Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| ABIVAX Société AnonymeADRS(ABVX) | 7,111,596 | 7,111,596 | 0 | $603.77M | $959.03M | 31.74% | +$355.26M |
| Cogent Biosciences, Inc.COMM(COGT) | 6,798,162 | 5,868,162 | -930,000 | $97.62M | $208.44M | 6.90% | +$110.82M |
| CG Oncology, Inc.COMM(CGON) | 3,670,206 | 3,670,206 | 0 | $147.84M | $152.39M | 5.04% | +$4.55M |
| Tango Therapeutics, Inc.COMM(TNGX) | 8,536,196 | 12,762,094 | +4,225,898 | $71.70M | $113.07M | 3.74% | +$41.37M |
| Centessa Pharmaceuticals PlcADRS | 3,136,480 | 4,286,480 | +1,150,000 | $76.06M | $107.20M | 3.55% | +$31.15M |
| Dyne Therapeutics, Inc.COMM(DYN) | 4,615,144 | 4,615,144 | 0 | $58.38M | $90.27M | 2.99% | +$31.89M |
| Rapt Therapeutics IncCOMM | 1,636,275 | 2,582,408 | +946,133 | $42.20M | $87.47M | 2.89% | +$45.27M |
| Tyra Biosciences, Inc.COMM(TYRA) | 2,898,103 | 2,898,103 | 0 | $40.54M | $76.19M | 2.52% | +$35.65M |
| Amylyx Pharmaceuticals, Inc.COMM(AMLX) | 6,243,812 | 6,243,812 | 0 | $84.85M | $75.43M | 2.50% | -$9.43M |
| Savara Inc.COMM(SVRA) | 12,362,205 | 12,362,205 | 0 | $44.13M | $74.54M | 2.47% | +$30.41M |
| Monte Rosa Therapeutics, Inc.COMM(GLUE) | 0 | 4,622,151 | +4,622,151 | $0 | $72.48M | 2.40% | +$72.48M |
| Ocular Therapeutix, Inc.COMM(OCUL) | 6,117,232 | 5,740,231 | -377,001 | $71.51M | $69.69M | 2.31% | -$1.82M |
| Dianthus Therapeutics, Inc.COMM(DNTH) | 1,676,624 | 1,676,624 | 0 | $65.98M | $69.09M | 2.29% | +$3.12M |
| EyePoint, Inc.COMM(EYPT) | 3,572,335 | 3,572,335 | 0 | $50.87M | $65.27M | 2.16% | +$14.40M |
| Structure Therapeutics IncADRS | 1,063,000 | 920,857 | -142,143 | $29.76M | $64.05M | 2.12% | +$34.28M |
| Spyre Therapeutics, Inc.COMM(SYRE) | 1,100,582 | 1,900,582 | +800,000 | $18.45M | $62.26M | 2.06% | +$43.82M |
| Fulcrum Therapeutics, Inc.COMM(FULC) | 5,250,000 | 5,250,000 | 0 | $48.30M | $59.38M | 1.97% | +$11.08M |
| Liquidia CorporationCOMM(LQDA) | 1,710,084 | 1,710,084 | 0 | $38.89M | $58.98M | 1.95% | +$20.09M |
| Biohaven Ltd.COMM(BHVN) | 0 | 4,631,317 | +4,631,317 | $0 | $52.29M | 1.73% | +$52.29M |
| Immunovant, Inc.COMM(IMVT) | 0 | 1,660,933 | +1,660,933 | $0 | $42.22M | 1.40% | +$42.22M |
| Kodiak Sciences Inc.COMM(KOD) | 1,145,538 | 1,445,538 | +300,000 | $18.75M | $40.42M | 1.34% | +$21.66M |
| ADC Therapeutics SACOMM(ADCT) | 1,390,175 | 11,390,175 | +10,000,000 | $5.56M | $40.21M | 1.33% | +$34.65M |
| LB Pharmaceuticals IncCOMM(LBRX) | 1,745,016 | 1,745,015 | -1 | $27.55M | $38.84M | 1.29% | +$11.29M |
