Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q2 2025 ▲▼ | Q3 2025 ▲▼ | Change ▲▼ | Q2 2025 ▲▼ | Q3 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| ABIVAX SA AMERICAN DEPOSITARY SHARES(ABVX) | 6,056,596 | 7,111,596 | +1,055,000 | 46,333 | 603,775 | 29.70% | +557,442 |
| CG ONCOLOGY INC(CGON) | 3,670,206 | 3,670,206 | 0 | 95,425 | 147,836 | 7.27% | +52,411 |
| COGENT BIOSCIENCES INC(COGT) | 6,964,375 | 6,798,162 | -166,213 | 50,004 | 97,622 | 4.80% | +47,617 |
| AMYLYX PHARMACEUTICALS INC(AMLX) | 5,943,812 | 6,243,812 | +300,000 | 38,100 | 84,853 | 4.17% | +46,754 |
| TOURMALINE BIO INC | 1,477,593 | 1,311,783 | -165,810 | 23,627 | 62,743 | 3.09% | +39,116 |
| LIQUIDIA TECHNOLOGIES INC(LQDA) | 0 | 1,710,084 | +1,710,084 | 0 | 38,887 | 1.91% | +38,887 |
| CENTESSA PHARMACEUTICALS PLC | 2,890,816 | 3,136,480 | +245,664 | 37,985 | 76,060 | 3.74% | +38,074 |
| DIANTHUS THERAPEUTICS INC(DNTH) | 1,501,624 | 1,676,624 | +175,000 | 27,975 | 65,975 | 3.25% | +38,000 |
| AGIOS PHARMACEUTICALS INC(AGIO) | 697,003 | 1,430,041 | +733,038 | 23,182 | 57,402 | 2.82% | +34,220 |
| RAPT THERAPEUTICS INC | 1,636,275 | 1,636,275 | 0 | 13,090 | 42,200 | 2.08% | +29,109 |
| LB PHARMACEUTICALS INC(LBRX) | 0 | 1,745,016 | +1,745,016 | 0 | 27,554 | 1.36% | +27,554 |
| DYNE THERAPEUTICS INC(DYN) | 3,766,660 | 4,615,144 | +848,484 | 35,859 | 58,382 | 2.87% | +22,523 |
| OCULAR THERAPEUTIX INC(OCUL) | 5,319,148 | 6,117,232 | +798,084 | 49,362 | 71,510 | 3.52% | +22,149 |
| REVOLUTION MEDICINES INC(RVMD) | 0 | 436,473 | +436,473 | 0 | 20,383 | 1.00% | +20,383 |
| KORRO BIO INC(KRRO) | 0 | 416,301 | +416,301 | 0 | 19,937 | 0.98% | +19,937 |
| SPYRE THERAPEUTICS INC(SYRE) | 0 | 1,100,582 | +1,100,582 | 0 | 18,446 | 0.91% | +18,446 |
| EYEPOINT PHARMACEUTICALS INC(EYPT) | 3,572,335 | 3,572,335 | 0 | 33,616 | 50,870 | 2.50% | +17,254 |
| TANGO THERAPEUTICS INC(TNGX) | 10,736,000 | 8,536,196 | -2,199,804 | 54,968 | 71,704 | 3.53% | +16,736 |
| SAVARA INC(SVRA) | 12,362,205 | 12,362,205 | 0 | 28,186 | 44,133 | 2.17% | +15,947 |
| KODIAK SCIENCES INC(KOD) | 1,145,538 | 1,145,538 | 0 | 4,273 | 18,752 | 0.92% | +14,480 |
| UROGEN PHARMA LTD(URGN) | 0 | 717,347 | +717,347 | 0 | 14,311 | 0.70% | +14,311 |
| ARVINAS HOLDING CO LLC(ARVN) | 0 | 1,617,365 | +1,617,365 | 0 | 13,780 | 0.68% | +13,780 |
