Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| ABIVAX Société AnonymeADRS(ABVX) | 7,111,596 | 6,481,085 | -630,511 | $959.03M | $721.67M | 20.65% | -$237.37M |
| CG Oncology, Inc.COMM(CGON) | 3,670,206 | 3,670,206 | 0 | $152.39M | $248.40M | 7.11% | +$96.01M |
| Tango Therapeutics, Inc.COMM(TNGX) | 12,762,094 | 10,531,071 | -2,231,023 | $113.07M | $220.31M | 6.30% | +$107.24M |
| Cogent Biosciences, Inc.COMM(COGT) | 5,868,162 | 4,946,894 | -921,268 | $208.44M | $190.41M | 5.45% | -$18.03M |
| Centessa Pharmaceuticals PlcADRS | 4,286,480 | 4,286,480 | 0 | $107.20M | $170.26M | 4.87% | +$63.05M |
| Dianthus Therapeutics, Inc.COMM(DNTH) | 1,676,624 | 1,676,624 | 0 | $69.09M | $140.70M | 4.03% | +$71.61M |
| Tyra Biosciences, Inc.COMM(TYRA) | 2,898,103 | 3,248,980 | +350,877 | $76.19M | $124.44M | 3.56% | +$48.24M |
| Immunovant, Inc.COMM(IMVT) | 1,660,933 | 4,457,988 | +2,797,055 | $42.22M | $110.74M | 3.17% | +$68.52M |
| BioCryst Pharmaceuticals, Inc.COMM(BCRX) | 0 | 11,020,968 | +11,020,968 | $0 | $104.92M | 3.00% | +$104.92M |
| Mirum Pharmaceuticals, Inc.COMM(MIRM) | 62,049 | 1,062,049 | +1,000,000 | $4.90M | $98.11M | 2.81% | +$93.21M |
| Vor Biopharma Inc.COMM(VOR) | 0 | 5,673,078 | +5,673,078 | $0 | $96.50M | 2.76% | +$96.50M |
| Spyre Therapeutics, Inc.COMM(SYRE) | 1,900,582 | 1,900,582 | 0 | $62.26M | $95.87M | 2.74% | +$33.60M |
| Amylyx Pharmaceuticals, Inc.COMM(AMLX) | 6,243,812 | 6,243,812 | 0 | $75.43M | $86.79M | 2.48% | +$11.36M |
| Disc Medicine, Inc.COMM(IRON) | 0 | 1,341,862 | +1,341,862 | $0 | $85.80M | 2.45% | +$85.80M |
| Dyne Therapeutics, Inc.COMM(DYN) | 4,615,144 | 4,615,144 | 0 | $90.27M | $83.67M | 2.39% | -$6.60M |
| Monte Rosa Therapeutics, Inc.COMM(GLUE) | 4,622,151 | 4,622,151 | 0 | $72.48M | $76.03M | 2.18% | +$3.56M |
| Savara Inc.COMM(SVRA) | 12,362,205 | 12,362,205 | 0 | $74.54M | $67.50M | 1.93% | -$7.05M |
| Revolution Medicines, Inc.COMM(RVMD) | 436,473 | 576,473 | +140,000 | $34.77M | $56.06M | 1.60% | +$21.30M |
| Kodiak Sciences Inc.COMM(KOD) | 1,445,538 | 1,445,538 | 0 | $40.42M | $55.10M | 1.58% | +$14.69M |
| LB Pharmaceuticals IncCOMM(LBRX) | 1,745,015 | 1,839,489 | +94,474 | $38.84M | $45.28M | 1.30% | +$6.44M |
| Surrozen, Inc.COMM(SRZN) | 0 | 1,473,101 | +1,473,101 | $0 | $42.91M | 1.23% | +$42.91M |
| ADC Therapeutics SACOMM(ADCT) | 11,390,175 | 11,390,175 | 0 | $40.21M | $42.71M | 1.22% | +$2.51M |
| Relay Therapeutics, Inc.COMM(RLAY) | 3,220,186 | 4,273,356 | +1,053,170 | $27.24M | $42.52M | 1.22% | +$15.28M |
| Fulcrum Therapeutics, Inc.COMM(FULC) | 5,250,000 | 5,250,000 | 0 | $59.38M | $40.27M | 1.15% | -$19.11M |
| Biohaven Ltd.COMM(BHVN) | 4,631,317 | 4,631,317 | 0 | $52.29M | $39.18M | 1.12% | -$13.11M |
| Century Therapeutics, Inc.COMM(IPSC) | 0 | 17,754,430 | +17,754,430 | $0 | $39.02M | 1.12% | +$39.02M |