| Xencor, Inc.COMM(XNCR) | 2,452,138 | 2,452,138 | 0 | $28.76M | $37.54M | 1.24% | +$8.78M |
| Revolution Medicines, Inc.COMM(RVMD) | 436,473 | 436,473 | 0 | $20.38M | $34.77M | 1.15% | +$14.38M |
| Agios Pharmaceuticals, Inc.COMM(AGIO) | 1,430,041 | 1,181,841 | -248,200 | $57.40M | $32.17M | 1.06% | -$25.23M |
| Arvinas, Inc.COMM(ARVN) | 1,617,365 | 2,666,216 | +1,048,851 | $13.78M | $31.62M | 1.05% | +$17.84M |
| Relay Therapeutics, Inc.COMM(RLAY) | 1,810,351 | 3,220,186 | +1,409,835 | $9.45M | $27.24M | 0.90% | +$17.79M |
| Janux Therapeutics, Inc.COMM(JANX) | 0 | 1,789,617 | +1,789,617 | $0 | $24.70M | 0.82% | +$24.70M |
| Entrada Therapeutics, Inc.COMM(TRDA) | 584,955 | 2,088,392 | +1,503,437 | $3.39M | $21.47M | 0.71% | +$18.08M |
| MBX Biosciences, Inc.COMM(MBX) | 650,000 | 650,000 | 0 | $11.38M | $20.50M | 0.68% | +$9.13M |
| Upstream Bio, Inc.COMM(UPB) | 2,117,103 | 743,886 | -1,373,217 | $39.82M | $20.20M | 0.67% | -$19.63M |
| Silence Therapeutics plcADRS(SLN) | 3,033,560 | 3,033,560 | 0 | $15.74M | $18.44M | 0.61% | +$2.70M |
| UroGen Pharma Ltd.COMM(URGN) | 717,347 | 717,347 | 0 | $14.31M | $16.80M | 0.56% | +$2.49M |
| Alector IncCOMM | 0 | 10,000,000 | +10,000,000 | $0 | $15.60M | 0.52% | +$15.60M |
| Monopar Therapeutics Inc.COMM(MNPR) | 153,000 | 141,915 | -11,085 | $12.50M | $9.27M | 0.31% | -$3.23M |
| Avalo Therapeutics, Inc.COMM(AVTX) | 483,000 | 483,000 | 0 | $6.14M | $8.77M | 0.29% | +$2.63M |
| Maze Therapeutics, Inc.COMM(MAZE) | 0 | 173,816 | +173,816 | $0 | $7.20M | 0.24% | +$7.20M |
| Mirum Pharmaceuticals, Inc.COMM(MIRM) | 0 | 62,049 | +62,049 | $0 | $4.90M | 0.16% | +$4.90M |
| LeonaBio, Inc.COMM(LONA) | 0 | 464,398 | +464,398 | $0 | $3.35M | 0.11% | +$3.35M |
| Korro Bio, Inc.COMM(KRRO) | 416,301 | 416,301 | 0 | $19.94M | $3.33M | 0.11% | -$16.60M |
| Ventyx Biosciences IncCOMM | 316,195 | 316,195 | 0 | $983.4K | $2.86M | 0.09% | +$1.87M |
| Vistagen Therapeutics, Inc.COMM(VTGN) | 2,676,580 | 2,676,580 | 0 | $9.50M | $1.77M | 0.06% | -$7.73M |
| Adverum Biotechnologies IncCOMM | 1,668,174 | 0 | -1,668,174 | $7.56M | $0 | — | -$7.56M |
| Astria Therapeutics IncCOMM | 2,761,861 | 0 | -2,761,861 | $20.11M | $0 | — | -$20.11M |
| Disc Medicine, Inc.COMM(IRON) | 465,257 | 0 | -465,257 | $30.74M | $0 | — | -$30.74M |
| PepGen Inc.COMM(PEPG) | 1,200,000 | 0 | -1,200,000 | $5.54M | $0 | — | -$5.54M |
| Tourmaline Bio IncCOMM | 1,311,783 | 0 | -1,311,783 | $62.74M | $0 | — | -$62.74M |