| TYRA BIOSCIENCES INC(TYRA) | 2,898,103 | 2,898,103 | 0 | 27,735 | 40,544 | 1.99% | +12,810 |
| MONOPAR THERAPEUTICS INC(MNPR) | 0 | 153,000 | +153,000 | 0 | 12,496 | 0.61% | +12,496 |
| FULCRUM THERAPEUTICS INC(FULC) | 5,250,000 | 5,250,000 | 0 | 36,120 | 48,300 | 2.38% | +12,180 |
| XENCOR INC(XNCR) | 2,452,138 | 2,452,138 | 0 | 19,274 | 28,764 | 1.41% | +9,490 |
| RELAY THERAPEUTICS INC(RLAY) | 0 | 1,810,351 | +1,810,351 | 0 | 9,450 | 0.46% | +9,450 |
| UPSTREAM BIO INC(UPB) | 2,801,763 | 2,117,103 | -684,660 | 30,763 | 39,823 | 1.96% | +9,059 |
| STRUCTURE THERAPEUTICS INC | 1,063,000 | 1,063,000 | 0 | 22,047 | 29,764 | 1.46% | +7,717 |
| DISC MEDICINE INC(IRON) | 465,257 | 465,257 | 0 | 24,640 | 30,744 | 1.51% | +6,104 |
| ADC THERAPEUTICS SA(ADCT) | 0 | 1,390,175 | +1,390,175 | 0 | 5,561 | 0.27% | +5,561 |
| PEPGEN INC(PEPG) | 0 | 1,200,000 | +1,200,000 | 0 | 5,544 | 0.27% | +5,544 |
| ASTRIA THERAPEUTICS INC | 2,761,861 | 2,761,861 | 0 | 14,804 | 20,106 | 0.99% | +5,303 |
| VISTAGEN THERAPEUTICS INC(VTGN) | 2,676,580 | 2,676,580 | 0 | 5,353 | 9,502 | 0.47% | +4,149 |
| MBX BIOSCIENCES INC(MBX) | 650,000 | 650,000 | 0 | 7,417 | 11,375 | 0.56% | +3,959 |
| AVALO THERAPEUTICS INC(AVTX) | 483,000 | 483,000 | 0 | 2,410 | 6,139 | 0.30% | +3,729 |
| ADVERUM BIOTECHNOLOGIES INC | 1,796,482 | 1,668,174 | -128,308 | 3,862 | 7,557 | 0.37% | +3,694 |
| VENTYX BIOSCIENCES INC | 316,195 | 316,195 | 0 | 677 | 983 | 0.05% | +307 |
| KEROS THERAPEUTICS INC(KROS) | 0 | 0 | 0 | 0 | 0 | — | 0 |
| CABALETTA BIO INC(CABA) | 86,795 | 0 | -86,795 | 132 | 0 | — | -132 |
| ENTRADA THERAPEUTICS INC(TRDA) | 584,955 | 584,955 | 0 | 3,931 | 3,393 | 0.17% | -538 |
| JADE BIOSCIENCES INC | 64,023 | 0 | -64,023 | 640 | 0 | — | -640 |
| SILENCE THERAPEUTICS PLC(SLN) | 3,033,560 | 3,033,560 | 0 | 17,595 | 15,744 | 0.77% | -1,850 |
| KURA ONCOLOGY INC(KURA) | 735,184 | 0 | -735,184 | 4,242 | 0 | — | -4,242 |
| NEKTAR THERAPEUTICS(NKTR) | 266,666 | 0 | -266,666 | 6,891 | 0 | — | -6,891 |
| Enliven Therapeutics, Inc. | 498,000 | 0 | -498,000 | 9,990 | 0 | — | -9,990 |
| THIRD HARMONIC BIO INC | 1,915,424 | 0 | -1,915,424 | 10,401 | 0 | — | -10,401 |
| SOLENO THERAPEUTICS INC | 186,250 | 0 | -186,250 | 15,604 | 0 | — | -15,604 |
| CIDARA THERAPEUTICS INC | 1,005,901 | 0 | -1,005,901 | 48,997 | 0 | — | -48,997 |