| Tectonic Therapeutic, Inc.COMM(TECX) | 0 | 1,204,891 | +1,204,891 | $0 | $37.24M | 1.07% | +$37.24M |
| Perspective Therapeutics, Inc.COMM(CATX) | 0 | 7,915,567 | +7,915,567 | $0 | $33.01M | 0.94% | +$33.01M |
| Xencor, Inc.COMM(XNCR) | 2,452,138 | 2,452,138 | 0 | $37.54M | $29.57M | 0.85% | -$7.97M |
| Entrada Therapeutics, Inc.COMM(TRDA) | 2,088,392 | 2,287,500 | +199,108 | $21.47M | $28.87M | 0.83% | +$7.40M |
| ALX Oncology Holdings Inc.COMM(ALXO) | 0 | 13,011,849 | +13,011,849 | $0 | $26.09M | 0.75% | +$26.09M |
| Arvinas, Inc.COMM(ARVN) | 2,666,216 | 2,387,461 | -278,755 | $31.62M | $25.31M | 0.72% | -$6.31M |
| Janux Therapeutics, Inc.COMM(JANX) | 1,789,617 | 1,789,617 | 0 | $24.70M | $24.88M | 0.71% | +$179.0K |
| AgomAb Therapeutics NVADRS(AGMB) | 0 | 2,053,233 | +2,053,233 | $0 | $21.54M | 0.62% | +$21.54M |
| Alector IncCOMM | 10,000,000 | 10,000,000 | 0 | $15.60M | $21.50M | 0.62% | +$5.90M |
| MBX Biosciences, Inc.COMM(MBX) | 650,000 | 650,000 | 0 | $20.50M | $19.40M | 0.56% | -$1.10M |
| Silence Therapeutics plcADRS(SLN) | 3,033,560 | 3,033,560 | 0 | $18.44M | $15.99M | 0.46% | -$2.46M |
| Liquidia CorporationCOMM(LQDA) | 1,710,084 | 403,048 | -1,307,036 | $58.98M | $15.21M | 0.44% | -$43.77M |
| Ocular Therapeutix, Inc.COMM(OCUL) | 5,740,231 | 1,647,752 | -4,092,479 | $69.69M | $13.96M | 0.40% | -$55.73M |
| Avalo Therapeutics, Inc.COMM(AVTX) | 483,000 | 738,383 | +255,383 | $8.77M | $11.02M | 0.32% | +$2.25M |
| UroGen Pharma Ltd.COMM(URGN) | 717,347 | 405,365 | -311,982 | $16.80M | $7.29M | 0.21% | -$9.51M |
| Monopar Therapeutics Inc.COMM(MNPR) | 141,915 | 132,103 | -9,812 | $9.27M | $7.24M | 0.21% | -$2.03M |
| Context Therapeutics Inc.COMM(CNTX) | 0 | 2,682,696 | +2,682,696 | $0 | $7.03M | 0.20% | +$7.03M |
| Structure Therapeutics IncADRS | 920,857 | 140,411 | -780,446 | $64.05M | $6.77M | 0.19% | -$57.28M |
| Cullinan Therapeutics, Inc.COMM(CGEM) | 0 | 406,786 | +406,786 | $0 | $5.78M | 0.17% | +$5.78M |
| Korro Bio, Inc.COMM(KRRO) | 416,301 | 416,301 | 0 | $3.33M | $4.71M | 0.13% | +$1.38M |
| LeonaBio, Inc.COMM(LONA) | 464,398 | 464,398 | 0 | $3.35M | $4.67M | 0.13% | +$1.32M |
| Upstream Bio, Inc.COMM(UPB) | 743,886 | 181,063 | -562,823 | $20.20M | $1.63M | 0.05% | -$18.57M |
| Vistagen Therapeutics, Inc.COMM(VTGN) | 2,676,580 | 2,676,580 | 0 | $1.77M | $1.53M | 0.04% | -$242.0K |
| Agios Pharmaceuticals, Inc.COMM(AGIO) | 1,181,841 | 0 | -1,181,841 | $32.17M | $0 | — | -$32.17M |
| EyePoint, Inc.COMM(EYPT) | 3,572,335 | 0 | -3,572,335 | $65.27M | $0 | — | -$65.27M |
| Maze Therapeutics, Inc.COMM(MAZE) | 173,816 | 0 | -173,816 | $7.20M | $0 | — | -$7.20M |
| Rapt Therapeutics IncCOMM | 2,582,408 | 0 | -2,582,408 | $87.47M | $0 | — | -$87.47M |
| Ventyx Biosciences IncCOMM | 316,195 | 0 | -316,195 | $2.86M | $0 | — | -$2.86M |