
| VERONA PHARMA PLC | 1,835,200 | 571,264 | -1,263,936 | 52,799 | 26,530 | 4.51% | -26,269 |
| STRUCTURE THERAPEUTICS INC | 1,198,000 | 0 | -1,198,000 | 52,580 | 0 | — | -52,580 |