Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Arcellx Inc COMMON STOCK | 5,724,016 | 5,774,016 | +50,000 | $373.21M | $662.97M | 13.55% | +$289.77M |
| Revolution Medicines, Inc.(RVMD) | 6,644,403 | 6,655,703 | +11,300 | $529.23M | $647.27M | 13.23% | +$118.04M |
| Nuvalent Inc | 5,269,433 | 5,324,433 | +55,000 | $530.05M | $545.49M | 11.15% | +$15.44M |
| Vaxcyte, Inc.(PCVX) | 4,068,020 | 4,793,020 | +725,000 | $187.70M | $278.52M | 5.69% | +$90.82M |
| Edgewise Therapeutics, Inc.(EWTX) | 6,541,210 | 7,365,038 | +823,828 | $162.32M | $232.00M | 4.74% | +$69.68M |
| Genmab A/SADS(GMAB) | 7,039,834 | 7,967,836 | +928,002 | $216.83M | $213.78M | 4.37% | -$3.05M |
| Insmed Incorporated(INSM) | 0 | 1,254,488 | +1,254,488 | $0 | $205.13M | 4.19% | +$205.13M |
| Tarsus Pharmaceuticals, Inc.(TARS) | 2,562,154 | 2,562,154 | 0 | $209.79M | $179.74M | 3.67% | -$30.05M |
| Belite Bio, IncADS(BLTE) | 0 | 1,114,784 | +1,114,784 | $0 | $177.74M | 3.63% | +$177.74M |
| Erasca, Inc.(ERAS) | 14,159,095 | 10,392,702 | -3,766,393 | $52.67M | $168.15M | 3.44% | +$115.48M |
| Centessa Pharmaceuticals PlcADS | 0 | 3,574,048 | +3,574,048 | $0 | $141.96M | 2.90% | +$141.96M |
| Olema Pharmaceuticals, Inc.(OLMA) | 7,544,172 | 8,020,576 | +476,404 | $188.60M | $119.59M | 2.44% | -$69.02M |
| Terns Pharmaceuticals Inc | 810,286 | 2,216,499 | +1,406,213 | $32.74M | $116.85M | 2.39% | +$84.12M |
| Oruka Therapeutics, Inc.(ORKA) | 1,710,316 | 2,320,316 | +610,000 | $51.84M | $113.81M | 2.33% | +$61.97M |
| Apogee Therapeutics Inc | 1,123,243 | 1,348,243 | +225,000 | $84.78M | $113.48M | 2.32% | +$28.70M |
| Spyre Therapeutics, Inc.(SYRE) | 1,467,266 | 1,957,266 | +490,000 | $48.07M | $98.72M | 2.02% | +$50.66M |
| Cytokinetics, Incorporated(CYTK) | 0 | 1,480,857 | +1,480,857 | $0 | $97.60M | 1.99% | +$97.60M |
| ABIVAX Société AnonymeADS(ABVX) | 1,417,473 | 772,473 | -645,000 | $191.15M | $86.01M | 1.76% | -$105.14M |
| Tango Therapeutics, Inc.(TNGX) | 0 | 4,009,679 | +4,009,679 | $0 | $83.88M | 1.71% | +$83.88M |
| Maze Therapeutics, Inc.(MAZE) | 0 | 2,744,399 | +2,744,399 | $0 | $81.92M | 1.67% | +$81.92M |
| Tyra Biosciences, Inc.(TYRA) | 0 | 2,054,991 | +2,054,991 | $0 | $78.71M | 1.61% | +$78.71M |
| Viridian Therapeutics, Inc.(VRDN) | 1,443,102 | 3,148,893 | +1,705,791 | $44.91M | $61.59M | 1.26% | +$16.68M |
| Scholar Rock Holding Corporation(SRRK) | 3,062,157 | 1,226,080 | -1,836,077 | $134.89M | $60.27M | 1.23% | -$74.61M |
| Mirum Pharmaceuticals, Inc.(MIRM) | 0 | 625,000 | +625,000 | $0 | $57.74M | 1.18% | +$57.74M |
| EyePoint, Inc.(EYPT) | 3,691,475 | 3,142,437 | -549,038 | $67.44M | $40.51M | 0.83% | -$26.94M |
| Lexeo Therapeutics, Inc.(LXEO) | 4,763,198 | 6,184,134 | +1,420,936 | $47.30M | $35.50M | 0.73% | -$11.80M |
| Veradermics, Incorporated(MANE) | 0 | 525,000 | +525,000 | $0 | $33.15M | 0.68% | +$33.15M |
| Vor Biopharma Inc.(VOR) | 1,750,000 | 1,750,000 | 0 | $22.89M | $31.22M | 0.64% | +$8.33M |
| UroGen Pharma Ltd.(URGN) | 4,473,648 | 1,703,949 | -2,769,699 | $104.77M | $30.64M | 0.63% | -$74.14M |
| Structure Therapeutics IncADS | 0 | 545,287 | +545,287 | $0 | $26.28M | 0.54% | +$26.28M |
| Inventiva S.A.ADS(IVA) | 4,000,000 | 4,000,000 | 0 | $18.60M | $22.20M | 0.45% | +$3.60M |
| ORIC Pharmaceuticals, Inc.(ORIC) | 2,401,217 | 1,701,217 | -700,000 | $19.64M | $21.55M | 0.44% | +$1.91M |
| Assembly Biosciences Inc | 665,251 | 665,251 | 0 | $22.63M | $18.46M | 0.38% | -$4.16M |
| BridgeBio Oncology Therapeutics, Inc.(BBOT) | 2,261,749 | 868,213 | -1,393,536 | $28.32M | $7.77M | 0.16% | -$20.55M |
| Kalaris Therapeutics, Inc.(KLRS) | 700,000 | 700,000 | 0 | $5.91M | $4.04M | 0.08% | -$1.87M |
| BridgeBio Pharma, Inc.(BBIO) | 684,277 | 0 | -684,277 | $52.34M | $0 | — | -$52.34M |
| Cidara Therapeutics Inc | 759,565 | 0 | -759,565 | $167.78M | $0 | — | -$167.78M |
| Crinetics Pharmaceuticals In | 2,210,774 | 0 | -2,210,774 | $102.91M | $0 | — | -$102.91M |
| Ocular Therapeutix, Inc.(OCUL) | 2,935,284 | 0 | -2,935,284 | $35.63M | $0 | — | -$35.63M |